Published in IUBMB Life on February 24, 2011
Mitochondria and cancer. Nat Rev Cancer (2012) 4.81
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations. J Clin Invest (2013) 3.55
miR-210: the master hypoxamir. Microcirculation (2012) 1.56
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock. Cell (2015) 1.51
MicroRNA dysregulation in diabetic ischemic heart failure patients. Diabetes (2012) 1.31
The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness. Biochim Biophys Acta (2012) 1.26
MIR-210 modulates mitochondrial respiration in placenta with preeclampsia. Placenta (2012) 1.26
Hypoxia induced aggressiveness of prostate cancer cells is linked with deregulated expression of VEGF, IL-6 and miRNAs that are attenuated by CDF. PLoS One (2012) 1.18
MicroRNAs and their target genes in gingival tissues. J Dent Res (2012) 1.14
Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. RNA (2012) 1.13
Multiple functions of hypoxia-regulated miR-210 in cancer. J Exp Clin Cancer Res (2014) 1.12
Oxidative stress and microRNAs in vascular diseases. Int J Mol Sci (2013) 1.10
microRNAs: innovative targets for cerebral ischemia and stroke. Curr Drug Targets (2013) 1.10
Regulatory mechanisms and clinical perspectives of miRNA in tumor radiosensitivity. Carcinogenesis (2012) 1.10
MicroRNA signatures in tumor tissue related to angiogenesis in non-small cell lung cancer. PLoS One (2012) 1.07
MicroRNAs in skeletal muscle and their regulation with exercise, ageing, and disease. Front Physiol (2013) 1.00
MicroRNAs in Human Placental Development and Pregnancy Complications. Int J Mol Sci (2013) 1.00
Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment. PLoS One (2012) 0.98
miR-210: fine-tuning the hypoxic response. Adv Exp Med Biol (2014) 0.95
Hypoxia-inducible factor 1-α induces miR-210 in normoxic differentiating myoblasts. J Biol Chem (2012) 0.95
HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts. Cell Death Differ (2013) 0.94
Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment. DNA Repair (Amst) (2015) 0.93
HypoxamiRs and cancer: from biology to targeted therapy. Antioxid Redox Signal (2013) 0.92
ROD1 is a seedless target gene of hypoxia-induced miR-210. PLoS One (2012) 0.92
The role of hypoxia-induced miR-210 in cancer progression. Int J Mol Sci (2015) 0.91
The non-coding RNAs of the H19-IGF2 imprinted loci: a focus on biological roles and therapeutic potential in Lung Cancer. J Transl Med (2015) 0.89
"Seed-Milarity" confers to hsa-miR-210 and hsa-miR-147b similar functional activity. PLoS One (2012) 0.89
Regulation of Aerobic Glycolysis by microRNAs in Cancer. Mol Cell Pharmacol (2011) 0.89
MicroRNA in diabetic nephropathy: renin angiotensin, aGE/RAGE, and oxidative stress pathway. J Diabetes Res (2013) 0.88
miRNAs as potential therapeutic targets for age-related macular degeneration. Future Med Chem (2012) 0.87
Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia. Cancer Sci (2014) 0.87
Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity. Int J Obes (Lond) (2015) 0.86
MicroRNAs in placental health and disease. Am J Obstet Gynecol (2015) 0.85
MicroRNA response to hypoxic stress in soft tissue sarcoma cells: microRNA mediated regulation of HIF3α. BMC Cancer (2014) 0.84
Interplay Between Metabolism and Oncogenic Process: Role of microRNAs. Transl Oncogenomics (2015) 0.84
MicroRNAs in Hypoxia Response. Antioxid Redox Signal (2014) 0.83
OxymiRs in cutaneous development, wound repair and regeneration. Semin Cell Dev Biol (2012) 0.83
Overexpression of miR-210 is Associated with Poor Prognosis of Acute Myeloid Leukemia. Med Sci Monit (2015) 0.82
Unique microRNAs in lung adenocarcinoma groups according to major TKI sensitive EGFR mutation status. Diagn Pathol (2015) 0.82
PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells. Oncotarget (2014) 0.82
miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1. Mol Cancer (2015) 0.82
Targeting CSCs in tumor microenvironment: the potential role of ROS-associated miRNAs in tumor aggressiveness. Curr Stem Cell Res Ther (2014) 0.81
Hypoxia-induced miR-210 modulates tissue response to acute peripheral ischemia. Antioxid Redox Signal (2013) 0.81
Meta-analysis using a novel database, miRStress, reveals miRNAs that are frequently associated with the radiation and hypoxia stress-responses. PLoS One (2013) 0.81
Up-regulation of microRNA-210 inhibits proliferation of hepatocellular carcinoma cells by targeting YES1. World J Gastroenterol (2015) 0.81
MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury. J Am Soc Nephrol (2016) 0.80
Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. Neurochem Res (2016) 0.78
Adipose tissue dysfunction and its effects on tumor metabolism. Horm Mol Biol Clin Investig (2015) 0.77
Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy. Clin Epigenetics (2011) 0.77
Potential Role of MicroRNA-210 as Biomarker in Human Cancers Detection: A Meta-Analysis. Biomed Res Int (2015) 0.77
Predictive value of miR-210 as a novel biomarker for pre-eclampsia: a systematic review protocol. BMJ Open (2016) 0.76
Up-Regulation of microRNA-210 is Associated with Spermatogenesis by Targeting IGF2 in Male Infertility. Med Sci Monit (2016) 0.76
Involvement of miRNAs in placental alterations mediated by oxidative stress. Oxid Med Cell Longev (2014) 0.76
miR-199a-5p regulates HIF-1α and OSGIN2 and its expression is correlated to soft-tissue sarcoma patients' outcome. Oncol Lett (2016) 0.75
Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors. Oncotarget (2016) 0.75
Making sense in antisense: therapeutic potential of noncoding RNAs in diabetes-induced vascular dysfunction. J Diabetes Res (2013) 0.75
MiR-210 promotes sensory hair cell formation in the organ of corti. BMC Genomics (2016) 0.75
HMGB1 induces apoptosis and EMT in association with increased autophagy following H/R injury in cardiomyocytes. Int J Mol Med (2016) 0.75
Role of microRNA-210 in human intervertebral disc degeneration. Exp Ther Med (2016) 0.75
The accuracy of microRNA-210 in diagnosing lung cancer: a systematic review and meta-analysis. Oncotarget (2016) 0.75
Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. J Immunol (2016) 0.75
Retinal and Circulating miRNAs in Age-Related Macular Degeneration: An In vivo Animal and Human Study. Front Pharmacol (2017) 0.75
NPC-EXs Alleviate Endothelial Oxidative Stress and Dysfunction through the miR-210 Downstream Nox2 and VEGFR2 Pathways. Oxid Med Cell Longev (2017) 0.75
Intra-articular injection of synthetic microRNA-210 accelerates avascular meniscal healing in rat medial meniscal injured model. Arthritis Res Ther (2014) 0.75
Mitochondrial composition and function under the control of hypoxia. Redox Biol (2017) 0.75
Oxygen levels and the regulation of cell adhesion in the nervous system: a control point for morphogenesis in development, disease and evolution? Cell Adh Migr (2012) 0.75
Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. Hum Mol Genet (2017) 0.75
Elevation of Circulating miR-210-3p in High-Altitude Hypoxic Environment. Front Physiol (2016) 0.75
Development of a circulating miRNA assay to monitor tumor burden: From mouse to man. Mol Oncol (2015) 0.75
MicroRNA-210 contributes to peripheral nerve regeneration through promoting the proliferation and migration of Schwann cells. Exp Ther Med (2017) 0.75
Maintenance of redox homeostasis by hypoxia-inducible factors. Redox Biol (2017) 0.75
MicroRNA-210-mediated proliferation, survival, and angiogenesis promote cardiac repair post myocardial infarction in rodents. J Mol Med (Berl) (2017) 0.75
Circulating microRNAs in malaria infection: bench to bedside. Malar J (2017) 0.75
A microRNA signature of hypoxia. Mol Cell Biol (2006) 7.24
MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. J Biol Chem (2008) 4.69
Circulating microRNAs are new and sensitive biomarkers of myocardial infarction. Eur Heart J (2010) 4.47
Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling. Science (2002) 3.86
MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res (2009) 2.93
MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation (2010) 2.32
Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia. FASEB J (2009) 2.22
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS One (2010) 2.05
Deregulation of microRNA-503 contributes to diabetes mellitus-induced impairment of endothelial function and reparative angiogenesis after limb ischemia. Circulation (2011) 1.99
Hypoxia response and microRNAs: no longer two separate worlds. J Cell Mol Med (2008) 1.93
An integrated approach for experimental target identification of hypoxia-induced miR-210. J Biol Chem (2009) 1.90
HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. Proc Natl Acad Sci U S A (2008) 1.80
Microrna-221 and microrna-222 modulate differentiation and maturation of skeletal muscle cells. PLoS One (2009) 1.79
Enhanced arteriogenesis and wound repair in dystrophin-deficient mdx mice. Circulation (2004) 1.73
Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. Proc Natl Acad Sci U S A (2006) 1.66
p66ShcA modulates oxidative stress and survival of endothelial progenitor cells in response to high glucose. Cardiovasc Res (2009) 1.62
Regulatory mechanisms of microRNAs involvement in cancer. Expert Opin Biol Ther (2007) 1.57
Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol Cell (2003) 1.55
Regulation of microRNA expression: the hypoxic component. Cell Cycle (2007) 1.49
p21(Waf1/Cip1/Sdi1) mediates shear stress-dependent antiapoptotic function. Cardiovasc Res (2004) 1.48
microRNA: emerging therapeutic targets in acute ischemic diseases. Pharmacol Ther (2009) 1.45
p66ShcA modulates tissue response to hindlimb ischemia. Circulation (2004) 1.43
MicroRNA dysregulation in diabetic ischemic heart failure patients. Diabetes (2012) 1.31
p66(ShcA) and oxidative stress modulate myogenic differentiation and skeletal muscle regeneration after hind limb ischemia. J Biol Chem (2007) 1.27
Oxidative stress and epigenetic regulation in ageing and age-related diseases. Int J Mol Sci (2013) 1.25
Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling. Circ Res (2007) 1.24
MicroRNA signatures in peripheral blood mononuclear cells of chronic heart failure patients. Physiol Genomics (2010) 1.17
Emerging roles of microRNAs in the molecular responses to hypoxia. Curr Pharm Des (2009) 1.14
Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. RNA (2012) 1.13
Dysregulation and cellular mislocalization of specific miRNAs in myotonic dystrophy type 1. Neuromuscul Disord (2010) 1.13
MyoD stimulates RB promoter activity via the CREB/p300 nuclear transduction pathway. Mol Cell Biol (2003) 1.10
Oxidative stress and microRNAs in vascular diseases. Int J Mol Sci (2013) 1.10
A randomized pilot trial comparing cyclosporine and azathioprine for maintenance therapy in diffuse lupus nephritis over four years. Clin J Am Soc Nephrol (2006) 1.09
Oxidative stress induces protein phosphatase 2A-dependent dephosphorylation of the pocket proteins pRb, p107, and p130. J Biol Chem (2003) 1.08
microRNAs in cancer: from bench to bedside. Adv Cancer Res (2010) 1.08
Transcription factor NF-Y induces apoptosis in cells expressing wild-type p53 through E2F1 upregulation and p53 activation. Cancer Res (2010) 1.07
Post-Transcriptional Control of the Hypoxic Response by RNA-Binding Proteins and MicroRNAs. Front Mol Neurosci (2011) 1.06
Impaired T- and B-cell development in Tcl1-deficient mice. Blood (2004) 1.04
Protein phosphatase 2A subunit PR70 interacts with pRb and mediates its dephosphorylation. Mol Cell Biol (2007) 1.04
Hypoxia inhibits myogenic differentiation through accelerated MyoD degradation. J Biol Chem (2004) 1.04
Dihydroceramide-based response to hypoxia. J Biol Chem (2011) 1.02
Deregulated microRNAs in myotonic dystrophy type 2. PLoS One (2012) 1.01
Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth. Mol Cancer Ther (2011) 1.00
Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle. J Biol Chem (2011) 0.99
Platelet-derived growth factor-receptor alpha strongly inhibits melanoma growth in vitro and in vivo. Neoplasia (2009) 0.98
microRNAs as peripheral blood biomarkers of cardiovascular disease. Vascul Pharmacol (2011) 0.97
PDGF induced microRNA alterations in cancer cells. Nucleic Acids Res (2011) 0.97
Proteasome-dependent regulation of signal transduction in retinal pigment epithelial cells. Exp Eye Res (2006) 0.95
Hypoxia-inducible factor 1-α induces miR-210 in normoxic differentiating myoblasts. J Biol Chem (2012) 0.95
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts. J Mol Med (Berl) (2013) 0.95
MicroRNA-155 targets the SKI gene in human melanoma cell lines. Pigment Cell Melanoma Res (2011) 0.93
HypoxamiRs and cancer: from biology to targeted therapy. Antioxid Redox Signal (2013) 0.92
Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress. FASEB J (2006) 0.92
PKC-zeta is required for angiotensin II-induced activation of ERK and synthesis of C-FOS in MCF-7 cells. J Cell Physiol (2003) 0.92
ROD1 is a seedless target gene of hypoxia-induced miR-210. PLoS One (2012) 0.92
A nitric oxide-dependent cross-talk between class I and III histone deacetylases accelerates skin repair. J Biol Chem (2013) 0.91
AMP-activated protein kinase is essential for survival in chronic hypoxia. Biochem Biophys Res Commun (2008) 0.89
Regulation of the endothelial cell cycle by the ubiquitin-proteasome system. Cardiovasc Res (2009) 0.89
Molecular mechanisms of cardiomyocyte regeneration and therapeutic outlook. Trends Mol Med (2007) 0.88
Analysis of von Hippel-Lindau hereditary cancer syndrome: implications of oxygen sensing. Methods Enzymol (2004) 0.87
HypoxamiR regulation and function in ischemic cardiovascular diseases. Antioxid Redox Signal (2013) 0.87
Characterization of phosphorylation sites on Tpl2 using IMAC enrichment and a linear ion trap mass spectrometer. J Proteome Res (2007) 0.86
Activation of P2Y2 receptor induces c-FOS protein through a pathway involving mitogen-activated protein kinases and phosphoinositide 3-kinases in HeLa cells. J Cell Physiol (2003) 0.86
Identification of Elongin C and Skp1 sequences that determine Cullin selection. J Biol Chem (2004) 0.85
Flavopiridol-induced apoptosis during S phase requires E2F-1 and inhibition of cyclin A-dependent kinase activity. Cancer Res (2003) 0.84
MicroRNAs in Hypoxia Response. Antioxid Redox Signal (2014) 0.83
Activation of P2Y2 purinoceptor inhibits the activity of the Na+/K+-ATPase in HeLa cells. Cell Signal (2003) 0.81
Hypoxia-induced miR-210 modulates tissue response to acute peripheral ischemia. Antioxid Redox Signal (2013) 0.81
Transcriptional profiling of HMGB1-induced myocardial repair identifies a key role for Notch signaling. Mol Ther (2013) 0.81
Increase of [Ca(2+)](i) via activation of ATP receptors in PC-Cl3 rat thyroid cell line. Cell Signal (2002) 0.80
Papilloma protein E6 abrogates shear stress-dependent survival in human endothelial cells: evidence for specialized functions of paxillin. Cardiovasc Res (2006) 0.80
Targeting the insulin growth factor and the vascular endothelial growth factor pathways in ovarian cancer. Mol Cancer Ther (2012) 0.79
Differential signalling of purinoceptors in HeLa cells through the extracellular signal-regulated kinase and protein kinase C pathways. J Cell Physiol (2004) 0.79
Disturbances in purinergic [Ca2+]i signaling pathways in a transformed rat thyroid cell line. Cell Calcium (2003) 0.78
Effects of extracellular nucleotides in the thyroid: P2Y2 receptor-mediated ERK1/2 activation and c-Fos induction in PC Cl3 cells. Cell Signal (2004) 0.77
Characterizing the heterogeneity of triple-negative breast cancers using microdissected normal ductal epithelium and RNA-sequencing. Breast Cancer Res Treat (2013) 0.77
"Micro"-management of DNA repair genes by hypoxia. Cell Cycle (2009) 0.77
Enhancement of lysine acetylation accelerates wound repair. Commun Integr Biol (2013) 0.76
Removing the brakes to cardiomyocyte cell cycle. Cell Cycle (2011) 0.76
Molecular responses to hypoxia: ancient pathways, clinical promises. J Cell Mol Med (2009) 0.75
The ongoing microRNA revolution and its impact in biology and medicine. J Cell Mol Med (2008) 0.75
Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. Mol Cell (2016) 0.75