Published in Bioeng Bugs on January 12, 2010
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J Mol Biol (1986) 55.34
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res (1997) 13.15
Molecular biology of the LysR family of transcriptional regulators. Annu Rev Microbiol (1993) 10.30
Arac/XylS family of transcriptional regulators. Microbiol Mol Biol Rev (1997) 6.56
Strategies for achieving high-level expression of genes in Escherichia coli. Microbiol Rev (1996) 4.93
Recombinant protein expression in Escherichia coli. Curr Opin Biotechnol (1999) 4.59
Promoters responsive to DNA bending: a common theme in prokaryotic gene expression. Microbiol Rev (1994) 3.81
Tumor-targeted Salmonella as a novel anticancer vector. Cancer Res (1997) 3.45
Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells. Cell (1988) 3.29
The extracytoplasmic function sigma factors: role and regulation. Mol Microbiol (1998) 3.13
Genetics of naphthalene catabolism in pseudomonads. Crit Rev Microbiol (1988) 2.87
Controlling basal expression in an inducible T7 expression system by blocking the target T7 promoter with lac repressor. J Mol Biol (1991) 2.66
Altered effector specificities in regulators of gene expression: TOL plasmid xylS mutants and their use to engineer expansion of the range of aromatics degraded by bacteria. Proc Natl Acad Sci U S A (1986) 2.57
Transcription attenuation: a highly conserved regulatory strategy used by bacteria. Trends Genet (2005) 2.52
Transcriptional control of the Pseudomonas putida TOL plasmid catabolic pathways. Mol Microbiol (1993) 2.11
A new family of sugar-inducible expression vectors for Escherichia coli. Protein Eng (1991) 2.11
Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria. Plasmid (1997) 2.08
Anti-sigma factors. Curr Opin Microbiol (1999) 1.83
Aspirin. Sci Am (1991) 1.81
Bacteria as tumour-targeting vectors. Lancet Oncol (2003) 1.78
In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit. Nat Methods (2007) 1.64
Information processing by RNA polymerase: recognition of regulatory signals during RNA chain elongation. J Bacteriol (1998) 1.63
AraC-XylS database: a family of positive transcriptional regulators in bacteria. Nucleic Acids Res (2002) 1.61
Transcriptional induction kinetics from the promoters of the catabolic pathways of TOL plasmid pWW0 of Pseudomonas putida for metabolism of aromatics. J Bacteriol (1994) 1.60
Gene-expression tools for the metabolic engineering of bacteria. Trends Biotechnol (1999) 1.56
Processive antitermination. J Bacteriol (1999) 1.52
Tight transcriptional control mechanism ensures stable high-level expression from T7 promoter-based expression plasmids. Biotechnology (N Y) (1995) 1.26
Protein-induced bending as a transcriptional switch. Science (1993) 1.22
Effector specificity mutants of the transcriptional activator NahR of naphthalene degrading Pseudomonas define protein sites involved in binding of aromatic inducers. J Biol Chem (1997) 1.21
Transcription attenuation. Biochim Biophys Acta (2002) 1.20
Parameters affecting gene expression from the Pm promoter in gram-negative bacteria. Metab Eng (2000) 1.15
Genetic design for facilitated production and recovery of recombinant proteins in Escherichia coli. Biotechnol Appl Biochem (2002) 1.10
Leucines 193 and 194 at the N-terminal domain of the XylS protein, the positive transcriptional regulator of the TOL meta-cleavage pathway, are involved in dimerization. J Bacteriol (2003) 1.03
Pm promoter expression mutants and their use in broad-host-range RK2 plasmid vectors. Metab Eng (2000) 1.02
Comparison of repressor and transcriptional attenuator systems for control of amino acid biosynthetic operons. J Mol Biol (2001) 1.00
Genetic evidence that the XylS regulator of the Pseudomonas TOL meta operon controls the Pm promoter through weak DNA-protein interactions. J Bacteriol (1994) 0.96
Rational design of a bacterial transcriptional cascade for amplifying gene expression capacity. Nucleic Acids Res (2001) 0.95
Improvement of recombinant protein yield by a combination of transcriptional amplification and stabilization of gene expression. Appl Environ Microbiol (2002) 0.94
Roles of effectors in XylS-dependent transcription activation: intramolecular domain derepression and DNA binding. J Bacteriol (2008) 0.91
Construction and characterization of a novel cross-regulation system for regulating cloned gene expression in Escherichia coli. Gene (1993) 0.85
XylS-Pm promoter interactions through two helix-turn-helix motifs: identifying XylS residues important for DNA binding and activation. J Mol Biol (2007) 0.85
Stable long-term indigo production by overexpression of dioxygenase genes using a chromosomal integrated cascade expression circuit. J Biotechnol (2004) 0.84
A new generation of vectors with increased induction ratios by overimposing a second regulatory level by attenuation. Nucleic Acids Res (2005) 0.84
Stringent regulation and high-level expression of heterologous genes in Escherichia coli using T7 system controllable by the araBAD promoter. Biotechnol Prog (2002) 0.80
Expression in bacteria of small and specific protein domains of two transcription factor isoforms, purification and monospecific polyclonal antibodies generation, by a two-step affinity chromatography procedure. Protein Expr Purif (2008) 0.77
Pathogens on aspirin: promising research and therapeutic applications. Nat Methods (2007) 0.76
Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host Microbe (2009) 2.58
The viable but nonculturable state and starvation are different stress responses of Enterococcus faecalis, as determined by proteome analysis. J Bacteriol (2002) 1.35
The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae. BMC Genomics (2008) 1.34
Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice. PLoS One (2010) 1.29
Signatures of human regulatory T cells: an encounter with old friends and new players. Genome Biol (2006) 1.27
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice. Am J Pathol (2009) 1.18
HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2. Proc Natl Acad Sci U S A (2012) 1.15
Intranasal immunization promotes th17 immune responses. J Immunol (2009) 1.14
Novel conserved group A streptococcal proteins identified by the antigenome technology as vaccine candidates for a non-M protein-based vaccine. Infect Immun (2010) 1.04
Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice. Vaccine (2011) 1.04
Lactoferrin impairs type III secretory system function in enteropathogenic Escherichia coli. Infect Immun (2003) 1.03
HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype. Proc Natl Acad Sci U S A (2008) 0.98
Human milk secretory antibodies against attaching and effacing Escherichia coli antigens. Emerg Infect Dis (2003) 0.97
Bone morphogenetic protein 15 (BMP15) alleles predict over-response to recombinant follicle stimulation hormone and iatrogenic ovarian hyperstimulation syndrome (OHSS). Pharmacogenet Genomics (2006) 0.94
Gene expression signatures of peripheral CD4+ T cells clearly discriminate between patients with acute and chronic hepatitis B infection. Hepatology (2009) 0.93
Opacity factor activity and epithelial cell binding by the serum opacity factor protein of Streptococcus pyogenes are functionally discrete. J Biol Chem (2008) 0.92
Pidotimod promotes functional maturation of dendritic cells and displays adjuvant properties at the nasal mucosa level. Int Immunopharmacol (2009) 0.91
Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice. Microbes Infect (2008) 0.90
The synthetic TLR2 agonist BPPcysMPEG leads to efficient cross-priming against co-administered and linked antigens. Eur J Immunol (2010) 0.89
HIV-1 matrix protein p17 binds to monocytes and selectively stimulates MCP-1 secretion: role of transcriptional factor AP-1. Cell Microbiol (2007) 0.88
HLA-universal platelet transfusions prevent platelet refractoriness in a mouse model. Hum Gene Ther (2013) 0.88
Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. J Clin Immunol (2011) 0.87
Simian immunodeficiency virus and human immunodeficiency virus type 1 matrix proteins specify different capabilities to modulate B cell growth. J Virol (2014) 0.86
HIV-1 matrix protein p17 promotes lymphangiogenesis and activates the endothelin-1/endothelin B receptor axis. Arterioscler Thromb Vasc Biol (2014) 0.85
A Toll-like receptor 2/6 agonist reduces allergic airway inflammation in chronic respiratory sensitisation to Timothy grass pollen antigens. Int Arch Allergy Immunol (2009) 0.84
Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice. Hepatology (2012) 0.84
A prime-boost vaccination protocol optimizes immune responses against the nucleocapsid protein of the SARS coronavirus. Vaccine (2008) 0.82
Peritoneal cavity is dominated by IFNγ-secreting CXCR3+ Th1 cells. PLoS One (2011) 0.80
NKT cell stimulation with α-galactosylceramide results in a block of Th17 differentiation after intranasal immunization in mice. PLoS One (2012) 0.79
Modulation of chemokine gene expression by Shiga-toxin producing Escherichia coli belonging to various origins and serotypes. Microbes Infect (2007) 0.79
Vaccines based on Nef and on Nef/DeltaV2 Env. Microbes Infect (2005) 0.79
Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties. Sci Rep (2012) 0.79
Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility. J Gastroenterol Hepatol (2007) 0.78
Intranasal vaccination with a plant-derived H5 HA vaccine protects mice and ferrets against highly pathogenic avian influenza virus challenge. Hum Vaccin Immunother (2015) 0.77
HIV pseudovirion vaccine exposing Env "fusion intermediates"-response to immunisation in human CD4/CCR5-transgenic rats. Vaccine (2009) 0.77
The toll-like receptor 2/6 ligand MALP-2 reduces the viability of Mycobacterium tuberculosis in murine macrophages. Open Microbiol J (2009) 0.77
HIV-1 matrix protein p17 modulates in vivo preactivated murine T-cell response and enhances the induction of systemic and mucosal immunity against intranasally co-administered antigens. Viral Immunol (2006) 0.75
Pharmaceutical biotechnology. Curr Opin Biotechnol (2004) 0.75
Germline TP53 mutations and single nucleotide polymorphisms in children. Medicina (B Aires) (2009) 0.75
Replication-deficient mutant Herpes Simplex Virus-1 targets professional antigen presenting cells and induces efficient CD4+ T helper responses. Microbes Infect (2007) 0.75
Vaccines against Infections Caused by Salmonella, Shigella, and Pathogenic Escherichia coli. Ecosal Plus (2004) 0.75