Host-derived diagnostic markers related to soft tissue destruction and bone degradation in periodontitis.

PubWeight™: 2.11‹?› | Rank: Top 2%

🔗 View Article (PMID 21323706)

Published in J Clin Periodontol on March 01, 2011

Authors

Nurcan Buduneli1, Denis F Kinane

Author Affiliations

1: Department of Periodontology, School of Dentistry, Ege University, Izmir, Turkey. nurcan.buduneli@ege.edu.tr

Associated clinical trials:

Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients. (MMP-8) | NCT04605289

Articles citing this

Serum, saliva, and GCF concentration of RANKL and osteoprotegerin in smokers versus nonsmokers with chronic periodontitis. Adv Biomed Res (2016) 1.38

Bone remodeling-associated salivary biomarker MIP-1α distinguishes periodontal disease from health. J Periodontal Res (2011) 0.95

Novel protein identification methods for biomarker discovery via a proteomic analysis of periodontally healthy and diseased gingival crevicular fluid samples. J Clin Periodontol (2011) 0.95

Host response mechanisms in periodontal diseases. J Appl Oral Sci (2015) 0.90

A randomized controlled trial of pre-conception treatment for periodontal disease to improve periodontal status during pregnancy and birth outcomes. BMC Pregnancy Childbirth (2013) 0.85

A cross-sectional assessment of biomarker levels around implants versus natural teeth in periodontal maintenance patients. J Periodontol (2014) 0.83

Oral fluid based biomarkers in periodontal disease: part 1. Saliva. J Int Oral Health (2014) 0.82

Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines. PLoS One (2015) 0.80

Effect of nonsurgical periodontal treatment in conjunction with either systemic administration of amoxicillin and metronidazole or additional photodynamic therapy on the concentration of matrix metalloproteinases 8 and 9 in gingival crevicular fluid in patients with aggressive periodontitis. BMC Oral Health (2015) 0.80

MMP activation in diagnostics of periodontitis and systemic inflammation. J Clin Periodontol (2011) 0.80

Inflammatory Mediators of Leprosy Reactional Episodes and Dental Infections: A Systematic Review. Mediators Inflamm (2015) 0.80

A clinical guide to periodontology: pathology of periodontal disease. Br Dent J (2014) 0.79

Salivary soluble receptor activator of nuclear factor kappa B ligand/osteoprotegerin ratio in periodontal disease and health. J Periodontal Implant Sci (2013) 0.79

CD14 and TNFα single nucleotide polymorphisms are candidates for genetic biomarkers of peri-implantitis. Clin Oral Investig (2014) 0.78

The landscape of protein biomarkers proposed for periodontal disease: markers with functional meaning. Biomed Res Int (2014) 0.78

Discovery of biomarker combinations that predict periodontal health or disease with high accuracy from GCF samples based on high-throughput proteomic analysis and mixed-integer linear optimization. J Clin Periodontol (2012) 0.78

Host modulation in rheumatoid arthritis patients with TNF blockers significantly decreases biochemical parameters in periodontitis. Inflammation (2013) 0.78

Protein biomarkers of periodontitis in saliva. ISRN Inflamm (2014) 0.78

Patient-Specific Variations in Biomarkers across Gingivitis and Periodontitis. PLoS One (2015) 0.78

Interlinking Periodontitis and Type 2 Diabetes Mellitus by Assessment of Crevicular Visfatin Levels in Health and in Disease Before and After Initial Periodontal Therapy. J Clin Diagn Res (2016) 0.77

Adjunctive effect of antimicrobial photodynamic therapy to nonsurgical periodontal treatment in smokers: a randomized clinical trial. Lasers Med Sci (2013) 0.77

Analysis of matrix metalloproteinase-8 levels in gingival crevicular fluid and whole mouth fluid among smokers and nonsmokers using enzyme-linked immune-sorbent assay and a novel chair-side test. J Indian Soc Periodontol (2015) 0.77

Clinical improvement following therapy for periodontitis: Association with a decrease in IL-1 and IL-6. Exp Ther Med (2014) 0.76

The salivary β-HEX A% index as an excellent marker of periodontitis in smoking alcohol-dependent persons. Dis Markers (2013) 0.76

Lessons from Microglia Aging for the Link between Inflammatory Bone Disorders and Alzheimer's Disease. J Immunol Res (2015) 0.76

Biochemical markers as predictors of bone remodelling in dental disorders: a narrative description of literature. Clin Cases Miner Bone Metab (2012) 0.76

Effect of periodontal surgery on osteoprotegerin levels in gingival crevicular fluid, saliva, and gingival tissues of chronic periodontitis patients. Dis Markers (2015) 0.76

Milk fat globule epidermal growth factor 8 inhibits periodontitis in non-human primates and its gingival crevicular fluid levels can differentiate periodontal health from disease in humans. J Clin Periodontol (2017) 0.75

The role of smoking and gingival crevicular fluid markers on coronally advanced flap outcomes. J Periodontol (2013) 0.75

The Effect of Photodynamic Therapy and Diode Laser as Adjunctive Periodontal Therapy on the Inflammatory Mediators Levels in Gingival Crevicular Fluid and Clinical Periodontal Status. J Dent (Shiraz) (2016) 0.75

Hepatocyte growth factor levels in the saliva and gingival crevicular fluid in smokers with periodontitis. Dis Markers (2014) 0.75

Identification of Gingival Crevicular Fluid Sampling, Analytical Methods, and Oral Biomarkers for the Diagnosis and Monitoring of Periodontal Diseases: A Systematic Review. Dis Markers (2016) 0.75

Genes related to inflammation and bone loss process in periodontitis suggested by bioinformatics methods. BMC Oral Health (2015) 0.75

Correlation of salivary immunoglobulin A against lipopolysaccharide of Porphyromonas gingivalis with clinical periodontal parameters. Contemp Clin Dent (2015) 0.75

Rapid assessment of salivary MMP-8 and periodontal disease using lateral flow immunoassay. Oral Dis (2016) 0.75

Matrix Metalloproteinases as Regulators of Periodontal Inflammation. Int J Mol Sci (2017) 0.75

sIgA, peroxidase and collagenase in saliva of smokers aggressive periodontal patients. J Oral Biol Craniofac Res (2016) 0.75

Salivary Visfatin Concentration in Response to Non-surgical Periodontal Therapy. J Clin Diagn Res (2015) 0.75

A novel method of sampling gingival crevicular fluid from a mouse model of periodontitis. J Immunol Methods (2016) 0.75

Oral fluid-based biomarkers in periodontal disease - part 2. Gingival crevicular fluid. J Int Oral Health (2014) 0.75

Is there an association between obstructive sleep apnea syndrome and periodontal inflammation? Clin Oral Investig (2015) 0.75

Articles by these authors

Use of saliva-based nano-biochip tests for acute myocardial infarction at the point of care: a feasibility study. Clin Chem (2009) 1.51

IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta. J Immunol (2008) 1.36

Modulation of TLR2 protein expression by miR-105 in human oral keratinocytes. J Biol Chem (2009) 1.35

Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis. J Periodontal Res (2003) 1.16

Differential activation of human gingival epithelial cells and monocytes by Porphyromonas gingivalis fimbriae. Infect Immun (2006) 1.16

In vitro modeling of host-parasite interactions: the 'subgingival' biofilm challenge of primary human epithelial cells. BMC Microbiol (2009) 1.15

Interleukin-1beta modulates proinflammatory cytokine production in human epithelial cells. Infect Immun (2008) 1.15

Periodontal health and systemic disorders. J Can Dent Assoc (2002) 1.11

Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2. J Immunol (2009) 1.06

Parotid secretory protein is expressed and inducible in human gingival keratinocytes. J Periodontal Res (2005) 1.06

Epithelial cell pro-inflammatory cytokine response differs across dental plaque bacterial species. J Clin Periodontol (2010) 1.05

Effect of genetic variability on the inflammatory response to periodontal infection. J Clin Periodontol (2005) 1.04

The role of glycogen synthase kinase 3 in regulating IFN-β-mediated IL-10 production. J Immunol (2010) 1.02

Influence of periodontal disease, Porphyromonas gingivalis and cigarette smoking on systemic anti-citrullinated peptide antibody titres. J Clin Periodontol (2013) 1.02

Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism. BMC Microbiol (2009) 1.00

Adipokines and inflammatory mediators after initial periodontal treatment in patients with type 2 diabetes and chronic periodontitis. J Periodontol (2010) 0.99

TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells. Eur J Immunol (2008) 0.99

Innate cellular responses to the periodontal biofilm. Front Oral Biol (2011) 0.98

Effects of smoking and gingival inflammation on salivary antioxidant capacity. J Clin Periodontol (2006) 0.96

Porphyromonas gingivalis enhances FasL expression via up-regulation of NFkappaB-mediated gene transcription and induces apoptotic cell death in human gingival epithelial cells. Microbiology (2006) 0.95

Saliva concentrations of RANKL and osteoprotegerin in smoker versus non-smoker chronic periodontitis patients. J Clin Periodontol (2008) 0.94

Nonsurgical mechanical treatment strategies for periodontal disease. Dent Clin North Am (2010) 0.93

Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes. Mol Immunol (2010) 0.90

Is periodontitis associated with an increased risk of coronary heart disease and preterm and/or low birth weight births? J Clin Periodontol (2002) 0.89

Salivary antioxidants in patients with type 1 or 2 diabetes and inflammatory periodontal disease: a case-control study. J Periodontol (2009) 0.89

Periodontal therapy in chronic periodontitis lowers gingival crevicular fluid interleukin-1beta and DAS28 in rheumatoid arthritis patients. Rheumatol Int (2013) 0.88

Childhood obesity and skeletal maturation assessed with Fishman's hand-wrist analysis. Am J Orthod Dentofacial Orthop (2007) 0.88

Nutrition, inflammation, and periodontal disease. Nutrition (2003) 0.87

P. gingivalis modulates keratinocytes through FOXO transcription factors. PLoS One (2013) 0.86

Sphingosine 1-phosphate 1 and TLR4 mediate IFN-beta expression in human gingival epithelial cells. J Immunol (2008) 0.86

Antigenic experience dictates functional role of glycogen synthase kinase-3 in human CD4+ T cell responses. J Immunol (2008) 0.85

Gingival crevicular fluid IL-6, tPA, PAI-2, albumin levels following initial periodontal treatment in chronic periodontitis patients with or without type 2 diabetes. Inflamm Res (2010) 0.85

c-jun controls the ability of IL-12 to induce IL-10 production from human memory CD4+ T cells. J Immunol (2009) 0.85

Macrophage inflammatory protein-3alpha and beta-defensin-2 stimulate dentin sialophosphoprotein gene expression in human pulp cells. Biochem Biophys Res Commun (2003) 0.84

Porphyromonas gingivalis influences actin degradation within epithelial cells during invasion and apoptosis. Cell Microbiol (2012) 0.84

Interleukin-17, RANKL, and osteoprotegerin levels in gingival crevicular fluid from smoking and non-smoking patients with chronic periodontitis during initial periodontal treatment. J Periodontol (2009) 0.84

Host response in aggressive periodontitis. Periodontol 2000 (2014) 0.84

Plasminogen activator system in smokers and non-smokers with and without periodontal disease. J Clin Periodontol (2005) 0.83

Neutrophils rescue gingival epithelial cells from bacterial-induced apoptosis. J Leukoc Biol (2009) 0.81

Polymicrobial infections, biofilms, and beyond. J Clin Periodontol (2009) 0.80

Systemic low-dose doxycycline and alendronate administration and serum interleukin-1beta, osteocalcin, and C-reactive protein levels in rats. J Periodontol (2005) 0.79

Dietary supplementation of omega-3 fatty acid and circulating levels of interleukin-1beta, osteocalcin, and C-reactive protein in rats. J Periodontol (2006) 0.79

Immunohistochemical evaluation of Ki-67 expression and apoptosis in cyclosporin A-induced gingival overgrowth. J Periodontol (2007) 0.78

Seventh European Workshop on Periodontology of the European Academy of Periodontology at the Parador at la Granja, Segovia, Spain. J Clin Periodontol (2011) 0.76

Reducing variability and choosing ideal subjects for experimental gingivitis studies. J Clin Periodontol (2005) 0.76

Sphingosine kinase-1 is required for toll mediated beta-defensin 2 induction in human oral keratinocytes. PLoS One (2010) 0.76

Single-visit, full-mouth ultrasonic debridement: a paradigm shift in periodontal therapy? J Clin Periodontol (2005) 0.75

Letter of welcome: 2004 Annual Scientific Meeting of the International Society for the Prevention of Tobacco Induced Diseases. Tob Induc Dis (2004) 0.75

Effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on serum interleukin-1beta, osteocalcin, and C-reactive protein levels in rats. J Periodontol (2006) 0.75

Denis F. Kinane, BDS, PhD. A conversation with the new dean of Penn Dental Medicine. Penn Dent J (Phila) (2009) 0.75

Sixth European Workshop on Periodontology of the European Academy of Periodontology at the Charterhouse at Ittingen, Thurgau, Switzerland. J Clin Periodontol (2008) 0.75