|
1
|
DNAzyme targeting c-jun suppresses skin cancer growth.
|
Sci Transl Med
|
2012
|
3.09
|
|
2
|
Insulin resistance is a cellular antioxidant defense mechanism.
|
Proc Natl Acad Sci U S A
|
2009
|
2.60
|
|
3
|
Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis.
|
Crit Care Med
|
2011
|
2.27
|
|
4
|
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice.
|
Gene
|
2007
|
2.24
|
|
5
|
Kynurenine is an endothelium-derived relaxing factor produced during inflammation.
|
Nat Med
|
2010
|
2.12
|
|
6
|
Association between both lipid and protein oxidation and the risk of fatal or non-fatal coronary heart disease in a human population.
|
Clin Sci (Lond)
|
2009
|
1.59
|
|
7
|
Serum amyloid A in uremic HDL promotes inflammation.
|
J Am Soc Nephrol
|
2012
|
1.27
|
|
8
|
Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.27
|
|
9
|
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis.
|
Am J Pathol
|
2002
|
1.18
|
|
10
|
Post-translational regulation of human indoleamine 2,3-dioxygenase activity by nitric oxide.
|
J Biol Chem
|
2007
|
1.16
|
|
11
|
Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging.
|
J Exp Med
|
2006
|
1.16
|
|
12
|
The heme environment of recombinant human indoleamine 2,3-dioxygenase. Structural properties and substrate-ligand interactions.
|
J Biol Chem
|
2002
|
1.14
|
|
13
|
Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase.
|
J Biol Chem
|
2009
|
1.08
|
|
14
|
Characterization of specifically oxidized apolipoproteins in mildly oxidized high density lipoprotein.
|
J Lipid Res
|
2002
|
1.08
|
|
15
|
Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells.
|
J Biol Chem
|
2008
|
1.08
|
|
16
|
Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration.
|
Biochem Pharmacol
|
2006
|
1.07
|
|
17
|
Probucol protects against smooth muscle cell proliferation by upregulating heme oxygenase-1.
|
Circulation
|
2004
|
1.05
|
|
18
|
Pharmacologic induction of heme oxygenase-1.
|
Antioxid Redox Signal
|
2007
|
1.04
|
|
19
|
Actions of "antioxidants" in the protection against atherosclerosis.
|
Free Radic Biol Med
|
2012
|
1.03
|
|
20
|
Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins.
|
Atherosclerosis
|
2008
|
1.03
|
|
21
|
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria.
|
J Infect Dis
|
2002
|
1.03
|
|
22
|
Hydrogen peroxide promotes endothelial dysfunction by stimulating multiple sources of superoxide anion radical production and decreasing nitric oxide bioavailability.
|
Cell Physiol Biochem
|
2007
|
1.02
|
|
23
|
Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria.
|
J Infect Dis
|
2003
|
1.01
|
|
24
|
Heme moves to center stage in cerebral malaria.
|
Nat Med
|
2007
|
1.01
|
|
25
|
The role of vitamin E in atherosclerosis.
|
Prog Lipid Res
|
2003
|
1.00
|
|
26
|
New insights into intracellular locations and functions of heme oxygenase-1.
|
Antioxid Redox Signal
|
2014
|
0.97
|
|
27
|
Low levels of docosahexaenoic acid identified in acute coronary syndrome patients with depression.
|
Psychiatry Res
|
2006
|
0.97
|
|
28
|
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases.
|
Free Radic Biol Med
|
2012
|
0.96
|
|
29
|
Probucol promotes functional reendothelialization in balloon-injured rabbit aortas.
|
Circulation
|
2003
|
0.96
|
|
30
|
Lack of the antioxidant glutathione peroxidase-1 does not increase atherosclerosis in C57BL/J6 mice fed a high-fat diet.
|
J Lipid Res
|
2006
|
0.95
|
|
31
|
Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme oxygenase-1.
|
Free Radic Biol Med
|
2013
|
0.95
|
|
32
|
Increased glycosphingolipid levels in serum and aortae of apolipoprotein E gene knockout mice.
|
J Lipid Res
|
2002
|
0.95
|
|
33
|
The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues.
|
Biochemistry
|
2010
|
0.95
|
|
34
|
Quinine-induced thrombocytopenia: drug-dependent GPIb/IX antibodies inhibit megakaryocyte and proplatelet production in vitro.
|
Blood
|
2011
|
0.94
|
|
35
|
Improved analysis of hydroethidine and 2-hydroxyethidium by HPLC and electrochemical detection.
|
Free Radic Biol Med
|
2007
|
0.93
|
|
36
|
Formation of methionine sulfoxide-containing specific forms of oxidized high-density lipoproteins.
|
Biochim Biophys Acta
|
2004
|
0.93
|
|
37
|
Heme oxygenase-1 increases endothelial progenitor cells.
|
Arterioscler Thromb Vasc Biol
|
2009
|
0.93
|
|
38
|
Flavivirus infection induces indoleamine 2,3-dioxygenase in human monocyte-derived macrophages via tumor necrosis factor and NF-κB.
|
J Leukoc Biol
|
2012
|
0.93
|
|
39
|
Cosupplementation with vitamin E and coenzyme Q10 reduces circulating markers of inflammation in baboons.
|
Am J Clin Nutr
|
2004
|
0.92
|
|
40
|
Haem oxygenase-1 and cardiovascular disease: mechanisms and therapeutic potential.
|
Clin Sci (Lond)
|
2011
|
0.90
|
|
41
|
Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells.
|
Blood
|
2010
|
0.89
|
|
42
|
Probucol inhibits in-stent thrombosis and neointimal hyperplasia by promoting re-endothelialization.
|
Atherosclerosis
|
2006
|
0.88
|
|
43
|
The use of antioxidant supplements in coronary heart disease.
|
Atherosclerosis
|
2002
|
0.87
|
|
44
|
A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL.
|
J Lipid Res
|
2008
|
0.86
|
|
45
|
Quercetin and its metabolites improve vessel function by inducing eNOS activity via phosphorylation of AMPK.
|
Biochem Pharmacol
|
2012
|
0.86
|
|
46
|
Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development.
|
Adv Hematol
|
2011
|
0.86
|
|
47
|
Protective effect of vitamin E supplements on experimental atherosclerosis is modest and depends on preexisting vitamin E deficiency.
|
Free Radic Biol Med
|
2006
|
0.86
|
|
48
|
Intimal thickening after arterial balloon injury is increased by intermittent repetitive hypoxia, but intermittent repetitive hyperoxia is not protective.
|
Atherosclerosis
|
2005
|
0.85
|
|
49
|
Vitamin E oxidation in human atherosclerotic lesions.
|
Circ Res
|
2002
|
0.84
|
|
50
|
Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE(-/-) mice from the development of atherosclerosis.
|
Cardiovasc Pathol
|
2012
|
0.84
|
|
51
|
Human S-nitroso oxymyoglobin is a store of vasoactive nitric oxide.
|
J Biol Chem
|
2005
|
0.84
|
|
52
|
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis.
|
Diabetes
|
2013
|
0.84
|
|
53
|
Maternal undernutrition reduces aortic wall thickness and elastin content in offspring rats without altering endothelial function.
|
Clin Sci (Lond)
|
2006
|
0.84
|
|
54
|
The yeast homolog of heme oxygenase-1 affords cellular antioxidant protection via the transcriptional regulation of known antioxidant genes.
|
J Biol Chem
|
2010
|
0.84
|
|
55
|
Biomarkers of Oxidative Stress Study IV: ozone exposure of rats and its effect on antioxidants in plasma and bronchoalveolar lavage fluid.
|
Free Radic Biol Med
|
2011
|
0.84
|
|
56
|
Evidence that phospholipids play a key role in pre-beta apoA-I formation and high-density lipoprotein remodeling.
|
Biochemistry
|
2002
|
0.84
|
|
57
|
The lipophilic antioxidants alpha-tocopherol and coenzyme Q10 reduce the replicative lifespan of Saccharomyces cerevisiae.
|
Free Radic Biol Med
|
2010
|
0.84
|
|
58
|
Plasmodium falciparum histidine-rich protein-2 (PfHRP2) modulates the redox activity of ferri-protoporphyrin IX (FePPIX): peroxidase-like activity of the PfHRP2-FePPIX complex.
|
J Biol Chem
|
2002
|
0.83
|
|
59
|
Oxidized lipid accumulates in the presence of alpha-tocopherol in atherosclerosis.
|
Biochem J
|
2002
|
0.83
|
|
60
|
The endothelium-derived hyperpolarizing factor, H2O2, promotes metal-ion efflux in aortic endothelial cells: elemental mapping by a hard X-ray microprobe.
|
Biochemistry
|
2006
|
0.83
|
|
61
|
Heme oxygenase and iron: from bacteria to humans.
|
Redox Rep
|
2009
|
0.82
|
|
62
|
Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation.
|
FASEB J
|
2013
|
0.82
|
|
63
|
Processes involved in the site-specific effect of probucol on atherosclerosis in apolipoprotein E gene knockout mice.
|
Arterioscler Thromb Vasc Biol
|
2005
|
0.82
|
|
64
|
Extended-duration thromboprophylaxis with enoxaparin after arthroscopic surgery of the anterior cruciate ligament: a prospective, randomized, placebo-controlled study.
|
Arthroscopy
|
2007
|
0.81
|
|
65
|
Probucol [4,4'-[(1-methylethylidene)bis(thio)]bis-[2,6-bis(1,1-dimethylethyl)phenol]] inhibits compensatory remodeling and promotes lumen loss associated with atherosclerosis in apolipoprotein E-deficient mice.
|
J Pharmacol Exp Ther
|
2007
|
0.81
|
|
66
|
Equivalent lipid oxidation profiles in advanced atherosclerotic lesions of carotid endarterectomy plaques obtained from symptomatic type 2 diabetic and nondiabetic subjects.
|
Free Radic Biol Med
|
2010
|
0.80
|
|
67
|
Retracted
Angiotensin II-inducible smooth muscle cell apoptosis involves the angiotensin II type 2 receptor, GATA-6 activation, and FasL-Fas engagement.
|
Circ Res
|
2009
|
0.80
|
|
68
|
Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia.
|
Circ Res
|
2010
|
0.80
|
|
69
|
Assessment of myeloperoxidase activity by the conversion of hydroethidine to 2-chloroethidium.
|
J Biol Chem
|
2014
|
0.80
|
|
70
|
Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits.
|
Atherosclerosis
|
2002
|
0.78
|
|
71
|
A phosphatidylcholine-BODIPY 581/591 conjugate allows mapping of oxidative stress in P. falciparum-infected erythrocytes.
|
Cytometry A
|
2009
|
0.78
|
|
72
|
Anti-atherosclerotic and anti-diabetic properties of probucol and related compounds.
|
Redox Rep
|
2008
|
0.78
|
|
73
|
Sustained expression of heme oxygenase-1 alters iron homeostasis in nonerythroid cells.
|
Free Radic Biol Med
|
2012
|
0.78
|
|
74
|
Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.
|
Naunyn Schmiedebergs Arch Pharmacol
|
2011
|
0.78
|
|
75
|
Determination of the nature of the heme environment in nitrosyl indoleamine 2,3-dioxygenase using Multiple-scattering analyses of X-ray absorption fine structure.
|
Biochemistry
|
2004
|
0.77
|
|
76
|
Is hypochlorous acid (HOCl) involved in age-related nuclear cataract?
|
Clin Exp Optom
|
2002
|
0.77
|
|
77
|
Coenzyme Q(10) supplementation inhibits aortic lipid oxidation but fails to attenuate intimal thickening in balloon-injured New Zealand white rabbits.
|
Free Radic Biol Med
|
2003
|
0.76
|
|
78
|
Oxidant stress and damage in post-ischemic mouse hearts: effects of adenosine.
|
Mol Cell Biochem
|
2006
|
0.76
|
|
79
|
Succinobucol induces apoptosis in vascular smooth muscle cells.
|
Free Radic Biol Med
|
2011
|
0.76
|
|
80
|
Probucol protects against hypochlorite-induced endothelial dysfunction: identification of a novel pathway of probucol oxidation to a biologically active intermediate.
|
J Biol Chem
|
2005
|
0.76
|
|
81
|
Regio- and stereo-chemical oxidation of linoleic acid by human myoglobin and hydrogen peroxide: Tyr(103) affects rate and product distribution.
|
Biochem J
|
2004
|
0.76
|
|
82
|
Simultaneous determination of coenzyme Q10, cholesterol, and major cholesterylesters in human blood plasma.
|
Methods Enzymol
|
2004
|
0.76
|
|
83
|
Lack of inhibitory effect of HDL on TNFalpha-induced adhesion molecule expression in human aortic endothelial cells.
|
Atherosclerosis
|
2002
|
0.75
|
|
84
|
Vitamin E is not deficient in human atherosclerotic plaques.
|
Arterioscler Thromb Vasc Biol
|
2004
|
0.75
|
|
85
|
CoQ₁₀ Function and Role in Heart Failure and Ischemic Heart Disease.
|
Annu Rev Nutr
|
2015
|
0.75
|
|
86
|
Correction: AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation.
|
PLoS One
|
2016
|
0.75
|
|
87
|
Destroying c-jun Messenger: new insights into biological mechanisms of DNAzyme function.
|
Oncotarget
|
2012
|
0.75
|
|
88
|
The benefit of coenzyme Q10 supplements in the management of chronic heart failure: a long tale of promise in the continued absence of clear evidence.
|
Am J Clin Nutr
|
2013
|
0.75
|
|
89
|
Regulation of vascular tone by S-nitroso-myoglobin.
|
Redox Rep
|
2004
|
0.75
|
|
90
|
Transition to 37°C reveals importance of NADPH in mitigating oxidative stress in stored RBCs.
|
JCI Insight
|
2019
|
0.75
|
|
91
|
Characterization of the oxidation products of BO-653 formed during peroxyl radical-mediated oxidation of human plasma.
|
Free Radic Biol Med
|
2005
|
0.75
|
|
92
|
Detection of specifically oxidized apolipoproteins in oxidized HDL.
|
Methods Mol Biol
|
2008
|
0.75
|
|
93
|
Vascular microdissection, perfusion, and excision of the murine arterial tree for use in atherogenic disease investigations.
|
Contemp Top Lab Anim Sci
|
2003
|
0.75
|