Douglas L Feinstein

Author PubWeight™ 72.15‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity. Reg Anesth Pain Med 2003 3.87
2 Lipid emulsion is superior to vasopressin in a rodent model of resuscitation from toxin-induced cardiac arrest. Crit Care Med 2009 3.56
3 Lipid infusion accelerates removal of bupivacaine and recovery from bupivacaine toxicity in the isolated rat heart. Reg Anesth Pain Med 2006 2.74
4 Epinephrine impairs lipid resuscitation from bupivacaine overdose: a threshold effect. Anesthesiology 2009 2.11
5 Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. J Neurochem 2007 1.61
6 Locus coeruleus damage and noradrenaline reductions in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain 2011 1.50
7 Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. J Neurosci 2002 1.46
8 p38 MAPK-mediated transcriptional activation of inducible nitric-oxide synthase in glial cells. Roles of nuclear factors, nuclear factor kappa B, cAMP response element-binding protein, CCAAT/enhancer-binding protein-beta, and activating transcription factor-2. J Biol Chem 2002 1.38
9 Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. J Neuroimmunol 2005 1.29
10 Resuscitation with lipid versus epinephrine in a rat model of bupivacaine overdose. Anesthesiology 2008 1.28
11 Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. J Neurosci 2009 1.22
12 A novel fluorescent probe that is brain permeable and selectively binds to myelin. J Histochem Cytochem 2006 1.19
13 The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1. ASN Neuro 2011 1.19
14 Peroxisome proliferator-activated receptor gamma thiazolidinedione agonists increase glucose metabolism in astrocytes. J Biol Chem 2002 1.18
15 Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment. Mol Pharmacol 2006 1.14
16 P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis. J Neuroinflammation 2008 1.12
17 Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiol Aging 2006 1.11
18 The clinical course of experimental autoimmune encephalomyelitis is associated with a profound and sustained transcriptional activation of the genes encoding toll-like receptor 2 and CD14 in the mouse CNS. Brain Pathol 2002 1.10
19 Identification of complement 5a-like receptor (C5L2) from astrocytes: characterization of anti-inflammatory properties. J Neurochem 2005 1.10
20 The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes. J Neuroinflammation 2011 1.05
21 The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis. J Neurochem 2006 1.04
22 Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. J Leukoc Biol 2003 1.04
23 Inhibition of microglial inflammatory responses by norepinephrine: effects on nitric oxide and interleukin-1beta production. J Neuroinflammation 2004 1.03
24 The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease. Neurobiol Aging 2011 1.03
25 mTOR kinase, a key player in the regulation of glial functions: relevance for the therapy of multiple sclerosis. Glia 2012 1.02
26 Effect of pioglitazone treatment in a patient with secondary multiple sclerosis. J Neuroinflammation 2004 1.00
27 A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease. Curr Alzheimer Res 2009 0.99
28 Neuroprotective actions of noradrenaline: effects on glutathione synthesis and activation of peroxisome proliferator activated receptor delta. J Neurochem 2007 0.98
29 Effect of pioglitazone treatment on behavioral symptoms in autistic children. J Neuroinflammation 2007 0.95
30 Norepinephrine protects cortical neurons against microglial-induced cell death. J Neurosci Res 2005 0.94
31 Increasing CNS noradrenaline reduces EAE severity. J Neuroimmune Pharmacol 2009 0.93
32 The role of the glia limitans in ADP-induced pial arteriolar relaxation in intact and ovariectomized female rats. Am J Physiol Heart Circ Physiol 2004 0.92
33 Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. Neurochem Res 2004 0.92
34 Epinephrine induces rapid deterioration in pulmonary oxygen exchange in intact, anesthetized rats: a flow and pulmonary capillary pressure-dependent phenomenon. Anesthesiology 2012 0.91
35 A pilot test of pioglitazone as an add-on in patients with relapsing remitting multiple sclerosis. J Neuroimmunol 2009 0.91
36 Modulation of inducible nitric oxide synthase expression by sumoylation. J Neuroinflammation 2009 0.91
37 Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. J Neurochem 2003 0.90
38 Estrogen inhibits NF kappa B-dependent inflammation in brain endothelium without interfering with I kappa B degradation. Neuroreport 2002 0.89
39 Intrinsic regulation of brain inflammatory responses. Cell Mol Neurobiol 2003 0.88
40 Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576. Neuropharmacology 2005 0.86
41 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway. J Neurochem 2006 0.86
42 Norepinephrine increases I kappa B alpha expression in astrocytes. J Biol Chem 2002 0.85
43 Prolonged survival of mice with established intracerebral glioma receiving combined treatment with peroxisome proliferator-activated receptor-gamma thiazolidinedione agonists and interleukin-2-secreting syngeneic/allogeneic fibroblasts. J Neurosurg 2007 0.85
44 Effects of pioglitazone on diffusion tensor imaging indices in multiple sclerosis patients. Neurosci Lett 2010 0.84
45 Effects of noradrenaline on neuronal NOS2 expression and viability. Antioxid Redox Signal 2006 0.84
46 Regulation of MCP-1 production in brain by stress and noradrenaline-modulating drugs. J Neurochem 2010 0.83
47 Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised. J Neuroinflammation 2004 0.83
48 Sildenafil (Viagra) ameliorates clinical symptoms and neuropathology in a mouse model of multiple sclerosis. Acta Neuropathol 2011 0.83
49 Beta-amyloid-dependent expression of NOS2 in neurons: prevention by an alpha2-adrenergic antagonist. Antioxid Redox Signal 2006 0.83
50 Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem 2003 0.82
51 Development of amyloid burden in African Green monkeys. Neurobiol Aging 2013 0.82
52 Intraosseous lipid emulsion: an effective alternative to IV delivery in emergency situations. Crit Care Med 2014 0.81
53 Degeneration of noradrenergic fibres from the locus coeruleus causes tight-junction disorganisation in the rat brain. Eur J Neurosci 2006 0.81
54 Differential effects of PPARgamma agonists on the metabolic properties of gliomas and astrocytes. Neurosci Lett 2007 0.81
55 Adding bupivacaine to high-potassium cardioplegia improves function and reduces cellular damage of rat isolated hearts after prolonged, cold storage. Anesthesiology 2006 0.80
56 Brodifacoum induces early hemoglobinuria and late hematuria in rats: novel rapid biomarkers of poisoning. Am J Nephrol 2015 0.80
57 Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. J Neurosci Res 2002 0.79
58 Regulation of oligodendrocyte progenitor cell maturation by PPARδ: effects on bone morphogenetic proteins. ASN Neuro 2010 0.78
59 Pioglitazone attenuates acute cocaine toxicity in rat isolated heart: potential protection by metabolic modulation. Anesthesiology 2011 0.78
60 Altering mitochondrial dysfunction as an approach to treating Alzheimer's disease. Adv Pharmacol 2012 0.77
61 The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus. J Neurochem 2012 0.77
62 The novel HSP90 inhibitor, PU-H71, suppresses glial cell activation but weakly affects clinical signs of EAE. J Neuroimmunol 2012 0.77
63 Dimethyl fumarate regulates histone deacetylase expression in astrocytes. J Neuroimmunol 2013 0.77
64 Sevoflurane reduces clinical disease in a mouse model of multiple sclerosis. J Neuroinflammation 2012 0.76
65 Beneficial effects of blueberries in experimental autoimmune encephalomyelitis. J Agric Food Chem 2012 0.76
66 PPAR-gamma Thiazolidinedione Agonists and Immunotherapy in the Treatment of Brain Tumors. PPAR Res 2008 0.76
67 IgM to S-nitrosylated protein is found intrathecally in relapsing-remitting multiple sclerosis. J Neuroimmunol 2013 0.75
68 Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease. Neurology 2008 0.75
69 Effects of peptide fraction and counter ion on the development of clinical signs in experimental autoimmune encephalomyelitis. J Neurochem 2014 0.75
70 NO and glial cell biology. Antioxid Redox Signal 2006 0.75