Patrick Descombes

Author PubWeight™ 75.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A whole-genome association study of major determinants for host control of HIV-1. Science 2007 15.19
2 Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology 2010 7.86
3 Common genetic variation and the control of HIV-1 in humans. PLoS Genet 2009 3.68
4 The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab 2006 3.00
5 RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization. BMC Genomics 2011 2.14
6 Decoding NMDA receptor signaling: identification of genomic programs specifying neuronal survival and death. Neuron 2007 2.08
7 Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals. PLoS Pathog 2010 1.90
8 Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension 2011 1.89
9 Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance. Am J Hum Genet 2007 1.86
10 Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development. Dev Biol 2005 1.85
11 Comparative transcriptomics of rice reveals an ancient pattern of response to microbial colonization. Proc Natl Acad Sci U S A 2005 1.74
12 Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity. PLoS Genet 2009 1.72
13 Genome-wide, high-resolution DNA methylation profiling using bisulfite-mediated cytosine conversion. Genome Res 2008 1.68
14 Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque. J Clin Invest 2011 1.61
15 ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir. Pharmacogenet Genomics 2010 1.46
16 Sertoli cell Dicer is essential for spermatogenesis in mice. Dev Biol 2008 1.37
17 Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAs. Chromosoma 2009 1.33
18 Expression profiling of mammalian male meiosis and gametogenesis identifies novel candidate genes for roles in the regulation of fertility. Mol Biol Cell 2004 1.33
19 Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function. Blood 2011 1.16
20 Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets. J Biol Chem 2004 1.14
21 MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation. BMC Bioinformatics 2006 1.11
22 Comparison of maize (Zea mays L.) F1-hybrid and parental inbred line primary root transcriptomes suggests organ-specific patterns of nonadditive gene expression and conserved expression trends. Genetics 2008 1.10
23 Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts. Br J Haematol 2008 1.09
24 Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism. Endocrinology 2007 1.05
25 Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor gamma. J Biol Chem 2007 1.03
26 Loss of Dicer in Sertoli cells has a major impact on the testicular proteome of mice. Mol Cell Proteomics 2010 1.01
27 No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model. Hum Mol Genet 2005 1.01
28 Orientation and expression of methicillin-resistant Staphylococcus aureus small RNAs by direct multiplexed measurements using the nCounter of NanoString technology. J Microbiol Methods 2010 1.00
29 Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research. Front Immunol 2012 0.97
30 Gene expression profiling provides insights into pathways of oxaliplatin-related sinusoidal obstruction syndrome in humans. Mol Cancer Ther 2011 0.95
31 Genome sequences of the high-acetic acid-resistant bacteria Gluconacetobacter europaeus LMG 18890T and G. europaeus LMG 18494 (reference strains), G. europaeus 5P3, and Gluconacetobacter oboediens 174Bp2 (isolated from vinegar). J Bacteriol 2011 0.92
32 Engineering of dominant active basic helix-loop-helix proteins that are resistant to negative regulation by postnatal central nervous system antineurogenic cues. Stem Cells 2009 0.91
33 Mutations in the SPARC-related modular calcium-binding protein 1 gene, SMOC1, cause waardenburg anophthalmia syndrome. Am J Hum Genet 2010 0.90
34 Global expression profiling of Chlamydomonas reinhardtii exposed to trace levels of free cadmium. Environ Toxicol Chem 2008 0.86
35 The cutaneous lesions of dioxin exposure: lessons from the poisoning of Victor Yushchenko. Toxicol Sci 2011 0.86
36 A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes. Genome Biol 2010 0.86
37 Potential detrimental effects of a phytoestrogen-rich diet on male fertility in mice. Mol Cell Endocrinol 2010 0.85
38 Using digital RNA counting and flow cytometry to compare mRNA with protein expression in acute leukemias. PLoS One 2012 0.83
39 Blockade of T cell contact-activation of human monocytes by high-density lipoproteins reveals a new pattern of cytokine and inflammatory genes. PLoS One 2010 0.82
40 Transcriptional and post-transcriptional profile of human chromosome 21. Genome Res 2009 0.78
41 Metabolism and biological activities of topical 4-oxoretinoids in mouse skin. J Invest Dermatol 2007 0.77
42 Extensive natural variation for cellular hydrogen peroxide release is genetically controlled. PLoS One 2012 0.77
43 Automatic analysis of microRNA microarray images using mathematical morphology. Conf Proc IEEE Eng Med Biol Soc 2007 0.75