DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation.

Retinoic acid receptor signaling preserves tendon stem cell characteristics and prevents spontaneous differentiation in vitrox. Stem Cell Res Ther (2016) 1.39

DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs. PLoS One (2011) 1.27

Genetic and molecular control of osterix in skeletal formation. J Cell Biochem (2013) 1.19

DNA methylation in stem cell renewal and multipotency. Stem Cell Res Ther (2011) 1.00

DNA methylation and differentiation: silencing, upregulation and modulation of gene expression. Epigenomics (2013) 0.97

Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2. BMC Genomics (2012) 0.93

Osterix and NO66 histone demethylase control the chromatin of Osterix target genes during osteoblast differentiation. J Bone Miner Res (2014) 0.87

MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells. BMC Mol Biol (2014) 0.85

DNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation. Stem Cells Int (2016) 0.84

Impact of tissue-specific stem cells on lineage-specific differentiation: a focus on the musculoskeletal system. Stem Cell Rev (2015) 0.83

PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation. J Cell Sci (2012) 0.81

Regulation of the bone-restricted IFITM-like (Bril) gene transcription by Sp and Gli family members and CpG methylation. J Biol Chem (2013) 0.81

Epigenetic Regulation of Bone Remodeling and Its Impacts in Osteoporosis. Int J Mol Sci (2016) 0.80

Significance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective. Stem Cells Dev (2014) 0.78

Effect of the harvest procedure and tissue site on the osteogenic function of and gene expression in human mesenchymal stem cells. Int J Mol Med (2016) 0.77

Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy. Sci Rep (2016) 0.75

Perinatal DNA methylation at CDKN2A is associated with offspring bone mass: Findings from the Southampton Women's Survey. J Bone Miner Res (2017) 0.75

Tet-mediated DNA demethylation is required for SWI/SNF-dependent chromatin remodeling and histone modifying activities that trigger expression of the Sp7 osteoblast master gene during mesenchymal lineage commitment. Mol Cell Biol (2017) 0.75

Hierarchical model of gene regulation by transforming growth factor beta. Proc Natl Acad Sci U S A (2003) 2.37

TGF-beta induces proangiogenic and antiangiogenic factors via parallel but distinct Smad pathways. Kidney Int (2004) 1.95

Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res (2003) 1.59

Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. J Biol Chem (2004) 1.46

Identification of novel regulators associated with early-phase osteoblast differentiation. J Bone Miner Res (2004) 1.20

Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development. J Bone Miner Res (2002) 1.19

Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts. Bone (2005) 1.17

Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation. J Bone Miner Res (2003) 1.14

Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status. Metabolomics (2011) 1.06

Catabolic factors and osteoarthritis-conditioned medium inhibit chondrogenesis of human mesenchymal stem cells. Tissue Eng Part A (2011) 1.06

Epigenetics: DNA demethylation promotes skeletal myotube maturation. FASEB J (2011) 1.06

Smad3 mediates the TGF-beta-induced contraction of type I collagen gels by mouse embryo fibroblasts. Cell Motil Cytoskeleton (2003) 1.05

Osteo-transcriptomics of human mesenchymal stem cells: accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced osteogenesis. Bone (2009) 1.03

Inference of dynamical gene-regulatory networks based on time-resolved multi-stimuli multi-experiment data applying NetGenerator V2.0. BMC Syst Biol (2013) 1.01

Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism. Bone (2009) 0.94

Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway. Breast Cancer Res (2004) 0.91

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation. Bone (2006) 0.89

Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1. Biomaterials (2013) 0.88

Developing computational model-based diagnostics to analyse clinical chemistry data. Brief Bioinform (2010) 0.86

MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells. BMC Mol Biol (2014) 0.85

Integrating gene expression and GO classification for PCA by preclustering. BMC Bioinformatics (2010) 0.83

Integration of known transcription factor binding site information and gene expression data to advance from co-expression to co-regulation. Genomics Proteomics Bioinformatics (2007) 0.80

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans. Toxicol Appl Pharmacol (2012) 0.80

Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization. BMC Bioinformatics (2010) 0.78

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature (2016) 0.77

Dynamic modelling of microRNA regulation during mesenchymal stem cell differentiation. BMC Syst Biol (2013) 0.76

Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks. J Appl Toxicol (2012) 0.76

Identification of novel bacterial M.SssI DNA methyltransferase inhibitors. J Biomol Screen (2012) 0.76

Comparative proteome approach demonstrates that platelet-derived growth factor C and D efficiently induce proliferation while maintaining multipotency of hMSCs. Exp Cell Res (2013) 0.76

Biological effects of rinsing morsellised bone grafts before and after impaction. Int Orthop (2008) 0.75