Published in J Biol Chem on April 13, 2009
Adnectins: engineered target-binding protein therapeutics. Protein Eng Des Sel (2010) 1.07
Single-round, multiplexed antibody mimetic design through mRNA display. Angew Chem Int Ed Engl (2012) 0.98
Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov (2016) 0.91
Selection of proteins with desired properties from natural proteome libraries using mRNA display. Nat Protoc (2011) 0.88
Rapid mRNA-display selection of an IL-6 inhibitor using continuous-flow magnetic separation. Angew Chem Int Ed Engl (2011) 0.81
Streamlined protocol for mRNA display. ACS Comb Sci (2013) 0.77
High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin Domains. PLoS One (2015) 0.75
Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging. Front Immunol (2017) 0.75
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res (1987) 25.34
Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science (2003) 18.34
RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc Natl Acad Sci U S A (1997) 5.06
Potent antibody therapeutics by design. Nat Rev Immunol (2006) 4.87
Dissecting protein-protein recognition sites. Proteins (2002) 4.51
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2003) 2.82
The fibronectin type III domain as a scaffold for novel binding proteins. J Mol Biol (1998) 2.65
Optimized synthesis of RNA-protein fusions for in vitro protein selection. Methods Enzymol (2000) 2.00
In-vitro protein evolution by ribosome display and mRNA display. J Immunol Methods (2004) 1.69
Recombinant antibodies to the small GTPase Rab6 as conformation sensors. Science (2003) 1.40
Selection of antibodies for intracellular function using a two-hybrid in vivo system. Proc Natl Acad Sci U S A (1999) 1.38
Antibody engineering. Annu Rev Biomed Eng (2000) 1.37
Biochemical aspects of coronavirus replication and virus-host interaction. Annu Rev Microbiol (2006) 1.33
A new means of inducibly inactivating a cellular protein. Mol Cell Biol (1988) 1.30
A new generation of protein display scaffolds for molecular recognition. Protein Sci (2006) 1.29
Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein. J Virol (2007) 1.18
Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins. J Biol Chem (2005) 1.17
The nucleocapsid protein of the SARS coronavirus is capable of self-association through a C-terminal 209 amino acid interaction domain. Biochem Biophys Res Commun (2004) 1.16
Structure of the SARS coronavirus nucleocapsid protein RNA-binding dimerization domain suggests a mechanism for helical packaging of viral RNA. J Mol Biol (2007) 1.08
mRNA display selection of a high-affinity, modification-specific phospho-IkappaBalpha-binding fibronectin. ACS Chem Biol (2008) 1.07
Intrabodies as drug discovery tools and therapeutics. Curr Opin Chem Biol (2005) 1.04
Modular organization of SARS coronavirus nucleocapsid protein. J Biomed Sci (2005) 1.04
A peptide core motif for binding to heterotrimeric G protein alpha subunits. J Biol Chem (2005) 0.98
Design, expression, and stability of a diverse protein library based on the human fibronectin type III domain. Protein Sci (2007) 0.97
Isolation of intracellular proteinase inhibitors derived from designed ankyrin repeat proteins by genetic screening. J Biol Chem (2006) 0.95
Effects of intrabodies specific for rotavirus NSP5 during the virus replicative cycle. J Gen Virol (2004) 0.93
Recombinant severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein forms a dimer through its C-terminal domain. J Biol Chem (2005) 0.93
Carboxyl terminus of severe acute respiratory syndrome coronavirus nucleocapsid protein: self-association analysis and nucleic acid binding characterization. Biochemistry (2006) 0.92
The molecular biology of SARS coronavirus. Ann N Y Acad Sci (2007) 0.88
Intracellular stability of anti-caspase-3 intrabodies determines efficacy in retargeting the antigen. J Biol Chem (2001) 0.86
Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies. Eur J Biochem (2003) 0.82
Renilla luciferase as a reporter to assess SARS-CoV mRNA transcription regulation and efficacy of anti-SARS-CoV agents. Adv Exp Med Biol (2006) 0.81
Aggresome formation by anti-Ras intracellular scFv fragments. The fate of the antigen-antibody complex. Eur J Biochem (2001) 0.78
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity (2002) 6.85
A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. Cell (2006) 6.45
Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol (2013) 4.98
Mechanisms of GII.4 norovirus persistence in human populations. PLoS Med (2008) 4.57
Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. J Virol (2002) 4.29
Structure of the bacterial RNA polymerase promoter specificity sigma subunit. Mol Cell (2002) 4.22
RTP family members induce functional expression of mammalian odorant receptors. Cell (2004) 4.09
Norwalk virus: how infectious is it? J Med Virol (2008) 3.93
Polyproline II structure in a sequence of seven alanine residues. Proc Natl Acad Sci U S A (2002) 3.54
Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. Cell Host Microbe (2012) 3.32
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
The emergence of competition between model protocells. Science (2004) 3.10
Binding of Norwalk virus-like particles to ABH histo-blood group antigens is blocked by antisera from infected human volunteers or experimentally vaccinated mice. J Virol (2002) 2.98
Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2003) 2.82
Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission. J Virol (2009) 2.60
Cellular and humoral immunity following Snow Mountain virus challenge. J Virol (2005) 2.59
Viral shape-shifting: norovirus evasion of the human immune system. Nat Rev Microbiol (2010) 2.53
Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions. Proc Natl Acad Sci U S A (2012) 2.42
Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons. Neuron (2005) 2.29
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice. J Virol (2005) 2.22
Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm. Proc Natl Acad Sci U S A (2008) 2.22
Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane. J Virol (2007) 2.18
Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci U S A (2014) 2.17
NF-kappaB inhibits gammaherpesvirus lytic replication. J Virol (2003) 2.15
Fluorescent imaging of single nanoparticles and viruses on a smart phone. ACS Nano (2013) 2.14
Autophagy links inflammasomes to atherosclerotic progression. Cell Metab (2012) 2.08
Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. J Virol (2005) 2.05
Immunogenetic mechanisms driving norovirus GII.4 antigenic variation. PLoS Pathog (2012) 2.02
Identification of viral genes essential for replication of murine gamma-herpesvirus 68 using signature-tagged mutagenesis. Proc Natl Acad Sci U S A (2005) 1.98
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc Natl Acad Sci U S A (2008) 1.97
Transcription program of murine gammaherpesvirus 68. J Virol (2003) 1.96
Norovirus pathogenesis: mechanisms of persistence and immune evasion in human populations. Immunol Rev (2008) 1.96
A decade after SARS: strategies for controlling emerging coronaviruses. Nat Rev Microbiol (2013) 1.94
Heterologous gene expression from transmissible gastroenteritis virus replicon particles. J Virol (2002) 1.85
Characterization of interactions between RTA and the promoter of polyadenylated nuclear RNA in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J Virol (2002) 1.83
Recombinant probes for visualizing endogenous synaptic proteins in living neurons. Neuron (2013) 1.80
Norovirus capture with histo-blood group antigens reveals novel virus-ligand interactions. J Virol (2004) 1.80
Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling. MBio (2010) 1.79
Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. Proc Natl Acad Sci U S A (2005) 1.76
Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J Virol (2007) 1.75
Evidence supporting a zoonotic origin of human coronavirus strain NL63. J Virol (2012) 1.75
Identification of proteins associated with murine gammaherpesvirus 68 virions. J Virol (2003) 1.75
Multivalent norovirus vaccines induce strong mucosal and systemic blocking antibodies against multiple strains. Vaccine (2006) 1.74
Norovirus GII.4 strain antigenic variation. J Virol (2010) 1.73
Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus. Proc Natl Acad Sci U S A (2013) 1.73
The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication. J Virol (2005) 1.71
Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host Microbe (2007) 1.71
Heterotypic humoral and cellular immune responses following Norwalk virus infection. J Virol (2009) 1.70
Extension of Drosophila melanogaster life span with a GPCR peptide inhibitor. Nat Chem Biol (2007) 1.70
Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection. PLoS Pathog (2008) 1.69
Antibody is critical for the clearance of murine norovirus infection. J Virol (2008) 1.69
Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures. J Virol (2013) 1.68
Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing. PLoS Pathog (2010) 1.67
Three-dimensional visualization of gammaherpesvirus life cycle in host cells by electron tomography. Structure (2010) 1.65
Transcriptional regulation of the interleukin-6 gene of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus). J Virol (2002) 1.60
Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. J Virol (2009) 1.58
Natural strain variation and antibody neutralization of dengue serotype 3 viruses. PLoS Pathog (2010) 1.56
Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice. J Virol (2005) 1.54
Screening for osteoporosis in men: a systematic review for an American College of Physicians guideline. Ann Intern Med (2008) 1.53
Genetic mapping of a highly variable norovirus GII.4 blockade epitope: potential role in escape from human herd immunity. J Virol (2011) 1.53
Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. Dev Cell (2008) 1.53
Quantitative imaging of single, unstained viruses with coherent x rays. Phys Rev Lett (2008) 1.52
Herd immunity to GII.4 noroviruses is supported by outbreak patient sera. J Virol (2009) 1.51
Emergence of new pandemic GII.4 Sydney norovirus strain correlates with escape from herd immunity. J Infect Dis (2013) 1.47
MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. PLoS Pathog (2008) 1.47
A general approach to detect protein expression in vivo using fluorescent puromycin conjugates. Chem Biol (2004) 1.45
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
A novel strategy for in vitro selection of peptide-drug conjugates. Chem Biol (2003) 1.42
Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus. MBio (2013) 1.41
Cynomolgus macaque as an animal model for severe acute respiratory syndrome. PLoS Med (2006) 1.40
Norovirus immunity and the great escape. PLoS Pathog (2012) 1.40
Murine gammaherpesvirus 68 open reading frame 31 is required for viral replication. J Virol (2004) 1.40
Comparative study of regulation of RTA-responsive genes in Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8. J Virol (2003) 1.36
Emergence of a norovirus GII.4 strain correlates with changes in evolving blockade epitopes. J Virol (2012) 1.36
Persistent gammaherpesvirus replication and dynamic interaction with the host in vivo. J Virol (2008) 1.36
Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles. J Virol (2002) 1.36
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice. G3 (Bethesda) (2012) 1.35
MicroRNAs encoded by Kaposi's sarcoma-associated herpesvirus regulate viral life cycle. EMBO Rep (2010) 1.34
SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon. Curr Opin Virol (2012) 1.33
Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication. J Virol (2004) 1.32
Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF. Cell (2002) 1.32
Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus. PLoS Pathog (2007) 1.32
SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism. PLoS Pathog (2010) 1.32
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68. PLoS Pathog (2009) 1.31
Kaposi's sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-kappaB and JNK/AP1 pathways. Oncogene (2003) 1.31
Encodamers: unnatural peptide oligomers encoded in RNA. Chem Biol (2003) 1.30
Conserved herpesviral kinase promotes viral persistence by inhibiting the IRF-3-mediated type I interferon response. Cell Host Microbe (2009) 1.30
High-resolution functional profiling of hepatitis C virus genome. PLoS Pathog (2008) 1.30
Monoclonal antibody-based antigenic mapping of norovirus GII.4-2002. J Virol (2011) 1.29
mRNA display: ligand discovery, interaction analysis and beyond. Trends Biochem Sci (2003) 1.29
A distinct translation initiation mechanism generates cryptic peptides for immune surveillance. PLoS One (2008) 1.26