Published in BMC Med Res Methodol on February 21, 2011
A tutorial on sensitivity analyses in clinical trials: the what, why, when and how. BMC Med Res Methodol (2013) 1.63
Random-effects, fixed-effects and the within-between specification for clustered data in observational health studies: a simulation study. PLoS One (2014) 1.58
The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies. Trials (2014) 1.54
Surrounding greenness and pregnancy outcomes in four Spanish birth cohorts. Environ Health Perspect (2012) 1.25
Accounting for centre-effects in multicentre trials with a binary outcome - when, why, and how? BMC Med Res Methodol (2014) 1.12
Clustering in surgical trials--database of intracluster correlations. Trials (2012) 1.06
Imaging biomarker roadmap for cancer studies. Nat Rev Clin Oncol (2016) 0.99
Adjusting for multiple prognostic factors in the analysis of randomised trials. BMC Med Res Methodol (2013) 0.99
Update on the transfusion in gastrointestinal bleeding (TRIGGER) trial: statistical analysis plan for a cluster-randomised feasibility trial. Trials (2013) 0.93
Many multicenter trials had few events per center, requiring analysis via random-effects models or GEEs. J Clin Epidemiol (2015) 0.91
Recommendations for the Design and Analysis of Treatment Trials for Alcohol Use Disorders. Alcohol Clin Exp Res (2015) 0.80
Analyzing Clustered Data: Why and How to Account for Multiple Observations Nested within a Study Participant? PLoS One (2016) 0.79
Use of clustering analysis in randomized controlled trials in orthopaedic surgery. BMC Med Res Methodol (2015) 0.75
Reanalysis of morphine consumption from two randomized controlled trials of gabapentin using longitudinal statistical methods. J Pain Res (2015) 0.75
Gait Change Is Associated with Cognitive Outcome after an Acute Ischemic Stroke. Front Aging Neurosci (2017) 0.75
Meta-analysis in clinical trials. Control Clin Trials (1986) 144.91
ICH Harmonised Tripartite Guideline. Statistical principles for clinical trials. International Conference on Harmonisation E9 Expert Working Group. Stat Med (1999) 7.32
Design and analysis of group-randomized trials: a review of recent methodological developments. Am J Public Health (2004) 5.89
Patterns of intra-cluster correlation from primary care research to inform study design and analysis. J Clin Epidemiol (2004) 5.44
Adjustments for center in multicenter studies: an overview. Ann Intern Med (2001) 5.28
The intracluster correlation coefficient in cluster randomisation. BMJ (1998) 4.07
Bayesian approaches to random-effects meta-analysis: a comparative study. Stat Med (1995) 3.71
A covariance estimator for GEE with improved small-sample properties. Biometrics (2001) 3.65
Modelling clustered survival data from multicentre clinical trials. Stat Med (2004) 3.02
Individualized electronic decision support and reminders to improve diabetes care in the community: COMPETE II randomized trial. CMAJ (2009) 2.58
Intraclass correlation coefficients for cluster randomized trials in primary care: data from the MRC Trial of the Assessment and Management of Older People in the Community. Control Clin Trials (2002) 2.36
Analysis of data from multiclinic trials. Control Clin Trials (1986) 2.01
Some controversies in planning and analysing multi-centre trials. Stat Med (1998) 1.86
A general maximum likelihood analysis of variance components in generalized linear models. Biometrics (1999) 1.70
Intraclass correlation coefficients for cluster randomized trials in primary care: the cholesterol education and research trial (CEART). Contemp Clin Trials (2005) 1.69
A comparison between traditional methods and multilevel regression for the analysis of multicenter intervention studies. J Clin Epidemiol (2003) 1.58
Using empirical Bayes methods in biopharmaceutical research. Stat Med (1991) 1.33
Strategies for comparing treatments on a binary response with multi-centre data. Stat Med (2000) 1.26
A Bayesian approach to jointly estimate centre and treatment by centre heterogeneity in a proportional hazards model. Stat Med (2005) 1.09
A simulation study of odds ratio estimation for binary outcomes from cluster randomized trials. Stat Med (2007) 1.03
A comparison of various estimators of a treatment difference for a multi-centre clinical trial. Stat Med (1998) 1.02
An issue of statistical analysis in controlled multi-centre studies: how shall we weight the centres? Stat Med (1999) 0.99
Multi-centre trial analysis revisited. Stat Med (1998) 0.95
The design of multicentre trials. Stat Methods Med Res (2005) 0.93
The analysis of continuous outcomes in multi-centre trials with small centre sizes. Stat Med (2007) 0.91
Relative efficiency of unequal cluster sizes for variance component estimation in cluster randomized and multicentre trials. Stat Methods Med Res (2007) 0.85
Regression analysis with clustered data. Stat Med (1994) 0.84
Methods for pooling results from multi-center studies. J Dent Res (2004) 0.83
Analysis of data from multiclinic trials. Control Clin Trials (1987) 0.83
The application of REML in clinical trials. Stat Med (1994) 0.82
Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial. Lancet (2010) 12.92
Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. JAMA (2006) 11.71
Randomized trial of primary PCI with or without routine manual thrombectomy. N Engl J Med (2015) 7.83
A tutorial on pilot studies: the what, why and how. BMC Med Res Methodol (2010) 7.47
Prednisolone and Mycobacterium indicus pranii in tuberculous pericarditis. N Engl J Med (2014) 6.65
Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension. Anesthesiology (2013) 5.69
Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA (2012) 4.58
Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96
Improving cardiovascular health at population level: 39 community cluster randomised trial of Cardiovascular Health Awareness Program (CHAP). BMJ (2011) 3.81
Femoral nerve block improves analgesia outcomes after total knee arthroplasty: a meta-analysis of randomized controlled trials. Anesthesiology (2010) 3.42
The safety of long-acting beta-agonists among patients with asthma using inhaled corticosteroids: systematic review and metaanalysis. Am J Respir Crit Care Med (2008) 3.01
Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer. J Clin Endocrinol Metab (2004) 2.86
Second primary malignancy risk after radioactive iodine treatment for thyroid cancer: a systematic review and meta-analysis. Thyroid (2009) 2.79
Acute rehabilitation practices in critically ill children: a multicenter study. Pediatr Crit Care Med (2014) 2.71
Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study. CMAJ (2009) 2.64
Bayesian meta-analysis of hormone therapy and mortality in younger postmenopausal women. Am J Med (2009) 2.64
Individualized electronic decision support and reminders to improve diabetes care in the community: COMPETE II randomized trial. CMAJ (2009) 2.58
Application of data mining techniques in pharmacovigilance. Br J Clin Pharmacol (2004) 2.32
Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses? Int J Epidemiol (2008) 2.31
Quality of reporting of randomized controlled trials in general endocrinology literature. J Clin Endocrinol Metab (2008) 2.24
The efficacy of botulinum toxin type A in managing chronic musculoskeletal pain: a systematic review and meta analysis. Inflammopharmacology (2010) 2.11
The Cameroon Mobile Phone SMS (CAMPS) trial: a randomized trial of text messaging versus usual care for adherence to antiretroviral therapy. PLoS One (2012) 2.05
Meta-analysis: cardiovascular events associated with nonsteroidal anti-inflammatory drugs. Am J Med (2006) 2.02
The number of patients and events required to limit the risk of overestimation of intervention effects in meta-analysis--a simulation study. PLoS One (2011) 2.02
Alternatives to project-specific consent for access to personal information for health research: what is the opinion of the Canadian public? J Am Med Inform Assoc (2007) 1.98
A systematic review and meta-analysis of studies using the STRATIFY tool for prediction of falls in hospital patients: how well does it work? Age Ageing (2008) 1.94
The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol. Trials (2009) 1.92
Measuring patient preferences for colorectal cancer screening using a choice-format survey. Value Health (2007) 1.86
Views on health information sharing and privacy from primary care practices using electronic medical records. Int J Med Inform (2010) 1.83
Hypotonic versus isotonic maintenance fluids after surgery for children: a randomized controlled trial. Pediatrics (2011) 1.82
Male involvement in prevention programs of mother to child transmission of HIV: a systematic review to identify barriers and facilitators. Syst Rev (2013) 1.82
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial. Can J Anaesth (2013) 1.80
The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis. Diabetes Care (2010) 1.67
Mobile phone text messages for improving adherence to antiretroviral therapy (ART): an individual patient data meta-analysis of randomised trials. BMJ Open (2013) 1.66
Exercise for improving outcomes after osteoporotic vertebral fracture. Cochrane Database Syst Rev (2013) 1.63
Association between framing of the research question using the PICOT format and reporting quality of randomized controlled trials. BMC Med Res Methodol (2010) 1.63
Pregnancy outcomes in women with chronic kidney disease: a systematic review. Clin J Am Soc Nephrol (2011) 1.59
Sex differences in hospital admissions from emergency departments in asthmatic adults: a population-based study. Ann Allergy Asthma Immunol (2006) 1.57
Features predicting the success of computerized decision support for prescribing: a systematic review of randomized controlled trials. BMC Med Inform Decis Mak (2009) 1.55
Assessment of the quality and variability of health information on chronic pain websites using the DISCERN instrument. BMC Med (2010) 1.55
"Sleepiness" is serious in adolescence: two surveys of 3235 Canadian students. BMC Public Health (2006) 1.53
Multicenter evaluation of the use of venous thromboembolism prophylaxis in acutely ill medical patients in Canada. Thromb Res (2006) 1.48
Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology (2014) 1.47
Potentiating cancer immunotherapy using an oncolytic virus. Mol Ther (2010) 1.46
Preferences for evidence-based practice dissemination in addiction agencies serving women: a discrete-choice conjoint experiment. Addiction (2012) 1.45
Despite 2009 guidelines, few women report being counseled correctly about weight gain during pregnancy. Am J Obstet Gynecol (2011) 1.45
An updated systematic review and commentary examining the effectiveness of radioactive iodine remnant ablation in well-differentiated thyroid cancer. Endocrinol Metab Clin North Am (2008) 1.44
Sample sizes for clinical trials using sputum eosinophils as a primary outcome. Eur Respir J (2013) 1.42
Quality of randomized controlled trials reporting in the primary treatment of brain tumors. J Clin Oncol (2006) 1.42
The correlation between esophageal and abdominal pressures in mechanically ventilated patients undergoing laparoscopic surgery. Respir Care (2013) 1.39
Prophylactic antibiotic regimens in tumour surgery (PARITY): protocol for a multicentre randomised controlled study. BMJ Open (2012) 1.38
Attitudes of women who are currently using or recently stopped estrogen replacement therapy with or without progestins: results of the AWARE survey. J Obstet Gynaecol Can (2004) 1.38
Metastatic renal cell cancer treatments: an indirect comparison meta-analysis. BMC Cancer (2009) 1.37
Consent for use of personal information for health research: do people with potentially stigmatizing health conditions and the general public differ in their opinions? BMC Med Ethics (2009) 1.36
Emergency Department and Walk-in Clinic Use in Models of Primary Care Practice with Different After-Hours Accessibility in Ontario. Healthc Policy (2008) 1.36
Adverse events associated with pyrazinamide and levofloxacin in the treatment of latent multidrug-resistant tuberculosis. CMAJ (2002) 1.34
Patients' consent preferences regarding the use of their health information for research purposes: a qualitative study. J Health Serv Res Policy (2004) 1.34
Alternatives to project-specific consent for access to personal information for health research: insights from a public dialogue. BMC Med Ethics (2008) 1.33
Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses. PLoS One (2012) 1.33
Do hip protectors decrease the risk of hip fracture in institutional and community-dwelling elderly? A systematic review and meta-analysis of randomized controlled trials. Osteoporos Int (2005) 1.31
Systematic review of influenza resistance to the neuraminidase inhibitors. BMC Infect Dis (2011) 1.31
In-depth analysis of patient-clinician cell phone communication during the WelTel Kenya1 antiretroviral adherence trial. PLoS One (2012) 1.30
Does alendronate reduce the risk of fracture in men? A meta-analysis incorporating prior knowledge of anti-fracture efficacy in women. BMC Musculoskelet Disord (2005) 1.27
Computerized clinical decision support systems for drug prescribing and management: a decision-maker-researcher partnership systematic review. Implement Sci (2011) 1.26
Is plasma vitamin C an appropriate biomarker of vitamin C intake? A systematic review and meta-analysis. Nutr J (2007) 1.21
Predictors of unanticipated admission following ambulatory surgery: a retrospective case-control study. Can J Anaesth (2013) 1.21
Do patients perceive a link between a fragility fracture and osteoporosis? BMC Musculoskelet Disord (2008) 1.16
A review of studies examining stated preferences for cancer screening. Prev Chronic Dis (2006) 1.14
The impact of thyroid cancer and post-surgical radioactive iodine treatment on the lives of thyroid cancer survivors: a qualitative study. PLoS One (2009) 1.11
Hip protectors decrease hip fracture risk in elderly nursing home residents: a Bayesian meta-analysis. J Clin Epidemiol (2006) 1.09
Considerations in using text messages to improve adherence to highly active antiretroviral therapy: a qualitative study among clients in Yaoundé, Cameroon. HIV AIDS (Auckl) (2012) 1.08
A systematic scoping review of adherence to reporting guidelines in health care literature. J Multidiscip Healthc (2013) 1.07
Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study. AIDS Res Ther (2010) 1.06
Modelling heterogeneity variances in multiple treatment comparison meta-analysis--are informative priors the better solution? BMC Med Res Methodol (2013) 1.06
How to set-up a long-distance mentoring program: a framework and case description of mentorship in HIV clinical trials. J Multidiscip Healthc (2013) 1.05
Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study. PLoS One (2013) 1.04
Cardiovascular Health Awareness Program (CHAP): a community cluster-randomised trial among elderly Canadians. Prev Med (2008) 1.04
Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure. Compr Psychiatry (2008) 1.04
Genetic polymorphisms of glutathione S-transferases and the risk of adult brain tumors: a meta-analysis. Cancer Epidemiol Biomarkers Prev (2005) 1.03
Second primary malignancy risk in thyroid cancer survivors: a systematic review and meta-analysis. Thyroid (2007) 1.03
A systematic review of medication safety outcomes related to drug interaction software. J Popul Ther Clin Pharmacol (2010) 1.02
Tips for charting the course of a successful health research career. J Multidiscip Healthc (2013) 1.02
Sex differences in outcomes of methadone maintenance treatment for opioid addiction: a systematic review protocol. Syst Rev (2014) 1.01
Methodologic issues in health informatics trials: the complexities of complex interventions. J Am Med Inform Assoc (2008) 1.01
Which Surgical Treatment for Open Tibial Shaft Fractures Results in the Fewest Reoperations? A Network Meta-analysis. Clin Orthop Relat Res (2015) 1.01
Clinical predictors of developmental outcome in patients with cephaloceles. J Neurosurg Pediatr (2008) 1.00
The economic implications of three biochemical screening algorithms for pheochromocytoma. J Clin Endocrinol Metab (2004) 1.00
Fracture risk associated with continuation versus discontinuation of bisphosphonates after 5 years of therapy in patients with primary osteoporosis: a systematic review and meta-analysis. Ther Clin Risk Manag (2011) 1.00
Network Meta-analysis: Users' Guide for Surgeons: Part II - Certainty. Clin Orthop Relat Res (2015) 1.00
The relative efficacy of nine osteoporosis medications for reducing the rate of fractures in post-menopausal women. BMC Musculoskelet Disord (2011) 0.99
Comparison of Bayesian and classical methods in the analysis of cluster randomized controlled trials with a binary outcome: the Community Hypertension Assessment Trial (CHAT). BMC Med Res Methodol (2009) 0.98