Mark D Biggin

Author PubWeight™ 55.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm. PLoS Biol 2008 6.30
2 A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm. Cell 2008 5.63
3 Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions. Genome Biol 2009 5.23
4 Large-scale turnover of functional transcription factor binding sites in Drosophila. PLoS Comput Biol 2006 4.01
5 Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline. Genome Biol 2006 3.22
6 NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila. Mol Cell Biol 2008 3.11
7 Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome. Chromosoma 2007 2.73
8 The role of chromatin accessibility in directing the widespread, overlapping patterns of Drosophila transcription factor binding. Genome Biol 2011 2.68
9 Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development. PLoS Genet 2011 2.65
10 Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species. PLoS Biol 2010 2.32
11 Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution II: dynamics. Genome Biol 2006 2.09
12 Dynamic reprogramming of chromatin accessibility during Drosophila embryo development. Genome Biol 2011 1.61
13 DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila. Proc Natl Acad Sci U S A 2012 1.39
14 A conserved developmental patterning network produces quantitatively different output in multiple species of Drosophila. PLoS Genet 2011 1.17
15 Zeste maintains repression of Ubx transgenes: support for a new model of Polycomb repression. Development 2002 1.16
16 Visual exploration of three-dimensional gene expression using physical views and linked abstract views. IEEE/ACM Trans Comput Biol Bioinform 2009 1.14
17 Integrating data clustering and visualization for the analysis of 3D gene expression data. IEEE/ACM Trans Comput Biol Bioinform 2010 1.03
18 Automatic channel unmixing for high-throughput quantitative analysis of fluorescence images. Opt Express 2007 0.97
19 A "tagless" strategy for identification of stable protein complexes genome-wide by multidimensional orthogonal chromatographic separation and iTRAQ reagent tracking. J Proteome Res 2008 0.88
20 Octomeric pyruvate-ferredoxin oxidoreductase from Desulfovibrio vulgaris. J Struct Biol 2007 0.88
21 Automated iterative MS/MS acquisition: a tool for improving efficiency of protein identification using a LC-MALDI MS workflow. Anal Chem 2011 0.88
22 High-throughput SELEX determination of DNA sequences bound by transcription factors in vitro. Methods Mol Biol 2012 0.88
23 Survey of large protein complexes in D. vulgaris reveals great structural diversity. Proc Natl Acad Sci U S A 2009 0.86
24 Nonparametric identification of regulatory interactions from spatial and temporal gene expression data. BMC Bioinformatics 2010 0.81
25 High-throughput isolation and characterization of untagged membrane protein complexes: outer membrane complexes of Desulfovibrio vulgaris. J Proteome Res 2012 0.80
26 Genome-wide in vivo cross-linking of sequence-specific transcription factors. Methods Mol Biol 2012 0.80
27 Building quantitative, three-dimensional atlases of gene expression and morphology at cellular resolution. Wiley Interdiscip Rev Dev Biol 2013 0.79
28 Coupling visualization and data analysis for knowledge discovery from multi-dimensional scientific data. Procedia Comput Sci 2010 0.78
29 Quantitative models of the mechanisms that control genome-wide patterns of animal transcription factor binding. Methods Cell Biol 2012 0.76
30 A multichannel gel electrophoresis and continuous fraction collection apparatus for high-throughput protein separation and characterization. Methods Mol Biol 2012 0.75
31 Nonparametric variable selection and modeling for spatial and temporal regulatory networks. Methods Cell Biol 2012 0.75
32 A multichannel gel electrophoresis and continuous fraction collection apparatus for high-throughput protein separation and characterization. Electrophoresis 2010 0.75