Published in Acta Neuropathol on January 26, 2011
Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol (2011) 6.67
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol (2012) 3.88
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet (2013) 3.19
Medulloblastomics: the end of the beginning. Nat Rev Cancer (2012) 3.01
The Hedgehog's tale: developing strategies for targeting cancer. Nat Rev Cancer (2011) 2.60
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell (2014) 2.57
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathol (2011) 2.53
Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell (2012) 2.45
A mouse model of the most aggressive subgroup of human medulloblastoma. Cancer Cell (2012) 2.15
The clinical implications of medulloblastoma subgroups. Nat Rev Neurol (2012) 2.12
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update. Nat Rev Clin Oncol (2015) 2.02
Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032. J Clin Oncol (2015) 1.72
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev (2012) 1.64
Cytogenetic prognostication within medulloblastoma subgroups. J Clin Oncol (2014) 1.56
Diffuse intrinsic pontine tumors: a study of primitive neuroectodermal tumors versus the more common diffuse intrinsic pontine gliomas. J Neurosurg Pediatr (2012) 1.50
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. J Clin Oncol (2013) 1.43
Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma. Neuro Oncol (2012) 1.30
DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta Neuropathol (2013) 1.27
Phase I study of vismodegib in children with recurrent or refractory medulloblastoma: a pediatric brain tumor consortium study. Clin Cancer Res (2013) 1.20
Distinct disease-risk groups in pediatric supratentorial and posterior fossa ependymomas. Acta Neuropathol (2012) 1.16
Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group. Acta Neuropathol (2013) 1.12
Risk stratification of childhood medulloblastoma in the molecular era: the current consensus. Acta Neuropathol (2016) 1.11
The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants. Oncogene (2014) 1.11
Role of MYC in Medulloblastoma. Cold Spring Harb Perspect Med (2013) 1.10
Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth. J Neuropathol Exp Neurol (2011) 1.10
CXCR4 activation defines a new subgroup of Sonic hedgehog-driven medulloblastoma. Cancer Res (2011) 1.09
Molecular subgroups of medulloblastoma. Expert Rev Neurother (2012) 1.05
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma. Nat Genet (2016) 1.05
MRI surrogates for molecular subgroups of medulloblastoma. AJNR Am J Neuroradiol (2014) 1.04
Molecular insights into pediatric brain tumors have the potential to transform therapy. Clin Cancer Res (2014) 0.96
The molecular classification of medulloblastoma: driving the next generation clinical trials. Curr Opin Pediatr (2012) 0.94
The rationale for targeted therapies in medulloblastoma. Neuro Oncol (2013) 0.92
Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. Cell Rep (2015) 0.92
A neuropathology-based approach to epilepsy surgery in brain tumors and proposal for a new terminology use for long-term epilepsy-associated brain tumors. Acta Neuropathol (2014) 0.91
Clinical neuropathology practice guide 3-2013: levels of evidence and clinical utility of prognostic and predictive candidate brain tumor biomarkers. Clin Neuropathol (2013) 0.90
Consensus Paper: Cerebellar Development. Cerebellum (2016) 0.89
WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma. Oncogene (2016) 0.87
Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation. Cancer Lett (2013) 0.85
Pediatric medulloblastoma - update on molecular classification driving targeted therapies. Front Oncol (2014) 0.85
Medulloblastoma in China: clinicopathologic analyses of SHH, WNT, and non-SHH/WNT molecular subgroups reveal different therapeutic responses to adjuvant chemotherapy. PLoS One (2014) 0.85
Molecular and cellular pathogenesis of adamantinomatous craniopharyngioma. Neuropathol Appl Neurobiol (2015) 0.84
Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement. Neuro Oncol (2012) 0.84
MicroRNA Regulation of Brain Tumour Initiating Cells in Central Nervous System Tumours. Stem Cells Int (2015) 0.82
Molecular subgroups of adult medulloblastoma: a long-term single-institution study. Neuro Oncol (2016) 0.81
Signaling pathway and molecular subgroups of medulloblastoma. Int J Clin Exp Pathol (2013) 0.81
What underlies the diversity of brain tumors? Cancer Metastasis Rev (2013) 0.81
Overcoming multiple drug resistance mechanisms in medulloblastoma. Acta Neuropathol Commun (2014) 0.81
Management of pediatric and adult patients with medulloblastoma. Curr Treat Options Oncol (2014) 0.80
Isochromosome 17q, MYC amplification and large cell/anaplastic phenotype in a case of medullomyoblastoma with extracranial metastases. Pediatr Blood Cancer (2011) 0.80
Update on molecular and genetic alterations in adult medulloblastoma. Memo (2012) 0.80
Biologically targeted therapeutics in pediatric brain tumors. Pediatr Neurol (2012) 0.80
Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial. Oncotarget (2015) 0.80
Myc proteins in brain tumor development and maintenance. Ups J Med Sci (2012) 0.80
WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathol Commun (2014) 0.79
G-protein coupled receptor expression patterns delineate medulloblastoma subgroups. Acta Neuropathol Commun (2013) 0.79
Signals that regulate the oncogenic fate of neural stem cells and progenitors. Exp Neurol (2013) 0.79
The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs). Br J Cancer (2013) 0.79
Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma. Cancer Lett (2014) 0.79
Molecular Classification of Medulloblastoma. Neurol Med Chir (Tokyo) (2016) 0.79
Radiotherapy for adult medulloblastoma: Long term result from a single institution. A review of prognostic factors and why we do need a multi-institutional cooperative program. Rep Pract Oncol Radiother (2015) 0.78
Gorlin syndrome and desmoplastic medulloblastoma: Report of 3 cases with unfavorable clinical course and novel mutations. Pediatr Blood Cancer (2015) 0.77
Improved health-related quality of life outcomes associated with SHH subgroup medulloblastoma in SIOP-UKCCSG PNET3 trial survivors. Acta Neuropathol (2014) 0.77
Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice. Development (2015) 0.77
Genome-wide network analysis of Wnt signaling in three pediatric cancers. Sci Rep (2013) 0.77
Factors affecting survival of medulloblastoma in children: the changing concept of management. Childs Nerv Syst (2015) 0.77
Computer-assisted quantification of motile and invasive capabilities of cancer cells. Sci Rep (2015) 0.77
Effect of small nuclear ribonucleoprotein-associated polypeptide N on the proliferation of medulloblastoma cells. Mol Med Rep (2015) 0.77
MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown. J Hematol Oncol (2015) 0.77
Contrast enhancement pattern predicts poor survival for patients with non-WNT/SHH medulloblastoma tumours. J Neurooncol (2015) 0.76
Update on the integrated histopathological and genetic classification of medulloblastoma - a practical diagnostic guideline. Clin Neuropathol (2016) 0.76
Wnt pathway in atypical teratoid rhabdoid tumors. Neuro Oncol (2014) 0.76
A microRNA-1280/JAG2 network comprises a novel biological target in high-risk medulloblastoma. Oncotarget (2015) 0.76
Genetic grouping of medulloblastomas by representative markers in pathologic diagnosis. Transl Oncol (2013) 0.76
Advances in paediatric cancer treatment. Transl Pediatr (2014) 0.76
The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies. BMC Cancer (2017) 0.75
Neuroradiology and histopathology in two cases of adult medulloblastoma. Neuroradiol J (2014) 0.75
Restore the brake on tumor progression. Biochem Pharmacol (2017) 0.75
Adult medulloblastoma: A rare case report and literature review. Surg Neurol Int (2016) 0.75
Gene expression by simian virus 40 large T antigen-induced medulloblastomas in mice. Neural Regen Res (2012) 0.75
Integrated Proteomic and Transcriptomic-Based Approaches to Identifying Signature Biomarkers and Pathways for Elucidation of Daoy and UW228 Subtypes. Proteomes (2017) 0.75
Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups. PLoS One (2017) 0.75
MR Imaging Characteristics of Wingless-Type-Subgroup Pediatric Medulloblastoma. AJNR Am J Neuroradiol (2015) 0.75
SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling. Nutrients (2016) 0.75
Medulloblastoma: Molecular Classification-Based Personal Therapeutics. Neurotherapeutics (2017) 0.75
Analysis of chromosome 17 miRNAs and their importance in medulloblastomas. Biomed Res Int (2015) 0.75
Clinical, pathological, and molecular data on desmoplastic/nodular medulloblastoma: case studies and a review of the literature. Clin Neuropathol (2016) 0.75
Anomalous vascularization in a Wnt medulloblastoma: a case report. BMC Neurol (2016) 0.75
Pediatric neurosurgery-science, art, and humility: reflection of personal experience. Childs Nerv Syst (2013) 0.75
Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic Pathway. Cancer Res (2016) 0.75
An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis. Neurosurg Rev (2014) 0.75
Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors. Oncotarget (2017) 0.75
Large cell/anaplastic medulloblastoma is associated with poor prognosis-a retrospective analysis at a single institute. Childs Nerv Syst (2017) 0.75
Molecular Testing of Brain Tumor. J Pathol Transl Med (2017) 0.75
Embryonal tumors in Canadian children less than 36 months of age: results from the Canadian Pediatric Brain Tumor Consortium (CPBTC). J Neurooncol (2017) 0.75
Risk factors for the prognosis of pediatric medulloblastoma: a retrospective analysis of 40 cases. Clinics (Sao Paulo) (2017) 0.75
The kinesin KIF14 is overexpressed in medulloblastoma and downregulation of KIF14 suppressed tumor proliferation and induced apoptosis. Lab Invest (2017) 0.75
Altered neural cell fates and medulloblastoma in mouse patched mutants. Science (1997) 11.44
Medulloblastoma comprises four distinct molecular variants. J Clin Oncol (2010) 8.06
Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. N Engl J Med (2009) 7.23
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol (2006) 5.96
Subtypes of medulloblastoma have distinct developmental origins. Nature (2010) 5.94
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One (2008) 5.86
Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med (2005) 5.81
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol (2010) 4.48
Mutations in SUFU predispose to medulloblastoma. Nat Genet (2002) 3.78
The origins of medulloblastoma subtypes. Annu Rev Pathol (2008) 3.36
Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched. Cancer Res (2001) 3.30
Sporadic medulloblastomas contain PTCH mutations. Cancer Res (1997) 3.22
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J Clin Oncol (2009) 3.01
beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee. J Clin Oncol (2005) 2.84
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev (2009) 2.58
Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res (1997) 2.45
Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure. Cancer Cell (2008) 2.42
Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res (1998) 2.41
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis. Cell Cycle (2006) 2.37
Sporadic medulloblastomas contain oncogenic beta-catenin mutations. Cancer Res (1998) 2.33
Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics. J Pathol (2009) 2.15
Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clin Oncol (2010) 2.04
Filamins in cell signaling, transcription and organ development. Trends Cell Biol (2010) 1.99
The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br J Cancer (1991) 1.94
Medulloblastoma with extensive nodularity: a variant with favorable prognosis. J Neurosurg (1999) 1.87
Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. Blood (1999) 1.83
Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops. J Biol Chem (2006) 1.75
Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients. Clin Cancer Res (2004) 1.67
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas. Cancer Res (2001) 1.60
Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behavior. Brain Pathol (2007) 1.59
Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells. Cancer Res (2010) 1.55
Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis. J Clin Oncol (2010) 1.48
APC mutations in sporadic medulloblastomas. Am J Pathol (2000) 1.40
Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma. Genes Chromosomes Cancer (2000) 1.36
The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials. Br J Neurosurg (2009) 1.27
Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors. Int J Cancer (2001) 1.23
Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours. Oncogene (1997) 1.23
Childhood medulloblastoma: novel approaches to the classification of a heterogeneous disease. Acta Neuropathol (2010) 1.15
Large-cell medulloblastomas. A distinct variant with highly aggressive behavior. Am J Surg Pathol (1992) 1.08
Mutations of the Wnt antagonist AXIN2 (Conductin) result in TCF-dependent transcription in medulloblastomas. Int J Cancer (2007) 1.03
Filamin A mutation, a common cause for periventricular heterotopia, aneurysms and cardiac defects. J Neurol Neurosurg Psychiatry (2009) 1.01
Epidemiology of adult medulloblastoma. Int J Cancer (1999) 0.98
Identification of PATCHED mutations in medulloblastomas by direct sequencing. Hum Mutat (2000) 0.97
Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma. Acta Neuropathol (2010) 0.97
Risk stratification of medulloblastoma: a paradigm for future childhood brain tumor management strategies. Curr Neurol Neurosci Rep (2011) 0.88
Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression. Oncogene (2003) 0.87
The hedgehog pathway inhibitor GDC-0449 shows potential in skin and other cancers. Expert Opin Investig Drugs (2010) 0.87
A perivascular niche for brain tumor stem cells. Cancer Cell (2007) 11.55
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature (2008) 10.12
Medulloblastoma comprises four distinct molecular variants. J Clin Oncol (2010) 8.06
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet (2012) 7.61
Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol (2011) 6.67
Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol (2006) 5.96
Subtypes of medulloblastoma have distinct developmental origins. Nature (2010) 5.94
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One (2008) 5.86
Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature (2008) 5.59
Radial glia cells are candidate stem cells of ependymoma. Cancer Cell (2005) 5.21
Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors. N Engl J Med (2015) 5.03
A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature (2012) 5.02
Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia. Nat Genet (2011) 4.93
Novel mutations target distinct subgroups of medulloblastoma. Nature (2012) 4.82
Dissecting the genomic complexity underlying medulloblastoma. Nature (2012) 4.77
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat Genet (2009) 4.52
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol (2010) 4.48
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol (2010) 4.23
Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature (2012) 4.13
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol (2012) 3.88
Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature (2010) 3.70
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet (2013) 3.51
Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. J Pathol (2009) 3.32
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J Clin Oncol (2011) 3.23
International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathol (2014) 3.21
Histological classification and molecular genetics of meningiomas. Lancet Neurol (2006) 3.19
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy. Clin Cancer Res (2010) 3.05
Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin. Cancer Res (2007) 3.05
Medulloblastomics: the end of the beginning. Nat Rev Cancer (2012) 3.01
Notch1 and notch2 have opposite effects on embryonal brain tumor growth. Cancer Res (2004) 2.90
Vaccination with tumor lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma. Cancer Res (2004) 2.89
beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee. J Clin Oncol (2005) 2.84
Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance. Cancer Discov (2011) 2.77
Dual and opposing roles of primary cilia in medulloblastoma development. Nat Med (2009) 2.73
The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma. Proc Natl Acad Sci U S A (2009) 2.72
A molecular fingerprint for medulloblastoma. Cancer Res (2003) 2.66
Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer Discov (2012) 2.61
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev (2009) 2.58
CT and MRI early vessel signs reflect clot composition in acute stroke. Stroke (2011) 2.52
Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA (2012) 2.49
Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC. Cancer Cell (2012) 2.45
Development of mice expressing a single D-type cyclin. Genes Dev (2002) 2.43
Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas. J Clin Oncol (2006) 2.41
Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis. Cell Cycle (2006) 2.37
Pathology of peripheral nerve sheath tumors: diagnostic overview and update on selected diagnostic problems. Acta Neuropathol (2012) 2.35
Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis. Lancet Oncol (2012) 2.34
Neurocognitive consequences of risk-adapted therapy for childhood medulloblastoma. J Clin Oncol (2005) 2.34
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. Cancer Res (2003) 2.30
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. Sci Signal (2009) 2.23
Atypical teratoid/rhabdoid tumors (ATRT): improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy. J Clin Oncol (2005) 2.19
Physiochemical drug properties associated with in vivo toxicological outcomes. Bioorg Med Chem Lett (2008) 2.17
Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma. J Clin Oncol (2004) 2.16
Transcriptomic versus chromosomal prognostic markers and clinical outcome in uveal melanoma. Clin Cancer Res (2007) 2.15
A mouse model of the most aggressive subgroup of human medulloblastoma. Cancer Cell (2012) 2.15
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes Dev (2005) 2.14
Reactive retinal astrocytic tumors (so-called vasoproliferative tumors): histopathologic, immunohistochemical, and genetic studies of four cases. Am J Ophthalmol (2012) 2.12
Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem Cells (2009) 2.10
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability. Int J Radiat Oncol Biol Phys (2008) 2.08
Adult medulloblastoma comprises three major molecular variants. J Clin Oncol (2011) 2.07
Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clin Oncol (2010) 2.04
Pathological classification and molecular genetics of meningiomas. J Neurooncol (2010) 2.03
Burkitt's lymphoma. Lancet (2012) 2.02
Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: results from the randomized multicenter HIT-SIOP PNET 4 trial. J Clin Oncol (2012) 2.01
Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct. Acta Neuropathol (2011) 2.01
Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience. Epilepsia (2009) 1.99
Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. J Neurosci Res (2008) 1.96
Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia. Blood (2012) 1.90
mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc. Cell Metab (2013) 1.86
Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature. Cancer (2004) 1.84
Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases. Am J Surg Pathol (2005) 1.84
Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis. Arch Neurol (2011) 1.83
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues. Cancer Res (2006) 1.80
An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma. Cancer Cell (2011) 1.78
High-grade astrocytoma in very young children. Pediatr Blood Cancer (2007) 1.77
Mutation of genes affecting the RAS pathway is common in childhood acute lymphoblastic leukemia. Cancer Res (2008) 1.77
Hypercalcemia in acute lymphoblastic leukemia: an overview. J Pediatr Hematol Oncol (2009) 1.76
Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression. Clin Cancer Res (2008) 1.75