Karl-Ludwig Laugwitz

Author PubWeight™ 97.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med 2010 9.19
2 Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 2006 7.21
3 Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med 2014 4.94
4 The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell 2007 3.54
5 Paclitaxel-eluting balloons, paclitaxel-eluting stents, and balloon angioplasty in patients with restenosis after implantation of a drug-eluting stent (ISAR-DESIRE 3): a randomised, open-label trial. Lancet 2012 3.12
6 Validation of the Bleeding Academic Research Consortium definition of bleeding in patients with coronary artery disease undergoing percutaneous coronary intervention. Circulation 2012 2.32
7 Drug-eluting versus bare-metal stents in saphenous vein graft lesions (ISAR-CABG): a randomised controlled superiority trial. Lancet 2011 2.10
8 Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med 2012 1.93
9 Randomized trial of paclitaxel- versus sirolimus-eluting stents for treatment of coronary restenosis in sirolimus-eluting stents: the ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) study. J Am Coll Cardiol 2010 1.93
10 Randomized, non-inferiority trial of three limus agent-eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents (ISAR-TEST-4) Trial. Eur Heart J 2009 1.81
11 Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol 2009 1.73
12 Prognostic value of sensitive troponin T in patients with stable and unstable angina and undetectable conventional troponin. Am Heart J 2011 1.70
13 ISAR-REACT 3A: a study of reduced dose of unfractionated heparin in biomarker negative patients undergoing percutaneous coronary intervention. Eur Heart J 2010 1.56
14 One-year outcomes with abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary interventions in patients with non-ST-segment elevation myocardial infarction: updated results from the ISAR-REACT 4 trial. EuroIntervention 2013 1.47
15 Bare metal vs. drug-eluting stents for extracranial vertebral artery disease: a meta-analysis of nonrandomized comparative studies. J Endovasc Ther 2014 1.43
16 Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors. FASEB J 2009 1.43
17 Gene transfer of the pancaspase inhibitor P35 reduces myocardial infarct size and improves cardiac function. J Mol Med (Berl) 2005 1.42
18 Randomised, double-blind trial on the value of tapered discontinuation of clopidogrel maintenance therapy after drug-eluting stent implantation. Intracoronary Stenting and Antithrombotic Regimen: CAUTION in Discontinuing Clopidogrel Therapy--ISAR-CAUTION. Thromb Haemost 2014 1.42
19 Incidence and prognostic value of bleeding after percutaneous coronary intervention in patients older than 75 years of age. Catheter Cardiovasc Interv 2013 1.40
20 Correlates of poor outcome among patients with bleeding after coronary interventions. Coron Artery Dis 2014 1.39
21 2-year clinical and angiographic outcomes from a randomized trial of polymer-free dual drug-eluting stents versus polymer-based Cypher and Endeavor [corrected] drug-eluting stents. J Am Coll Cardiol 2010 1.38
22 Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long-QT syndrome. EMBO J 2013 1.24
23 Essential myosin light chain as a target for caspase-3 in failing myocardium. Proc Natl Acad Sci U S A 2002 1.21
24 Abciximab and heparin versus bivalirudin for non-ST-elevation myocardial infarction. N Engl J Med 2011 1.20
25 Incidence and predictors of restenosis after coronary stenting in 10 004 patients with surveillance angiography. Heart 2013 1.19
26 Rationale and design of a randomised clinical trial comparing vascular closure device and manual compression to achieve haemostasis after diagnostic coronary angiography: the Instrumental Sealing of ARterial puncture site - CLOSURE device versus manual compression (ISAR-CLOSURE) trial. EuroIntervention 2014 1.16
27 Morphological assessment of renal arteries after radiofrequency catheter-based sympathetic denervation in a porcine model. J Hypertens 2012 1.12
28 Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes. EuroIntervention 2014 1.10
29 Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial. J Am Coll Cardiol 2011 1.07
30 Five-year clinical outcomes of sirolimus-eluting versus paclitaxel-eluting stents in high-risk patients. Catheter Cardiovasc Interv 2011 1.07
31 Erythropoietin in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a randomized, double-blind trial. Circ Cardiovasc Interv 2010 1.04
32 Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel. Proc Natl Acad Sci U S A 2012 1.03
33 Induced pluripotent stem cell-derived cardiomyocytes: a versatile tool for arrhythmia research. Circ Res 2013 1.03
34 Embryonic heart progenitors and cardiogenesis. Cold Spring Harb Perspect Med 2013 1.01
35 Pluripotent stem cell models of human heart disease. Cold Spring Harb Perspect Med 2013 1.01
36 Prognostic value of access and non-access sites bleeding after percutaneous coronary intervention. Circ Cardiovasc Interv 2013 0.96
37 Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-eluting Stents (ISAR-TEST 5) trial. Circulation 2011 0.95
38 Development. ES cells to the rescue. Science 2004 0.95
39 Zotarolimus- versus everolimus-eluting stents for unprotected left main coronary artery disease. J Am Coll Cardiol 2013 0.89
40 Multipotent progenitor cells in regenerative cardiovascular medicine. Pediatr Cardiol 2009 0.87
41 Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species. Stem Cells 2015 0.87
42 Impaired platelet function reduces myocardial infarct size in Galphaq knock-out mice in vivo. J Mol Cell Cardiol 2007 0.86
43 Everolimus-eluting versus sirolimus-eluting stents: a meta-analysis of randomized trials. Circ Cardiovasc Interv 2011 0.85
44 A potential life-threatening complication after implantation of a bioresorbable scaffold for coronary stenting within a mechanically stressed region. Clin Res Cardiol 2015 0.84
45 Very late stent thrombosis 42 months after implantation of sirolimus-eluting stent and discontinuation of antiplatelet therapy. Case Rep Med 2009 0.84
46 Direct nkx2-5 transcriptional repression of isl1 controls cardiomyocyte subtype identity. Stem Cells 2015 0.84
47 Incidence and impact on prognosis of bleeding during percutaneous coronary interventions in patients with chronic kidney disease. Clin Res Cardiol 2013 0.83
48 Simultaneous positron emission tomography/magnetic resonance imaging identifies sustained regional abnormalities in cardiac metabolism and function in stress-induced transient midventricular ballooning syndrome: a variant of Takotsubo cardiomyopathy. Circulation 2012 0.83
49 Bivalirudin versus heparin in patients treated with percutaneous coronary intervention: a meta-analysis of randomised trials. EuroIntervention 2015 0.83
50 Comparison of prasugrel and bivalirudin vs clopidogrel and heparin in patients with ST-segment elevation myocardial infarction: Design and rationale of the Bavarian Reperfusion Alternatives Evaluation (BRAVE) 4 trial. Clin Cardiol 2014 0.83
51 Modeling long-QT syndromes with iPS cells. J Cardiovasc Transl Res 2012 0.82
52 Selective attenuation of norepinephrine release and stress-induced heart rate increase by partial adenosine A1 agonism. PLoS One 2011 0.82
53 Randomized comparison of ticagrelor versus prasugrel in patients with acute coronary syndrome and planned invasive strategy--design and rationale of the iNtracoronary Stenting and Antithrombotic Regimen: Rapid Early Action for Coronary Treatment (ISAR-REACT) 5 trial. J Cardiovasc Transl Res 2013 0.82
54 Induced pluripotent stem cells in cardiovascular research. Rev Physiol Biochem Pharmacol 2012 0.81
55 Endovascular therapy for steno-occlusive subclavian and innominate artery disease. Circ J 2015 0.80
56 Five-year outcomes from a trial of three limus-eluting stents with different polymer coatings in patients with coronary artery disease: final results from the ISAR-TEST 4 randomised trial. EuroIntervention 2016 0.79
57 Radial artery applanation tonometry for continuous noninvasive arterial blood pressure monitoring in the cardiac intensive care unit. Clin Res Cardiol 2015 0.79
58 Liver laceration associated with the use of a chest compression device. Resuscitation 2009 0.78
59 Safety and efficacy of a potential treatment algorithm by using manual compression repair and ultrasound-guided thrombin injection for the management of iatrogenic femoral artery pseudoaneurysm in a large patient cohort. Circ Cardiovasc Interv 2014 0.78
60 Predictors of antiplatelet response to prasugrel during maintenance treatment. Platelets 2014 0.78
61 Bleeding after percutaneous coronary intervention with Bivalirudin or unfractionated Heparin and one-year mortality. Am J Cardiol 2009 0.78
62 Quantitative analysis of apoptotic markers in human end-stage heart failure. Eur J Heart Fail 2008 0.78
63 Microvascular obstruction in patients with non-ST-elevation myocardial infarction: a contrast-enhanced cardiac magnetic resonance study. Int J Cardiovasc Imaging 2014 0.77
64 Recapitulating long-QT syndrome using induced pluripotent stem cell technology. Pediatr Cardiol 2012 0.77
65 Mutational analysis of the human MESP1 gene in patients with congenital heart disease reveals a highly variable sequence in exon 1. Eur J Med Genet 2013 0.77
66 Massive thrombus burden with recurrence of intracoronary thrombosis early after stenting and delayed onset of prasugrel action in a patient with ST-elevation myocardial infarction and cardiac shock. Thromb Haemost 2011 0.77
67 Retroviral infection and selection of culture-derived platelets allows study of the effect of transgenes on platelet physiology ex vivo and on thrombus formation in vivo. Arterioscler Thromb Vasc Biol 2005 0.77
68 Association of increased CD8+ and persisting C-reactive protein levels with restenosis in HIV patients after coronary stenting. AIDS 2016 0.76
69 Negating the dominant-negative allele: a new treatment paradigm for arrhythmias explored in human induced pluripotent stem cell-derived cardiomyocytes. Eur Heart J 2013 0.75
70 Reply: Aspirin Treatment and Outcomes After Percutaneous Coronary Intervention: Results of the ISAR-ASPI Registry. J Am Coll Cardiol 2015 0.75
71 Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes. Eur Heart J 2017 0.75
72 MicroRNAs in a cardiac loop: progenitor or myocyte? Dev Cell 2010 0.75
73 Reply: Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug-Eluting Stent Implantation. J Am Coll Cardiol 2015 0.75
74 Reply: Duration of Triple Therapy: A Clinical Question Yet to Be Answered. J Am Coll Cardiol 2015 0.75
75 Safety and efficacy of different stent types for the endovascular therapy of extracranial vertebral artery disease. Clin Res Cardiol 2013 0.75
76 Angiographic and clinical outcomes of patients treated with drug-coated balloon angioplasty for in-stent restenosis after coronary bifurcation stenting with a two-stent technique. EuroIntervention 2016 0.75
77 Changes in high-sensitivity troponin after drug-coated balloon angioplasty for drug-eluting stent restenosis. EuroIntervention 2017 0.75
78 Unusual use of a standard percutaneous transluminal coronary angioplasty balloon catheter to the rescue. Eur Heart J 2008 0.75
79 Validation of the DAPT score in patients randomized to 6 or 12 months clopidogrel after predominantly second-generation drug-eluting stents. Thromb Haemost 2017 0.75
80 Renal failure after renal sympathetic ablation in a patient with chronic kidney disease--which came first, the chicken or the egg? Int J Cardiol 2013 0.75
81 Stem cell mobilisation by granulocyte-colony stimulating factor in patients with acute myocardial infarction. Long-term results of the REVIVAL-2 trial. Thromb Haemost 2016 0.75
82 How should I treat a complex left subclavian artery stenosis involving the vertebral artery in a patient with subclavian steal syndrome and left internal mammary artery bypass graft? EuroIntervention 2015 0.75
83 Genetic risk of restenosis after percutaneous coronary interventions in the era of drug-eluting stents. Coron Artery Dis 2014 0.75
84 Impact of stent size on angiographic and clinical outcomes after implantation of everolimus-eluting bioresorbable scaffolds in daily practice: insights from the ISAR-ABSORB registry. EuroIntervention 2016 0.75
85 Drug-eluting stents versus bare-metal stents for the prevention of restenosis in patients with renovascular disease. EuroIntervention 2017 0.75
86 Immature platelets as a novel biomarker for adverse cardiovascular events in patients after non-cardiac surgery. Thromb Haemost 2017 0.75
87 Endothelial RAGE exacerbates acute postischaemic cardiac inflammation. Thromb Haemost 2016 0.75
88 Outcomes of patients treated with durable-polymer platinum-chromium everolimus-eluting stents: a meta-analysis of randomized trials. EuroIntervention 2017 0.75
89 Impact of bivalirudin on post-procedural epicardial blood flow, risk of stent thrombosis and mortality after percutaneous coronary intervention. EuroIntervention 2016 0.75
90 Time does not heal all wounds: very late stent thrombosis eight years after implantation of a sirolimus-eluting stent due to positive remodelling, saccular evaginations and marked vascular inflammation. EuroIntervention 2013 0.75
91 Drug-coated balloon angioplasty for in-stent restenosis of femoropopliteal arteries. A meta-analysis. EuroIntervention 2017 0.75
92 Transcatheter aortic-valve endocarditis confirmed by transesophageal echocardiography. Circulation 2013 0.75
93 Bleeding after percutaneous coronary intervention in women and men matched for age, body mass index, and type of antithrombotic therapy. Am Heart J 2013 0.75