Pattern recognition scavenger receptor CD204 attenuates Toll-like receptor 4-induced NF-kappaB activation by directly inhibiting ubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6.

PubWeight™: 1.32‹?› | Rank: Top 10%

🔗 View Article (PMC 3099696)

Published in J Biol Chem on April 01, 2011

Authors

Xiaofei Yu1, Huanfa Yi, Chunqing Guo, Daming Zuo, Yanping Wang, Hyung L Kim, John R Subjeck, Xiang-Yang Wang

Author Affiliations

1: Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

Articles citing this

Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. PLoS One (2015) 1.42

Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation. PLoS One (2013) 1.14

Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages. Biochim Biophys Acta (2012) 1.12

Scavenger receptor class a plays a central role in mediating mortality and the development of the pro-inflammatory phenotype in polymicrobial sepsis. PLoS Pathog (2012) 1.10

MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx. J Immunol (2012) 1.01

Therapeutic cancer vaccines: past, present, and future. Adv Cancer Res (2013) 0.99

Targeting the immunoregulator SRA/CD204 potentiates specific dendritic cell vaccine-induced T-cell response and antitumor immunity. Cancer Res (2011) 0.96

Dysregulation of macrophage activation profiles by engineered nanoparticles. ACS Nano (2013) 0.96

Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury. Hepatology (2013) 0.94

Suppression of antigen-specific CD4+ T cell activation by SRA/CD204 through reducing the immunostimulatory capability of antigen-presenting cell. J Mol Med (Berl) (2011) 0.92

A multifunctional chimeric chaperone serves as a novel immune modulator inducing therapeutic antitumor immunity. Cancer Res (2013) 0.91

Identification of an interleukin 13-induced epigenetic signature in allergic airway inflammation. Am J Transl Res (2012) 0.89

Scavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activation. PLoS One (2015) 0.86

Pattern recognition scavenger receptor A/CD204 regulates airway inflammatory homeostasis following organic dust extract exposures. J Immunotoxicol (2014) 0.85

In situ vaccination with CD204 gene-silenced dendritic cell, not unmodified dendritic cell, enhances radiation therapy of prostate cancer. Mol Cancer Ther (2012) 0.84

Scavenger receptor-A (CD204): a two-edged sword in health and disease. Crit Rev Immunol (2014) 0.83

Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease. Int J Med Sci (2013) 0.83

Cysteine-rich domain of scavenger receptor AI modulates the efficacy of surface targeting and mediates oligomeric Aβ internalization. J Biomed Sci (2013) 0.81

High molecular weight stress proteins: Identification, cloning and utilisation in cancer immunotherapy. Int J Hyperthermia (2013) 0.81

Oxidative stress decreases functional airway mannose binding lectin in COPD. PLoS One (2014) 0.80

Poxviral protein A52 stimulates p38 mitogen-activated protein kinase (MAPK) activation by causing tumor necrosis factor receptor-associated factor 6 (TRAF6) self-association leading to transforming growth factor β-activated kinase 1 (TAK1) recruitment. J Biol Chem (2013) 0.80

Prolonged survival of scavenger receptor class A-deficient mice from pulmonary Mycobacterium tuberculosis infection. Tuberculosis (Edinb) (2011) 0.80

Class A1 scavenger receptors in cardiovascular diseases. Br J Pharmacol (2015) 0.79

Activated scavenger receptor A promotes glial internalization of aβ. PLoS One (2014) 0.79

Deletion of scavenger receptor A gene in mice resulted in protection from septic shock and modulation of TLR4 signaling in isolated peritoneal macrophages. Innate Immun (2012) 0.79

Small molecule inhibits activity of scavenger receptor A: Lead identification and preliminary studies. Bioorg Med Chem Lett (2015) 0.78

Role of scavenger receptors in glia-mediated neuroinflammatory response associated with Alzheimer's disease. Mediators Inflamm (2013) 0.78

Scavenger Receptors: Emerging Roles in Cancer Biology and Immunology. Adv Cancer Res (2015) 0.77

Antagonizing the innate pattern recognition receptor CD204 to improve dendritic cell-targeted cancer immunotherapy. Oncoimmunology (2012) 0.77

Activation of the MDA-5-IPS-1 Viral Sensing Pathway Induces Cancer Cell Death and Type I IFN-Dependent Antitumor Immunity. Cancer Res (2016) 0.77

Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins. Front Immunol (2016) 0.75

Design, synthesis, and characterization of rhein analogs as novel inhibitors of scavenger receptor A. Bioorg Med Chem Lett (2016) 0.75

Innate scavenger receptor-A regulates adaptive T helper cell responses to pathogen infection. Nat Commun (2017) 0.75

Articles cited by this

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol (2010) 24.08

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell (2006) 18.81

Recognition of microorganisms and activation of the immune response. Nature (2007) 12.99

TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature (2001) 11.84

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell (2000) 10.90

Negative regulation of toll-like receptor-mediated immune responses. Nat Rev Immunol (2005) 9.70

IgG Fc receptors. Annu Rev Immunol (2001) 8.63

Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med (2003) 7.38

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins. Nucleic Acids Res (2003) 6.86

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection. Nature (1997) 5.55

CD36 is a sensor of diacylglycerides. Nature (2005) 5.20

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin Microbiol Rev (2003) 3.70

Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells. J Clin Invest (2002) 3.13

LPS-induced upregulation of SHIP is essential for endotoxin tolerance. Immunity (2004) 3.13

Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J (2006) 3.07

Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse's tale. J Clin Invest (2001) 2.41

Protection from lethal gram-positive infection by macrophage scavenger receptor-dependent phagocytosis. J Exp Med (2000) 2.32

The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock. J Exp Med (1997) 2.28

Combinatorial pattern recognition receptor signaling alters the balance of life and death in macrophages. Proc Natl Acad Sci U S A (2006) 2.19

Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. Mol Cell Biol (2006) 2.12

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors. Immunity (2005) 1.86

Biochemistry and cell biology of mammalian scavenger receptors. Atherosclerosis (2005) 1.85

Scavenger receptors: role in innate immunity and microbial pathogenesis. Cell Microbiol (2009) 1.73

Pattern recognition scavenger receptor SRA/CD204 down-regulates Toll-like receptor 4 signaling-dependent CD8 T-cell activation. Blood (2009) 1.47

Disparate regulation and function of the class A scavenger receptors SR-AI/II and MARCO. J Immunol (2005) 1.43

Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant. Proc Natl Acad Sci U S A (2006) 1.26

The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis. J Immunol (2004) 1.21

Role of scavenger receptor MARCO in macrophage responses to CpG oligodeoxynucleotides. J Leukoc Biol (2006) 1.15

Scavenger receptor A mediates H2O2 production and suppression of IL-12 release in murine macrophages. J Leukoc Biol (2004) 1.10

The chaperoning properties of mouse grp170, a member of the third family of hsp70 related proteins. Biochemistry (2003) 1.10

Dendritic cells require the NF-kappaB2 pathway for cross-presentation of soluble antigens. J Immunol (2008) 1.08

An accessory to the 'Trinity': SR-As are essential pathogen sensors of extracellular dsRNA, mediating entry and leading to subsequent type I IFN responses. PLoS Pathog (2010) 1.06

Scavenger receptor A dampens induction of inflammation in response to the fungal pathogen Pneumocystis carinii. Infect Immun (2007) 1.03

Uncoupling scavenger receptor A-mediated phagocytosis of bacteria from endotoxic shock resistance. Infect Immun (2009) 0.91

An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha. J Immunol (2007) 0.89

Articles by these authors

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

Human intestinal bacteria as reservoirs for antibiotic resistance genes. Trends Microbiol (2004) 3.64

Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol Clin North Am (2003) 3.44

Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens. Biochem Biophys Res Commun (2009) 3.38

Safety and efficacy of partial nephrectomy for all T1 tumors based on an international multicenter experience. J Urol (2004) 3.06

DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice. Proc Natl Acad Sci U S A (2009) 2.57

Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium. J Clin Oncol (2006) 2.09

Randomized phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer. J Clin Oncol (2007) 2.06

A signature of immune function genes associated with recurrence-free survival in breast cancer patients. Breast Cancer Res Treat (2011) 1.99

Trauma, resilience, and recovery in a high-risk African-American population. Am J Psychiatry (2008) 1.89

A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles. Proc Natl Acad Sci U S A (2004) 1.87

ER stress and its regulator X-box-binding protein-1 enhance polyIC-induced innate immune response in dendritic cells. Eur J Immunol (2011) 1.66

Cigarette smoking is an independent risk factor for type 2 diabetes: a four-year community-based prospective study. Clin Endocrinol (Oxf) (2009) 1.61

A molecular classification of papillary renal cell carcinoma. Cancer Res (2005) 1.60

Kalirin, a multifunctional Rho guanine nucleotide exchange factor, is necessary for maintenance of hippocampal pyramidal neuron dendrites and dendritic spines. J Neurosci (2003) 1.60

Use of American Society of Anesthesiologists physical status classification to assess perioperative risk in patients undergoing radical nephrectomy for renal cell carcinoma. Urology (2004) 1.60

Treatment of organ confined prostate cancer with third generation cryosurgery: preliminary multicenter experience. J Urol (2003) 1.60

An integrated approach to evaluate faculty members' research performance. Acad Med (2009) 1.56

Kalirin-7 is required for synaptic structure and function. J Neurosci (2008) 1.54

Patterns of bird functional diversity on land-bridge island fragments. J Anim Ecol (2013) 1.54

Use of the University of California Los Angeles integrated staging system to predict survival in renal cell carcinoma: an international multicenter study. J Clin Oncol (2004) 1.52

Insulin-like 3 exposure of the fetal rat gubernaculum modulates expression of genes involved in neural pathways. Biol Reprod (2010) 1.47

Pattern recognition scavenger receptor SRA/CD204 down-regulates Toll-like receptor 4 signaling-dependent CD8 T-cell activation. Blood (2009) 1.47

A review of the management of thoracolumbar burst fractures. Surg Neurol (2007) 1.45

Scavenger receptor-A negatively regulates antitumor immunity. Cancer Res (2007) 1.42

Targeted immunotherapy using reconstituted chaperone complexes of heat shock protein 110 and melanoma-associated antigen gp100. Cancer Res (2003) 1.41

Gender disparity in kidney cancer treatment: women are more likely to undergo radical excision of a localized renal mass. Urology (2013) 1.40

A neutralizing human monoclonal antibody protects african green monkeys from hendra virus challenge. Sci Transl Med (2011) 1.35

Targeting the Bcl-2 family for cancer therapy. Expert Opin Ther Targets (2012) 1.33

The interleukin-1 family of cytokines and receptors in human breast cancer: implications for tumor progression. Int J Oncol (2003) 1.33

Kalirin-7 is an essential component of both shaft and spine excitatory synapses in hippocampal interneurons. J Neurosci (2008) 1.33

The mean does not mean as much anymore: finding sub-groups for tailored therapeutics. Clin Trials (2010) 1.31

Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity. Proc Natl Acad Sci U S A (2011) 1.31

mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine Growth Factor Rev (2010) 1.30

Clinical presentation of epithelioid angiomyolipoma. Int J Urol (2007) 1.30

Preventable maternal mortality: geographic/rural-urban differences and associated factors from the population-based Maternal Mortality Surveillance System in China. BMC Public Health (2011) 1.27

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies. J Virol (2011) 1.26

Effective protection of Terminalia catappa L. leaves from damage induced by carbon tetrachloride in liver mitochondria. J Nutr Biochem (2005) 1.25

Peroxiredoxin 1 stimulates secretion of proinflammatory cytokines by binding to TLR4. J Immunol (2009) 1.24

DsbA of Pseudomonas aeruginosa is essential for multiple virulence factors. Infect Immun (2003) 1.24

Anatomy of large animal spines and its comparison to the human spine: a systematic review. Eur Spine J (2009) 1.23

HSP110-HER2/neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in HER-2/neu transgenic mice. J Immunol (2003) 1.23

RENAL nephrometry score predicts surgical outcomes of laparoscopic partial nephrectomy. BJU Int (2010) 1.22

Cystic renal cell carcinoma: biology and clinical behavior. Urol Oncol (2004) 1.22

Robot-assisted radical cystectomy and pelvic lymph node dissection: initial experience at Roswell Park Cancer Institute. Urology (2007) 1.21

Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis. J Immunol (2012) 1.21

Hsp110 and Grp170, members of the Hsp70 superfamily, bind to scavenger receptor-A and scavenger receptor expressed by endothelial cells-I. Eur J Immunol (2007) 1.20

Maternal mortality in China, 1996-2005. Int J Gynaecol Obstet (2010) 1.18

Troponin-I as a prognosticator of mortality in severe sepsis patients. J Crit Care (2010) 1.17

Suppression of 9-cis-epoxycarotenoid dioxygenase, which encodes a key enzyme in abscisic acid biosynthesis, alters fruit texture in transgenic tomato. Plant Physiol (2011) 1.17

Development of a recombinant HSP110-HER-2/neu vaccine using the chaperoning properties of HSP110. Cancer Res (2002) 1.15

Percutaneous biopsy of renal cell carcinoma underestimates nuclear grade. Urology (2010) 1.15

Immunization with tumor-derived ER chaperone grp170 elicits tumor-specific CD8+ T-cell responses and reduces pulmonary metastatic disease. Int J Cancer (2003) 1.13

Prognostic factors and selection for clinical studies of patients with kidney cancer. Crit Rev Oncol Hematol (2007) 1.13

Chaperoning function of stress protein grp170, a member of the hsp70 superfamily, is responsible for its immunoadjuvant activity. Cancer Res (2006) 1.13

Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464. Chemistry (2010) 1.12

Validation of an integrated staging system toward improved prognostication of patients with localized renal cell carcinoma in an international population. J Urol (2003) 1.12

Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studies. Lung Cancer (2011) 1.11

The chaperoning properties of mouse grp170, a member of the third family of hsp70 related proteins. Biochemistry (2003) 1.10

The acute phase protein haptoglobin regulates host immunity. J Leukoc Biol (2008) 1.10

Cloning and functional characterization of a formin-like protein (AtFH8) from Arabidopsis. Plant Physiol (2005) 1.10

Percutaneous pedicle screw fixation for neurologic intact thoracolumbar burst fractures. J Spinal Disord Tech (2010) 1.10

Time trends in oral clefts in Chinese newborns: data from the Chinese National Birth Defects Monitoring Network. Birth Defects Res A Clin Mol Teratol (2010) 1.10

The changes in maternal mortality in 1000 counties in mid-Western China by a government-initiated intervention. PLoS One (2012) 1.09

Secretable chaperone Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24. Cancer Res (2008) 1.09

Expression profiling of archival renal tumors by quantitative PCR to validate prognostic markers. Biotechniques (2007) 1.08

Methanogens: principal methylators of mercury in lake periphyton. Environ Sci Technol (2011) 1.06

Berberine inhibits doxorubicin-triggered cardiomyocyte apoptosis via attenuating mitochondrial dysfunction and increasing Bcl-2 expression. PLoS One (2012) 1.05

Manipulation of arginase expression modulates abiotic stress tolerance in Arabidopsis: effect on arginine metabolism and ROS accumulation. J Exp Bot (2013) 1.05

Posttraumatic growth in former Vietnam prisoners of war. Psychiatry (2008) 1.05

Extracellular targeting of endoplasmic reticulum chaperone glucose-regulated protein 170 enhances tumor immunity to a poorly immunogenic melanoma. J Immunol (2006) 1.05

Molecular markers for predicting prognosis of renal cell carcinoma. Urol Oncol (2007) 1.05

Prospective clinical trial of preoperative sunitinib in patients with renal cell carcinoma. J Urol (2010) 1.04

Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse. J Immunol (2011) 1.04

Superior antitumor response induced by large stress protein chaperoned protein antigen compared with peptide antigen. J Immunol (2010) 1.04

Children of low-income depressed mothers: psychiatric disorders and social adjustment. Depress Anxiety (2009) 1.04

Absence of scavenger receptor A promotes dendritic cell-mediated cross-presentation of cell-associated antigen and antitumor immune response. Immunol Cell Biol (2011) 1.04

Assessment of ligamentous injury in patients with thoracolumbar burst fractures using MRI. J Trauma (2009) 1.04

CD204 suppresses large heat shock protein-facilitated priming of tumor antigen gp100-specific T cells and chaperone vaccine activity against mouse melanoma. J Immunol (2011) 1.04