Ralph S Baric

Author PubWeight™ 161.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol 2013 4.98
2 Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med 2008 4.57
3 Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. J Virol 2002 4.29
4 Norwalk virus: how infectious is it? J Med Virol 2008 3.93
5 Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 2011 3.25
6 Binding of Norwalk virus-like particles to ABH histo-blood group antigens is blocked by antisera from infected human volunteers or experimentally vaccinated mice. J Virol 2002 2.98
7 Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 2003 2.82
8 Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission. J Virol 2009 2.60
9 Cellular and humoral immunity following Snow Mountain virus challenge. J Virol 2005 2.59
10 Viral shape-shifting: norovirus evasion of the human immune system. Nat Rev Microbiol 2010 2.53
11 Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc Natl Acad Sci U S A 2012 2.42
12 Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J Virol 2005 2.22
13 Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. J Virol 2007 2.18
14 Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci U S A 2014 2.17
15 Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. J Virol 2005 2.05
16 Immunogenetic mechanisms driving norovirus GII.4 antigenic variation. PLoS Pathog 2012 2.02
17 Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci U S A 2008 1.97
18 Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations. Immunol Rev 2008 1.96
19 A decade after SARS: strategies for controlling emerging coronaviruses. Nat Rev Microbiol 2013 1.94
20 Heterologous gene expression from transmissible gastroenteritis virus replicon particles. J Virol 2002 1.85
21 Norovirus capture with histo-blood group antigens reveals novel virus-ligand interactions. J Virol 2004 1.80
22 Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling. MBio 2010 1.79
23 Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J Virol 2007 1.75
24 Evidence supporting a zoonotic origin of human coronavirus strain NL63. J Virol 2012 1.75
25 Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains. Vaccine 2006 1.74
26 Norovirus GII.4 strain antigenic variation. J Virol 2010 1.73
27 Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 2013 1.73
28 The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. J Virol 2005 1.71
29 Heterotypic humoral and cellular immune responses following Norwalk virus infection. J Virol 2009 1.70
30 Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection. PLoS Pathog 2008 1.69
31 Antibody is critical for the clearance of murine norovirus infection. J Virol 2008 1.69
32 Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. J Virol 2013 1.68
33 Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing. PLoS Pathog 2010 1.67
34 Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. J Virol 2009 1.58
35 Natural strain variation and antibody neutralization of dengue serotype 3 viruses. PLoS Pathog 2010 1.56
36 Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice. J Virol 2005 1.54
37 Genetic mapping of a highly variable norovirus GII.4 blockade epitope: potential role in escape from human herd immunity. J Virol 2011 1.53
38 Herd immunity to GII.4 noroviruses is supported by outbreak patient sera. J Virol 2009 1.51
39 Emergence of new pandemic GII.4 Sydney norovirus strain correlates with escape from herd immunity. J Infect Dis 2013 1.47
40 MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. PLoS Pathog 2008 1.47
41 Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog 2013 1.43
42 Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus. MBio 2013 1.41
43 Cynomolgus macaque as an animal model for severe acute respiratory syndrome. PLoS Med 2006 1.40
44 Norovirus immunity and the great escape. PLoS Pathog 2012 1.40
45 Emergence of a norovirus GII.4 strain correlates with changes in evolving blockade epitopes. J Virol 2012 1.36
46 Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles. J Virol 2002 1.36
47 Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda) 2012 1.35
48 SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon. Curr Opin Virol 2012 1.33
49 A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge. J Virol 2011 1.32
50 Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication. J Virol 2004 1.32
51 SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. PLoS Pathog 2010 1.32
52 Monoclonal antibody-based antigenic mapping of norovirus GII.4-2002. J Virol 2011 1.29
53 A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Nat Med 2012 1.26
54 Norovirus infectivity in humans and persistence in water. Appl Environ Microbiol 2011 1.26
55 Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses. J Infect Dis 2013 1.23
56 Systematic assembly of a full-length infectious clone of human coronavirus NL63. J Virol 2008 1.23
57 Characterization of the homo- and heterotypic immune responses after natural norovirus infection. J Med Virol 2005 1.23
58 Processing of open reading frame 1a replicase proteins nsp7 to nsp10 in murine hepatitis virus strain A59 replication. J Virol 2007 1.22
59 Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: engineering a recombination-resistant genome. Proc Natl Acad Sci U S A 2006 1.22
60 Retracted Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity. Proc Natl Acad Sci U S A 2014 1.19
61 Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity. RNA Biol 2011 1.18
62 Characterization of emerging GII.g/GII.12 noroviruses from a gastroenteritis outbreak in the United States in 2010. J Clin Microbiol 2011 1.18
63 Alphavirus-adjuvanted norovirus-like particle vaccines: heterologous, humoral, and mucosal immune responses protect against murine norovirus challenge. J Virol 2009 1.17
64 Improved quality control processing of peptide-centric LC-MS proteomics data. Bioinformatics 2011 1.15
65 Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus. J Virol 2013 1.15
66 Development and characterization of a reverse genetic system for studying dengue virus serotype 3 strain variation and neutralization. PLoS Negl Trop Dis 2012 1.14
67 Novel influenza virus NS1 antagonists block replication and restore innate immune function. J Virol 2008 1.11
68 Mouse dipeptidyl peptidase 4 is not a functional receptor for Middle East respiratory syndrome coronavirus infection. J Virol 2014 1.11
69 Amino acid substitutions in the S2 subunit of mouse hepatitis virus variant V51 encode determinants of host range expansion. J Virol 2007 1.10
70 Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity. J Virol 2014 1.10
71 Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. J Virol 2013 1.08
72 Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease. J Virol 2011 1.07
73 Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. J Infect Dis 2010 1.07
74 Effect of mutations in the mouse hepatitis virus 3'(+)42 protein binding element on RNA replication. J Virol 2005 1.07
75 Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. J Virol 2010 1.07
76 Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis. J Virol 2007 1.06
77 Molecular pathology of emerging coronavirus infections. J Pathol 2015 1.05
78 Analysis of murine hepatitis virus strain A59 temperature-sensitive mutant TS-LA6 suggests that nsp10 plays a critical role in polyprotein processing. J Virol 2007 1.04
79 Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury. MBio 2013 1.04
80 Molecular surveillance of enterovirus and norwalk-like virus in oysters relocated to a municipal-sewage-impacted gulf estuary. Appl Environ Microbiol 2003 1.01
81 Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection. MBio 2011 1.01
82 Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. PLoS Pathog 2010 0.99
83 Characterization of blockade antibody responses in GII.2.1976 Snow Mountain virus-infected subjects. J Virol 2013 0.98
84 Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection. J Virol 2010 0.95
85 A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant. MBio 2014 0.95
86 mRNA display design of fibronectin-based intrabodies that detect and inhibit severe acute respiratory syndrome coronavirus nucleocapsid protein. J Biol Chem 2009 0.92
87 Identification of cross-reactive norovirus CD4+ T cell epitopes. J Virol 2010 0.91
88 Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth. J Virol 2009 0.89
89 SARS CoV replication and pathogenesis in human airway epithelial cultures. Adv Exp Med Biol 2006 0.89
90 A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses. PLoS One 2013 0.87
91 A novel mutation in murine hepatitis virus nsp5, the viral 3C-like proteinase, causes temperature-sensitive defects in viral growth and protein processing. J Virol 2008 0.87
92 Emerging human coronaviruses--disease potential and preparedness. N Engl J Med 2012 0.86
93 SARS coronavirus accessory ORFs encode luxury functions. Adv Exp Med Biol 2006 0.85
94 The nsp2 proteins of mouse hepatitis virus and SARS coronavirus are dispensable for viral replication. Adv Exp Med Biol 2006 0.83
95 The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death. J Virol 2009 0.83
96 Reverse genetic analysis of the transcription regulatory sequence of the coronavirus transmissible gastroenteritis virus. J Virol 2004 0.83
97 Non-Hodgkin lymphoma (NHL) subtypes defined by common translocations: utility of fluorescence in situ hybridization (FISH) in a case-control study. Leuk Res 2009 0.82
98 RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus. Nucleic Acids Res 2012 0.82
99 Protein co-expression network analysis (ProCoNA). J Clin Bioinforma 2013 0.82
100 Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b. Adv Exp Med Biol 2006 0.81
101 Renilla luciferase as a reporter to assess SARS-CoV mRNA transcription regulation and efficacy of anti-SARS-CoV agents. Adv Exp Med Biol 2006 0.81
102 A case-control study of tobacco use and other non-occupational risk factors for lymphoma subtypes defined by t(14; 18) translocations and bcl-2 expression. Cancer Causes Control 2010 0.80
103 Altering SARS coronavirus frameshift efficiency affects genomic and subgenomic RNA production. Viruses 2013 0.80
104 Systematic assembly and genetic manipulation of the mouse hepatitis virus A59 genome. Methods Mol Biol 2008 0.80
105 Association between herpes simplex virus type 1 and Helicobacter pylori in US adolescents. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006 0.79
106 The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1. Virology 2013 0.78
107 Detection of enteroviruses in shellfish by fluorogenic polymerase chain reaction integrated with 96-well microplate scanning. J AOAC Int 2002 0.78
108 Mutational analysis of MHV-A59 replicase protein-nsp10. Adv Exp Med Biol 2006 0.78
109 Bugs in the system. Immunol Rev 2013 0.78
110 Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques. PLoS One 2011 0.78
111 Spike gene determinants of mouse hepatitis virus host range expansion. Adv Exp Med Biol 2006 0.77
112 MHV-A59 ORF1a replicase protein nsp7-nsp10 processing in replication. Adv Exp Med Biol 2006 0.76
113 A Simulation Framework to Investigate in vitro Viral Infection Dynamics. J Comput Sci 2013 0.75
114 Dengue virus envelope protein domain I/II hinge: a key target for dengue virus vaccine design? Expert Rev Vaccines 2014 0.75
115 Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection. Emerg Infect Dis 2017 0.75
116 A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies. bioRxiv 2022 0.75
117 Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains. bioRxiv 2022 0.75
118 Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2. bioRxiv 2020 0.75
119 Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med 2016 0.75