Published in J Immunol on February 02, 2011
Accumulation of memory precursor CD8 T cells in regressing tumors following combination therapy with vaccine and anti-PD-1 antibody. Cancer Res (2014) 1.09
Pro-inflammatory chemokine CCL2 (MCP-1) promotes healing in diabetic wounds by restoring the macrophage response. PLoS One (2014) 0.97
Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection. J Virol (2012) 0.92
5-Aza-2'-deoxycytidine potentiates antitumour immune response induced by photodynamic therapy. Eur J Cancer (2014) 0.89
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nat Med (2012) 0.89
NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade. J Immunother Cancer (2015) 0.87
Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression. Cancer Immunol Immunother (2011) 0.78
CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells. J Immunol (2012) 0.77
Pre-clinical assessment of autologous DC-based therapy in ovarian cancer patients with progressive disease. Cancer Immunol Immunother (2012) 0.76
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol (2003) 15.51
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity (2007) 12.98
Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer (2008) 9.82
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol (2005) 8.27
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J Exp Med (2008) 5.71
Mechanisms of suppression by suppressor T cells. Nat Immunol (2005) 5.52
Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exp Med (2010) 4.79
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med (2004) 4.77
Regulatory T cells in tumor immunity. Int J Cancer (2010) 4.53
CD8+ T-cell memory in tumor immunology and immunotherapy. Immunol Rev (2006) 4.49
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell (2005) 4.46
Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells. Nat Med (2001) 3.74
Monoclonal antibodies recognizing transforming growth factor-beta. Bioactivity neutralization and transforming growth factor beta 2 affinity purification. J Immunol (1989) 3.00
Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity. Proc Natl Acad Sci U S A (2009) 2.56
Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. J Immunol (2010) 2.20
Targeting the TGF beta signaling network in human neoplasia. Cancer Cell (2003) 2.16
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. Proc Natl Acad Sci U S A (1990) 2.03
Heteroclitic immunization induces tumor immunity. J Exp Med (1998) 1.92
Cutaneous malignant melanoma. Mayo Clin Proc (2006) 1.88
A single heteroclitic epitope determines cancer immunity after xenogeneic DNA immunization against a tumor differentiation antigen. J Immunol (2003) 1.81
B16 as a mouse model for human melanoma. Curr Protoc Immunol (2001) 1.80
TGF-beta1 regulation of dendritic cells. Microbes Infect (1999) 1.60
Optimization of a self antigen for presentation of multiple epitopes in cancer immunity. J Clin Invest (2006) 1.59
Myeloid-derived suppressor cells. Adv Exp Med Biol (2007) 1.55
TGF-beta and regulatory T cell in immunity and autoimmunity. J Clin Immunol (2008) 1.49
Autoimmunity and tumor immunity induced by immune responses to mutations in self. Nat Med (2006) 1.41
Diversity in CD8(+) T cell differentiation. Curr Opin Immunol (2009) 1.32
Immune recognition of self in immunity against cancer. J Clin Invest (2004) 1.27
Intrinsic and extrinsic control of effector T cell survival and memory T cell development. Immunol Res (2009) 1.16
Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity. Surgery (2000) 1.15
HSP70i accelerates depigmentation in a mouse model of autoimmune vitiligo. J Invest Dermatol (2008) 1.11
Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells. Int J Cancer (2010) 1.08
Immunity to cancer through immune recognition of altered self: studies with melanoma. Adv Cancer Res (2003) 1.07
Cancer immunotherapy. N Engl J Med (2008) 0.94
Effect of the expression of transforming growth factor-beta 2 in primary human glioblastomas on immunosuppression and loss of immune surveillance. J Neurosurg (1992) 0.93
Mechanisms of immunization against cancer using chimeric antigens. Mol Ther (2008) 0.85
Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes. Vaccine (2007) 0.85
Immune rejection of mouse tumors expressing mutated self. Cancer Res (2009) 0.84
Efficacy and safety of immediate-release methylphenidate treatment for preschoolers with ADHD. J Am Acad Child Adolesc Psychiatry (2006) 11.25
Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety. N Engl J Med (2008) 10.48
Safety and tolerability of methylphenidate in preschool children with ADHD. J Am Acad Child Adolesc Psychiatry (2006) 10.19
Rationale, design, and methods of the Preschool ADHD Treatment Study (PATS). J Am Acad Child Adolesc Psychiatry (2006) 10.00
Stimulant-related reductions of growth rates in the PATS. J Am Acad Child Adolesc Psychiatry (2006) 9.98
Pharmacogenetics of methylphenidate response in preschoolers with ADHD. J Am Acad Child Adolesc Psychiatry (2006) 9.85
Management of the clinically inapparent adrenal mass ("incidentaloma"). Ann Intern Med (2003) 4.48
Concurrent validity of the anxiety disorders section of the Anxiety Disorders Interview Schedule for DSM-IV: child and parent versions. J Clin Child Adolesc Psychol (2002) 3.56
Complete Barrett's eradication endoscopic mucosal resection: an effective treatment modality for high-grade dysplasia and intramucosal carcinoma--an American single-center experience. Am J Gastroenterol (2009) 2.66
Clinical characteristics of anxiety disordered youth. J Anxiety Disord (2010) 2.59
Future directions in the treatment of neuroendocrine tumors: consensus report of the National Cancer Institute Neuroendocrine Tumor clinical trials planning meeting. J Clin Oncol (2011) 2.57
Suicide attempts and nonsuicidal self-injury in the treatment of resistant depression in adolescents: findings from the TORDIA study. J Am Acad Child Adolesc Psychiatry (2011) 2.55
Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense. J Exp Med (2004) 2.47
Treatment of Resistant Depression in Adolescents (TORDIA): week 24 outcomes. Am J Psychiatry (2010) 2.32
Defining surgical quality in gastric cancer: a RAND/UCLA appropriateness study. J Am Coll Surg (2013) 2.19
Functional impairment in children and adolescents with obsessive-compulsive disorder. J Child Adolesc Psychopharmacol (2003) 2.13
Is the risk of concomitant invasive esophageal cancer in high-grade dysplasia in Barrett's esophagus overestimated? Clin Gastroenterol Hepatol (2007) 2.07
Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res (2005) 1.90
Family-based genome-wide association scan of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2010) 1.79
Mutant HSP70 reverses autoimmune depigmentation in vitiligo. Sci Transl Med (2013) 1.66
Optimal management of gastric cancer: results from an international RAND/UCLA expert panel. Ann Surg (2014) 1.61
A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial. Ann Surg Oncol (2011) 1.54
Cancer recurrence: an important but missing variable in national cancer registries. Ann Surg Oncol (2014) 1.52
The role of surgery in the management of oesophageal cancer. Lancet Oncol (2003) 1.50
Use of a novel, web-based educational platform facilitates intraoperative training in a surgical oncology fellowship program. Ann Surg Oncol (2009) 1.47
MicroRNA expression characterizes oligometastasis(es). PLoS One (2011) 1.45
Practice parameter for the assessment and treatment of children and adolescents with autism spectrum disorder. J Am Acad Child Adolesc Psychiatry (2014) 1.45
Impairment in childhood anxiety disorders: preliminary examination of the child anxiety impact scale-parent version. J Child Adolesc Psychopharmacol (2004) 1.43
Malignancies in HIV/AIDS: from epidemiology to therapeutic challenges. AIDS (2014) 1.41
STAT1 pathway mediates amplification of metastatic potential and resistance to therapy. PLoS One (2009) 1.37
Borderline resectable pancreatic cancer: need for standardization and methods for optimal clinical trial design. Ann Surg Oncol (2013) 1.36
Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1. J Virol (2006) 1.35
Reduced white matter integrity in attention-deficit hyperactivity disorder. Neuroreport (2008) 1.31
Controlled comparison of family cognitive behavioral therapy and psychoeducation/relaxation training for child obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry (2011) 1.29
Vascular endothelial growth factor enhances endothelial cell survival and tumor radioresistance. Cancer J (2002) 1.23
Modern treatment of gastric gastrointestinal stromal tumors. World J Gastroenterol (2012) 1.22
Media ion composition controls regulatory and virulence response of Salmonella in spaceflight. PLoS One (2008) 1.19
Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol (2008) 1.18
Transhiatal versus transthoracic esophagectomy for esophageal cancer. World J Gastroenterol (2010) 1.18
Weight and leptin changes among risperidone-treated youths with autism: 6-month prospective data. Am J Psychiatry (2004) 1.16
Lipid peroxidation product 4-hydroxy-trans-2-nonenal causes endothelial activation by inducing endoplasmic reticulum stress. J Biol Chem (2012) 1.16
Moderators, mediators, and other predictors of risperidone response in children with autistic disorder and irritability. J Child Adolesc Psychopharmacol (2010) 1.15
Geriatric assessment improves prediction of surgical outcomes in older adults undergoing pancreaticoduodenectomy: a prospective cohort study. Ann Surg (2014) 1.14
Glioblastoma cells block radiation-induced programmed cell death of endothelial cells. FEBS Lett (2004) 1.14
Acrolein inhalation prevents vascular endothelial growth factor-induced mobilization of Flk-1+/Sca-1+ cells in mice. Arterioscler Thromb Vasc Biol (2011) 1.13
Surgical treatment of gastrointestinal stromal tumors in the imatinib (STI-571) era. Surgery (2003) 1.12
Oligo- and polymetastatic progression in lung metastasis(es) patients is associated with specific microRNAs. PLoS One (2012) 1.11
HSP70i accelerates depigmentation in a mouse model of autoimmune vitiligo. J Invest Dermatol (2008) 1.11
Methodological issues and controversies in clinical trials with child and adolescent patients with bipolar disorder: report of a consensus conference. J Child Adolesc Psychopharmacol (2003) 1.10
Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation. Mol Cancer Ther (2011) 1.08
Sequential pharmacotherapy for children with comorbid attention-deficit/hyperactivity and anxiety disorders. J Am Acad Child Adolesc Psychiatry (2005) 1.05
Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents. Am J Psychiatry (2003) 1.05
CYP2D6 and clinical response to atomoxetine in children and adolescents with ADHD. J Am Acad Child Adolesc Psychiatry (2007) 1.05
Testosterone-related cortical maturation across childhood and adolescence. Cereb Cortex (2012) 1.01
Defining treatment response and remission in child anxiety: signal detection analysis using the pediatric anxiety rating scale. J Am Acad Child Adolesc Psychiatry (2012) 1.00
Standardization of surgical and pathologic variables is needed in multicenter trials of adjuvant therapy for pancreatic cancer: results from the ACOSOG Z5031 trial. Ann Surg Oncol (2010) 1.00
Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells. Stem Cells (2013) 0.99
Exposure to ambient air fine particulate matter prevents VEGF-induced mobilization of endothelial progenitor cells from the bone marrow. Environ Health Perspect (2012) 0.98
HSP70i is a critical component of the immune response leading to vitiligo. Pigment Cell Melanoma Res (2011) 0.97
Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses. Cancer Res (2005) 0.97
Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens. J Immunol (2010) 0.96
Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes. J Child Psychol Psychiatry (2008) 0.96
Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. Ann Surg Oncol (2002) 0.96
Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs. Clin Exp Metastasis (2014) 0.96
Comparison of clinical features among youth with tic disorders, obsessive-compulsive disorder (OCD), and both conditions. Psychiatry Res (2010) 0.95
Characterization of the theta to beta ratio in ADHD: identifying potential sources of heterogeneity. J Atten Disord (2012) 0.94
Neoadjuvant strategies for the treatment of locally advanced esophageal cancer. J Surg Oncol (2010) 0.93
Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells. J Immunol (2010) 0.93
Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers. Cancer Res (2012) 0.93
Long-term outcome of a phase II study of docetaxel-based multimodality chemoradiotherapy for locally advanced carcinoma of the esophagus or gastroesophageal junction. Med Oncol (2010) 0.93
Genome-wide association study of the child behavior checklist dysregulation profile. J Am Acad Child Adolesc Psychiatry (2011) 0.93
Doubling of 30-Day Mortality by 90 Days After Esophagectomy: A Critical Measure of Outcomes for Quality Improvement. Ann Surg (2016) 0.91
Presence of distal intramural spread after preoperative combined-modality therapy for adenocarcinoma of the rectum: what is now the appropriate distal resection margin? Surgery (2005) 0.91
Treatment of pediatric anxiety disorders: an open-label extension of the research units on pediatric psychopharmacology anxiety study. J Child Adolesc Psychopharmacol (2002) 0.90
CD34-based enrichment of genetically engineered human T cells for clinical use results in dramatically enhanced tumor targeting. Cancer Immunol Immunother (2010) 0.90
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nat Med (2012) 0.89
Parent satisfaction in a multi-site acute trial of risperidone in children with autism: a social validity study. Psychopharmacology (Berl) (2006) 0.88
Defining the Benefit of Adjuvant Therapy Following Resection for Intrahepatic Cholangiocarcinoma. Ann Surg Oncol (2014) 0.87
Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity. Cancer Res (2007) 0.87
Multiple populations of T lymphocytes are distinguished by the level of CD4 and CD8 coexpression and require individual consideration. J Leukoc Biol (2006) 0.87
Spaceflight enhances cell aggregation and random budding in Candida albicans. PLoS One (2013) 0.86
Immunological validation of the EpitOptimizer program for streamlined design of heteroclitic epitopes. Vaccine (2007) 0.85
Transcriptional control of viral gene therapy by cisplatin. J Clin Invest (2002) 0.85
Hereditary diffuse gastric cancer: multidisciplinary case report with review of the literature. Patholog Res Int (2011) 0.84
A review of resistance patterns and phenotypic changes in gastrointestinal stromal tumors following imatinib mesylate therapy. J Gastrointest Surg (2007) 0.83
Evidence for potential relationship between SLC1A1 and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding. Am J Med Genet B Neuropsychiatr Genet (2008) 0.83
CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-β (TGF-β)-mediated suppression. Cancer Immunol Immunother (2010) 0.83
Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB. Int J Oncol (2007) 0.83
D3 or not D3... that is not the question. Lancet Oncol (2006) 0.83