Published in Bioorg Med Chem on January 11, 2011
Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assay. Antimicrob Agents Chemother (2012) 0.81
Panaxadiol and panaxatriol derivatives as anti-hepatitis B virus inhibitors. Nat Prod Bioprospect (2014) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Retrieval of crystallographically-derived molecular geometry information. J Chem Inf Comput Sci (2004) 74.81
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors. Nat Biotechnol (2008) 3.04
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nat Immunol (2008) 2.89
The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition. Clin Cancer Res (2012) 2.63
SIFTS: Structure Integration with Function, Taxonomy and Sequences resource. Nucleic Acids Res (2012) 2.61
Gigantic enhancement in response and reset time of ZnO UV nanosensor by utilizing Schottky contact and surface functionalization. Appl Phys Lett (2009) 2.54
Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion. Diabetes (2008) 2.48
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res (2006) 2.47
Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. Neuron (2011) 2.42
Selection of reliable reference genes for gene expression studies in peach using real-time PCR. BMC Mol Biol (2009) 2.35
Fluorescence optical diffusion tomography. Appl Opt (2003) 2.10
Molecular imaging of interstitial alterations in remodeling myocardium after myocardial infarction. J Am Coll Cardiol (2008) 1.97
Salt cress. A halophyte and cryophyte Arabidopsis relative model system and its applicability to molecular genetic analyses of growth and development of extremophiles. Plant Physiol (2004) 1.94
Understanding the unique characteristics of suicide in China: national psychological autopsy study. Biomed Environ Sci (2005) 1.90
Modulation of T-cell activation by malignant melanoma initiating cells. Cancer Res (2010) 1.83
Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex. Mol Cell Biol (2009) 1.82
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79
Botulinum toxin type A for the treatment of trigeminal neuralgia: results from a randomized, double-blind, placebo-controlled trial. Cephalalgia (2012) 1.78
Combined optical imaging and mammography of the healthy breast: optical contrast derived from breast structure and compression. IEEE Trans Med Imaging (2009) 1.76
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem (2011) 1.75
Imatinib targeting of KIT-mutant oncoprotein in melanoma. Clin Cancer Res (2008) 1.73
Piezoelectric field effect transistor and nanoforce sensor based on a single ZnO nanowire. Nano Lett (2006) 1.72
A multilevel adaptive finite element algorithm for bioluminescence tomography. Opt Express (2006) 1.71
Tomographic optical breast imaging guided by three-dimensional mammography. Appl Opt (2003) 1.69
Effects of resistant starch, a non-digestible fermentable fiber, on reducing body fat. Obesity (Silver Spring) (2006) 1.66
Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease. J Neurosci (2004) 1.66
Reconstructing chromosphere concentration images directly by continuous-wave diffuse optical tomography. Opt Lett (2004) 1.61
Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans. J Physiol (2004) 1.60
Dual molecular imaging for targeting metalloproteinase activity and apoptosis in atherosclerosis: molecular imaging facilitates understanding of pathogenesis. J Nucl Cardiol (2009) 1.60
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem (2002) 1.60
Coating optimization of superparamagnetic iron oxide nanoparticles for high T2 relaxivity. Nano Lett (2010) 1.58
Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells. J Biol Chem (2005) 1.56
Down-regulated expression of SATB2 is associated with metastasis and poor prognosis in colorectal cancer. J Pathol (2009) 1.53
Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs. J Pharmacol Toxicol Methods (2006) 1.50
L-type calcium current recovery versus ventricular repolarization: preserved membrane-stabilizing mechanism for different QT intervals across species. Heart Rhythm (2007) 1.48
Dissecting yield-associated loci in super hybrid rice by resequencing recombinant inbred lines and improving parental genome sequences. Proc Natl Acad Sci U S A (2013) 1.48
Risk factors for predicting postoperative complications after open infrarenal abdominal aortic aneurysm repair: results from a single vascular center in China. J Clin Anesth (2013) 1.46
Meta-analysis on the possible association between in vitro fertilization and cancer risk. Int J Gynecol Cancer (2013) 1.46
Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma. J Cancer Res Clin Oncol (2007) 1.44
RXR is an essential component of the oncogenic PML/RARA complex in vivo. Cancer Cell (2007) 1.43
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma. Clin Cancer Res (2009) 1.43
Loss of halophytism by interference with SOS1 expression. Plant Physiol (2009) 1.43
High-strain sensors based on ZnO nanowire/polystyrene hybridized flexible films. Adv Mater (2011) 1.41
The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration. J Biol Chem (2008) 1.39
Flexible solid-state supercapacitors based on carbon nanoparticles/MnO2 nanorods hybrid structure. ACS Nano (2011) 1.39
Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma. Cancer Genet Cytogenet (2006) 1.38
Experimental validation of a three-dimensional linear system model for breast tomosynthesis. Med Phys (2009) 1.37
Expression of CD147 on monocytes/macrophages in rheumatoid arthritis: its potential role in monocyte accumulation and matrix metalloproteinase production. Arthritis Res Ther (2005) 1.34
Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas. J Physiol (2009) 1.34
The prevalence of prostatitis-like symptoms in China. J Urol (2009) 1.33
Tumor cyclooxygenase 2-dependent suppression of dendritic cell function. Clin Cancer Res (2003) 1.33
Circulating microRNA profiles as potential biomarkers for diagnosis of papillary thyroid carcinoma. J Clin Endocrinol Metab (2012) 1.33
Biophysical mechanisms of MRI signal frequency contrast in multiple sclerosis. Proc Natl Acad Sci U S A (2012) 1.32
Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells. Autophagy (2012) 1.32
Plant cyclopeptides. Chem Rev (2006) 1.31
Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics. J Pharmacol Exp Ther (2002) 1.30
Molecular imaging of matrix metalloproteinase in atherosclerotic lesions: resolution with dietary modification and statin therapy. J Am Coll Cardiol (2008) 1.29
Regulation of calcium in pancreatic α- and β-cells in health and disease. Cell Calcium (2011) 1.29
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis. J Clin Invest (2002) 1.29
EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A. Proc Natl Acad Sci U S A (2008) 1.28
Genetic incompatibilities are widespread within species. Nature (2013) 1.28
The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase. Cancer Res (2005) 1.28
A sumoylation site in PML/RARA is essential for leukemic transformation. Cancer Cell (2005) 1.27
Lamin B receptor plays a role in stimulating nuclear envelope production and targeting membrane vesicles to chromatin during nuclear envelope assembly through direct interaction with importin beta. J Cell Sci (2007) 1.26
Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. Cell Metab (2009) 1.26
A reference methylome database and analysis pipeline to facilitate integrative and comparative epigenomics. PLoS One (2013) 1.26
COX-2-dependent stabilization of survivin in non-small cell lung cancer. FASEB J (2003) 1.24
Optimal linear inverse solution with multiple priors in diffuse optical tomography. Appl Opt (2005) 1.24
Beta3 subunits promote expression and nicotine-induced up-regulation of human nicotinic alpha6* nicotinic acetylcholine receptors expressed in transfected cell lines. Mol Pharmacol (2006) 1.23
Pentamidine reduces hERG expression to prolong the QT interval. Br J Pharmacol (2005) 1.23
Oncogenic function of microtubule end-binding protein 1 in breast cancer. J Pathol (2010) 1.22
Minimally invasive treatment combined with cytokine-induced killer cells therapy lower the short-term recurrence rates of hepatocellular carcinomas. J Immunother (2008) 1.22
Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis. PLoS Genet (2012) 1.20
p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells. Cancer Res (2007) 1.20
Microtubule-interacting drugs for cancer treatment. Trends Pharmacol Sci (2003) 1.20
Effects of nurse-delivered home visits combined with telephone calls on medication adherence and quality of life in HIV-infected heroin users in Hunan of China. J Clin Nurs (2010) 1.20
Brugia malayi microfilariae induce cell death in human dendritic cells, inhibit their ability to make IL-12 and IL-10, and reduce their capacity to activate CD4+ T cells. J Immunol (2003) 1.19
Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011. Blood (2005) 1.19
Tissue responses to thermally-responsive hydrogel nanoparticles. J Biomater Sci Polym Ed (2004) 1.19
Pigmented paraganglioma of the kidney: a case report. Diagn Pathol (2012) 1.18
MicroRNA-7a regulates pancreatic β cell function. J Clin Invest (2014) 1.18
CYLD regulates angiogenesis by mediating vascular endothelial cell migration. Blood (2010) 1.17
Quantitative spectroscopic diffuse optical tomography of the breast guided by imperfect a priori structural information. Phys Med Biol (2005) 1.17
Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer. Cancer Res (2004) 1.17
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma. Clin Cancer Res (2009) 1.17
Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils. Immunity (2012) 1.17
Dietary resistant starch increases hypothalamic POMC expression in rats. Obesity (Silver Spring) (2008) 1.16
CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes. Arthritis Res Ther (2006) 1.15
CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formation. Proc Natl Acad Sci U S A (2014) 1.15
Treatment of chronic prostatitis in Chinese men. Asian J Androl (2009) 1.15
Piezoelectric and semiconducting coupled power generating process of a single ZnO belt/wire. A technology for harvesting electricity from the environment. Nano Lett (2006) 1.14
Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity. Am J Physiol Renal Physiol (2011) 1.13
Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner. Protein Cell (2011) 1.12
Rational design of the microtubule-targeting anti-breast cancer drug EM015. Cancer Res (2006) 1.11