Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis.

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🔗 View Article (PMID 20197533)

Published in JAMA on March 03, 2010

Authors

Matthias Briel1, Maureen Meade, Alain Mercat, Roy G Brower, Daniel Talmor, Stephen D Walter, Arthur S Slutsky, Eleanor Pullenayegum, Qi Zhou, Deborah Cook, Laurent Brochard, Jean-Christophe M Richard, Francois Lamontagne, Neera Bhatnagar, Thomas E Stewart, Gordon Guyatt

Author Affiliations

1: Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.

Associated clinical trials:

EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures (EPVent2) | NCT01681225

Local Assessment of Ventilatory Management During General Anesthesia for Surgery (LAS VEGAS) | NCT01601223

Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation (M'RHICO) | NCT02574169

Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO | NCT02027129

Clinical and Biological Markers in Acute Respiratory Failure | NCT02019095

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) | NCT01478802

Clinical Evaluation of Ventilador Innovation Product in Colombia in the SARS COVID 19 Pandemic, Unisabana Herons. (SabanaHerons) | NCT04497623

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