Published in J Biol Chem on July 05, 1990
Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure. Mol Cell Biol (1993) 6.36
A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J Cell Biol (1997) 4.93
Stationary phase in the yeast Saccharomyces cerevisiae. Microbiol Rev (1993) 4.54
Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins. Mol Cell Biol (1992) 4.04
Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1. J Bacteriol (1991) 2.47
Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol Cell Biol (1997) 2.40
An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity. Mol Cell Biol (1993) 2.20
Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1. Mol Cell Biol (1991) 1.92
Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol (1995) 1.88
Cloning and characterization of DST2, the gene for DNA strand transfer protein beta from Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.88
Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease. Mol Cell Biol (1995) 1.74
rar mutations which increase artificial chromosome stability in Saccharomyces cerevisiae identify transcription and recombination proteins. Nucleic Acids Res (1991) 1.50
Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein. Proc Natl Acad Sci U S A (1994) 1.43
A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. EMBO J (1995) 1.40
Telomere length regulation and telomeric chromatin require the nonsense-mediated mRNA decay pathway. Mol Cell Biol (1998) 1.35
The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics (1995) 1.30
Isolation, DNA sequence, and regulation of a Saccharomyces cerevisiae gene that encodes DNA strand transfer protein alpha. Mol Cell Biol (1991) 1.29
Mutations in VPS16 and MRT1 stabilize mRNAs by activating an inhibitor of the decapping enzyme. Mol Cell Biol (1999) 1.23
Roles of a Trypanosoma brucei 5'->3' exoribonuclease homolog in mRNA degradation. RNA (2006) 1.17
Single-stranded DNA binding protein and DNA helicase of bacteriophage T7 mediate homologous DNA strand exchange. EMBO J (1996) 1.16
Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol Cell Biol (1999) 1.08
Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation. Nucleic Acids Res (1995) 1.06
Characterization of two nuclear mammalian homologous DNA-pairing activities that do not require associated exonuclease activity. Proc Natl Acad Sci U S A (1995) 0.91
Purification and characterization of a DNA strand transferase from broccoli. Plant Physiol (1995) 0.75
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene (1988) 42.65
Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme. Proc Natl Acad Sci U S A (1977) 14.75
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains. Proc Natl Acad Sci U S A (1968) 6.82
Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Proc Natl Acad Sci U S A (1978) 6.33
Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity. Proc Natl Acad Sci U S A (1978) 5.33
Slow joining of newly replicated DNA chains in DNA polymerase I-deficient Escherichia coli mutants. Proc Natl Acad Sci U S A (1971) 4.87
Intraspecific nucleotide sequence variability surrounding the origin of replication in human mitochondrial DNA. Gene (1983) 4.47
A third essential DNA polymerase in S. cerevisiae. Cell (1990) 4.46
RNA-linked nascent DNA fragments in Escherichia coli. Proc Natl Acad Sci U S A (1972) 4.35
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc Natl Acad Sci U S A (1995) 3.59
Pathway correcting DNA replication errors in Saccharomyces cerevisiae. EMBO J (1993) 3.57
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity. Proc Natl Acad Sci U S A (1991) 3.44
A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Mol Cell Biol (1993) 3.33
Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis. Genes Dev (1997) 3.05
The product of the Saccharomyces cerevisiae cell cycle gene DBF2 has homology with protein kinases and is periodically expressed in the cell cycle. Mol Cell Biol (1990) 2.99
The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae. Mol Gen Genet (1994) 2.73
Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae. EMBO J (2001) 2.70
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus. J Virol (2000) 2.65
DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae. EMBO J (1992) 2.51
The cell-cycle-regulated budding yeast gene DBF2, encoding a putative protein kinase, has a homologue that is not under cell-cycle control. Gene (1991) 2.47
The intrinsic ATPase of DNA gyrase. J Biol Chem (1980) 2.41
Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol Cell Biol (2000) 2.35
Structure and activities of Escherichia coli DNA gyrase. Cold Spring Harb Symp Quant Biol (1979) 2.35
Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae. Nucleic Acids Res (1991) 2.34
Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication. Mol Cell Biol (1998) 2.25
Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes. Mol Cell Biol (1995) 2.21
Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem (2001) 2.15
Interaction of bacteriophage T4 RNA and DNA ligases in joining of duplex DNA at base-paired ends. J Biol Chem (1977) 2.13
Bacteriophage T4 RNA ligase. Reaction intermediates and interaction of substrates. J Biol Chem (1977) 2.07
Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme. J Biol Chem (1990) 2.06
Catalysis of DNA joining by bacteriophage T4 RNA ligase. Biochem Biophys Res Commun (1976) 1.91
Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast. Proc Natl Acad Sci U S A (1996) 1.89
Cloning and characterization of DST2, the gene for DNA strand transfer protein beta from Saccharomyces cerevisiae. Mol Cell Biol (1991) 1.88
DNA chain growth: in vivo and in vitro synthesis in a DNA polymerase-negative mutant of E. coli. Nature (1970) 1.79
Mechanism of DNA chain growth. Vii. Direction and rate of growth of T4 nascent short DNA chains. J Mol Biol (1972) 1.78
Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition. Genetics (1992) 1.76
DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1991) 1.75
DNA gyrase subunit stoichiometry and the covalent attachment of subunit A to DNA during DNA cleavage. Nucleic Acids Res (1980) 1.69
Bacillus subtilis deoxyribonucleic acid gyrase. J Bacteriol (1980) 1.62
Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.52
Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae. Genes Cells (2000) 1.36
Yeast 2-micrometer plasmid DNA replication in vitro: origin and direction. Proc Natl Acad Sci U S A (1981) 1.36
In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir. Antimicrob Agents Chemother (1998) 1.36
RNA-linked DNA fragments in vitro. Proc Natl Acad Sci U S A (1973) 1.34
Morphogenesis of phi X174: in vitro synthesis of infectious phage from purified viral components. Proc Natl Acad Sci U S A (1981) 1.34
DNA polymerases, deoxyribonucleases, and recombination during meiosis in Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.33
Yeast 2-microns plasmid DNA replication in vitro: purification of the CDC8 gene product by complementation assay. Proc Natl Acad Sci U S A (1983) 1.30
Isolation, DNA sequence, and regulation of a Saccharomyces cerevisiae gene that encodes DNA strand transfer protein alpha. Mol Cell Biol (1991) 1.29
In vitro replication of bacteriophage phi 29 DNA. Proc Natl Acad Sci U S A (1982) 1.29
DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts. Proc Natl Acad Sci U S A (2001) 1.28
Isolation and identification of bacteriophage phi X174 prohead. Proc Natl Acad Sci U S A (1979) 1.27
The RFC2 gene, encoding the third-largest subunit of the replication factor C complex, is required for an S-phase checkpoint in Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.27
Use of a cloned double stranded cDNA coding for a major androgen dependent protein in rat seminal vesicle secretion: the effect of testosterone in gene expression. Nucleic Acids Res (1981) 1.23
Characterization of the yeast Cdc7p/Dbf4p complex purified from insect cells. Its protein kinase activity is regulated by Rad53p. J Biol Chem (2000) 1.23
The yeast Saccharomyces cerevisiae DNA polymerase IV: possible involvement in double strand break DNA repair. Nucleic Acids Res (1994) 1.23
DNA polymerase alpha mutants from a Drosophila melanogaster cell line. Proc Natl Acad Sci U S A (1980) 1.16
The RFC2 gene encoding a subunit of replication factor C of Saccharomyces cerevisiae. Nucleic Acids Res (1994) 1.16
First the CDKs, now the DDKs. Trends Cell Biol (1999) 1.15
Modulation of mutation rates in bacteriophage T4 by a base-pair change a dozen nucleotides removed. J Mol Biol (1984) 1.15
Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae. Nucleic Acids Res (2000) 1.12
Isolation, DNA sequence and regulation of a new cell division cycle gene from the yeast Saccharomyces cerevisiae. Yeast (1990) 1.11
Purification and characterization of a new DNA polymerase from budding yeast Saccharomyces cerevisiae. A probable homolog of mammalian DNA polymerase beta. J Biol Chem (1993) 1.11
A cell-cycle-regulated trans-factor, DSC1, controls expression of DNA synthesis genes in yeast. Cold Spring Harb Symp Quant Biol (1991) 1.08
Presynapsis and synapsis of DNA promoted by the STP alpha and single-stranded DNA-binding proteins from Saccharomyces cerevisiae. J Biol Chem (1989) 1.07
A new DNA-dependent ATPase which stimulates yeast DNA polymerase I and has DNA-unwinding activity. J Biol Chem (1986) 1.05
In vitro synthesis of bacteriophage phi X174 by purified components. Proc Natl Acad Sci U S A (1983) 1.05
DNA polymerase II, the epsilon polymerase of Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol (1993) 1.04
The UL8 component of the herpes simplex virus helicase-primase complex stimulates primer synthesis by a subassembly of the UL5 and UL52 components. J Biol Chem (1994) 1.02
Nucleotide sequence of the POL3 gene encoding DNA polymerase III (delta) of Saccharomyces cerevisiae. Nucleic Acids Res (1992) 1.02
The second subunit of DNA polymerase III (delta) is encoded by the HYS2 gene in Saccharomyces cerevisiae. Nucleic Acids Res (1998) 1.00
A mutation in the rnh-locus of Escherichia coli affects the structural gene for RNase H. Examination of the mutant and wild type protein. J Biol Chem (1982) 0.99
Molecular analysis of the dhp1+ gene of Schizosaccharomyces pombe: an essential gene that has homology to the DST2 and RAT1 genes of Saccharomyces cerevisiae. Mol Gen Genet (1994) 0.99
Bacteriophage T4 RNA ligase: preparation of a physically homogeneous, nuclease-free enzyme from hyperproducing infected cells. Nucleic Acids Res (1977) 0.96
Deletions of the carboxy terminus of herpes simplex virus type 1 UL42 define a conserved amino-terminal functional domain. J Virol (1993) 0.96
Kinetic analysis of base substitution mutagenesis by transient misalignment of DNA and by miscoding. J Biol Chem (1989) 0.96
Yeast replicative DNA polymerases and their role at the replication fork. Mol Cells (2001) 0.94
Mapping and characterizing a new DNA replication mutant in Saccharomyces cerevisiae. Yeast (1989) 0.93
DNA polymerase II (epsilon) of Saccharomyces cerevisiae dissociates from the DNA template by sensing single-stranded DNA. J Biol Chem (1998) 0.91
Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1. Biochim Biophys Acta (2000) 0.90
Purification and characterization of DNA helicase III from the yeast Saccharomyces cerevisiae. J Biol Chem (1993) 0.89
Purification of a DNA primase activity from the yeast Saccharomyces cerevisiae. Primase can be separated from DNA polymerase I. J Biol Chem (1985) 0.88
A Cdc7p-Dbf4p protein kinase activity is conserved from yeast to humans. Prog Cell Cycle Res (2000) 0.87
The J gene of bacteriophage phi X174: in vitro analysis of J protein function. J Virol (1985) 0.86
Roles of POL3, POL2 and PMS1 genes in maintaining accurate DNA replication. Chromosoma (1992) 0.85
Novobiocin and nalidixic acid target proteins in yeast. Biochem Biophys Res Commun (1980) 0.85
Characterization of monoclonal antibodies recognizing amino- and carboxy-terminal epitopes of the herpes simplex virus UL42 protein. Virus Res (1995) 0.85
Role of DNA gyrase subunits in synthesis of bacteriophage phi X174 viral DNA. Proc Natl Acad Sci U S A (1981) 0.85
Purification and characterization of the coliphage N4-coded single-stranded DNA binding protein. J Biol Chem (1989) 0.85
The fidelity of DNA synthesis by the catalytic subunit of yeast DNA polymerase alpha alone and with accessory proteins. Mutat Res (1991) 0.83
Functional activity of oligosaccharide-deficient (Na,K)ATPase expressed in Xenopus oocytes. FEBS Lett (1988) 0.82
Cloning of the replication origin from Drosophila virilis mitochondrial DNA. Biochem Biophys Res Commun (1979) 0.81
Synthesis of bioactive PMMA bone cement via modification with methacryloxypropyltri-methoxysilane and calcium acetate. J Mater Sci Mater Med (2005) 0.78
Sequence-dependent primer synthesis by the herpes simplex virus helicase-primase complex. J Biol Chem (1995) 0.77
Purification of phi X174 gene C protein. J Biol Chem (1983) 0.77