Daniel C Douek

Author PubWeight™ 401.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006 24.38
2 CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004 13.55
3 Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005 13.15
4 Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 2003 11.81
5 HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nat Med 2009 8.45
6 PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med 2006 8.18
7 Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 2008 8.17
8 A human memory T cell subset with stem cell-like properties. Nat Med 2011 7.47
9 Plasma levels of soluble CD14 independently predict mortality in HIV infection. J Infect Dis 2011 7.41
10 Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood 2002 6.73
11 Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J Infect Dis 2009 6.17
12 Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses. J Exp Med 2007 5.22
13 HIV disease: fallout from a mucosal catastrophe? Nat Immunol 2006 5.08
14 An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 2009 4.97
15 Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. Nat Med 2012 4.74
16 Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 2008 4.34
17 Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med 2010 4.07
18 T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: implications for HIV pathogenesis. J Virol 2004 4.02
19 Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo. Nat Immunol 2002 4.00
20 Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. Nat Med 2010 3.81
21 Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys. J Immunol 2007 3.71
22 T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 2004 3.69
23 Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses. J Exp Med 2005 3.63
24 PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors. J Clin Invest 2014 3.54
25 Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection. J Exp Med 2007 3.45
26 The molecular basis for public T-cell responses? Nat Rev Immunol 2008 3.32
27 Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. PLoS Pathog 2010 3.28
28 Acquisition of direct antiviral effector functions by CMV-specific CD4+ T lymphocytes with cellular maturation. J Exp Med 2006 3.26
29 Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence. J Immunol 2007 3.24
30 CD8+ T cell efficacy in vaccination and disease. Nat Med 2008 3.20
31 Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations. Eur J Immunol 2007 3.18
32 Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells. Nat Med 2005 3.01
33 Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc Natl Acad Sci U S A 2014 2.95
34 SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection. Blood 2007 2.95
35 Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood 2009 2.92
36 Collagen deposition limits immune reconstitution in the gut. J Infect Dis 2008 2.85
37 Microbial translocation in HIV infection: causes, consequences and treatment opportunities. Nat Rev Microbiol 2012 2.84
38 Second messenger role for Mg2+ revealed by human T-cell immunodeficiency. Nature 2011 2.82
39 Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge. J Exp Med 2006 2.60
40 CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest 2012 2.55
41 Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells. J Virol 2002 2.44
42 Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat Med 2009 2.41
43 Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection. Gastroenterology 2011 2.39
44 Systemic effects of inflammation on health during chronic HIV infection. Immunity 2013 2.34
45 Characteristics of congenital hepatic fibrosis in a large cohort of patients with autosomal recessive polycystic kidney disease. Gastroenterology 2012 2.33
46 Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood 2009 2.33
47 IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates. Blood 2002 2.31
48 Microbial translocation across the GI tract. Annu Rev Immunol 2012 2.30
49 Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients. J Exp Med 2005 2.30
50 A mechanism for TCR sharing between T cell subsets and individuals revealed by pyrosequencing. J Immunol 2011 2.20
51 A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory. Immunity 2011 2.15
52 Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity. Sci Transl Med 2011 2.14
53 Functional leukemia-associated antigen-specific memory CD8+ T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. Blood 2003 2.14
54 Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. Proc Natl Acad Sci U S A 2005 2.10
55 Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions. N Engl J Med 2012 2.08
56 TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection. Nat Immunol 2012 2.04
57 Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates. Proc Natl Acad Sci U S A 2006 2.03
58 Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection. J Exp Med 2009 2.03
59 The functional profile of primary human antiviral CD8+ T cell effector activity is dictated by cognate peptide concentration. J Immunol 2004 2.01
60 Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. Blood 2004 2.01
61 T cell cross-reactivity and conformational changes during TCR engagement. J Exp Med 2004 1.99
62 Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. J Immunol 2006 1.98
63 Where does HIV live? N Engl J Med 2004 1.96
64 Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface. J Biol Chem 2005 1.92
65 Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion. J Immunol 2008 1.82
66 The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time. Proc Natl Acad Sci U S A 2013 1.80
67 Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection. Clin Vaccine Immunol 2006 1.80
68 Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques. J Virol 2010 1.79
69 Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination. Immunol Cell Biol 2011 1.78
70 A high-throughput single-cell analysis of human CD8⁺ T cell functions reveals discordance for cytokine secretion and cytolysis. J Clin Invest 2011 1.75
71 TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV. J Immunol 2008 1.70
72 Immune activation and HIV persistence: implications for curative approaches to HIV infection. Immunol Rev 2013 1.68
73 Preferential infection shortens the life span of human immunodeficiency virus-specific CD4+ T cells in vivo. J Virol 2006 1.68
74 High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay. Blood 2004 1.62
75 Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque. J Clin Invest 2011 1.61
76 Graft-versus-leukemia effects associated with detectable Wilms tumor-1 specific T lymphocytes after allogeneic stem-cell transplantation for acute lymphoblastic leukemia. Blood 2007 1.61
77 The mucosal barrier and immune activation in HIV pathogenesis. Curr Opin HIV AIDS 2008 1.54
78 Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection. J Immunol 2009 1.52
79 Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection. Blood 2011 1.52
80 Nonprogressive and progressive primate immunodeficiency lentivirus infections. Immunity 2010 1.50
81 Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression. J Immunol 2013 1.50
82 Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire. Proc Natl Acad Sci U S A 2010 1.50
83 Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point. J Immunol 2009 1.49
84 Hypomorphic Rag mutations can cause destructive midline granulomatous disease. Blood 2010 1.47
85 Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo. J Virol 2007 1.45
86 High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control. J Virol 2011 1.44
87 Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination. Proc Natl Acad Sci U S A 2006 1.43
88 T-cell responses directed against multiple HLA-A*0201-restricted epitopes derived from Wilms' tumor 1 protein in patients with leukemia and healthy donors: identification, quantification, and characterization. Clin Cancer Res 2005 1.43
89 Changes in JC virus-specific T cell responses during natalizumab treatment and in natalizumab-associated progressive multifocal leukoencephalopathy. PLoS Pathog 2012 1.42
90 A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells. Immunity 2013 1.41
91 Escape from highly effective public CD8+ T-cell clonotypes by HIV. Blood 2011 1.39
92 Effects of exogenous interleukin-7 on human thymus function. Blood 2002 1.38
93 Evidence for translocation of microbial products in patients with idiopathic CD4 lymphocytopenia. J Infect Dis 2009 1.38
94 Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection. J Immunol 2006 1.36
95 Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis. J Clin Invest 2002 1.36
96 Reduction of immune activation with chloroquine therapy during chronic HIV infection. J Virol 2010 1.32
97 CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection. J Immunol 2008 1.31
98 Unbiased molecular analysis of T cell receptor expression using template-switch anchored RT-PCR. Curr Protoc Immunol 2011 1.30
99 Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans. Proc Natl Acad Sci U S A 2005 1.30
100 Design of soluble recombinant T cell receptors for antigen targeting and T cell inhibition. J Biol Chem 2004 1.29
101 Factors influencing T-lymphopoiesis after allogeneic hematopoietic cell transplantation. Transplantation 2002 1.27
102 Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques. Eur J Immunol 2010 1.27
103 High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow. Blood 2008 1.26
104 Autocrine production of beta-chemokines protects CMV-Specific CD4 T cells from HIV infection. PLoS Pathog 2009 1.24
105 Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells. J Virol 2008 1.20
106 Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques. J Immunol 2007 1.18
107 Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaques. Blood 2007 1.17
108 A Phase I study evaluating the safety and immunogenicity of MVA85A, a candidate TB vaccine, in HIV-infected adults. BMJ Open 2011 1.15
109 Direct ex vivo analysis of human CD4(+) memory T cell activation requirements at the single clonotype level. J Immunol 2002 1.15
110 Vaccine design for CD8 T lymphocyte responses. Cold Spring Harb Perspect Med 2011 1.14
111 Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy. AIDS 2013 1.14
112 Determinants of protection among HIV‐exposed seronegative persons: an overview. J Infect Dis 2010 1.13
113 HIV-infected Langerhans cells preferentially transmit virus to proliferating autologous CD4+ memory T cells located within Langerhans cell-T cell clusters. J Immunol 2004 1.11
114 The transfer of adaptive immunity to CMV during hematopoietic stem cell transplantation is dependent on the specificity and phenotype of CMV-specific T cells in the donor. Blood 2009 1.11
115 Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques. J Immunol 2008 1.10
116 The quest for a T cell-based immune correlate of protection against HIV: a story of trials and errors. Nat Rev Immunol 2010 1.10
117 Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies. J Virol 2003 1.10
118 T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy. Blood 2010 1.09
119 IFN-gamma mediates the death of Th1 cells in a paracrine manner. J Immunol 2008 1.09
120 NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination. Immunobiology 2012 1.09
121 Persistent survival of prevalent clonotypes within an immunodominant HIV gag-specific CD8+ T cell response. J Immunol 2010 1.08
122 Degeneracy and repertoire of the human HIV-1 Gag p17(77-85) CTL response. J Immunol 2006 1.08
123 The clonal composition of human CD4+CD25+Foxp3+ cells determined by a comprehensive DNA-based multiplex PCR for TCRB gene rearrangements. J Immunol Methods 2007 1.08
124 Renewing the T cell repertoire to arrest autoimmune aggression. Trends Immunol 2006 1.07
125 Recombinatorial biases and convergent recombination determine interindividual TCRβ sharing in murine thymocytes. J Immunol 2012 1.04
126 Longitudinal assessment of de novo T cell production in relation to HIV-associated T cell homeostasis failure. AIDS Res Hum Retroviruses 2006 1.03
127 Identification and monitoring of graft-versus-host specific T-cell clone in stem cell transplantation. Lancet 2003 1.03
128 T cell responses to whole SARS coronavirus in humans. J Immunol 2008 1.03
129 Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers. J Immunol Methods 2008 1.03
130 Availability of a diversely avid CD8+ T cell repertoire specific for the subdominant HLA-A2-restricted HIV-1 Gag p2419-27 epitope. J Immunol 2007 1.01
131 Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection. J Infect Dis 2014 1.00
132 Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints. Retrovirology 2011 1.00
133 The role of production frequency in the sharing of simian immunodeficiency virus-specific CD8+ TCRs between macaques. J Immunol 2008 0.99
134 Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells. J Immunol 2011 0.98
135 CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. J Immunol 2010 0.98
136 HLA class II polymorphisms determine responses to bacterial superantigens. J Immunol 2004 0.98
137 Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation. J Immunol 2011 0.98
138 Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections. Curr Opin HIV AIDS 2010 0.98
139 HLA B*5701-positive long-term nonprogressors/elite controllers are not distinguished from progressors by the clonal composition of HIV-specific CD8+ T cells. J Virol 2012 0.97
140 Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individuals. Int Immunol 2005 0.97
141 Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. J Virol 2012 0.97
142 In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins. Clin Cancer Res 2005 0.96
143 Alloreactive T cell clonotype recruitment in a mixed lymphocyte reaction: implications for graft engineering. Exp Hematol 2006 0.95
144 Identification and in vitro expansion of CD4+ and CD8+ T cells specific for human neutrophil elastase. Blood 2003 0.95
145 Systemic vaccination prevents the total destruction of mucosal CD4 T cells during acute SIV challenge. J Med Primatol 2006 0.94
146 Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expression. J Immunol Methods 2011 0.93
147 Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity. J Immunol 2009 0.92
148 Maintenance of naïve CD8 T cells in nonagenarians by leptin, IGFBP3 and T3. Mech Ageing Dev 2009 0.92
149 Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus. J Virol 2002 0.91
150 Alloreactivity across HLA barriers is mediated by both naïve and antigen-experienced T cells. Biol Blood Marrow Transplant 2011 0.91
151 Evaluation of the pathogenesis of decreasing CD4(+) T cell counts in human immunodeficiency virus type 1-infected patients receiving successfully suppressive antiretroviral therapy. J Infect Dis 2009 0.90
152 Lack of in vivo compartmentalization among HIV-1 infected naïve and memory CD4+ T cell subsets. Virology 2009 0.90
153 GM-CSF production allows the identification of immunoprevalent antigens recognized by human CD4+ T cells following smallpox vaccination. PLoS One 2011 0.90
154 Suppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection. J Virol 2013 0.89
155 Limited maintenance of vaccine-induced simian immunodeficiency virus-specific CD8 T-cell receptor clonotypes after virus challenge. J Virol 2008 0.89
156 Novel recombinant Mycobacterium bovis BCG, ovine atadenovirus, and modified vaccinia virus Ankara vaccines combine to induce robust human immunodeficiency virus-specific CD4 and CD8 T-cell responses in rhesus macaques. J Virol 2010 0.89
157 Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response. Blood 2009 0.89
158 Reconstitution of CD4 T cells in bronchoalveolar lavage fluid after initiation of highly active antiretroviral therapy. J Virol 2010 0.89
159 T cells containing T cell receptor excision circles are inversely related to HIV replication and are selectively and rapidly released into circulation with antiretroviral treatment. AIDS 2003 0.89
160 Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression. J Virol 2012 0.88
161 Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes. Eur J Immunol 2010 0.88
162 Early reconstitution of the T-cell repertoire after non-myeloablative peripheral blood stem cell transplantation is from post-thymic T-cell expansion and is unaffected by graft-versus-host disease or mixed chimaerism. Br J Haematol 2003 0.88
163 Increased thymic output during acute measles virus infection. J Virol 2003 0.88
164 Antigen-specific T-cell memory is preserved in children treated for acute lymphoblastic leukemia. Blood 2005 0.87
165 Cytopenia and leukocyte recovery shape cytokine fluctuations after myeloablative allogeneic hematopoietic stem cell transplantation. Haematologica 2011 0.87
166 Immunologic pressure within class I-restricted cognate human immunodeficiency virus epitopes during highly active antiretroviral therapy. J Virol 2005 0.87
167 Extraction and characterization of the rhesus macaque T-cell receptor beta-chain genes. Immunol Cell Biol 2009 0.87
168 Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods. BMC Immunol 2014 0.86
169 Safety and tolerability of a live oral Salmonella typhimurium vaccine candidate in SIV-infected nonhuman primates. Vaccine 2013 0.84
170 Simian immunodeficiency virus SIVmac239Deltanef vaccination elicits different Tat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques. J Virol 2011 0.83
171 In vitro culture during retroviral transduction improves thymic repopulation and output after total body irradiation and autologous peripheral blood progenitor cell transplantation in rhesus macaques. Stem Cells 2006 0.83
172 Neither microbial translocation nor TLR responsiveness are likely explanations for preexisting immune activation in women who subsequently acquired HIV in CAPRISA 004. J Acquir Immune Defic Syndr 2013 0.83
173 Validation of RNA-based molecular clonotype analysis for virus-specific CD8+ T-cells in formaldehyde-fixed specimens isolated from peripheral blood. J Immunol Methods 2007 0.82
174 Quantification of T-cell receptor excision circle DNA using fluorescence resonance energy transfer and the LightCycler system. J Immunol Methods 2002 0.82
175 Comparison of plasma viremia and antibody responses in macaques inoculated with envelope variants of single-cycle simian immunodeficiency virus differing in infectivity and cellular tropism. J Virol 2007 0.82
176 Universal and specific quantitative detection of botulinum neurotoxin genes. BMC Microbiol 2010 0.82
177 Unusual immunophenotype of CD8+ T cells in familial hemophagocytic lymphohistiocytosis. Blood 2004 0.81
178 Contribution of TCR-beta locus and HLA to the shape of the mature human Vbeta repertoire. J Immunol 2008 0.81
179 Flow cytometric analysis of human antigen-specific T-cell proliferation. Methods Cell Biol 2004 0.80
180 CMV driven CD8(+) T-cell activation is associated with acute rejection in lung transplantation. Clin Immunol 2013 0.80
181 Evolution of the donor T-cell repertoire in recipients in the second decade after allogeneic stem cell transplantation. Blood 2011 0.79
182 IL-7, the thymus, and naïve T cells. Adv Exp Med Biol 2002 0.79
183 High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance. J Virol 2013 0.78
184 Evaluation of thymic output by measurement of T-cell-receptor gene rearrangement excisional circles (TREC) in patients who have received fludarabine. Leuk Lymphoma 2003 0.78
185 Adult human liver contains CD8pos T cells with naive phenotype, but is not a site for conventional alpha beta T cell development. J Immunol 2004 0.77
186 Infection and disease: cause and cure. J Pathol 2006 0.76
187 Sometimes help may not be enough. AIDS 2003 0.75
188 Risk factors for rare diseases can be risky to define: PML and natalizumab. Neurology 2013 0.75
189 Low T cell receptor excision circle levels in patients thymectomized 25-54 years ago. Immunol Lett 2003 0.75
190 Two demyelinating diseases in the brain of a single patient, PML and MS: how to minimize 'one' while treating the 'other'. Expert Rev Clin Immunol 2013 0.75