Published in PLoS One on December 30, 2010
The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem (1994) 6.04
Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence. Biophys J (1990) 3.58
Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem (1996) 3.18
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic (2007) 3.01
Polymorphic phase behaviour of phospholipid membranes studied by infrared spectroscopy. Biochim Biophys Acta (1984) 2.92
Studies on the internalization mechanism of cationic cell-penetrating peptides. J Biol Chem (2003) 2.53
Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol Cell Neurosci (2004) 2.36
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells. J Am Chem Soc (2004) 2.33
Antennapedia homeobox peptide regulates neural morphogenesis. Proc Natl Acad Sci U S A (1991) 2.31
Break on through to the other side-biophysics and cell biology shed light on cell-penetrating peptides. Chembiochem (2005) 1.77
Coupled plasmon-waveguide resonators: a new spectroscopic tool for probing proteolipid film structure and properties. Biophys J (1997) 1.67
Lipid domains in bacterial membranes and the action of antimicrobial agents. Biochim Biophys Acta (2008) 1.58
Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery. Curr Opin Pharmacol (2006) 1.45
Thermodynamic studies and binding mechanisms of cell-penetrating peptides with lipids and glycosaminoglycans. Adv Drug Deliv Rev (2007) 1.43
Time-resolved fluorescence emission spectra of Laurdan in phospholipid vesicles by multifrequency phase and modulation fluorometry. Cell Mol Biol (1986) 1.41
The antennapedia peptide penetratin translocates across lipid bilayers - the first direct observation. FEBS Lett (2000) 1.40
Messenger proteins: homeoproteins, TAT and others. Curr Opin Cell Biol (2000) 1.38
Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential. Biochemistry (2003) 1.33
Effect of the N-terminal glycine on the secondary structure, orientation, and interaction of the influenza hemagglutinin fusion peptide with lipid bilayers. Biophys J (1996) 1.31
Charge-dependent translocation of the Trojan peptide penetratin across lipid membranes. Biophys J (2003) 1.28
Calorimetric and spectroscopic studies of the polymorphic phase behavior of a homologous series of n-saturated 1,2-diacyl phosphatidylethanolamines. Biophys J (1993) 1.22
Components of the carbonyl stretching band in the infrared spectra of hydrated 1,2-diacylglycerolipid bilayers: a reevaluation. Biophys J (1994) 1.21
Conformational states of the cell-penetrating peptide penetratin when interacting with phospholipid vesicles: effects of surface charge and peptide concentration. Biochim Biophys Acta (2002) 1.16
Tryptophan fluorescence study of the interaction of penetratin peptides with model membranes. Eur J Biochem (2002) 1.15
Insight into the mechanism of internalization of the cell-penetrating carrier peptide Pep-1 through conformational analysis. Biochemistry (2004) 1.14
Interaction and structure induction of cell-penetrating peptides in the presence of phospholipid vesicles. Biochim Biophys Acta (2001) 1.13
Influence of protein transduction domains on intracellular delivery of macromolecules. Expert Opin Drug Deliv (2006) 1.12
The product of rab2, a small GTP binding protein, increases neuronal adhesion, and neurite growth in vitro. Neuron (1990) 1.08
A model for the interaction of 6-lauroyl-2-(N,N-dimethylamino)naphthalene with lipid environments: implications for spectral properties. Photochem Photobiol (1999) 1.07
Non-metabolic membrane tubulation and permeability induced by bioactive peptides. PLoS One (2007) 1.07
Asymmetric insertion of membrane proteins in lipid bilayers by solid-state NMR paramagnetic relaxation enhancement: a cell-penetrating Peptide example. J Am Chem Soc (2008) 1.03
Membrane interactions of cell-penetrating peptides probed by tryptophan fluorescence and dichroism techniques: correlations of structure to cellular uptake. Biochemistry (2006) 1.01
Aggregation of cateslytin beta-sheets on negatively charged lipids promotes rigid membrane domains. A new mode of action for antimicrobial peptides? Biochemistry (2008) 1.01
Penetratin-induced aggregation and subsequent dissociation of negatively charged phospholipid vesicles. FEBS Lett (2001) 0.99
Plasmon-waveguide resonance and impedance spectroscopy studies of the interaction between penetratin and supported lipid bilayer membranes. Biophys J (2003) 0.98
Lipid reorganization induced by membrane-active peptides probed using differential scanning calorimetry. Biochim Biophys Acta (2009) 0.98
Interaction of the third helix of Antennapedia homeodomain and a phospholipid monolayer, studied by ellipsometry and PM-IRRAS at the air-water interface. Biochim Biophys Acta (2000) 0.96
Reversible sheet-turn conformational change of a cell-penetrating peptide in lipid bilayers studied by solid-state NMR. J Mol Biol (2008) 0.89
Antimicrobial and cytolytic activities and plausible mode of bactericidal action of the cell penetrating peptide penetratin and its lys-linked two-stranded peptide. Chem Biol Drug Des (2009) 0.88
Graphical analysis of mass and anisotropy changes observed by plasmon-waveguide resonance spectroscopy can provide useful insights into membrane protein function. Biophys J (2004) 0.87
The homeodomain derived peptide Penetratin induces curvature of fluid membrane domains. PLoS One (2008) 0.86
Energy-independent translocation of cell-penetrating peptides occurs without formation of pores. A biophysical study with pep-1. Mol Membr Biol (2007) 0.86
Rab3A and Rab3B carboxy-terminal peptides are both potent and specific inhibitors of prolactin release by rat cultured anterior pituitary cells. Mol Endocrinol (1994) 0.86
Vesicle membrane interactions of penetratin analogues. Biochemistry (2004) 0.86
The N-terminal domain of annexin 2 serves as a secondary binding site during membrane bridging. J Biol Chem (2008) 0.86
Modulation by Ca(2+) and by membrane binding of the dynamics of domain III of annexin 2 (p36) and the annexin 2-p11 complex (p90): implications for their biochemical properties. Biochemistry (2000) 0.84
Mitochondrial creatine kinase binding to phospholipids decreases fluidity of membranes and promotes new lipid-induced beta structures as monitored by red edge excitation shift, laurdan fluorescence, and FTIR. Biochemistry (2001) 0.83
Vesicle size-dependent translocation of penetratin analogs across lipid membranes. Biochim Biophys Acta (2004) 0.81
Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) II. Peptide conformation by infrared spectroscopy. Biophys Chem (2005) 0.81
Interactions of tryptophan-rich cathelicidin antimicrobial peptides with model membranes studied by differential scanning calorimetry. Biochim Biophys Acta (2007) 0.80
A molecular view on the interaction of the trojan peptide penetratin with the polar interface of lipid bilayers. Biophys J (2004) 0.80
Different molecular arrangements of the tetrameric annexin 2 modulate the size and dynamics of membrane aggregation. Biochim Biophys Acta (2010) 0.79
Interaction of the C-terminal region of the Ggamma protein with model membranes. Biophys J (2007) 0.79
The interaction of cell-penetrating peptides with lipid model systems and subsequent lipid reorganization: thermodynamic and structural characterization. J Pept Sci (2009) 0.79
Tubular structures in heterogeneous membranes induced by the cell penetrating peptide penetratin. Commun Integr Biol (2009) 0.78
Membrane-induced peptide structural changes monitored by infrared and circular dichroism spectroscopy. Biophys Chem (2009) 0.78
Acid-base studies with deuterium oxide. Ann N Y Acad Sci (1960) 0.77
Lipid domain separation, bilayer thickening and pearling induced by the cell penetrating peptide penetratin. Biochim Biophys Acta (2010) 0.77
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A (2008) 14.18
Proof of principle for transfusion of in vitro-generated red blood cells. Blood (2011) 3.01
Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases. Gut (2012) 2.17
Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J Biol Chem (2003) 2.02
Raft-mediated trafficking of apical resident proteins occurs in both direct and transcytotic pathways in polarized hepatic cells: role of distinct lipid microdomains. Mol Biol Cell (2003) 1.46
Sera from patients with Crohn's disease break bacterial lipopolysaccharide tolerance of human intestinal epithelial cells via MD-2 activity. Innate Immun (2010) 1.43
Annexin 2 binding to phosphatidylinositol 4,5-bisphosphate on endocytic vesicles is regulated by the stress response pathway. J Biol Chem (2004) 1.32
Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex. J Am Soc Nephrol (2005) 1.15
Detergents induce raft-like domains budding and fission from giant unilamellar heterogeneous vesicles: a direct microscopy observation. Chem Phys Lipids (2005) 1.14
Rafts promote assembly and atypical targeting of a nonenveloped virus, rotavirus, in Caco-2 cells. J Virol (2002) 1.14
The timing of pigmentation lightening in Europeans. Mol Biol Evol (2012) 1.13
New paradigms and tools in drug design for pain and addiction. AAPS J (2006) 1.07
Cyclooxygenase-2 and its role in colorectal cancer development. Virchows Arch (2004) 1.07
Non-metabolic membrane tubulation and permeability induced by bioactive peptides. PLoS One (2007) 1.07
Vimentin affects localization and activity of sodium-glucose cotransporter SGLT1 in membrane rafts. J Cell Sci (2002) 1.05
Galectin-4-regulated delivery of glycoproteins to the brush border membrane of enterocyte-like cells. Traffic (2009) 1.05
Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative. Biochem J (2004) 1.04
Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers. J Am Chem Soc (2005) 1.03
Rotavirus spike protein VP4 binds to and remodels actin bundles of the epithelial brush border into actin bodies. J Virol (2006) 0.99
Spike protein VP4 assembly with maturing rotavirus requires a postendoplasmic reticulum event in polarized caco-2 cells. J Virol (2004) 0.98
Basolateral internalization of GPI-anchored proteins occurs via a clathrin-independent flotillin-dependent pathway in polarized hepatic cells. Mol Biol Cell (2009) 0.98
Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II. BMC Biochem (2003) 0.97
Expression of nonstructural rotavirus protein NSP4 mimics Ca2+ homeostasis changes induced by rotavirus infection in cultured cells. J Virol (2008) 0.95
Current smoking differentially affects blood mononuclear cells from patients with Crohn's disease and ulcerative colitis: relevance to its adverse role in the disease. Inflamm Bowel Dis (2011) 0.95
Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain. J Virol (2006) 0.93
Glycan-modifying bacteria-derived soluble factors from Bacteroides thetaiotaomicron and Lactobacillus casei inhibit rotavirus infection in human intestinal cells. Microbes Infect (2011) 0.91
Dipyridamole enhances digoxin bioavailability via P-glycoprotein inhibition. Clin Pharmacol Ther (2003) 0.90
Interactions of rotavirus VP4 spike protein with the endosomal protein Rab5 and the prenylated Rab acceptor PRA1. J Virol (2003) 0.89
Annexin 2 "secretion" accompanying exocytosis of chromaffin cells: possible mechanisms of annexin release. Exp Cell Res (2002) 0.88
MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells. Life Sci (2007) 0.88
Novel organization and properties of annexin 2-membrane complexes. J Biol Chem (2003) 0.87
Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production. Cancer Lett (2006) 0.87
Host-pathogens cross-talk. Indigenous bacteria and probiotics also play the game. Biol Cell (2003) 0.87
The homeodomain derived peptide Penetratin induces curvature of fluid membrane domains. PLoS One (2008) 0.86
Cytoplasmic phospholipase A2 alpha overexpression in stromal cells is correlated with angiogenesis in human colorectal cancer. Mod Pathol (2005) 0.86
Differential solubilization of inner plasma membrane leaflet components by Lubrol WX and Triton X-100. Biochim Biophys Acta (2007) 0.86
Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.86
The N-terminal domain of annexin 2 serves as a secondary binding site during membrane bridging. J Biol Chem (2008) 0.86
1-benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside blocks the apical biosynthetic pathway in polarized HT-29 cells. J Biol Chem (2003) 0.85
Role for actin in the polarized release of rotavirus. J Virol (2007) 0.85
Cytosolic phospholipase A2-p11 interaction controls arachidonic acid release as a function of epithelial cell confluence. Biochem J (2004) 0.84
COX-2, inflammatory secreted PLA2, and cytoplasmic PLA2 protein expression in small bowel adenocarcinomas compared with colorectal adenocarcinomas. Mod Pathol (2003) 0.84
Surface proteome analysis of a natural isolate of Lactococcus lactis reveals the presence of pili able to bind human intestinal epithelial cells. Mol Cell Proteomics (2013) 0.84
Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells. PLoS One (2009) 0.83
Heterogeneity of Raft-type membrane microdomains associated with VP4, the rotavirus spike protein, in Caco-2 and MA 104 cells. J Virol (2006) 0.83
Recruitment and membrane interactions of host cell proteins during attachment of enteropathogenic and enterohaemorrhagic Escherichia coli. Biochem J (2012) 0.83
Microbial-host interactions specifically control the glycosylation pattern in intestinal mouse mucosa. Histochem Cell Biol (2002) 0.83
[Transduction peptides: structural-functional analyses in model membranes]. J Soc Biol (2006) 0.82
Regulation of colon cancer cell proliferation and migration by MD-2 activity. Innate Immun (2010) 0.81
Mucinous colon carcinomas with microsatellite instability have a lower microvessel density and lower vascular endothelial growth factor expression. Virchows Arch (2002) 0.80
HDLs induce raft domain vanishing in heterogeneous giant vesicles. Chem Phys Lipids (2004) 0.80
Indigenous microbes and their soluble factors differentially modulate intestinal glycosylation steps in vivo. Use of a "lectin assay" to survey in vivo glycosylation changes. Histochem Cell Biol (2005) 0.80
Different molecular arrangements of the tetrameric annexin 2 modulate the size and dynamics of membrane aggregation. Biochim Biophys Acta (2010) 0.79
Use of plasmon waveguide resonance (PWR) spectroscopy for examining binding, signaling and lipid domain partitioning of membrane proteins. Life Sci (2009) 0.79
Lipid organization regulates annexin A2 Ca(2+)-sensitivity for membrane bridging and its modulator effects on membrane fluidity. Biochim Biophys Acta (2012) 0.79
Modulation of the phase heterogeneity of aminoglycerophospholipid mixtures by sphingomyelin and monovalent cations: maintenance of the lamellar arrangement in the biological membranes. Eur Biophys J (2004) 0.79
Effects of dairy products on heterocyclic aromatic amine-induced rat colon carcinogenesis. Carcinogenesis (2002) 0.78
Abnormal transbilayer distribution of phospholipids in red blood cell membranes in schizophrenia. Psychiatry Res (2009) 0.78
Tubular structures in heterogeneous membranes induced by the cell penetrating peptide penetratin. Commun Integr Biol (2009) 0.78
Caspase-8 binding to cardiolipin in giant unilamellar vesicles provides a functional docking platform for bid. PLoS One (2013) 0.78
Metabolic energy-independent mechanism of internalization for the cell penetrating peptide penetratin. Int J Biochem Cell Biol (2012) 0.78
Lipid domain separation, bilayer thickening and pearling induced by the cell penetrating peptide penetratin. Biochim Biophys Acta (2010) 0.77
Managing Alcohol Problems in General Practice in Europe: Results from the European ODHIN Survey of General Practitioners. Alcohol Alcohol (2016) 0.77
Chapter 6. Plasmon resonance methods in membrane protein biology applications to GPCR signaling. Methods Enzymol (2009) 0.77
Arsenic trioxide reduces 2,4,6-trinitrobenzene sulfonic acid-induced murine colitis via nuclear factor-κB down-regulation and caspase-3 activation. Innate Immun (2010) 0.77
Enteric nervous system impairment in gastroschisis. Eur J Pediatr Surg (2012) 0.76
Liquid-liquid immiscibility under non-equilibrium conditions in a model membrane: an X-ray synchrotron study. Colloids Surf B Biointerfaces (2009) 0.76
Rotavirus-like particles: a novel nanocarrier for the gut. J Biomed Biotechnol (2010) 0.76
Differential detergent resistance of the apical and basolateral NPPases: relationship with polarized targeting. J Cell Sci (2007) 0.76
[Mechanisms of sorting and transport of proteins to tw membrane domains of epithelial cells]. J Soc Biol (2003) 0.76
A yeast toxic mutant of HET-s amyloid disrupts membrane integrity. Biochim Biophys Acta (2012) 0.75
High-resolution mass spectrometry and partial de novo sequencing constitute a useful approach for determining the profile of chemokine secretion following the stimulation of human intestinal epithelial cells. Rapid Commun Mass Spectrom (2013) 0.75
Endoscopic gastric band removal: safe and effective alternative to surgery. Dig Endosc (2014) 0.75