Published in Genome Med on January 22, 2011
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Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol (2009) 25.96
Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med (2007) 10.02
Oscillations in NF-kappaB signaling control the dynamics of gene expression. Science (2004) 8.44
Immune and inflammatory mechanisms of atherosclerosis (*). Annu Rev Immunol (2009) 5.28
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Mol Syst Biol (2008) 4.61
Phagocyte partnership during the onset and resolution of inflammation. Nat Rev Immunol (2010) 4.07
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity (2010) 3.88
Toward a detailed computational model for the mammalian circadian clock. Proc Natl Acad Sci U S A (2003) 3.69
Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease. Kidney Int (2007) 3.09
Gene expression dynamics in the macrophage exhibit criticality. Proc Natl Acad Sci U S A (2008) 1.95
In vitro-derived alternatively activated macrophages reduce colonic inflammation in mice. Gastroenterology (2010) 1.61
A logic-based diagram of signalling pathways central to macrophage activation. BMC Syst Biol (2008) 1.49
Modeling the immune rheostat of macrophages in the lung in response to infection. Proc Natl Acad Sci U S A (2009) 1.38
FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions. Genome Biol (2009) 1.32
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis. Biophys J (2009) 1.12
Mathematical modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumour sites. J Theor Biol (2004) 1.09
A genome-wide analysis of LPS tolerance in macrophages. Immunobiology (2007) 1.05
Logic models of pathway biology. Drug Discov Today (2008) 1.04
Bone-marrow-derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis. Mol Ther (2002) 1.01
Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications. Clin Sci (Lond) (2010) 1.00
Model of colonic inflammation: immune modulatory mechanisms in inflammatory bowel disease. J Theor Biol (2010) 0.99
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems. BMC Syst Biol (2010) 0.98
Macrophages transfected with adenovirus to express IL-4 reduce inflammation in experimental glomerulonephritis. J Immunol (2001) 0.96
Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling. BMC Genomics (2009) 0.92
Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease? Philos Trans A Math Phys Eng Sci (2006) 0.85
Use of logic theory in understanding regulatory pathway signaling in response to infection. Future Microbiol (2010) 0.79
Network dynamics. Methods Mol Biol (2009) 0.77
The Systems Biology Graphical Notation. Nat Biotechnol (2009) 8.53
The International HIV Dementia Scale: a new rapid screening test for HIV dementia. AIDS (2005) 4.48
Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance. AIDS (2009) 2.88
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity (2012) 1.96
Macrophage/monocyte depletion by clodronate, but not diphtheria toxin, improves renal ischemia/reperfusion injury in mice. Kidney Int (2012) 1.92
Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort. AIDS (2011) 1.90
Depression symptoms and cognitive function among individuals with advanced HIV infection initiating HAART in Uganda. BMC Psychiatry (2010) 1.73
Infusion of IL-10-expressing cells protects against renal ischemia through induction of lipocalin-2. Kidney Int (2012) 1.69
Increased human immunodeficiency virus type 1 (HIV-1) env compartmentalization in the presence of HIV-1-associated dementia. J Virol (2005) 1.65
HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda. Clin Infect Dis (2009) 1.64
Clinical validation of the NeuroScreen. J Neurovirol (2005) 1.57
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. PLoS Biol (2011) 1.56
Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection. J Infect Dis (2013) 1.42
Cross-sectional characterization of HIV-1 env compartmentalization in cerebrospinal fluid over the full disease course. AIDS (2009) 1.40
Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol (2008) 1.32
Neurologic and neurodevelopmental manifestations of pediatric HIV/AIDS: a global perspective. Eur J Paediatr Neurol (2006) 1.31
HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients. AIDS (2007) 1.25
Gene expression profiling of the preclinical scrapie-infected hippocampus. Biochem Biophys Res Commun (2005) 1.21
The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice. Kidney Int (2011) 1.16
Isotope ratios of H, C, and O in CO2 and H2O of the martian atmosphere. Science (2013) 1.15
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Hum Mol Genet (2006) 1.14
Identification of Plet-1 as a specific marker of early thymic epithelial progenitor cells. Proc Natl Acad Sci U S A (2008) 1.13
Impact of a focussed teaching programme on practical prescribing skills among final year medical students. Br J Clin Pharmacol (2011) 1.09
Macrophages expressing heme oxygenase-1 improve renal function in ischemia/reperfusion injury. Mol Ther (2010) 1.08
Urinary endothelin-1 in chronic kidney disease and as a marker of disease activity in lupus nephritis. Am J Physiol Renal Physiol (2009) 1.06
HIV DNA and dementia in treatment-naïve HIV-1-infected individuals in Bangkok, Thailand. Int J Med Sci (2006) 1.04
HIV-associated cognitive impairment in sub-Saharan Africa--the potential effect of clade diversity. Nat Clin Pract Neurol (2007) 1.03
Inflammatory cells in renal injury and repair. Semin Nephrol (2007) 1.02
Bone-marrow-derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis. Mol Ther (2002) 1.01
Hemeoxygenase-1 and renal ischaemia-reperfusion injury. Nephron Exp Nephrol (2010) 1.01
Inhibition of macrophage nuclear factor-kappaB leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo. Am J Pathol (2005) 1.00
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems. BMC Syst Biol (2010) 0.98
Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy. J Neurovirol (2013) 0.95
Digital clocks: simple Boolean models can quantitatively describe circadian systems. J R Soc Interface (2012) 0.94
Assessment of human papillomavirus mRNA detection over time in cervical specimens collected in liquid based cytology medium. J Virol Methods (2004) 0.92
Global NeuroAIDS roundtable. J Neurovirol (2013) 0.92
Randomized trial of minocycline in the treatment of HIV-associated cognitive impairment. Neurology (2012) 0.91
Macrophage heterogeneity in renal inflammation. Nephrol Dial Transplant (2003) 0.89
Endothelin-1 and the kidney--beyond BP. Br J Pharmacol (2012) 0.88
Immunosuppression for membranous nephropathy. Lancet (2013) 0.86
Human cytomegalovirus UL7, a homologue of the SLAM-family receptor CD229, impairs cytokine production. Immunol Cell Biol (2011) 0.85
Computed tomography angiography in the diagnosis of ANCA-associated small- and medium-vessel vasculitis. Am J Kidney Dis (2013) 0.85
NeuroAIDS in the Asia Pacific Region. J Neurovirol (2008) 0.84
Survival of a tertiary relict species, Liriodendron chinense (Magnoliaceae), in southern China, with special reference to village fengshui forests. Am J Bot (2013) 0.84
Motor based assessment of neurocognitive functioning in resource-limited international settings. J Clin Exp Neuropsychol (2007) 0.83
A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway. Biochem Pharmacol (2013) 0.82
Longitudinal neuropsychological test performance among HIV seropositive individuals in Uganda. J Neurovirol (2013) 0.82
HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda. Metab Brain Dis (2014) 0.82
The utility of the additive EuroSCORE, RIFLE and AKIN staging scores in the prediction and diagnosis of acute kidney injury after cardiac surgery. Nephron Clin Pract (2014) 0.81
Protein changes in CSF of HIV-infected patients: evidence for loss of neuroprotection. J Neurovirol (2011) 0.81
Peripheral neuropathy in primary HIV infection associates with systemic and central nervous system immune activation. J Acquir Immune Defic Syndr (2014) 0.80
Regulatory T cells: a brake on ischemic injury or an active promoter of tissue healing? Kidney Int (2009) 0.80
Humoral immune response and protection from viral infection in mice vaccinated with inactivated MHV-68: effects of type I interferon. J Interferon Cytokine Res (2002) 0.80
Factors that are associated with injury to the inferior alveolar nerve in high-risk patients after removal of third molars. Br J Oral Maxillofac Surg (2013) 0.79
Belimumab for systemic lupus erythematosus. Lancet (2011) 0.79
Evolving clinical phenotypes in HIV-associated neurocognitive disorders. Curr Opin HIV AIDS (2014) 0.79
Phenology of temperate trees in tropical climates. Int J Biometeorol (2005) 0.79
Endothelin antagonism and its role in the treatment of hypertension. Curr Hypertens Rep (2013) 0.78
Longitudinal characterization of depression and mood states beginning in primary HIV infection. AIDS Behav (2014) 0.78
Endothelin receptor antagonism and renin inhibition as treatment options for scleroderma kidney. Am J Kidney Dis (2009) 0.78
Recurrent ANCA-associated vasculitis after renal transplantation. Transplantation (2010) 0.78
Hemin Preconditioning Upregulates Heme Oxygenase-1 in Deceased Donor Renal Transplant Recipients: A Randomized, Controlled, Phase IIB Trial. Transplantation (2016) 0.77
Meeting review: Bioinformatics of biochips: accelerating discovery in functional genomics. Comp Funct Genomics (2002) 0.77
Computational modelling of atherosclerosis. Brief Bioinform (2015) 0.76
Inferring Boolean networks with perturbation from sparse gene expression data: a general model applied to the interferon regulatory network. Mol Biosyst (2008) 0.76
Oxidative stress promotes hypertension and albuminuria during the autoimmune disease systemic lupus erythematosus. Hypertension (2012) 0.76
Neurological complications of HIV infection and AIDS: current and future perspectives. J Neurovirol (2005) 0.76
Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis. Nucleic Acids Res (2013) 0.75
Editorial comment: déjà vu--neurologic complications of HIV infection in the expanding epidemic. AIDS Read (2005) 0.75
Paradoxical effects of heme arginate on survival of myocutaneous flaps. Am J Physiol Regul Integr Comp Physiol (2013) 0.75
TWEAK: a novel biomarker for lupus nephritis? Arthritis Res Ther (2009) 0.75
Enhancement of PAH biomineralization rates by cyclodextrins under Fe(III)-reducing conditions. Chemosphere (2005) 0.75
Impact of aging on neurocognitive performance in previously antiretroviral-naïve HIV+ individuals on their first suppressive regimen. AIDS (2017) 0.75
Possibility of charge contrast imaging of polymeric materials. Scanning (2004) 0.75