Published in Trends Neurosci on September 30, 2011
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Social information embedded in vocalizations induces neurogenomic and behavioral responses. PLoS One (2014) 0.75
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Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268. J Neurosci (2001) 2.97
Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J Neurosci (2002) 2.94
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. Neuron (2006) 2.79
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The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Cell (2007) 2.72
Spatial exploration-induced Arc mRNA and protein expression: evidence for selective, network-specific reactivation. J Neurosci (2005) 2.69
Selective targeting of newly synthesized Arc mRNA to active synapses requires NMDA receptor activation. Neuron (2001) 2.67
The actin cytoskeleton: integrating form and function at the synapse. Annu Rev Neurosci (2005) 2.60
Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus in vivo. J Neurosci (2007) 2.57
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Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation. J Neurosci (2001) 2.44
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In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. Cell (2006) 2.28
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Key role for gene dosage and synaptic homeostasis in autism spectrum disorders. Trends Genet (2010) 2.14
Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons. Proc Natl Acad Sci U S A (2008) 2.13
Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. J Neurosci (2005) 1.79
The activity-regulated cytoskeletal-associated protein (Arc/Arg3.1) is required for memory consolidation of pavlovian fear conditioning in the lateral amygdala. J Neurosci (2008) 1.74
Experience-dependent structural plasticity in the cortex. Trends Neurosci (2011) 1.73
AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc. Nat Neurosci (2006) 1.72
The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. J Neurosci (2009) 1.69
The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomes. Proc Natl Acad Sci U S A (2002) 1.66
Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiol Aging (2010) 1.61
Arc-dependent synapse-specific homeostatic plasticity. Proc Natl Acad Sci U S A (2010) 1.56
A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites. Proc Natl Acad Sci U S A (2001) 1.53
Novel translational control in Arc-dependent long term potentiation consolidation in vivo. J Biol Chem (2009) 1.52
Arc regulates spine morphology and maintains network stability in vivo. Proc Natl Acad Sci U S A (2010) 1.51
MAL and ternary complex factor use different mechanisms to contact a common surface on the serum response factor DNA-binding domain. Mol Cell Biol (2006) 1.50
Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron (2011) 1.49
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Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation. Nat Neurosci (2010) 1.48
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Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II. Nat Neurosci (2011) 1.39
Multiplexed dendritic targeting of alpha calcium calmodulin-dependent protein kinase II, neurogranin, and activity-regulated cytoskeleton-associated protein RNAs by the A2 pathway. Mol Biol Cell (2008) 1.35
Actin polymerization and ERK phosphorylation are required for Arc/Arg3.1 mRNA targeting to activated synaptic sites on dendrites. J Neurosci (2007) 1.35
Effector immediate-early gene arc in the amygdala plays a critical role in alcoholism. J Neurosci (2008) 1.32
The tumor suppressor Pml regulates cell fate in the developing neocortex. Nat Neurosci (2009) 1.30
Acquisition of a novel behavior induces higher levels of Arc mRNA than does overtrained performance. Neuroscience (2002) 1.26
Dynamics of bidirectional transport of Arc mRNA in neuronal dendrites. J Comp Neurol (2007) 1.22
Long-term potentiation in the rat dentate gyrus is associated with enhanced Arc/Arg3.1 protein expression in spines, dendrites and glia. Eur J Neurosci (2005) 1.22
Remodelling of synaptic morphology but unchanged synaptic density during late phase long-term potentiation (LTP): a serial section electron micrograph study in the dentate gyrus in the anaesthetised rat. Neuroscience (2004) 1.20
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