Published in Biomaterials on February 21, 2011
Physical non-viral gene delivery methods for tissue engineering. Ann Biomed Eng (2012) 1.06
Dynamic topographical control of mesenchymal stem cells by culture on responsive poly(ε-caprolactone) surfaces. Adv Mater (2011) 0.91
Inorganic coatings for optimized non-viral transfection of stem cells. Sci Rep (2013) 0.87
Nanotopographical Modulation of Cell Function through Nuclear Deformation. ACS Appl Mater Interfaces (2016) 0.79
Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition. Sci Rep (2015) 0.78
Combining topographical and genetic cues to promote neuronal fate specification in stem cells. Biomacromolecules (2012) 0.76
3-D Scaffold Platform for Optimized Non-viral Transfection of Multipotent Stem Cells. J Mater Chem B Mater Biol Med (2014) 0.76
Surface-mediated nucleic acid delivery by lipoplexes prepared in microwell arrays. Small (2013) 0.75
Integrins regulate Rac targeting by internalization of membrane domains. Science (2004) 5.07
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med (2005) 4.04
Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. Biophys J (2007) 3.57
A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell (1998) 3.56
Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials (2005) 2.94
Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes. Mol Ther (2005) 2.72
Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res (2007) 2.46
Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography. Exp Cell Res (2003) 2.02
Lifeact mice for studying F-actin dynamics. Nat Methods (2010) 2.00
Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat Mater (2005) 1.83
Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein. Cell Motil Cytoskeleton (2001) 1.78
Intracellular trafficking of nonviral vectors. Gene Ther (2005) 1.78
Surface-tethered DNA complexes for enhanced gene delivery. Bioconjug Chem (2002) 1.70
Increasing fibroblast response to materials using nanotopography: morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands. Exp Cell Res (2002) 1.66
Effects of artificial micro- and nano-structured surfaces on cell behaviour. Ann Anat (2008) 1.66
A model for non-viral gene delivery: through syndecan adhesion molecules and powered by actin. J Gene Med (2004) 1.65
Cell shape regulates global histone acetylation in human mammary epithelial cells. Exp Cell Res (2007) 1.64
Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins. FEBS Lett (2009) 1.61
Nanotopographical modification: a regulator of cellular function through focal adhesions. Nanomedicine (2010) 1.55
Gene delivery through cell culture substrate adsorbed DNA complexes. Biotechnol Bioeng (2005) 1.50
The influence of microscale topography on fibroblast attachment and motility. Biomaterials (2004) 1.48
Matrices and scaffolds for DNA delivery in tissue engineering. Adv Drug Deliv Rev (2007) 1.47
Cytoskeleton: actin and endocytosis--no longer the weakest link. Curr Biol (2001) 1.31
Use of nanotopography to study mechanotransduction in fibroblasts--methods and perspectives. Eur J Cell Biol (2004) 1.30
Transfection microarray of human mesenchymal stem cells and on-chip siRNA gene knockdown. J Control Release (2004) 1.28
Gene expression and internalization following vector adsorption to immobilized proteins: dependence on protein identity and density. J Gene Med (2007) 1.23
Electrohydrodynamics: A facile technique to fabricate drug delivery systems. Adv Drug Deliv Rev (2009) 1.23
Neurotrophin releasing single and multiple lumen nerve conduits. J Control Release (2005) 1.17
Gene delivery by cationic lipids: in and out of an endosome. Biochem Soc Trans (2007) 1.15
Substrate-mediated delivery from self-assembled monolayers: effect of surface ionization, hydrophilicity, and patterning. Acta Biomater (2005) 1.14
Applications of transfected cell microarrays in high-throughput drug discovery. Drug Discov Today (2002) 1.09
Nanoscale cell adhesion ligand presentation regulates nonviral gene delivery and expression. Nano Lett (2007) 1.09
Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry. Biophys J (2008) 1.09
The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization. Biomaterials (2009) 1.05
Caveolae internalization regulates integrin-dependent signaling pathways. Cell Cycle (2006) 1.03
Identification of distinct topographical surface microstructures favoring either undifferentiated expansion or differentiation of murine embryonic stem cells. Stem Cells Dev (2009) 1.02
The response of fibroblasts to hexagonal nanotopography fabricated by electron beam lithography. J Biomed Mater Res A (2008) 1.02
Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios. Acta Biomater (2009) 1.00
Effect of nanoscale topography on fibronectin adsorption, focal adhesion size and matrix organisation. Colloids Surf B Biointerfaces (2010) 0.98
Differential uptake of DNA-poly(ethylenimine) polyplexes in cells cultured on collagen and fibronectin surfaces. Acta Biomater (2010) 0.90
Fibroblast signaling events in response to nanotopography: a gene array study. IEEE Trans Nanobioscience (2002) 0.90
The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response. Biomaterials (2006) 0.90
Surface polyethylene glycol enhances substrate-mediated gene delivery by nonspecifically immobilized complexes. Acta Biomater (2007) 0.90
Local call: from integrins to actin assembly. Trends Cell Biol (2006) 0.88
Fibronectin adsorption on tantalum: the influence of nanoroughness. J Phys Chem B (2008) 0.87
Tuning the mechanical properties of bioreducible multilayer films for improved cell adhesion and transfection activity. Biomaterials (2010) 0.86
A combinatorial screening of human fibroblast responses on micro-structured surfaces. Biomaterials (2010) 0.85
Method for reverse transfection using gold colloid as a nano-scaffold. J Biosci Bioeng (2007) 0.80
Nocodazole treatment of CV-1 cells enhances nuclear/perinuclear accumulation of lipid-DNA complexes and increases gene expression. Pharm Res (2001) 0.80
Highly efficient reverse transfection with siRNA in multiple wells of microtiter plates. J Biosci Bioeng (2007) 0.78
Reverse transfection using antibodies against a cell surface antigen in mammalian adherent cell lines. J Biosci Bioeng (2007) 0.77
RNA-guided gene activation by CRISPR-Cas9-based transcription factors. Nat Methods (2013) 4.85
Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials (2005) 2.94
Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res (2007) 2.46
Multifunctional nanorods for gene delivery. Nat Mater (2003) 2.09
Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells. Biomaterials (2009) 1.97
Development of universal antidotes to control aptamer activity. Nat Med (2009) 1.93
Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules (2005) 1.86
Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET. Mol Ther (2008) 1.76
The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials (2007) 1.72
Natural polymers for gene delivery and tissue engineering. Adv Drug Deliv Rev (2006) 1.66
Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression. ACS Nano (2011) 1.65
Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. J Control Release (2006) 1.64
Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success. J Mol Cell Cardiol (2013) 1.61
Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA. Angew Chem Int Ed Engl (2005) 1.61
Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. PLoS One (2013) 1.52
Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform. Adv Funct Mater (2007) 1.43
Significance of synthetic nanostructures in dictating cellular response. Nanomedicine (2005) 1.42
Mast cell-derived particles deliver peripheral signals to remote lymph nodes. J Exp Med (2009) 1.42
Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers. Biomaterials (2005) 1.42
Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells. Biomaterials (2006) 1.41
Chitosan nanoparticles for oral drug and gene delivery. Int J Nanomedicine (2006) 1.38
Characterization of topographical effects on macrophage behavior in a foreign body response model. Biomaterials (2010) 1.33
Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 1.31
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. Free Radic Biol Med (2011) 1.31
Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function. Biomaterials (2011) 1.30
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways. Antioxid Redox Signal (2013) 1.29
In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF). Biomaterials (2007) 1.28
Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for controlled drug delivery. Biomaterials (2006) 1.26
The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. Biomaterials (2004) 1.25
Biomaterials approach to expand and direct differentiation of stem cells. Mol Ther (2007) 1.24
Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma. Clin Cancer Res (2004) 1.23
Electrohydrodynamics: A facile technique to fabricate drug delivery systems. Adv Drug Deliv Rev (2009) 1.23
Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery. J R Soc Interface (2009) 1.22
Preparation and characterization of polypseudorotaxanes based on block-selected inclusion complexation between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin. J Am Chem Soc (2003) 1.20
Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells. Mol Ther Nucleic Acids (2012) 1.20
Myogenic Induction of Aligned Mesenchymal Stem Cell Sheets by Culture on Thermally Responsive Electrospun Nanofibers. Adv Mater (2007) 1.20
Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells. Biomaterials (2005) 1.19
Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers. J Biomed Mater Res A (2004) 1.19
MR imaging of biodegradable polymeric microparticles: a potential method of monitoring local drug delivery. Magn Reson Med (2005) 1.19
Nanotopography as modulator of human mesenchymal stem cell function. Biomaterials (2012) 1.16
Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery. Int J Nanomedicine (2006) 1.16
PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. Bioconjug Chem (2006) 1.15
Advanced materials and processing for drug delivery: the past and the future. Adv Drug Deliv Rev (2012) 1.14
Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes. J Control Release (2005) 1.13
Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nat Mater (2012) 1.12
Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture. Biomaterials (2006) 1.11
Microfluidic synthesis of multifunctional Janus particles for biomedical applications. Lab Chip (2012) 1.10
Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin. J Biomed Mater Res A (2006) 1.10
Viscoelastic behaviour of human mesenchymal stem cells. BMC Cell Biol (2008) 1.09
Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry. Biophys J (2008) 1.09
Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis. Spine (Phila Pa 1976) (2006) 1.09
Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency. Adv Mater (2010) 1.07
Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold. Biomaterials (2005) 1.07
Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment. Sci Rep (2013) 1.07
Engineering strategies to enhance nanoparticle-mediated oral delivery. J Biomater Sci Polym Ed (2008) 1.06
The use of combinatorial topographical libraries for the screening of enhanced osteogenic expression and mineralization. Biomaterials (2009) 1.05
Nucleic acid scavengers inhibit thrombosis without increasing bleeding. Proc Natl Acad Sci U S A (2012) 1.05
Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and alpha-cyclodextrin. J Biomed Mater Res A (2003) 1.05
Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers. Cell Mol Bioeng (2008) 1.04
Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. Biomaterials (2003) 1.04
Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection. Hum Gene Ther (2002) 1.04
Quantum dot-based theranostics. Nanoscale (2009) 1.03
Controlled release from fibers of polyelectrolyte complexes. J Control Release (2005) 1.02
Identification of distinct topographical surface microstructures favoring either undifferentiated expansion or differentiation of murine embryonic stem cells. Stem Cells Dev (2009) 1.02
Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format. J Control Release (2013) 1.02
Morphology, proliferation, and osteogenic differentiation of mesenchymal stem cells cultured on titanium, tantalum, and chromium surfaces. J Biomed Mater Res A (2008) 1.02
Guidance of stem cell fate on 2D patterned surfaces. Biomaterials (2012) 1.02
Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery. Nano Today (2010) 1.02
New polyphosphoramidate with a spermidine side chain as a gene carrier. J Control Release (2002) 1.01
Polyphosphoesters in drug and gene delivery. Adv Drug Deliv Rev (2003) 1.01
Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate. Free Radic Res (2011) 1.01
Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance. Acta Biomater (2005) 1.01
Co-culture of umbilical cord blood CD34+ cells with human mesenchymal stem cells. Tissue Eng (2006) 1.01
Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts. PLoS One (2010) 1.01
Tuning physical properties of nanocomplexes through microfluidics-assisted confinement. Nano Lett (2011) 1.00
Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. PLoS One (2013) 1.00
Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles. J Control Release (2008) 1.00
Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET. Nano Today (2009) 0.99
Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site. Free Radic Res (2010) 0.99
A programmable microenvironment for cellular studies via microfluidics-generated double emulsions. Biomaterials (2013) 0.99
Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression. J Biomater Sci Polym Ed (2004) 0.99
Sustained viral gene delivery through core-shell fibers. J Control Release (2009) 0.98
Nucleic acid-binding polymers as anti-inflammatory agents. Proc Natl Acad Sci U S A (2011) 0.98
Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold. J Biomater Sci Polym Ed (2005) 0.98
Low oxygen tension and synthetic nanogratings improve the uniformity and stemness of human mesenchymal stem cell layer. Mol Ther (2010) 0.97
Fibronectin adsorption, cell adhesion, and proliferation on nanostructured tantalum surfaces. ACS Nano (2010) 0.96
Design of polyphosphoester-DNA nanoparticles for non-viral gene delivery. Adv Genet (2005) 0.96
Mechanism of oral tolerance induction to therapeutic proteins. Adv Drug Deliv Rev (2012) 0.96
Efficient array-based identification of novel cardiac genes through differentiation of mouse ESCs. PLoS One (2008) 0.95
Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells. Exp Hematol (2007) 0.95
Deformation of stem cell nuclei by nanotopographical cues. Soft Matter (2010) 0.95
Poly(phosphoester) ionomers as tissue-engineering scaffolds. J Biomed Mater Res B Appl Biomater (2004) 0.94
Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions. J Gene Med (2006) 0.94
Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cells. Biomaterials (2006) 0.94
Detection of single enzymatic events in rare or single cells using microfluidics. ACS Nano (2011) 0.94