Published in Genes Dev on May 01, 2013
Self-consumption: the interplay of autophagy and apoptosis. Nat Rev Mol Cell Biol (2014) 3.38
Unravelling mechanisms of p53-mediated tumour suppression. Nat Rev Cancer (2014) 3.37
Autophagy-mediated tumor promotion. Cell (2013) 2.08
Oxidative stress and autophagy: the clash between damage and metabolic needs. Cell Death Differ (2014) 2.00
Cell biology. Metabolic control of cell death. Science (2014) 1.98
An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model. Genes Dev (2016) 1.70
IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo. Nature (2014) 1.66
Mitochondrial dysfunction in cancer. Front Oncol (2013) 1.57
Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2. Genome Biol (2013) 1.47
Neat1 is a p53-inducible lincRNA essential for transformation suppression. Genes Dev (2017) 1.39
Emerging strategies to effectively target autophagy in cancer. Oncogene (2015) 1.26
The transcription factor p53: not a repressor, solely an activator. Cell Cycle (2014) 1.23
Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature. Nat Commun (2014) 1.18
How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy. Trends Cell Biol (2015) 1.16
Inappropriate p53 activation during development induces features of CHARGE syndrome. Nature (2014) 1.04
Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Res (2015) 1.02
The functional and pathologic relevance of autophagy proteases. J Clin Invest (2015) 1.01
Lysosome: regulator of lipid degradation pathways. Trends Cell Biol (2014) 0.99
Survival or death: disequilibrating the oncogenic and tumor suppressive autophagy in cancer. Cell Death Dis (2013) 0.99
Autophagy in acute kidney injury. Semin Nephrol (2013) 0.98
Autophagy in DNA damage response. Int J Mol Sci (2015) 0.93
TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity. Genome Res (2014) 0.93
HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Dev Cell (2015) 0.91
The role of tumor suppressor p53 in the antioxidant defense and metabolism. Subcell Biochem (2014) 0.90
p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress. Cell Death Differ (2014) 0.89
The family that eats together stays together: new p53 family transcriptional targets in autophagy. Genes Dev (2013) 0.89
Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo. Oncotarget (2015) 0.89
Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance. Cell Death Differ (2016) 0.88
The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development. Cancer Discov (2015) 0.87
p53 as guardian of the mitochondrial genome. FEBS Lett (2016) 0.87
Recent insights into the function of autophagy in cancer. Genes Dev (2016) 0.86
Wip1 phosphatase: between p53 and MAPK kinases pathways. Oncotarget (2016) 0.86
Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT. J Clin Invest (2015) 0.85
DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization. Elife (2015) 0.85
Mechanisms of ferroptosis. Cell Mol Life Sci (2016) 0.84
MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors. Oncotarget (2016) 0.84
Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Biol Open (2015) 0.83
p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia. Br J Cancer (2013) 0.82
An inducible long noncoding RNA amplifies DNA damage signaling. Nat Genet (2016) 0.81
Evidence for site-specific occupancy of the mitochondrial genome by nuclear transcription factors. PLoS One (2014) 0.81
Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres. EMBO J (2015) 0.81
Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells. Elife (2015) 0.81
The DNA damage response: the omics era and its impact. DNA Repair (Amst) (2014) 0.80
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PLoS Genet (2015) 0.80
FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation. Genes Dev (2015) 0.80
Autophagy and radiosensitization in cancer. EXCLI J (2014) 0.79
PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function. Mol Cell Biol (2015) 0.79
Autophagy and p53. Cold Spring Harb Perspect Med (2016) 0.79
p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing. J Clin Invest (2016) 0.78
Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function. Cell Rep (2015) 0.78
The Transcriptional Landscape of p53 Signalling Pathway. EBioMedicine (2017) 0.78
Autophagy and Tubular Cell Death in the Kidney. Semin Nephrol (2016) 0.77
Census and evaluation of p53 target genes. Oncogene (2017) 0.77
Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas. Oncogene (2017) 0.77
Autophagy and the Cell Cycle: A Complex Landscape. Front Oncol (2017) 0.77
HPV16 E5 deregulates the autophagic process in human keratinocytes. Oncotarget (2015) 0.77
The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation. BMC Genomics (2016) 0.77
Tumor Protein (TP)-p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure. Mar Drugs (2016) 0.77
The regulation of autophagy during exercise in skeletal muscle. J Appl Physiol (1985) (2015) 0.77
p53 binding to human genome: crowd control navigation in chromatin context. Front Genet (2014) 0.77
Endosome traffic machinery meets the p53-p21 axis. Mol Cell Oncol (2015) 0.76
The putative oncotarget CSN5 controls a transcription-uncorrelated p53-mediated autophagy implicated in cancer cell survival under curcumin treatment. Oncotarget (2016) 0.76
Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB. Oncotarget (2015) 0.75
The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy. Br J Cancer (2016) 0.75
Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB. Oncotarget (2016) 0.75
Analysis of the p53/CEP-1 regulated non-coding transcriptome in C. elegans by an NSR-seq strategy. Protein Cell (2014) 0.75
A pathway of targeted autophagy is induced by DNA damage in budding yeast. Proc Natl Acad Sci U S A (2017) 0.75
LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56. Mol Cell (2016) 0.75
The double benefit of Spalax p53: surviving underground hypoxia while defying lung cancer cells in vitro via autophagy and caspase-dependent cell death. Oncotarget (2016) 0.75
Two p53 tetramers bind one consensus DNA response element. Nucleic Acids Res (2016) 0.75
Is Huntingtin Dispensable in the Adult Brain? J Huntingtons Dis (2017) 0.75
Common γ-chain cytokine signaling is required for macroautophagy induction during CD4(+) T-cell activation. Autophagy (2015) 0.75
p53 Specifically Binds Triplex DNA In Vitro and in Cells. PLoS One (2016) 0.75
Differential Protein Distribution between the Nucleus and Mitochondria: Implications in Aging. Front Genet (2016) 0.75
ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy. Oncotarget (2017) 0.75
Recognition of Local DNA Structures by p53 Protein. Int J Mol Sci (2017) 0.75
Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells. Curr Genomics (2017) 0.75
Drosophila IRBP bZIP heterodimer binds P-element DNA and affects hybrid dysgenesis. Proc Natl Acad Sci U S A (2016) 0.75
Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev (2017) 0.75
Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. Elife (2016) 0.75
Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance. Elife (2016) 0.75
Developing a Gene Biomarker at the Tipping Point of Adaptive and Adverse Responses in Human Bronchial Epithelial Cells. PLoS One (2016) 0.75
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity. Genome Res (2017) 0.75
A novel role for p53 in self-tolerance. Blood (2017) 0.75
Breaking fat: The regulation and mechanisms of lipophagy. Biochim Biophys Acta (2017) 0.75
Autophagy in the placenta. Obstet Gynecol Sci (2017) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Genome-wide mapping of in vivo protein-DNA interactions. Science (2007) 64.92
Differential expression analysis for sequence count data. Genome Biol (2010) 64.56
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res (2008) 54.83
Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol (1994) 37.96
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature (2006) 24.39
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell (1992) 19.87
Blinded by the Light: The Growing Complexity of p53. Cell (2009) 17.75
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A (2003) 15.59
Live or let die: the cell's response to p53. Nat Rev Cancer (2002) 15.06
Autophagy and the integrated stress response. Mol Cell (2010) 11.21
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Mol Cell (2005) 11.19
Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol (2008) 11.05
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell (2006) 9.47
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell (2004) 8.48
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev (2011) 7.43
The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci U S A (2005) 7.38
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell (2004) 7.22
Dissecting p53 tumor suppressor functions in vivo. Cancer Cell (2002) 6.24
Pancreatic cancers require autophagy for tumor growth. Genes Dev (2011) 6.17
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev (1993) 6.02
Regulation of autophagy by cytoplasmic p53. Nat Cell Biol (2008) 5.97
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev (1993) 5.33
Autophagy modulation as a potential therapeutic target for diverse diseases. Nat Rev Drug Discov (2012) 5.26
TP53 mutations in human cancers: origins, consequences, and clinical use. Cold Spring Harb Perspect Biol (2010) 4.92
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression. Cell (2011) 4.74
Autophagy-deficient mice develop multiple liver tumors. Genes Dev (2011) 4.64
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature (2002) 4.56
The role of apoptosis in cancer development and treatment response. Nat Rev Cancer (2005) 4.19
p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell (1994) 3.69
The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res (2007) 3.55
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol Cell (2002) 3.29
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L). Autophagy (2007) 3.08
Stage-specific sensitivity to p53 restoration during lung cancer progression. Nature (2010) 3.03
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science (1999) 2.96
Characterization of genome-wide p53-binding sites upon stress response. Nucleic Acids Res (2008) 2.67
The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality. Nat Genet (2005) 2.66
Autophagy regulation by p53. Curr Opin Cell Biol (2010) 2.56
C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell (2010) 2.50
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proc Natl Acad Sci U S A (1994) 2.37
Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules. Nat Protoc (2008) 2.17
Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus. PLoS Genet (2010) 2.14
Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle (2011) 2.01
Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells. Mol Cell (2012) 1.94
ASPP: a new family of oncogenes and tumour suppressor genes. Br J Cancer (2007) 1.94
3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. PLoS One (2010) 1.91
The origins and evolution of the p53 family of genes. Cold Spring Harb Perspect Biol (2009) 1.90
PUMA- and Bax-induced autophagy contributes to apoptosis. Cell Death Differ (2009) 1.83
Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis. Cell Death Differ (2012) 1.81
p53 and ATM: cell cycle, cell death, and cancer. Adv Cancer Res (1997) 1.77
p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation. Proc Natl Acad Sci U S A (2010) 1.77
Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation. J Biol Chem (2011) 1.74
Deconstructing p53 transcriptional networks in tumor suppression. Trends Cell Biol (2011) 1.62
Role of p53 serine 46 in p53 target gene regulation. PLoS One (2011) 1.48
A genomewide study identifies the Wnt signaling pathway as a major target of p53 in murine embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.41
p53-mediated inhibition of angiogenesis through up-regulation of a collagen prolyl hydroxylase. Science (2006) 1.40
Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death. Cell Death Differ (2011) 1.33
mTOR regulates autophagy-associated genes downstream of p73. Autophagy (2009) 1.31
Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity. Oncogene (1998) 1.22
Phylogeny and function of the invertebrate p53 superfamily. Cold Spring Harb Perspect Biol (2010) 1.19
In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models. Carcinogenesis (2010) 1.14
p53 inactivation by MDM2 and MDMX negative feedback loops in testicular germ cell tumors. Cell Cycle (2010) 1.06
Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis. Proc Natl Acad Sci U S A (2011) 0.97
ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy. Mol Cancer (2010) 0.92
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNA. Genome Res (2003) 23.03
Distribution and intensity of constraint in mammalian genomic sequence. Genome Res (2005) 18.85
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
Genome-wide analysis of transcription factor binding sites based on ChIP-Seq data. Nat Methods (2008) 11.61
SHRiMP: accurate mapping of short color-space reads. PLoS Comput Biol (2009) 11.24
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res (2012) 9.13
Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS Comput Biol (2010) 8.69
A high-resolution, nucleosome position map of C. elegans reveals a lack of universal sequence-dictated positioning. Genome Res (2008) 7.77
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res (2007) 7.05
Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity. Genome Res (2005) 5.62
Determinants of nucleosome organization in primary human cells. Nature (2011) 5.50
Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell (2009) 5.26
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression. Cell (2011) 4.74
Single-nucleotide evolutionary constraint scores highlight disease-causing mutations. Nat Methods (2010) 4.51
Characterization of evolutionary rates and constraints in three Mammalian genomes. Genome Res (2004) 4.45
The role of apoptosis in cancer development and treatment response. Nat Rev Cancer (2005) 4.19
Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. Nat Genet (2008) 4.02
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements. Genome Res (2012) 3.61
Quantitative estimates of sequence divergence for comparative analyses of mammalian genomes. Genome Res (2003) 3.52
The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality. Nat Genet (2005) 2.66
Automated whole-genome multiple alignment of rat, mouse, and human. Genome Res (2004) 2.64
Perp is a p63-regulated gene essential for epithelial integrity. Cell (2005) 2.58
Inference of functional regions in proteins by quantification of evolutionary constraints. Proc Natl Acad Sci U S A (2002) 2.54
Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome. Proc Natl Acad Sci U S A (2010) 2.45
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes. Genome Res (2010) 2.31
Extreme genomic variation in a natural population. Proc Natl Acad Sci U S A (2007) 2.24
Developmental context determines latency of MYC-induced tumorigenesis. PLoS Biol (2004) 2.05
Genomic regulatory regions: insights from comparative sequence analysis. Curr Opin Genet Dev (2003) 2.05
Trade-offs in detecting evolutionarily constrained sequence by comparative genomics. Annu Rev Genomics Hum Genet (2005) 2.05
3'-end sequencing for expression quantification (3SEQ) from archival tumor samples. PLoS One (2010) 1.91
p53 at a glance. J Cell Sci (2010) 1.88
The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation. Mol Cell (2008) 1.88
The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels. Proc Natl Acad Sci U S A (2003) 1.86
The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes. Genome Res (2013) 1.83
A haplome alignment and reference sequence of the highly polymorphic Ciona savignyi genome. Genome Biol (2007) 1.82
Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis. J Cell Biol (2009) 1.73
Deconstructing p53 transcriptional networks in tumor suppression. Trends Cell Biol (2011) 1.62
Functional architecture and evolution of transcriptional elements that drive gene coexpression. Science (2007) 1.51
Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance. Genome Res (2004) 1.47
Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389. Mol Cell Biol (2004) 1.44
Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies. J Invest Dermatol (2009) 1.44
Genome-wide analysis of p53 under hypoxic conditions. Mol Cell Biol (2006) 1.37
Genome evolution during progression to breast cancer. Genome Res (2013) 1.37
ProPhylER: a curated online resource for protein function and structure based on evolutionary constraint analyses. Genome Res (2009) 1.35
Desmosomes: new perpetrators in tumour suppression. Nat Rev Cancer (2011) 1.33
Structural and molecular evolutionary analysis of Agouti and Agouti-related proteins. Chem Biol (2006) 1.27
Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer. Biochem Biophys Res Commun (2005) 1.20
Functional evolution in the ancestral lineage of vertebrates or when genomic complexity was wagging its morphological tail. J Struct Funct Genomics (2003) 1.18
Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion. Differentiation (2004) 1.17
ABC: software for interactive browsing of genomic multiple sequence alignment data. BMC Bioinformatics (2004) 1.14
In vivo analysis of p53 tumor suppressor function using genetically engineered mouse models. Carcinogenesis (2010) 1.14
A cell cycle phosphoproteome of the yeast centrosome. Science (2011) 1.13
Multiple response elements and differential p53 binding control Perp expression during apoptosis. Mol Cancer Res (2003) 1.11
Perp is a mediator of p53-dependent apoptosis in diverse cell types. Curr Biol (2003) 1.11
A C-terminal domain targets the Pseudomonas aeruginosa cytotoxin ExoU to the plasma membrane of host cells. Infect Immun (2006) 1.09
Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence. Proc Natl Acad Sci U S A (2008) 1.05
Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis. PLoS Genet (2010) 1.04
De novo discovery of a tissue-specific gene regulatory module in a chordate. Genome Res (2005) 1.02
Constructing a meaningful evolutionary average at the phylogenetic center of mass. BMC Bioinformatics (2007) 1.02
Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage. Cancer Res (2007) 1.01
Phenotype-genotype correlation in Hirschsprung disease is illuminated by comparative analysis of the RET protein sequence. Proc Natl Acad Sci U S A (2005) 0.95
Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages. Proc Natl Acad Sci U S A (2011) 0.95
International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. Am J Med Genet A (2009) 0.94
Transcription-factor occupancy at HOT regions quantitatively predicts RNA polymerase recruitment in five human cell lines. BMC Genomics (2013) 0.93
An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo. Epigenetics Chromatin (2010) 0.91
Perp-etrating p53-dependent apoptosis. Cell Cycle (2004) 0.90
Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer. Breast Cancer Res (2012) 0.90
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development. Cancer Res (2005) 0.90
A new Perp in the lineup: linking p63 and desmosomal adhesion. Cell Cycle (2005) 0.90
The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution. Genome Res (2008) 0.89
Inference of tumor phylogenies with improved somatic mutation discovery. J Comput Biol (2013) 0.89
PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci (2011) 0.89
Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members. BMC Evol Biol (2008) 0.88
p63, cell adhesion and survival. Cell Cycle (2007) 0.88
Conquering the complexity of p53. Nat Genet (2004) 0.85
Differential PERP regulation by TP63 mutants provides insight into AEC pathogenesis. Am J Med Genet A (2009) 0.84
SKP-ing TAp63: stem cell depletion, senescence, and premature aging. Cell Stem Cell (2009) 0.84
Risk factors, prognostic indicators, and outcome of pyothorax in cats: 80 cases (1986-1999). J Am Vet Med Assoc (2002) 0.84
Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice. PLoS One (2012) 0.82
Discovery of recurrent structural variants in nasopharyngeal carcinoma. Genome Res (2013) 0.81
Measurement of Haemophilus influenzae type a capsular polysaccharide antibodies in cord blood sera. Pediatr Infect Dis J (2012) 0.80
TRP53 activates a global autophagy program to promote tumor suppression. Autophagy (2013) 0.80
Engaging the p53 metabolic brake drives senescence. Cell Res (2013) 0.80
Tumor suppression: p53 alters immune surveillance to restrain liver cancer. Curr Biol (2013) 0.80
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest (2016) 0.79
The requirement for perp in postnatal viability and epithelial integrity reflects an intrinsic role in stratified epithelia. J Invest Dermatol (2006) 0.79
p53QS: an old mutant teaches us new tricks. Cell Cycle (2005) 0.78
Loss of the desmosomal component perp impairs wound healing in vivo. Dermatol Res Pract (2010) 0.78
Guilty as CHARGED: p53's expanding role in disease. Cell Cycle (2014) 0.77
Mammalian comparative sequence analysis of the Agrp locus. PLoS One (2007) 0.77
The future of sequencing: convergence of intelligent design and market Darwinism. Genome Biol (2014) 0.76
Local and systemic complications in a cat after poorly performed dental extractions. J Vet Dent (2004) 0.76
A healthy tan? N Engl J Med (2007) 0.76