Published in Bone on June 13, 2006
Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis. Mol Cancer (2010) 1.36
Novel regulators of Fgf23 expression and mineralization in Hyp bone. Mol Endocrinol (2009) 1.34
Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS One (2009) 1.19
Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis. Genome Biol (2014) 1.17
Modulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancer. Endocrinology (2008) 1.12
Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA. Mol Endocrinol (2009) 1.06
Dose-dependent effects of Runx2 on bone development. J Bone Miner Res (2009) 1.06
Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are down-regulated throughout osteogenesis in type 1 diabetes mellitus. Endocrinology (2007) 1.06
Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells. Osteoporos Int (2011) 0.92
Representing ontogeny through ontology: a developmental biologist's guide to the gene ontology. Mol Reprod Dev (2010) 0.89
Possible functional links among brain- and skull-related genes selected in modern humans. Front Psychol (2015) 0.89
Polycomb PRC2 complex mediates epigenetic silencing of a critical osteogenic master regulator in the hippocampus. Biochim Biophys Acta (2016) 0.78
Osteogenic potential of osteoblasts from neonatal rats born to mothers treated with caffeine throughout pregnancy. BMC Musculoskelet Disord (2015) 0.75
Cyclooxygenase-2 inhibition does not impair block bone grafts healing in rabbit model. J Mol Histol (2013) 0.75
Endocrine regulation of energy metabolism by the skeleton. Cell (2007) 10.41
Leptin regulates bone formation via the sympathetic nervous system. Cell (2002) 5.95
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell (2008) 5.93
Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell (2010) 5.08
Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc Natl Acad Sci U S A (2008) 4.77
Endocrine regulation of male fertility by the skeleton. Cell (2011) 3.20
POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res (2003) 2.45
Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nat Med (2010) 2.32
Estimating dopamine D₂ receptor occupancy for doses of 8 antipsychotics: a meta-analysis. J Clin Psychopharmacol (2013) 2.07
Efficacy of serotonin inhibition in mouse models of bone loss. J Bone Miner Res (2011) 1.84
Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice. Bone (2011) 1.75
Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination. J Biol Chem (2003) 1.72
Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a. Diabetes (2013) 1.68
Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation. J Cell Biol (2010) 1.49
Minor neurological dysfunction and behaviour in 9-year-old children born at term: evidence for sex dimorphism. Dev Med Child Neurol (2013) 1.38
A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J Biol Chem (2005) 1.30
An ELISA-based method to quantify osteocalcin carboxylation in mice. Biochem Biophys Res Commun (2010) 1.29
Parathyroid hormone bone anabolic action requires Cbfa1/Runx2-dependent signaling. Mol Endocrinol (2002) 1.26
Identification of novel regulators associated with early-phase osteoblast differentiation. J Bone Miner Res (2004) 1.20
Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development. J Bone Miner Res (2002) 1.19
Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts. Bone (2005) 1.17
Increased oocyte degeneration and follicular atresia during the estrous cycle in anti-Müllerian hormone null mice. Endocrinology (2007) 1.15
Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation. J Bone Miner Res (2003) 1.14
Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production. Endocrinology (2008) 1.09
Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status. Metabolomics (2011) 1.06
Epigenetics: DNA demethylation promotes skeletal myotube maturation. FASEB J (2011) 1.06
Narrow band imaging is a new technique in visualization of recurrent respiratory papillomatosis. Laryngoscope (2012) 1.04
NTCP models for patient-rated xerostomia and sticky saliva after treatment with intensity modulated radiotherapy for head and neck cancer: the role of dosimetric and clinical factors. Radiother Oncol (2012) 1.03
DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation. Biochim Biophys Acta (2011) 1.00
Characterization of an osteoblast-specific enhancer element in the CBFA1 gene. J Biol Chem (2002) 0.98
Microarray analysis of bone morphogenetic protein, transforming growth factor beta, and activin early response genes during osteoblastic cell differentiation. J Bone Miner Res (2002) 0.93
Lrp5 and bone formation : A serotonin-dependent pathway. Ann N Y Acad Sci (2010) 0.93
Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway. Breast Cancer Res (2004) 0.91
External validation of three dimensional conformal radiotherapy based NTCP models for patient-rated xerostomia and sticky saliva among patients treated with intensity modulated radiotherapy. Radiother Oncol (2011) 0.91
The effect of a clinical pharmacist-led training programme on intravenous medication errors: a controlled before and after study. BMJ Qual Saf (2013) 0.90
Genetic analysis of Lrp5 function in osteoblast progenitors. Calcif Tissue Int (2010) 0.89
Haplotype-specific expression of the human PDGFRA gene correlates with the risk of glioblastomas. Int J Cancer (2008) 0.88
Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1. Biomaterials (2013) 0.88
Recycling of EGFR and ErbB2 is associated with impaired Hrs tyrosine phosphorylation and decreased deubiquitination by AMSH. Cell Signal (2012) 0.87
A systematic review and meta-analysis on the prevalence of Dupuytren disease in the general population of Western countries. Plast Reconstr Surg (2014) 0.86
Developing computational model-based diagnostics to analyse clinical chemistry data. Brief Bioinform (2010) 0.86
MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells. BMC Mol Biol (2014) 0.85
Contamination rates of three urine-sampling methods to assess bacteriuria in pregnant women. Obstet Gynecol (2013) 0.83
Prevalence of Dupuytren disease in The Netherlands. Plast Reconstr Surg (2013) 0.83
Interaction of PDGFRA promoter haplotypes and maternal environmental exposures in the risk of spina bifida. Birth Defects Res A Clin Mol Teratol (2009) 0.83
Co-dependence of bone and energy metabolisms. Arch Biochem Biophys (2010) 0.83
Modification of LDL with oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC) results in a novel form of minimally modified LDL that modulates gene expression in macrophages. Biochim Biophys Acta (2008) 0.83
Selective formation of ErbB-2/ErbB-3 heterodimers depends on the ErbB-3 affinity of epidermal growth factor-like ligands. J Biol Chem (2003) 0.82
Bacterial adhesion forces with substratum surfaces and the susceptibility of biofilms to antibiotics. Antimicrob Agents Chemother (2012) 0.81
Integration of known transcription factor binding site information and gene expression data to advance from co-expression to co-regulation. Genomics Proteomics Bioinformatics (2007) 0.80
Subtherapeutic Posaconazole Exposure and Treatment Outcome in Patients With Invasive Fungal Disease. Ther Drug Monit (2015) 0.80
'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans. Toxicol Appl Pharmacol (2012) 0.80
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization. BMC Bioinformatics (2010) 0.78
Ligand depletion negatively controls the mitogenic activity of epidermal growth factor. Exp Cell Res (2005) 0.78
Negative constraints underlie the ErbB specificity of epidermal growth factor-like ligands. J Biol Chem (2006) 0.78
The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation. Cell Signal (2013) 0.78
Patterns of Dupuytren disease in fingers: studying correlations with a multivariate ordinal logit model. Plast Reconstr Surg (2014) 0.78
Cbl and Itch binding sites in ERBB4 CYT-1 and CYT-2 mediate K48- and K63-polyubiquitination, respectively. Cell Signal (2012) 0.78
A brief version of the Subjects' Response to Antipsychotics questionnaire to evaluate treatment effects. Schizophr Res (2013) 0.78
Structural analysis of an epidermal growth factor/transforming growth factor-alpha chimera with unique ErbB binding specificity. J Biol Chem (2003) 0.78
Epidermal growth factor mutant with wild-type affinity for both ErbB1 and ErbB3. Biochemistry (2006) 0.77
Health-related quality of life in epidermolysis bullosa: Validation of the Dutch QOLEB questionnaire and assessment in the Dutch population. Acta Derm Venereol (2014) 0.77
Role of the C-terminal linear region of EGF-like growth factors in ErbB specificity. Growth Factors (2009) 0.77
Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature (2016) 0.77
Pax1/E2a double-mutant mice develop non-lethal neural tube defects that resemble human malformations. Transgenic Res (2005) 0.77
Quantification of ErbB3 receptor density on human breast cancer cells, using a stable radio-labeled mutant of NRG1beta. Biochem Biophys Res Commun (2008) 0.76
Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks. J Appl Toxicol (2012) 0.76
A regulating element essential for PDGFRA transcription is recognized by neural tube defect-associated PRX homeobox transcription factors. Biochim Biophys Acta (2002) 0.76
Prostaglandin F2 alpha induces unsynchronized intracellular calcium oscillations in monolayers of gap junctionally coupled NRK fibroblasts. Pflugers Arch (2003) 0.76
Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display. Biochemistry (2002) 0.76
ErbB2 and ErbB4 Cbl binding sites can functionally replace the ErbB1 Cbl binding site. Cell Signal (2009) 0.76
Identification of novel bacterial M.SssI DNA methyltransferase inhibitors. J Biomol Screen (2012) 0.76
Comparative proteome approach demonstrates that platelet-derived growth factor C and D efficiently induce proliferation while maintaining multipotency of hMSCs. Exp Cell Res (2013) 0.76
Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis. J Neuroimmunol (2010) 0.76
Chronic Stress and Adolescents' Mental Health: Modifying Effects of Basal Cortisol and Parental Psychiatric History. The TRAILS Study. J Abnorm Child Psychol (2015) 0.76
Efficacy of tadalafil on erectile dysfunction in male patients using antipsychotics: a double-blind, placebo-controlled, crossover pilot study. J Clin Psychopharmacol (2014) 0.75
Association between methylation of the SLC6A4 promoter region in peripheral blood leukocytes and methylation in amygdala tissue. Psychosom Med (2014) 0.75
Epidermal growth factor contains both positive and negative determinants for interaction with ErbB-2/ErbB-3 heterodimers. Biochemistry (2002) 0.75
Closed-form confidence intervals on measures of precision for an interlaboratory study. J Biopharm Stat (2007) 0.75
[Control of body mass by leptin occurs through the sympathetic nervous system]. Med Sci (Paris) (2003) 0.75
Epidermal growth factor receptor-induced activator protein 1 activity controls density-dependent growth inhibition in normal rat kidney fibroblasts. Mol Biotechnol (2006) 0.75