Neuroinflammation and the plasticity-related immediate-early gene Arc.

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The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes. Proc Natl Acad Sci U S A (2002) 1.66

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Neuroinflammation alters the hippocampal pattern of behaviorally induced Arc expression. J Neurosci (2005) 1.64

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A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proc Natl Acad Sci U S A (2003) 1.38

Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol Aging (2006) 1.37

Sustained hippocampal IL-1beta overexpression impairs contextual and spatial memory in transgenic mice. Brain Behav Immun (2009) 1.36

Inflammation regulates functional integration of neurons born in adult brain. J Neurosci (2008) 1.35

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Effector immediate-early gene arc in the amygdala plays a critical role in alcoholism. J Neurosci (2008) 1.32

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Imaging neural activity with temporal and cellular resolution using FISH. Curr Opin Neurobiol (2001) 1.26

Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat. Neuroscience (2006) 1.24

Accuracy of hippocampal network activity is disrupted by neuroinflammation: rescue by memantine. Brain (2009) 1.20

Links between innate immunity and normal tissue radiobiology. Radiat Res (2010) 1.19

Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures. J Neurosci (2005) 1.19

Chronic brain inflammation leads to a decline in hippocampal NMDA-R1 receptors. J Neuroinflammation (2004) 1.17

IL-1RA blocks E. coli-induced suppression of Arc and long-term memory in aged F344xBN F1 rats. Brain Behav Immun (2009) 1.15

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Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons. J Neurochem (2007) 0.97

Trauma-induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation. Hippocampus (2010) 0.96