PubRank

Joseph A Califano

Author PubWeight™ 156.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011 11.12
2 TP53 mutations and survival in squamous-cell carcinoma of the head and neck. N Engl J Med 2007 5.92
3 BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab 2005 4.39
4 Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer 2005 3.27
5 Alcohol consumption and expenditures for underage drinking and adult excessive drinking. JAMA 2003 2.59
6 MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer 2008 2.56
7 Impact of pharyngeal closure technique on fistula after salvage laryngectomy. JAMA Otolaryngol Head Neck Surg 2013 2.37
8 Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. J Biol Chem 2008 2.07
9 DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. Int J Cancer 2007 1.97
10 Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. Clin Cancer Res 2002 1.97
11 Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon. Head Neck 2008 1.97
12 Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing. Cancer Res 2004 1.74
13 Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc Natl Acad Sci U S A 2007 1.68
14 Consensus statement on the classification and terminology of neck dissection. Arch Otolaryngol Head Neck Surg 2008 1.68
15 Endothelin receptor type B gene promoter hypermethylation in salivary rinses is independently associated with risk of oral cavity cancer and premalignancy. Cancer Prev Res (Phila) 2010 1.68
16 Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma. Clin Cancer Res 2008 1.62
17 Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer. Clin Cancer Res 2007 1.62
18 Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma. Lancet Oncol 2006 1.61
19 The molecular biology of mucosal field cancerization of the head and neck. Crit Rev Oral Biol Med 2003 1.58
20 Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer. Int J Cancer 2006 1.56
21 Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission. Int J Cancer 2010 1.53
22 Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res 2002 1.53
23 DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res 2005 1.44
24 Serum microRNA biomarkers for detection of non-small cell lung cancer. PLoS One 2012 1.43
25 Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions. Clin Cancer Res 2004 1.37
26 The role of human papillomavirus in oral carcinogenesis. Crit Rev Oral Biol Med 2004 1.31
27 Presence of HPV DNA in convalescent salivary rinses is an adverse prognostic marker in head and neck squamous cell carcinoma. Oral Oncol 2008 1.29
28 TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Clin Cancer Res 2010 1.27
29 Identification of hypermethylated genes associated with cisplatin resistance in human cancers. Cancer Res 2010 1.26
30 KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses. Int J Cancer 2010 1.26
31 Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. Clin Cancer Res 2009 1.24
32 Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation. Cancer Lett 2008 1.23
33 Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma. Cancer Res 2006 1.22
34 Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing. Cancer Res 2003 1.20
35 Value of chest CT in the diagnosis and management of tracheobronchial foreign bodies. Pediatr Int 2011 1.16
36 Activation of the NOTCH pathway in head and neck cancer. Cancer Res 2013 1.15
37 Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC. PLoS One 2009 1.14
38 An epigenetic marker panel for detection of lung cancer using cell-free serum DNA. Clin Cancer Res 2011 1.13
39 Promoter methylation in head and neck squamous cell carcinoma cell lines is significantly different than methylation in primary tumors and xenografts. PLoS One 2011 1.12
40 p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma. Oral Oncol 2010 1.10
41 Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma. Clin Cancer Res 2011 1.09
42 A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma. Int J Cancer 2011 1.08
43 Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer. Mol Cancer 2006 1.08
44 Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer. Cancer Res 2006 1.07
45 A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: creation and rationale for inclusion of tumor (T) characteristics. J Am Acad Dermatol 2011 1.06
46 Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer. Biochem Biophys Res Commun 2008 1.05
47 Identification of genes differentially expressed in benign versus malignant thyroid tumors. Clin Cancer Res 2008 1.05
48 Molecular pathology of head-and-neck cancer. Int J Cancer 2004 1.05
49 Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance. Clin Cancer Res 2011 1.04
50 Intraoperative molecular margin analysis in head and neck cancer. Arch Otolaryngol Head Neck Surg 2004 1.04
51 Advances and Perspectives in the Molecular Diagnosis of Head and Neck Cancer. Expert Opin Med Diagn 2010 1.03
52 Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects. J Natl Cancer Inst 2003 1.03
53 Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. Cancer Prev Res (Phila) 2010 1.03
54 The gastrointestinal manifestations of telomere-mediated disease. Aging Cell 2013 1.00
55 Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer. Lung Cancer 2006 1.00
56 Recurrence patterns and management of oral cavity premalignant lesions. Oral Oncol 2013 1.00
57 EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions. Clin Cancer Res 2013 0.99
58 DCC promoter hypermethylation in esophageal squamous cell carcinoma. Int J Cancer 2008 0.98
59 Detection of TIMP3 promoter hypermethylation in salivary rinse as an independent predictor of local recurrence-free survival in head and neck cancer. Clin Cancer Res 2012 0.97
60 Applying the molecular biology and epigenetics of head and neck cancer in everyday clinical practice. Oral Oncol 2008 0.97
61 Molecular techniques and genetic alterations in head and neck cancer. Oral Oncol 2008 0.96
62 Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma. PLoS One 2012 0.96
63 Vitamin E succinate induces ceramide-mediated apoptosis in head and neck squamous cell carcinoma in vitro and in vivo. Clin Cancer Res 2008 0.96
64 Decreased mitochondrial DNA content in posttreatment salivary rinses from head and neck cancer patients. Clin Cancer Res 2006 0.96
65 Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients. Cancer Prev Res (Phila) 2010 0.95
66 Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors. PLoS One 2010 0.95
67 The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical Margins. Clin Cancer Res 2009 0.95
68 Estimate of the commercial value of underage drinking and adult abusive and dependent drinking to the alcohol industry. Arch Pediatr Adolesc Med 2006 0.95
69 The role of pre-operative CT-guided FNAB for parapharyngeal space tumors. Otolaryngol Head Neck Surg 2007 0.94
70 Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma. Int J Cancer 2011 0.93
71 BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer. Clin Cancer Res 2011 0.93
72 Promoter hypermethylation in Indian primary oral squamous cell carcinoma. Int J Cancer 2010 0.92
73 Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity. Head Neck 2004 0.91
74 ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer. Clin Cancer Res 2008 0.91
75 Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy. Mol Cancer Ther 2012 0.90
76 Neck management in patients undergoing postradiotherapy salvage laryngeal surgery for recurrent/persistent laryngeal cancer. Laryngoscope 2006 0.90
77 Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors. Clin Cancer Res 2004 0.90
78 Transoral robotic surgery experience in 44 cases. J Laparoendosc Adv Surg Tech A 2013 0.89
79 Progression of microsatellite instability from premalignant lesions to tumors of the head and neck. Int J Cancer 2002 0.89
80 Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma. Head Neck 2011 0.89
81 Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma. Oral Oncol 2011 0.89
82 Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling. Cancer Invest 2011 0.89
83 Death-associated protein kinase promoter hypermethylation in normal human lymphocytes. Cancer Res 2003 0.88
84 Mitochondrial DNA alterations in thyroid cancer. J Surg Oncol 2003 0.88
85 EIF2C is overexpressed and amplified in head and neck squamous cell carcinoma. ORL J Otorhinolaryngol Relat Spec 2010 0.87
86 Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer. Clin Cancer Res 2007 0.87
87 Colorimetric approach to high-throughput mutation analysis. Biotechniques 2005 0.87
88 Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PLoS One 2009 0.87
89 Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction. Laryngoscope 2004 0.87
90 Supracricoid laryngectomy outcomes: The Johns Hopkins experience. Laryngoscope 2007 0.86
91 Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO. Oral Oncol 2005 0.86
92 Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers. ORL J Otorhinolaryngol Relat Spec 2010 0.85
93 Short hospital stay after neck dissection. Otolaryngol Head Neck Surg 2005 0.85
94 Transoral robotic surgery of the vocal cord. J Laparoendosc Adv Surg Tech A 2011 0.84
95 Dose-dependent activation of putative oncogene SBSN by BORIS. PLoS One 2012 0.84
96 MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma. PLoS One 2012 0.84
97 Novel integrative methods for gene discovery associated with head and neck squamous cell carcinoma development. Arch Otolaryngol Head Neck Surg 2009 0.84
98 Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma. Int J Cancer 2003 0.83
99 Sequencing the head and neck cancer genome: implications for therapy. Ann N Y Acad Sci 2014 0.83
100 Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1α stabilization. PLoS One 2011 0.83
101 Preferential activation of the hedgehog pathway by epigenetic modulations in HPV negative HNSCC identified with meta-pathway analysis. PLoS One 2013 0.83
102 Tissue imprint for molecular mapping of deep surgical margins in patients with head and neck squamous cell carcinoma. Head Neck 2012 0.83
103 A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma. Clin Cancer Res 2007 0.82
104 Neck dissection followed by radiotherapy or chemoradiotherapy for small primary oropharynx carcinoma with cervical metastasis. Laryngoscope 2005 0.82
105 Chronic cigarette smoke extract treatment selects for apoptotic dysfunction and mitochondrial mutations in minimally transformed oral keratinocytes. Int J Cancer 2010 0.82
106 Promoter methylation and loss of p16(INK4a) gene expression in head and neck cancer. Head Neck 2011 0.82
107 Prescription medication abuse and illegitimate internet-based pharmacies. Ann Intern Med 2011 0.81
108 Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling. Int J Oncol 2013 0.81
109 The molecular biology of laryngeal cancer. Otolaryngol Clin North Am 2002 0.81
110 Detectable BRAF mutation in serum DNA samples from patients with papillary thyroid carcinomas. Head Neck 2010 0.81
111 Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome. Genomics 2010 0.81
112 Robotic-assisted neck dissection through a pre- and post-auricular hairline incision: preclinical study. J Laparoendosc Adv Surg Tech A 2012 0.80
113 Neck dissection through a facelift incision. Laryngoscope 2012 0.80
114 Silencing of high-mobility group box 2 (HMGB2) modulates cisplatin and 5-fluorouracil sensitivity in head and neck squamous cell carcinoma. Proteomics 2015 0.80
115 Alterations of GPI transamidase subunits in head and neck squamous carcinoma. Mol Cancer 2007 0.80
116 Comparison of acute toxicities in two primary chemoradiation regimens in the treatment of advanced head and neck squamous cell carcinoma. Ann Surg Oncol 2012 0.80
117 Severe hypocalcemia complicating thyroid surgery after Roux-en-Y gastric bypass procedure. Arch Otolaryngol Head Neck Surg 2009 0.80
118 Nonsynonymous somatic mitochondrial mutations occur in the majority of cutaneous melanomas. Melanoma Res 2008 0.79
119 Correcting transcription factor gene sets for copy number and promoter methylation variations. Drug Dev Res 2014 0.79
120 MAGEA4 induces growth in normal oral keratinocytes by inhibiting growth arrest and apoptosis. Oncol Rep 2012 0.79
121 The role of MAGEA2 in head and neck cancer. Arch Otolaryngol Head Neck Surg 2011 0.77
122 Multidisciplinary service utilization pattern by advanced head and neck cancer patients: a single institution study. Int J Otolaryngol 2012 0.77
123 The epidermal growth factor receptor axis: support for a new target for oral premalignancy. Cancer Prev Res (Phila) 2010 0.77
124 The effect of amifostine on submandibular gland histology after radiation. Int J Otolaryngol 2012 0.77
125 Comparison of promoter hypermethylation pattern in salivary rinses collected with and without an exfoliating brush from patients with HNSCC. PLoS One 2012 0.76
126 p53 mutation is rare in oral mucosa brushings from patients previously treated for a head and neck squamous cell carcinoma. Oral Oncol 2008 0.76
127 Reluctance to undergo follow-up screening for head and neck cancer is associated with income, gender, and tobacco use. ORL J Otorhinolaryngol Relat Spec 2010 0.76
128 Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma. Melanoma Res 2011 0.76
129 mTOR inhibition prevents rapid-onset of carcinogen-induced malignancies in a novel inducible HPV-16 E6/E7 mouse model. Carcinogenesis 2016 0.76
130 Hyperfractionated radiotherapy with concurrent cisplatin/5-Fluorouracil for locoregional advanced head and neck cancer: analysis of 105 consecutive patients. Int J Otolaryngol 2012 0.75
131 The infighting over abortion: an administration divided. Washington Post 1981 0.75
132 Califano and abortion: questions of conscience. Washington Post 1981 0.75
133 Rationing health care: the unnecessary solution. Univ PA Law Rev 1992 0.75
134 Corrigendum: A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma. Sci Rep 2017 0.75
135 Radiology quiz case 1. Benign parotid cyst with associated facial paralysis. Arch Otolaryngol Head Neck Surg 2005 0.75
136 The dangers of discovery. America (NY) 1995 0.75
137 Sterilization. Forum (Wash) 1978 0.75
138 Moral leadership and partisanship. America (NY) 1984 0.75
139 Conservative management of transnasal intracranial injury. Am J Otolaryngol 2010 0.75
140 Physician-assisted living. America (NY) 1998 0.75
141 Evaluation of prophylaxis treatment of Candida in alaryngeal patients with tracheoesophageal voice prostheses. Laryngoscope 2014 0.75