Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
|
Nat Med
|
2006
|
24.38
|
2
|
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.
|
J Exp Med
|
2004
|
13.55
|
3
|
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection.
|
Nature
|
2005
|
13.15
|
4
|
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation.
|
J Immunol Methods
|
2003
|
11.81
|
5
|
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.
|
Nat Med
|
2009
|
8.45
|
6
|
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection.
|
J Exp Med
|
2006
|
8.18
|
7
|
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome.
|
Nature
|
2008
|
8.17
|
8
|
A human memory T cell subset with stem cell-like properties.
|
Nat Med
|
2011
|
7.47
|
9
|
Plasma levels of soluble CD14 independently predict mortality in HIV infection.
|
J Infect Dis
|
2011
|
7.41
|
10
|
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.
|
Blood
|
2002
|
6.73
|
11
|
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection.
|
J Infect Dis
|
2009
|
6.17
|
12
|
Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses.
|
J Exp Med
|
2007
|
5.22
|
13
|
HIV disease: fallout from a mucosal catastrophe?
|
Nat Immunol
|
2006
|
5.08
|
14
|
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist.
|
N Engl J Med
|
2009
|
4.97
|
15
|
Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans.
|
Nat Med
|
2012
|
4.74
|
16
|
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections.
|
Blood
|
2008
|
4.34
|
17
|
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
|
Sci Transl Med
|
2010
|
4.07
|
18
|
T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis.
|
J Virol
|
2004
|
4.02
|
19
|
Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo.
|
Nat Immunol
|
2002
|
4.00
|
20
|
Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.
|
Nat Med
|
2010
|
3.81
|
21
|
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.
|
J Immunol
|
2007
|
3.71
|
22
|
T cell receptor recognition motifs govern immune escape patterns in acute SIV infection.
|
Immunity
|
2004
|
3.69
|
23
|
Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses.
|
J Exp Med
|
2005
|
3.63
|
24
|
PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors.
|
J Clin Invest
|
2014
|
3.54
|
25
|
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
|
J Exp Med
|
2007
|
3.45
|
26
|
The molecular basis for public T-cell responses?
|
Nat Rev Immunol
|
2008
|
3.32
|
27
|
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
|
PLoS Pathog
|
2010
|
3.28
|
28
|
Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation.
|
J Exp Med
|
2006
|
3.26
|
29
|
Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.
|
J Immunol
|
2007
|
3.24
|
30
|
CD8+ T cell efficacy in vaccination and disease.
|
Nat Med
|
2008
|
3.20
|
31
|
Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations.
|
Eur J Immunol
|
2007
|
3.18
|
32
|
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells.
|
Nat Med
|
2005
|
3.01
|
33
|
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues.
|
Proc Natl Acad Sci U S A
|
2014
|
2.95
|
34
|
SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.
|
Blood
|
2007
|
2.95
|
35
|
Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation.
|
Blood
|
2009
|
2.92
|
36
|
Collagen deposition limits immune reconstitution in the gut.
|
J Infect Dis
|
2008
|
2.85
|
37
|
Microbial translocation in HIV infection: causes, consequences and treatment opportunities.
|
Nat Rev Microbiol
|
2012
|
2.84
|
38
|
Second messenger role for Mg2+ revealed by human T-cell immunodeficiency.
|
Nature
|
2011
|
2.82
|
39
|
Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge.
|
J Exp Med
|
2006
|
2.60
|
40
|
CD4 T follicular helper cell dynamics during SIV infection.
|
J Clin Invest
|
2012
|
2.55
|
41
|
Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells.
|
J Virol
|
2002
|
2.44
|
42
|
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts.
|
Nat Med
|
2009
|
2.41
|
43
|
Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection.
|
Gastroenterology
|
2011
|
2.39
|
44
|
Systemic effects of inflammation on health during chronic HIV infection.
|
Immunity
|
2013
|
2.34
|
45
|
Characteristics of congenital hepatic fibrosis in a large cohort of patients with autosomal recessive polycystic kidney disease.
|
Gastroenterology
|
2012
|
2.33
|
46
|
Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity.
|
Blood
|
2009
|
2.33
|
47
|
IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates.
|
Blood
|
2002
|
2.31
|
48
|
Microbial translocation across the GI tract.
|
Annu Rev Immunol
|
2012
|
2.30
|
49
|
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients.
|
J Exp Med
|
2005
|
2.30
|
50
|
A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing.
|
J Immunol
|
2011
|
2.20
|
51
|
A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory.
|
Immunity
|
2011
|
2.15
|
52
|
Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity.
|
Sci Transl Med
|
2011
|
2.14
|
53
|
Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation.
|
Blood
|
2003
|
2.14
|
54
|
Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.
|
Proc Natl Acad Sci U S A
|
2005
|
2.10
|
55
|
Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.
|
N Engl J Med
|
2012
|
2.08
|
56
|
TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection.
|
Nat Immunol
|
2012
|
2.04
|
57
|
Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates.
|
Proc Natl Acad Sci U S A
|
2006
|
2.03
|
58
|
Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection.
|
J Exp Med
|
2009
|
2.03
|
59
|
The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration.
|
J Immunol
|
2004
|
2.01
|
60
|
Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner.
|
Blood
|
2004
|
2.01
|
61
|
T cell cross-reactivity and conformational changes during TCR engagement.
|
J Exp Med
|
2004
|
1.99
|
62
|
Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.
|
J Immunol
|
2006
|
1.98
|
63
|
Where does HIV live?
|
N Engl J Med
|
2004
|
1.96
|
64
|
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.
|
J Biol Chem
|
2005
|
1.92
|
65
|
Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion.
|
J Immunol
|
2008
|
1.82
|
66
|
The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.
|
Proc Natl Acad Sci U S A
|
2013
|
1.80
|
67
|
Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection.
|
Clin Vaccine Immunol
|
2006
|
1.80
|
68
|
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.
|
J Virol
|
2010
|
1.79
|
69
|
Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination.
|
Immunol Cell Biol
|
2011
|
1.78
|
70
|
A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis.
|
J Clin Invest
|
2011
|
1.75
|
71
|
TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV.
|
J Immunol
|
2008
|
1.70
|
72
|
Immune activation and HIV persistence: implications for curative approaches to HIV infection.
|
Immunol Rev
|
2013
|
1.68
|
73
|
Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo.
|
J Virol
|
2006
|
1.68
|
74
|
High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay.
|
Blood
|
2004
|
1.62
|
75
|
Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque.
|
J Clin Invest
|
2011
|
1.61
|
76
|
Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia.
|
Blood
|
2007
|
1.61
|
77
|
The mucosal barrier and immune activation in HIV pathogenesis.
|
Curr Opin HIV AIDS
|
2008
|
1.54
|
78
|
Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection.
|
J Immunol
|
2009
|
1.52
|
79
|
Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection.
|
Blood
|
2011
|
1.52
|
80
|
Nonprogressive and progressive primate immunodeficiency lentivirus infections.
|
Immunity
|
2010
|
1.50
|
81
|
Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.
|
J Immunol
|
2013
|
1.50
|
82
|
Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire.
|
Proc Natl Acad Sci U S A
|
2010
|
1.50
|
83
|
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.
|
J Immunol
|
2009
|
1.49
|
84
|
Hypomorphic Rag mutations can cause destructive midline granulomatous disease.
|
Blood
|
2010
|
1.47
|
85
|
Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo.
|
J Virol
|
2007
|
1.45
|
86
|
High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control.
|
J Virol
|
2011
|
1.44
|
87
|
Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination.
|
Proc Natl Acad Sci U S A
|
2006
|
1.43
|
88
|
T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization.
|
Clin Cancer Res
|
2005
|
1.43
|
89
|
Changes in JC virus-specific T cell responses during natalizumab treatment and in natalizumab-associated progressive multifocal leukoencephalopathy.
|
PLoS Pathog
|
2012
|
1.42
|
90
|
A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells.
|
Immunity
|
2013
|
1.41
|
91
|
Escape from highly effective public CD8+ T-cell clonotypes by HIV.
|
Blood
|
2011
|
1.39
|
92
|
Effects of exogenous interleukin-7 on human thymus function.
|
Blood
|
2002
|
1.38
|
93
|
Evidence for translocation of microbial products in patients with idiopathic CD4 lymphocytopenia.
|
J Infect Dis
|
2009
|
1.38
|
94
|
Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection.
|
J Immunol
|
2006
|
1.36
|
95
|
Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis.
|
J Clin Invest
|
2002
|
1.36
|
96
|
Reduction of immune activation with chloroquine therapy during chronic HIV infection.
|
J Virol
|
2010
|
1.32
|
97
|
CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection.
|
J Immunol
|
2008
|
1.31
|
98
|
Unbiased molecular analysis of T cell receptor expression using template-switch anchored RT-PCR.
|
Curr Protoc Immunol
|
2011
|
1.30
|
99
|
Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans.
|
Proc Natl Acad Sci U S A
|
2005
|
1.30
|
100
|
Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition.
|
J Biol Chem
|
2004
|
1.29
|
101
|
Factors influencing T-lymphopoiesis after allogeneic hematopoietic cell transplantation.
|
Transplantation
|
2002
|
1.27
|
102
|
Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.
|
Eur J Immunol
|
2010
|
1.27
|
103
|
High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow.
|
Blood
|
2008
|
1.26
|
104
|
Autocrine production of beta-chemokines protects CMV-Specific CD4 T cells from HIV infection.
|
PLoS Pathog
|
2009
|
1.24
|
105
|
Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells.
|
J Virol
|
2008
|
1.20
|
106
|
Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques.
|
J Immunol
|
2007
|
1.18
|
107
|
Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques.
|
Blood
|
2007
|
1.17
|
108
|
A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults.
|
BMJ Open
|
2011
|
1.15
|
109
|
Direct ex vivo analysis of human CD4(+) memory T cell activation requirements at the single clonotype level.
|
J Immunol
|
2002
|
1.15
|
110
|
Vaccine design for CD8 T lymphocyte responses.
|
Cold Spring Harb Perspect Med
|
2011
|
1.14
|
111
|
Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy.
|
AIDS
|
2013
|
1.14
|
112
|
Determinants of protection among HIV‐exposed seronegative persons: an overview.
|
J Infect Dis
|
2010
|
1.13
|
113
|
HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters.
|
J Immunol
|
2004
|
1.11
|
114
|
The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor.
|
Blood
|
2009
|
1.11
|
115
|
Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques.
|
J Immunol
|
2008
|
1.10
|
116
|
The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors.
|
Nat Rev Immunol
|
2010
|
1.10
|
117
|
Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies.
|
J Virol
|
2003
|
1.10
|
118
|
T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy.
|
Blood
|
2010
|
1.09
|
119
|
IFN-gamma mediates the death of Th1 cells in a paracrine manner.
|
J Immunol
|
2008
|
1.09
|
120
|
NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination.
|
Immunobiology
|
2012
|
1.09
|
121
|
Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response.
|
J Immunol
|
2010
|
1.08
|
122
|
Degeneracy and repertoire of the human HIV-1 Gag p17(77-85) CTL response.
|
J Immunol
|
2006
|
1.08
|
123
|
The clonal composition of human CD4+CD25+Foxp3+ cells determined by a comprehensive DNA-based multiplex PCR for TCRB gene rearrangements.
|
J Immunol Methods
|
2007
|
1.08
|
124
|
Renewing the T cell repertoire to arrest autoimmune aggression.
|
Trends Immunol
|
2006
|
1.07
|
125
|
Recombinatorial biases and convergent recombination determine interindividual TCRβ sharing in murine thymocytes.
|
J Immunol
|
2012
|
1.04
|
126
|
Longitudinal assessment of de novo T cell production in relation to HIV-associated T cell homeostasis failure.
|
AIDS Res Hum Retroviruses
|
2006
|
1.03
|
127
|
Identification and monitoring of graft-versus-host specific T-cell clone in stem cell transplantation.
|
Lancet
|
2003
|
1.03
|
128
|
T cell responses to whole SARS coronavirus in humans.
|
J Immunol
|
2008
|
1.03
|
129
|
Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers.
|
J Immunol Methods
|
2008
|
1.03
|
130
|
Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope.
|
J Immunol
|
2007
|
1.01
|
131
|
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection.
|
J Infect Dis
|
2014
|
1.00
|
132
|
Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints.
|
Retrovirology
|
2011
|
1.00
|
133
|
The role of production frequency in the sharing of simian immunodeficiency virus-specific CD8+ TCRs between macaques.
|
J Immunol
|
2008
|
0.99
|
134
|
Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells.
|
J Immunol
|
2011
|
0.98
|
135
|
CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.
|
J Immunol
|
2010
|
0.98
|
136
|
HLA class II polymorphisms determine responses to bacterial superantigens.
|
J Immunol
|
2004
|
0.98
|
137
|
Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation.
|
J Immunol
|
2011
|
0.98
|
138
|
Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections.
|
Curr Opin HIV AIDS
|
2010
|
0.98
|
139
|
HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells.
|
J Virol
|
2012
|
0.97
|
140
|
Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individuals.
|
Int Immunol
|
2005
|
0.97
|
141
|
Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection.
|
J Virol
|
2012
|
0.97
|
142
|
In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins.
|
Clin Cancer Res
|
2005
|
0.96
|
143
|
Alloreactive T cell clonotype recruitment in a mixed lymphocyte reaction: implications for graft engineering.
|
Exp Hematol
|
2006
|
0.95
|
144
|
Identification and in vitro expansion of CD4+ and CD8+ T cells specific for human neutrophil elastase.
|
Blood
|
2003
|
0.95
|
145
|
Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge.
|
J Med Primatol
|
2006
|
0.94
|
146
|
Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression.
|
J Immunol Methods
|
2011
|
0.93
|
147
|
Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity.
|
J Immunol
|
2009
|
0.92
|
148
|
Maintenance of naïve CD8 T cells in nonagenarians by leptin, IGFBP3 and T3.
|
Mech Ageing Dev
|
2009
|
0.92
|
149
|
Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus.
|
J Virol
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2002
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