Published in Nat Genet on February 06, 2011
Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00137111
Genomics for the world. Nature (2011) 3.68
Acute lymphoblastic leukaemia. Lancet (2013) 3.44
Pediatric acute lymphoblastic leukemia: where are we going and how do we get there? Blood (2012) 2.82
Fast and accurate inference of local ancestry in Latino populations. Bioinformatics (2012) 2.30
New approaches to disease mapping in admixed populations. Nat Rev Genet (2011) 2.22
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia. JAMA (2015) 2.20
Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study. Lancet Oncol (2015) 2.15
Current status of genome-wide association studies in cancer. Hum Genet (2011) 2.14
Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia. Blood (2011) 1.88
Inherited NUDT15 variant is a genetic determinant of mercaptopurine intolerance in children with acute lymphoblastic leukemia. J Clin Oncol (2015) 1.84
RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference. Am J Hum Genet (2013) 1.82
Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst (2013) 1.81
Concordance of DMET plus genotyping results with those of orthogonal genotyping methods. Clin Pharmacol Ther (2012) 1.62
Differing effects of metformin on glycemic control by race-ethnicity. J Clin Endocrinol Metab (2014) 1.61
Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group. J Clin Oncol (2012) 1.52
Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. Nat Genet (2013) 1.45
ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia. J Clin Oncol (2012) 1.39
Associations between genome-wide Native American ancestry, known risk alleles and B-cell ALL risk in Hispanic children. Leukemia (2013) 1.33
A 50-year journey to cure childhood acute lymphoblastic leukemia. Semin Hematol (2013) 1.32
Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia. Pediatr Blood Cancer (2012) 1.29
Treatment outcomes in black and white children with cancer: results from the SEER database and St Jude Children's Research Hospital, 1992 through 2007. J Clin Oncol (2012) 1.25
Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine. Blood (2015) 1.19
A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome. Cell Rep (2016) 1.18
Genome-wide study of methotrexate clearance replicates SLCO1B1. Blood (2012) 1.17
Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics (2013) 1.11
Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia. Leukemia (2012) 1.10
Inherited genetic variation in childhood acute lymphoblastic leukemia. Blood (2015) 1.09
Rare allelic forms of PRDM9 associated with childhood leukemogenesis. Genome Res (2012) 1.09
Recent trends in survival of adult patients with acute leukemia: overall improvements, but persistent and partly increasing disparity in survival of patients from minority groups. Haematologica (2012) 1.09
A systematic review of strategies that increase the recruitment and retention of African American adults in genetic and genomic studies. ABNF J (2011) 1.09
Toward the Cure of All Children With Cancer Through Collaborative Efforts: Pediatric Oncology As a Global Challenge. J Clin Oncol (2015) 1.06
A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. Blood (2014) 1.04
Improved ancestry inference using weights from external reference panels. Bioinformatics (2013) 1.03
Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations. BMC Genet (2012) 1.01
Significance of ethnicity in the risk of acute graft-versus-host disease and leukemia relapse after unrelated donor hematopoietic stem cell transplantation. Biol Blood Marrow Transplant (2013) 1.00
Softwares and methods for estimating genetic ancestry in human populations. Hum Genomics (2013) 1.00
A Method for Inferring an Individual's Genetic Ancestry and Degree of Admixture Associated with Six Major Continental Populations. Front Genet (2013) 0.99
Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities. Hum Genomics (2015) 0.98
Biology of childhood acute lymphoblastic leukemia. Pediatr Clin North Am (2015) 0.97
Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia. Cancer (2013) 0.96
Examining racial differences in diffuse large B-cell lymphoma presentation and survival. Leuk Lymphoma (2013) 0.95
HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies. Blood (2014) 0.94
Genetic ancestry is associated with colorectal adenomas and adenocarcinomas in Latino populations. Eur J Hum Genet (2014) 0.92
Genomic ancestry and somatic alterations correlate with age at diagnosis in Hispanic children with B-cell acute lymphoblastic leukemia. Am J Hematol (2014) 0.92
A twist on admixture mapping. Nat Genet (2011) 0.92
Enhanced methods for local ancestry assignment in sequenced admixed individuals. PLoS Comput Biol (2014) 0.91
Genome science and health disparities: a growing success story? Genome Med (2013) 0.90
Enhanced localization of genetic samples through linkage-disequilibrium correction. Am J Hum Genet (2013) 0.89
Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children. Nat Commun (2015) 0.89
Cancer pharmacogenomics. Clin Pharmacol Ther (2011) 0.89
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. Blood (2015) 0.87
Predictors of acute chemotherapy-associated toxicity in patients with Ewing sarcoma. Pediatr Blood Cancer (2011) 0.87
Using germline genomics to individualize pediatric cancer treatments. Clin Cancer Res (2012) 0.87
Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study. PLoS One (2012) 0.87
GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL. Blood (2013) 0.87
Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response. Pharmacogenomics J (2011) 0.86
A Heritable Missense Polymorphism in CDKN2A Confers Strong Risk of Childhood Acute Lymphoblastic Leukemia and Is Preferentially Selected during Clonal Evolution. Cancer Res (2015) 0.86
Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma. Cancer (2016) 0.85
Inherited variation in the PARP1 gene and survival from melanoma. Int J Cancer (2014) 0.85
Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait. Clin Pharmacol Ther (2016) 0.82
Graft-versus-Host Disease after HLA-Matched Sibling Bone Marrow or Peripheral Blood Stem Cell Transplantation: Comparison of North American Caucasian and Japanese Populations. Biol Blood Marrow Transplant (2016) 0.82
What does genomic medicine mean for diverse populations? Mol Genet Genomic Med (2014) 0.82
Correlation analysis of genetic admixture and social identification with body mass index in a Native American community. Am J Hum Biol (2014) 0.82
Multilocus genotypes of relevance for drug metabolizing enzymes and therapy with thiopurines in patients with acute lymphoblastic leukemia. Front Genet (2013) 0.82
Genetic ancestry and risk of mortality among U.S. Latinas with breast cancer. Cancer Res (2013) 0.82
Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent. Pharmacogenomics J (2013) 0.80
Genetic ancestry of participants in the National Children's Study. Genome Biol (2014) 0.80
Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. Carcinogenesis (2016) 0.80
Background gene expression networks significantly enhance drug response prediction by transcriptional profiling. Pharmacogenomics J (2011) 0.80
Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes. Oncotarget (2016) 0.79
Pharmacogenetics predictive of response and toxicity in acute lymphoblastic leukemia therapy. Blood Rev (2015) 0.79
Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia. J Clin Oncol (2016) 0.79
Clinical significance of MYT1L gene polymorphisms in Chinese patients with gastric cancer. PLoS One (2013) 0.79
A step toward slaying the hydra of second cancers. Nat Med (2011) 0.79
What are our AIMs? Interdisciplinary Perspectives on the Use of Ancestry Estimation in Disease Research. AJOB Prim Res (2012) 0.79
Family-based exome-wide assessment of maternal genetic effects on susceptibility to childhood B-cell acute lymphoblastic leukemia in hispanics. Cancer (2016) 0.78
Generalized admixture mapping for complex traits. G3 (Bethesda) (2013) 0.77
Genetic abnormalities associated with acute lymphoblastic leukemia. Cancer Sci (2016) 0.76
Genomic clues to ethnic differences in ALL. Blood (2014) 0.76
Inferring ancestry from population genomic data and its applications. Front Genet (2014) 0.76
A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology. Nat Commun (2016) 0.76
High expression of ID family and IGJ genes signature as predictor of low induction treatment response and worst survival in adult Hispanic patients with B-acute lymphoblastic leukemia. J Exp Clin Cancer Res (2016) 0.76
Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility. PLoS One (2017) 0.76
Policy-ready science. Nat Genet (2011) 0.75
Genetics: chemotherapy alters ancestry relapse-risk differences in childhood ALL. Nat Rev Clin Oncol (2011) 0.75
Prevalence and Predictors of Overweight and Obesity Among a Multiethnic Population of Pediatric Acute Lymphoblastic Leukemia Survivors: A Cross-Sectional Assessment. J Pediatr Hematol Oncol (2016) 0.75
Mutant PRPS1: a new therapeutic target in relapsed acute lymphoblastic leukemia. Nat Med (2015) 0.75
Dead wrong: the growing list of racial/ethnic disparities in childhood mortality. J Pediatr (2015) 0.75
IL1B-CGTC haplotype is associated with colorectal cancer in admixed individuals with increased African ancestry. Sci Rep (2017) 0.75
Impact of NUDT15 polymorphisms on thiopurines-induced myelotoxicity and thiopurines tolerance dose. Oncotarget (2017) 0.75
Variability in Cancer Risk and Outcomes Within US Latinos by National Origin and Genetic Ancestry. Curr Epidemiol Rep (2016) 0.75
Proceedings of the Tenth Annual UT-ORNL-KBRIN Bioinformatics Summit 2011. BMC Bioinformatics (2011) 0.75
Philadelphia Chromosome-like Acute Lymphoblastic Leukemia. Clin Lymphoma Myeloma Leuk (2017) 0.75
Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia. Leukemia (2017) 0.75
Genome-wide study links PNPLA3 variant with elevated hepatic transaminase after acute lymphoblastic leukemia therapy. Clin Pharmacol Ther (2017) 0.75
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Treatment of acute lymphoblastic leukemia. N Engl J Med (2006) 11.30
Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med (2009) 7.95
Estimating local ancestry in admixed populations. Am J Hum Genet (2008) 5.90
Model-based clustering and data transformations for gene expression data. Bioinformatics (2001) 4.79
Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital. Blood (2004) 4.21
A genomewide admixture mapping panel for Hispanic/Latino populations. Am J Hum Genet (2007) 3.85
Survival variability by race and ethnicity in childhood acute lymphoblastic leukemia. JAMA (2003) 3.07
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia. Blood (2000) 2.92
Results of therapy for acute lymphoblastic leukemia in black and white children. JAMA (2003) 2.77
Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA (2009) 2.72
Racial differences in the survival of childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group Study. J Clin Oncol (2000) 2.40
Racial and ethnic differences in survival of children with acute lymphoblastic leukemia. Blood (2002) 2.17
Race and outcome in childhood acute lymphoblastic leukemia. JAMA (2003) 1.65
Improved outcome with delayed intensification for children with acute lymphoblastic leukemia and intermediate presenting features: a Childrens Cancer Group phase III trial. J Clin Oncol (1993) 1.49
Intensification of therapy for children with lower-risk acute lymphoblastic leukemia: long-term follow-up of patients treated on Children's Cancer Group Trial 1881. J Clin Oncol (2003) 1.27
Influence of race and socioeconomic status on outcome of children treated for childhood acute lymphoblastic leukemia. Curr Opin Pediatr (2004) 1.14
Ethnic group and survival from childhood cancer: report from the UK Children's Cancer Study Group. Br J Cancer (2000) 1.04
Duration of hospitalization as a measure of cost on Children's Cancer Group acute lymphoblastic leukemia studies. J Clin Oncol (2001) 0.98
Survival of children and adolescents with acute lymphoid leukemia. A study of American Indians and Hispanic and non-Hispanic whites treated in New Mexico (1969 to 1986). Cancer (1991) 0.92
Factors affecting survival in White and Asian children with acute lymphoblastic leukaemia. Br J Cancer (2000) 0.92
Ethnicity and cure rates of Texas children with acute lymphoid leukemia. Cancer (1996) 0.92
Modified BFM therapy for children with previously untreated acute lymphoblastic leukemia and unfavorable prognostic features. Report of Children's Cancer Study Group Study CCG-193P. Am J Pediatr Hematol Oncol (1988) 0.88
Finding the missing heritability of complex diseases. Nature (2009) 67.95
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol (2010) 26.41
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science (2009) 25.61
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood (2009) 23.52
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Influenza-associated hospitalizations in the United States. JAMA (2004) 18.23
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature (2007) 17.68
Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J Clin Oncol (2003) 17.67
Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (2005) 17.19
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med (2009) 15.02
Probable person-to-person transmission of avian influenza A (H5N1). N Engl J Med (2005) 14.59
Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet (2005) 14.09
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Genotype, haplotype and copy-number variation in worldwide human populations. Nature (2008) 12.40
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol (2009) 12.13
Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell (2002) 11.83
Treatment of acute lymphoblastic leukemia. N Engl J Med (2006) 11.30
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet (2010) 10.75
Prevention and control of influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010. MMWR Recomm Rep (2010) 10.59
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med (2009) 10.54
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature (2008) 10.12
The allelic architecture of human disease genes: common disease-common variant...or not? Hum Mol Genet (2002) 10.08
The global circulation of seasonal influenza A (H3N2) viruses. Science (2008) 10.05
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
Large-scale sequence analysis of avian influenza isolates. Science (2006) 9.87
Automating sequence-based detection and genotyping of SNPs from diploid samples. Nat Genet (2006) 9.04
Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice. Science (2009) 8.61
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science (2007) 8.38
Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. JAMA (2006) 8.06
Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med (2009) 7.95
Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals. J Virol (2005) 7.88
Acute lymphoblastic leukemia. N Engl J Med (2004) 7.83
Genotype-imputation accuracy across worldwide human populations. Am J Hum Genet (2009) 7.28
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol Ther (2009) 6.91
Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med (2005) 6.83
Age and acute myeloid leukemia. Blood (2006) 6.46
Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model. Proc Natl Acad Sci U S A (2006) 6.35
A distinct lineage of influenza A virus from bats. Proc Natl Acad Sci U S A (2012) 6.27
Transmission of equine influenza virus to dogs. Science (2005) 6.11
SCAN: SNP and copy number annotation. Bioinformatics (2009) 5.96
Risk of influenza A (H5N1) infection among poultry workers, Hong Kong, 1997-1998. J Infect Dis (2002) 5.92
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009. MMWR Recomm Rep (2009) 5.80
Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. Lancet (2005) 5.70
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. N Engl J Med (2014) 5.37
Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2007. MMWR Recomm Rep (2007) 5.32
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study. Lancet Oncol (2009) 5.22
Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide. J Infect Dis (2007) 5.21
Prevention and Control of Influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep (2006) 5.19
Outcomes for children and adolescents with cancer: challenges for the twenty-first century. J Clin Oncol (2010) 5.11
Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group. J Clin Oncol (2012) 5.08