Published in Summit on Translat Bioinforma on March 01, 2009
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52
Lethality and centrality in protein networks. Nature (2001) 29.64
The human disease network. Proc Natl Acad Sci U S A (2007) 19.58
EnsMart: a generic system for fast and flexible access to biological data. Genome Res (2004) 17.64
Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science (2001) 17.11
A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol (2007) 9.90
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res (2002) 9.50
Modular organization of cellular networks. Proc Natl Acad Sci U S A (2003) 6.24
The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. PLoS Comput Biol (2007) 5.63
The HUGO Gene Nomenclature Database, 2006 updates. Nucleic Acids Res (2006) 5.02
Discovering disease-genes by topological features in human protein-protein interaction network. Bioinformatics (2006) 3.55
Network properties of genes harboring inherited disease mutations. Proc Natl Acad Sci U S A (2008) 3.37
Why do hubs tend to be essential in protein networks? PLoS Genet (2006) 3.29
Michigan Molecular Interactions (MiMI): putting the jigsaw puzzle together. Nucleic Acids Res (2006) 2.77
Molecular triangulation: bridging linkage and molecular-network information for identifying candidate genes in Alzheimer's disease. Proc Natl Acad Sci U S A (2004) 1.94
Global network analysis of phenotypic effects: protein networks and toxicity modulation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.90
PhenoGO: assigning phenotypic context to gene ontology annotations with natural language processing. Pac Symp Biocomput (2006) 1.76
Relationship between gene expression and GC-content in mammals: statistical significance and biological relevance. Hum Mol Genet (2004) 1.33
Discovery of protein interaction networks shared by diseases. Pac Symp Biocomput (2007) 1.30
Characterizing disease states from topological properties of transcriptional regulatory networks. BMC Bioinformatics (2006) 1.27
A network of transcriptionally coordinated functional modules in Saccharomyces cerevisiae. Genome Res (2005) 1.04
Interacting gene clusters and the evolution of the vertebrate immune system. Mol Biol Evol (2008) 0.89
Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Res (2002) 3.62
Joint estimation of multiple graphical models. Biometrika (2011) 3.08
Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype. J Proteome Res (2006) 2.43
Analysis of gene sets based on the underlying regulatory network. J Comput Biol (2009) 1.67
Penalized likelihood methods for estimation of sparse high-dimensional directed acyclic graphs. Biometrika (2010) 1.45
Network enrichment analysis in complex experiments. Stat Appl Genet Mol Biol (2010) 1.44
Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: systematic variation between sample types and calibration of mass spectrometry data. Proteomics (2005) 1.38
Discovering graphical Granger causality using the truncating lasso penalty. Bioinformatics (2010) 1.31
Temporal quantitative proteomics by iTRAQ 2D-LC-MS/MS and corresponding mRNA expression analysis identify post-transcriptional modulation of actin-cytoskeleton regulators during TGF-beta-Induced epithelial-mesenchymal transition. J Proteome Res (2009) 1.29
Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression. Cancer Res (2011) 1.26
Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells. PLoS One (2011) 1.25
Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens. J Proteome Res (2004) 1.19
Comparing exposure metrics for classifying 'dangerous heat' in heat wave and health warning systems. Environ Int (2012) 1.19
The role of sarcosine metabolism in prostate cancer progression. Neoplasia (2013) 1.18
Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer. Mol Cell Proteomics (2009) 1.13
Coupled global and targeted proteomics of human embryonic stem cells during induced differentiation. Mol Cell Proteomics (2008) 1.11
Quantitative organellar proteomics analysis of rough endoplasmic reticulum from normal and acute pancreatitis rat pancreas. J Proteome Res (2010) 1.11
Early events of Bacillus anthracis germination identified by time-course quantitative proteomics. Proteomics (2006) 1.10
Structural and functional discovery in dynamic networks with non-negative matrix factorization. Phys Rev E Stat Nonlin Soft Matter Phys (2013) 1.07
Pairwise variable selection for high-dimensional model-based clustering. Biometrics (2010) 0.96
Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels. Proc Natl Acad Sci U S A (2009) 0.95
Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer. J Proteome Res (2013) 0.92
Food deprivation-induced expression of minoxidil sulfotransferase in the hypothalamus uncovered by microarray analysis. J Biol Chem (2002) 0.87
OKVAR-Boost: a novel boosting algorithm to infer nonlinear dynamics and interactions in gene regulatory networks. Bioinformatics (2013) 0.85
Transcriptional and metabolic data integration and modeling for identification of active pathways. Biostatistics (2012) 0.83
THINK Back: KNowledge-based Interpretation of High Throughput data. BMC Bioinformatics (2012) 0.80
A graph algebra for scalable visual analytics. IEEE Comput Graph Appl (2014) 0.75
Determination of chorionicity by three-dimensional ultrasonography in a quadruplet pregnancy. Acta Obstet Gynecol Scand (2004) 0.75
The ensemble bridge algorithm: a new modeling tool for drug discovery problems. J Chem Inf Model (2010) 0.75
Graph-based semisupervised learning. IEEE Trans Pattern Anal Mach Intell (2008) 0.75