Published in Cancer Res on July 15, 1990
Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene. J Exp Med (1992) 1.21
Research and development of next generation of antibody-based therapeutics. Acta Pharmacol Sin (2010) 1.15
Bispecific anti-human red blood Rhesus-D antigen x anti Fc gamma RI targeted antibody-dependent cell-mediated cytotoxicity and phagocytosis by mononuclear leucocytes. Clin Exp Immunol (1992) 0.79
Strategies in antibody therapy of cancer. Clin Exp Immunol (1990) 0.76
Generation of chimeric bispecific G250/anti-CD3 monoclonal antibody, a tool to combat renal cell carcinoma. Br J Cancer (1996) 0.75
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med (1998) 11.03
AINTEGUMENTA, an APETALA2-like gene of Arabidopsis with pleiotropic roles in ovule development and floral organ growth. Plant Cell (1996) 5.09
Identification of macrophage-like characteristics in a cultured murine tumor line. J Immunol (1975) 4.10
The three-dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site. Proc Natl Acad Sci U S A (1974) 3.92
Regulation of Toll-like receptors in human monocytes and dendritic cells. J Immunol (2001) 3.45
The fine specificity of antigen and Ia determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c. Cell (1982) 3.38
Quantitative in vitro assay of cytotoxic cellular immunity. J Natl Cancer Inst (1970) 3.12
Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation. Proc Natl Acad Sci U S A (1977) 3.07
Binding of affinity cross-linked oligomers of IgG to cells bearing Fc receptors. J Immunol (1977) 2.74
Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J Immunol (1996) 2.24
Immunization of patients with melanoma peptide vaccines: immunologic assessment using the ELISPOT assay. Cancer J Sci Am (1998) 2.14
T-cell clones from melanoma patients immunized against an anchor-modified gp100 peptide display discordant effector phenotypes. Cancer J (2001) 2.08
Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals. Environ Health Perspect (1999) 2.03
Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody. Nature (1985) 2.00
Three-dimensional structure of immunoglobulins. Annu Rev Biochem (1975) 1.99
Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4. Proc Natl Acad Sci U S A (2001) 1.96
Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies. J Virol (1996) 1.85
Texas Red, a hydrophilic, red-emitting fluorophore for use with fluorescein in dual parameter flow microfluorometric and fluorescence microscopic studies. J Immunol Methods (1982) 1.80
The interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. I. Analysis of the mechanism of binding. J Immunol (1984) 1.77
Isolation and characterization of Schizosaccharomyces pombe mutants defective in cell wall (1-3)beta-D-glucan. J Bacteriol (1991) 1.72
Impact of cytokine administration on the generation of antitumor reactivity in patients with metastatic melanoma receiving a peptide vaccine. J Immunol (1999) 1.71
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses. J Immunol (2000) 1.68
Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes. J Immunol (2000) 1.68
Nutrient effects on anthracycline production by Streptomyces peucetius in a defined medium. Can J Microbiol (1985) 1.62
The relationship between immune interferon production and proliferation in antigen-specific, MHC-restricted T cell lines and clones. J Immunol (1983) 1.61
Structure at 4.5 A resolution of a phosphorylcholine-binding fab. Nat New Biol (1973) 1.60
Mechanism of binding of multivalent immune complexes to Fc receptors. 1. Equilibrium binding. Biochemistry (1981) 1.56
Enhanced immunogenicity of chemically-coated syngeneic tumor cells. Proc Natl Acad Sci U S A (1971) 1.55
Lymphocyte cytotoxicity reactions to leukemia-associated antigens in identical twins. Int J Cancer (1972) 1.55
Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor. J Neurosci (2001) 1.53
The subclass specificity for the binding of murine myeloma proteins to macrophage and lymphocyte cell lines and to normal spleen cells. J Immunol (1978) 1.48
Quantitative assessment of cellular and humoral responses to skin and tumor allografts. Transplantation (1971) 1.48
Reducing tidal volume and increasing positive end-expiratory pressure with constant plateau pressure during one-lung ventilation: effect on oxygenation. Br J Anaesth (2012) 1.44
Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J Clin Invest (2001) 1.43
Qualitative and quantitative studies of cytotoxic immune cells. J Immunol (1971) 1.42
Investigator-initiated trials of targeted oncology agents: why independent research is at risk? Ann Oncol (2010) 1.41
Localisation of the Schizosaccharomyces pombe rho1p GTPase and its involvement in the organisation of the actin cytoskeleton. J Cell Sci (1997) 1.39
Fc (IgG) receptors on rat basophilic leukemia cells. J Immunol (1981) 1.39
Critical illness-related corticosteroid insufficiency in cardiogenic shock. Br J Anaesth (2013) 1.38
Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma. J Immunother (2000) 1.37
Effect of vesicular stomatitis virus infection on the histocompatibility antigen of L cells. J Virol (1972) 1.36
The Schizosaccharomyces pombe cwg2+ gene codes for the beta subunit of a geranylgeranyltransferase type I required for beta-glucan synthesis. EMBO J (1993) 1.35
Interactions of vesicular stomatitis virus with murine cell surface antigens. J Virol (1976) 1.35
Crystals of phosphorylcholine-binding Fab-fragments from mouse myeloma proteins: preparation and x-ray analysis. Proc Natl Acad Sci U S A (1972) 1.34
The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor. J Biol Chem (2001) 1.25
Independent evolution of HIV type 1 in different brain regions. AIDS Res Hum Retroviruses (1999) 1.25
Human K/natural killer cells targeted with hetero-cross-linked antibodies specifically lyse tumor cells in vitro and prevent tumor growth in vivo. J Immunol (1987) 1.25
Constitutive expression of Bc1-3 in thymocytes increases the DNA binding of NF-kappaB1 (p50) homodimers in vivo. Mol Cell Biol (1996) 1.24
Filipin as a flow microfluorometry probe for cellular cholesterol. Cytometry (1984) 1.23
Dimers and trimers of immunoglobulin G covalently cross-linked with a bivalent affinity label. Biochemistry (1976) 1.23
Human leukocyte Fc (IgG) receptors: quantitation and affinity with radiolabeled affinity cross-linked rabbit IgG. J Immunol (1979) 1.21
Production of target-specific effector cells using hetero-cross-linked aggregates containing anti-target cell and anti-Fc gamma receptor antibodies. J Exp Med (1984) 1.19
Schizosaccharomyces pombe protein kinase C homologues, pck1p and pck2p, are targets of rho1p and rho2p and differentially regulate cell integrity. J Cell Sci (1999) 1.18
Multiple dimeric forms of human CD69 result from differential addition of N-glycans to typical (Asn-X-Ser/Thr) and atypical (Asn-X-cys) glycosylation motifs. J Biol Chem (1997) 1.16
Effects of pH, temperature, and Eh on the uptake of cadmium by bacteria and an artificial sediment. Bull Environ Contam Toxicol (1982) 1.15
Association between entero-hepatic Helicobacter species and Crohn's disease: a prospective cross-sectional study. Aliment Pharmacol Ther (2009) 1.15
Suppressor cells in tumor-bearing mice capable of nonspecific blocking of in vitro immunization against transplant antigens. J Immunol (1975) 1.15
Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors. Biochemistry (1971) 1.14
Structure, genomic organization, and expression of the Arabidopsis thaliana aconitase gene. Plant aconitase show significant homology with mammalian iron-responsive element-binding protein. J Biol Chem (1995) 1.12
Mechanism of binding of multivalent immune complexes to Fc receptors. 2. Kinetics of binding. Biochemistry (1981) 1.12
TrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptor. Mol Cell Biol (2000) 1.10
Production and characterization of a monoclonal antibody that binds Reed-Sternberg cells. J Immunol (1985) 1.10
Specific targeting of human peripheral blood T cells by heteroaggregates containing anti-T3 crosslinked to anti-target cell antibodies. J Exp Med (1986) 1.09
Targeted adenovirus-mediated gene delivery to T cells via CD3. J Virol (1997) 1.09
Targeted antigen presentation using crosslinked antibody heteroaggregates. J Immunol (1987) 1.09
Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer. Hum Gene Ther (2000) 1.09
The ontogeny and distribution of B cells in normal and mutant immune-defective CBA/N mice: two-parameter analysis of surface IgM and IgD. J Immunol (1983) 1.07
Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis. Oncogene (1999) 1.07
p75 Co-receptors regulate ligand-dependent and ligand-independent Trk receptor activation, in part by altering Trk docking subdomains. J Biol Chem (2001) 1.07
Vascular hyporesponsiveness to vasopressors in septic shock: from bench to bedside. Intensive Care Med (2010) 1.06
Schizosaccharomyces pombe rho2p GTPase regulates cell wall alpha-glucan biosynthesis through the protein kinase pck2p. Mol Biol Cell (2000) 1.05
Differential sorting of human parathyroid hormone after transduction of mouse and rat salivary glands. Hum Gene Ther (2008) 1.04
The fate of IgE bound to rat basophilic leukemia cells. II. Endocytosis of IgE oligomers and effect on receptor turnover. J Immunol (1983) 1.04
CD38 triggers cytotoxic responses in activated human natural killer cells. Blood (1999) 1.02
Targeted cytotoxic cells in human peripheral blood lymphocytes. J Immunol (1990) 1.02
Effects of improvements of poorly fitting dentures and new dentures on patient satisfaction. J Prosthet Dent (1996) 1.02
Changes in glutathione status and the antioxidant system in blood and in cancer cells associate with tumour growth in vivo. Free Radic Biol Med (1999) 1.02
Quantitation of Fc receptors and surface immunoglobulin is affected by cell isolation procedures using plasmagel and ficoll-hypaque. J Immunol Methods (1978) 1.02
Temporary inhibition of antibody-dependent, cell-mediated cytotoxicity by pretreatment of human attacking cells with ammonium chloride. J Immunol (1976) 1.01
Stable model immune complexes produced by bivalent affinity labeling haptens: in-vivo survival. Mol Immunol (1979) 1.00
Composition and mass of peptides released during tryptic and chymotryptic hydrolysis of myosin. J Biol Chem (1967) 0.99