Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function.

PubWeight™: 1.30‹?› | Rank: Top 10%

🔗 View Article (PMC 3190071)

Published in Biomaterials on September 08, 2011

Authors

Brian Liau1, Nicolas Christoforou, Kam W Leong, Nenad Bursac

Author Affiliations

1: Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.

Articles citing this

Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes. Circ Res (2014) 2.34

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials (2013) 1.97

Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J (2013) 1.15

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo. Proc Natl Acad Sci U S A (2014) 1.10

Functional cardiac tissue engineering. Regen Med (2012) 1.07

Patching the heart: cardiac repair from within and outside. Circ Res (2013) 1.04

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther (2014) 1.03

Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. PLoS One (2013) 1.00

Controlling the structural and functional anisotropy of engineered cardiac tissues. Biofabrication (2014) 0.98

Functional consequences of a tissue-engineered myocardial patch for cardiac repair in a rat infarct model. Tissue Eng Part A (2014) 0.97

Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther (2014) 0.96

Three-dimensional filamentous human diseased cardiac tissue model. Biomaterials (2013) 0.91

Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies. Adv Drug Deliv Rev (2015) 0.91

Robust T-tubulation and maturation of cardiomyocytes using tissue-engineered epicardial mimetics. Biomaterials (2014) 0.91

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue. Circulation (2016) 0.90

Functional Effects of a Tissue-Engineered Cardiac Patch From Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Rat Infarct Model. Stem Cells Transl Med (2015) 0.87

Materials science and tissue engineering: repairing the heart. Mayo Clin Proc (2013) 0.87

Three-dimensional elastomeric scaffolds designed with cardiac-mimetic structural and mechanical features. Tissue Eng Part A (2012) 0.86

Electrical stimulation directs engineered cardiac tissue to an age-matched native phenotype. J Tissue Eng (2012) 0.86

Cardiac extracellular matrix-fibrin hybrid scaffolds with tunable properties for cardiovascular tissue engineering. Acta Biomater (2014) 0.85

Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells. Sci Rep (2015) 0.84

Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues. Adv Drug Deliv Rev (2015) 0.83

Genetic engineering of somatic cells to study and improve cardiac function. Europace (2012) 0.83

Use of flow, electrical, and mechanical stimulation to promote engineering of striated muscles. Ann Biomed Eng (2013) 0.83

Human pluripotent stem cell-derived cardiomyocytes as research and therapeutic tools. Biomed Res Int (2014) 0.83

Engineering myocardial tissue patches with hierarchical structure-function. Ann Biomed Eng (2014) 0.81

Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. Curr Opin Chem Eng (2015) 0.81

Dynamic culture yields engineered myocardium with near-adult functional output. Biomaterials (2016) 0.81

Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering. Biomark Insights (2015) 0.80

Strategies and Challenges to Myocardial Replacement Therapy. Stem Cells Transl Med (2016) 0.80

Human iPSC-derived cardiomyocytes and tissue engineering strategies for disease modeling and drug screening. Biotechnol Adv (2016) 0.79

Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening. Adv Drug Deliv Rev (2015) 0.79

In vitro cardiac tissue models: Current status and future prospects. Adv Drug Deliv Rev (2015) 0.78

Cardiac fibroblasts support endothelial cell proliferation and sprout formation but not the development of multicellular sprouts in a fibrin gel co-culture model. Ann Biomed Eng (2014) 0.78

Optimizing a spontaneously contracting heart tissue patch with rat neonatal cardiac cells on fibrin gel. J Tissue Eng Regen Med (2014) 0.78

Fibrous scaffolds for building hearts and heart parts. Adv Drug Deliv Rev (2015) 0.78

The role of tissue engineering and biomaterials in cardiac regenerative medicine. Can J Cardiol (2014) 0.78

Quantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs. Methods Mol Biol (2014) 0.78

Human Cardiomyocytes Prior to Birth by Integration-Free Reprogramming of Amniotic Fluid Cells. Stem Cells Transl Med (2016) 0.78

Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation. Stem Cell Res (2016) 0.77

Vascularization of three-dimensional engineered tissues for regenerative medicine applications. Acta Biomater (2016) 0.76

Striated muscle function, regeneration, and repair. Cell Mol Life Sci (2016) 0.76

Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs. Sci Rep (2016) 0.75

"The state of the heart": Recent advances in engineering human cardiac tissue from pluripotent stem cells. Exp Biol Med (Maywood) (2015) 0.75

Trends in cardiovascular engineering: organizing the human heart. Trends Cardiovasc Med (2013) 0.75

Regulation of the microenvironment for cardiac tissue engineering. Regen Med (2017) 0.75

Mechanotransduction and Metabolism in Cardiomyocyte Microdomains. Biomed Res Int (2016) 0.75

Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues. Sci Rep (2017) 0.75

Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models. Front Bioeng Biotechnol (2017) 0.75

Articles cited by this

Tissue engineering. Science (1993) 19.65

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol (2007) 14.48

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature (2008) 10.27

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart. Nat Med (2008) 10.15

Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation (1990) 9.74

Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell (2006) 7.21

Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med (2006) 4.74

Stem-cell-based therapy and lessons from the heart. Nature (2008) 4.54

Tissue engineering of a differentiated cardiac muscle construct. Circ Res (2002) 4.50

Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol (2004) 4.50

Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. J Biol Chem (1991) 4.34

Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell (2009) 4.21

Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc Natl Acad Sci U S A (2004) 4.13

Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater (2008) 4.00

Growth of engineered human myocardium with mechanical loading and vascular coculture. Circ Res (2011) 3.25

Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res (2007) 2.74

Generation of functional ventricular heart muscle from mouse ventricular progenitor cells. Science (2009) 2.60

Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc Natl Acad Sci U S A (2009) 2.51

Cardiogenesis and the complex biology of regenerative cardiovascular medicine. Science (2008) 2.30

Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development (1999) 2.24

Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium. J Exp Med (2006) 2.23

Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. Am J Physiol (1999) 2.19

Endothelial cells promote cardiac myocyte survival and spatial reorganization: implications for cardiac regeneration. Circulation (2004) 2.11

Non-linear elasticity of extracellular matrices enables contractile cells to communicate local position and orientation. PLoS One (2009) 2.06

Development of a drug screening platform based on engineered heart tissue. Circ Res (2010) 2.04

Pulsatile cardiac tissue grafts using a novel three-dimensional cell sheet manipulation technique functionally integrates with the host heart, in vivo. Circ Res (2006) 2.02

Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes. Biotechnol Bioeng (2000) 1.96

Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues. FASEB J (2006) 1.90

Fibrin gels and their clinical and bioengineering applications. J R Soc Interface (2009) 1.86

Null mutation of connexin43 causes slow propagation of ventricular activation in the late stages of mouse embryonic development. Circ Res (2001) 1.83

Stem cell therapy is proarrhythmic. Circulation (2009) 1.83

Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. J Clin Invest (2008) 1.80

Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes. J Physiol (2004) 1.71

The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle. Biomaterials (2011) 1.68

In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes. Stem Cells Dev (2010) 1.65

Cardiac cell-cell junctions in health and disease: Electrical versus mechanical coupling. J Mol Cell Cardiol (2009) 1.58

Selection of ventricular-like cardiomyocytes from ES cells in vitro. FASEB J (2000) 1.56

Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues. Nat Protoc (2009) 1.45

Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation. Stem Cells Dev (2010) 1.44

Cell-induced alignment augments twitch force in fibrin gel-based engineered myocardium via gap junction modification. Tissue Eng Part A (2009) 1.44

Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes. Cardiovasc Res (2009) 1.40

I(f) current and spontaneous activity in mouse embryonic ventricular myocytes. Circ Res (2001) 1.40

Novel micropatterned cardiac cell cultures with realistic ventricular microstructure. Biophys J (2009) 1.30

Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts. Circ Res (2003) 1.29

Novel anisotropic engineered cardiac tissues: studies of electrical propagation. Biochem Biophys Res Commun (2007) 1.29

Creation of engineered cardiac tissue in vitro from mouse embryonic stem cells. Circulation (2006) 1.27

Self-organization of rat cardiac cells into contractile 3-D cardiac tissue. FASEB J (2004) 1.22

Lentiviral vector-mediated expression of GFP or Kir2.1 alters the electrophysiology of neonatal rat ventricular myocytes without inducing cytotoxicity. Am J Physiol Heart Circ Physiol (2007) 1.18

Engineered early embryonic cardiac tissue retains proliferative and contractile properties of developing embryonic myocardium. Am J Physiol Heart Circ Physiol (2006) 1.14

Multiarm spirals in a two-dimensional cardiac substrate. Proc Natl Acad Sci U S A (2004) 1.13

Contractile three-dimensional bioengineered heart muscle for myocardial regeneration. J Biomed Mater Res A (2007) 1.12

Interrogating functional integration between injected pluripotent stem cell-derived cells and surrogate cardiac tissue. Proc Natl Acad Sci U S A (2009) 1.10

Pacemaker synchronization of electrically coupled rabbit sinoatrial node cells. J Gen Physiol (1998) 1.06

Stiffening of individual fibrin fibers equitably distributes strain and strengthens networks. Biophys J (2010) 1.05

Mechanical properties of the heart muscle in the passive state. J Biomech (1973) 1.02

Insulin-like growth factor-I and slow, bi-directional perfusion enhance the formation of tissue-engineered cardiac grafts. Tissue Eng Part A (2009) 1.02

Neonatal mouse-derived engineered cardiac tissue: a novel model system for studying genetic heart disease. Circ Res (2011) 1.02

Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapy. Circ Res (2007) 1.02

A novel miniaturized multimodal bioreactor for continuous in situ assessment of bioartificial cardiac tissue during stimulation and maturation. Tissue Eng Part C Methods (2011) 0.99

Lack of laminin gamma1 in embryonic stem cell-derived cardiomyocytes causes inhomogeneous electrical spreading despite intact differentiation and function. Stem Cells (2009) 0.93

Fibroblasts facilitate the engraftment of embryonic stem cell-derived cardiomyocytes on three-dimensional collagen matrices and aggregation in hanging drops. Stem Cells Dev (2010) 0.85

Determination of electrical properties of ES cell-derived cardiomyocytes using MEAs. J Electrocardiol (2004) 0.84

Fibroblasts support functional integration of purified embryonic stem cell-derived cardiomyocytes into avital myocardial tissue. Stem Cells Dev (2011) 0.83

Impulse propagation in late-stage embryonic and neonatal murine ventricular slices. J Electrocardiol (2006) 0.81

Articles by these authors

RNA-guided gene activation by CRISPR-Cas9-based transcription factors. Nat Methods (2013) 4.85

Nanopattern-induced changes in morphology and motility of smooth muscle cells. Biomaterials (2005) 2.94

Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res (2007) 2.46

Multifunctional nanorods for gene delivery. Nat Mater (2003) 2.09

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials (2013) 1.97

Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells. Biomaterials (2009) 1.97

Development of universal antidotes to control aptamer activity. Nat Med (2009) 1.93

Sustained release of proteins from electrospun biodegradable fibers. Biomacromolecules (2005) 1.86

Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET. Mol Ther (2008) 1.76

The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials (2007) 1.72

The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle. Biomaterials (2011) 1.68

Natural polymers for gene delivery and tissue engineering. Adv Drug Deliv Rev (2006) 1.66

Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression. ACS Nano (2011) 1.65

Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. J Control Release (2006) 1.64

Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success. J Mol Cell Cardiol (2013) 1.61

Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA. Angew Chem Int Ed Engl (2005) 1.61

Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. PLoS One (2013) 1.52

Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues. Nat Protoc (2009) 1.45

Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform. Adv Funct Mater (2007) 1.43

Significance of synthetic nanostructures in dictating cellular response. Nanomedicine (2005) 1.42

Mast cell-derived particles deliver peripheral signals to remote lymph nodes. J Exp Med (2009) 1.42

Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers. Biomaterials (2005) 1.42

Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells. Biomaterials (2006) 1.41

Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes. Cardiovasc Res (2009) 1.40

Chitosan nanoparticles for oral drug and gene delivery. Int J Nanomedicine (2006) 1.38

Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts. Circ Res (2011) 1.37

Characterization of topographical effects on macrophage behavior in a foreign body response model. Biomaterials (2010) 1.33

Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 1.31

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. Free Radic Biol Med (2011) 1.31

Novel micropatterned cardiac cell cultures with realistic ventricular microstructure. Biophys J (2009) 1.30

SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways. Antioxid Redox Signal (2013) 1.29

Engineered skeletal muscle tissue networks with controllable architecture. Biomaterials (2008) 1.28

Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay. Am J Physiol Heart Circ Physiol (2008) 1.28

In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF). Biomaterials (2007) 1.28

Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for controlled drug delivery. Biomaterials (2006) 1.26

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. Biomaterials (2004) 1.25

Biomaterials approach to expand and direct differentiation of stem cells. Mol Ther (2007) 1.24

Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma. Clin Cancer Res (2004) 1.23

Electrohydrodynamics: A facile technique to fabricate drug delivery systems. Adv Drug Deliv Rev (2009) 1.23

Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery. J R Soc Interface (2009) 1.22

Functional reentry in cultured monolayers of neonatal rat cardiac cells. Am J Physiol Heart Circ Physiol (2003) 1.22

Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells. Mol Ther Nucleic Acids (2012) 1.20

Myogenic Induction of Aligned Mesenchymal Stem Cell Sheets by Culture on Thermally Responsive Electrospun Nanofibers. Adv Mater (2007) 1.20

Preparation and characterization of polypseudorotaxanes based on block-selected inclusion complexation between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin. J Am Chem Soc (2003) 1.20

Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells. Biomaterials (2005) 1.19

Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers. J Biomed Mater Res A (2004) 1.19

MR imaging of biodegradable polymeric microparticles: a potential method of monitoring local drug delivery. Magn Reson Med (2005) 1.19

Nanotopography as modulator of human mesenchymal stem cell function. Biomaterials (2012) 1.16

Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery. Int J Nanomedicine (2006) 1.16

PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. Bioconjug Chem (2006) 1.15

Advanced materials and processing for drug delivery: the past and the future. Adv Drug Deliv Rev (2012) 1.14

Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes. J Control Release (2005) 1.13

Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. Nat Mater (2012) 1.12

Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture. Biomaterials (2006) 1.11

Microfluidic synthesis of multifunctional Janus particles for biomedical applications. Lab Chip (2012) 1.10

Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin. J Biomed Mater Res A (2006) 1.10

Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies. Nat Commun (2011) 1.10

Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo. Proc Natl Acad Sci U S A (2014) 1.10

Electrotonic loading of anisotropic cardiac monolayers by unexcitable cells depends on connexin type and expression level. Am J Physiol Cell Physiol (2009) 1.09

Viscoelastic behaviour of human mesenchymal stem cells. BMC Cell Biol (2008) 1.09

Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis. Spine (Phila Pa 1976) (2006) 1.09

Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry. Biophys J (2008) 1.09

Whole-cell-analysis of live cardiomyocytes using wide-field interferometric phase microscopy. Biomed Opt Express (2010) 1.08

Electrical pacing counteracts intrinsic shortening of action potential duration of neonatal rat ventricular cells in culture. J Mol Cell Cardiol (2006) 1.08

Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency. Adv Mater (2010) 1.07

Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold. Biomaterials (2005) 1.07

Functional cardiac tissue engineering. Regen Med (2012) 1.07

Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment. Sci Rep (2013) 1.07

Engineering strategies to enhance nanoparticle-mediated oral delivery. J Biomater Sci Polym Ed (2008) 1.06

Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and alpha-cyclodextrin. J Biomed Mater Res A (2003) 1.05

Nucleic acid scavengers inhibit thrombosis without increasing bleeding. Proc Natl Acad Sci U S A (2012) 1.05

Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers. Cell Mol Bioeng (2008) 1.04

Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. Biomaterials (2003) 1.04

Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection. Hum Gene Ther (2002) 1.04

Quantum dot-based theranostics. Nanoscale (2009) 1.03

Local tissue geometry determines contractile force generation of engineered muscle networks. Tissue Eng Part A (2012) 1.03

Controlled release from fibers of polyelectrolyte complexes. J Control Release (2005) 1.02

Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format. J Control Release (2013) 1.02

Guidance of stem cell fate on 2D patterned surfaces. Biomaterials (2012) 1.02

Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery. Nano Today (2010) 1.02

New polyphosphoramidate with a spermidine side chain as a gene carrier. J Control Release (2002) 1.01

Polyphosphoesters in drug and gene delivery. Adv Drug Deliv Rev (2003) 1.01

Co-culture of umbilical cord blood CD34+ cells with human mesenchymal stem cells. Tissue Eng (2006) 1.01

Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance. Acta Biomater (2005) 1.01

Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate. Free Radic Res (2011) 1.01

Cardiac cell therapy in vitro: reproducible assays for comparing the efficacy of different donor cells. IEEE Eng Med Biol Mag (2008) 1.01

Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts. PLoS One (2010) 1.01

Tuning physical properties of nanocomplexes through microfluidics-assisted confinement. Nano Lett (2011) 1.00

Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. PLoS One (2013) 1.00

Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles. J Control Release (2008) 1.00

Mechanoelectrical excitation by fluid jets in monolayers of cultured cardiac myocytes. J Appl Physiol (1985) (2005) 1.00

Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site. Free Radic Res (2010) 0.99

A programmable microenvironment for cellular studies via microfluidics-generated double emulsions. Biomaterials (2013) 0.99

Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET. Nano Today (2009) 0.99

Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression. J Biomater Sci Polym Ed (2004) 0.99