PubRank

Arend Sidow

Author PubWeight™ 274.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 75.09
2 Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 2004 24.40
3 LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA. Genome Res 2003 23.03
4 Distribution and intensity of constraint in mammalian genomic sequence. Genome Res 2005 18.85
5 Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data. Nat Methods 2008 11.61
6 SHRiMP: accurate mapping of short color-space reads. PLoS Comput Biol 2009 11.24
7 ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res 2012 9.13
8 Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS Comput Biol 2010 8.69
9 A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning. Genome Res 2008 7.77
10 Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res 2007 7.05
11 Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity. Genome Res 2005 5.62
12 Determinants of nucleosome organization in primary human cells. Nature 2011 5.50
13 Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 2009 5.26
14 Single-nucleotide evolutionary constraint scores highlight disease-causing mutations. Nat Methods 2010 4.51
15 Characterization of evolutionary rates and constraints in three Mammalian genomes. Genome Res 2004 4.45
16 Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements. Genome Res 2012 3.61
17 Quantitative estimates of sequence divergence for comparative analyses of mammalian genomes. Genome Res 2003 3.52
18 Automated whole-genome multiple alignment of rat, mouse, and human. Genome Res 2004 2.64
19 Inference of functional regions in proteins by quantification of evolutionary constraints. Proc Natl Acad Sci U S A 2002 2.54
20 Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome. Proc Natl Acad Sci U S A 2010 2.45
21 Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes. Genome Res 2010 2.31
22 Extreme genomic variation in a natural population. Proc Natl Acad Sci U S A 2007 2.24
23 Genomic regulatory regions: insights from comparative sequence analysis. Curr Opin Genet Dev 2003 2.05
24 Trade-offs in detecting evolutionarily constrained sequence by comparative genomics. Annu Rev Genomics Hum Genet 2005 2.05
25 3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. PLoS One 2010 1.91
26 Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses. Genes Dev 2013 1.88
27 The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. Proc Natl Acad Sci U S A 2003 1.86
28 The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes. Genome Res 2013 1.83
29 A haplome alignment and reference sequence of the highly polymorphic Ciona savignyi genome. Genome Biol 2007 1.82
30 Functional architecture and evolution of transcriptional elements that drive gene coexpression. Science 2007 1.51
31 Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance. Genome Res 2004 1.47
32 Genome evolution during progression to breast cancer. Genome Res 2013 1.37
33 ProPhylER: a curated online resource for protein function and structure based on evolutionary constraint analyses. Genome Res 2009 1.35
34 Structural and molecular evolutionary analysis of Agouti and Agouti-related proteins. Chem Biol 2006 1.27
35 Functional evolution in the ancestral lineage of vertebrates or when genomic complexity was wagging its morphological tail. J Struct Funct Genomics 2003 1.18
36 ABC: software for interactive browsing of genomic multiple sequence alignment data. BMC Bioinformatics 2004 1.14
37 A cell cycle phosphoproteome of the yeast centrosome. Science 2011 1.13
38 De novo discovery of a tissue-specific gene regulatory module in a chordate. Genome Res 2005 1.02
39 Constructing a meaningful evolutionary average at the phylogenetic center of mass. BMC Bioinformatics 2007 1.02
40 Phenotype-genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence. Proc Natl Acad Sci U S A 2005 0.95
41 Transcription-factor occupancy at HOT regions quantitatively predicts RNA polymerase recruitment in five human cell lines. BMC Genomics 2013 0.93
42 An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo. Epigenetics Chromatin 2010 0.91
43 Inference of tumor phylogenies with improved somatic mutation discovery. J Comput Biol 2013 0.89
44 The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution. Genome Res 2008 0.89
45 Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members. BMC Evol Biol 2008 0.88
46 Discovery of recurrent structural variants in nasopharyngeal carcinoma. Genome Res 2013 0.81
47 Mammalian comparative sequence analysis of the Agrp locus. PLoS One 2007 0.77
48 The future of sequencing: convergence of intelligent design and market Darwinism. Genome Biol 2014 0.76