Published in Nutrition on May 01, 2011
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role. Adv Nutr (2012) 1.80
LINE-1 hypomethylation in blood and tissue samples as an epigenetic marker for cancer risk: a systematic review and meta-analysis. PLoS One (2014) 1.04
A lower degree of PBMC L1 methylation is associated with excess body weight and higher HOMA-IR in the presence of lower concentrations of plasma folate. PLoS One (2013) 0.83
LINE-1 Methylation Status Correlates Significantly to Post-Therapeutic Recurrence in Stage III Colon Cancer Patients Receiving FOLFOX-4 Adjuvant Chemotherapy. PLoS One (2015) 0.83
Cervical Microbiota Associated with Higher Grade Cervical Intraepithelial Neoplasia in Women Infected with High-Risk Human Papillomaviruses. Cancer Prev Res (Phila) (2016) 0.79
Leukocyte DNA methylation and colorectal cancer among male smokers. World J Gastrointest Oncol (2012) 0.78
Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population. Genes Nutr (2015) 0.77
A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification era. PLoS One (2014) 0.75
Global DNA Methylation, Measured by the Luminometric Methylation Assay (LUMA), Associates with Postmenopausal Breast Cancer in Non-Obese and Physically Active Women. J Cancer (2015) 0.75
Integrated approach of nutritional and molecular epidemiology, mineralogical and chemical pollutant characterisation: the protocol of a cross-sectional study in women. BMJ Open (2017) 0.75
Pediatric cancer epigenome and the influence of folate. Epigenomics (2015) 0.75
Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature. Genes Nutr (2017) 0.75
The mammalian epigenome. Cell (2007) 18.13
Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med (2003) 18.04
Cytosine methylation and the ecology of intragenomic parasites. Trends Genet (1997) 13.66
Epigenetics in human disease and prospects for epigenetic therapy. Nature (2004) 11.46
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res (2004) 7.92
Biology of mammalian L1 retrotransposons. Annu Rev Genet (2001) 6.52
Analysis of repetitive element DNA methylation by MethyLight. Nucleic Acids Res (2005) 6.49
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr (2007) 4.37
Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2007) 4.01
Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis. Oncogene (2004) 3.50
Is folic acid good for everyone? Am J Clin Nutr (2008) 3.05
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability. PLoS One (2007) 2.99
Association between global DNA hypomethylation in leukocytes and risk of breast cancer. Carcinogenesis (2009) 2.58
Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr (2006) 2.25
Utility of methylation markers in cervical cancer early detection: appraisal of the state-of-the-science. Gynecol Oncol (2008) 2.08
Hypermethylation of CpG island loci and hypomethylation of LINE-1 and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological features. J Pathol (2007) 1.96
Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer (2009) 1.94
Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women. Gastroenterology (2007) 1.83
Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue. Int J Colorectal Dis (2003) 1.69
LINE-1 hypomethylation level as a potential prognostic factor for epithelial ovarian cancer. Int J Gynecol Cancer (2007) 1.50
Local and systemic effects of cigarette smoking on folate and vitamin B-12. Am J Clin Nutr (1994) 1.45
Functions for DNA methylation in vertebrates. Cold Spring Harb Symp Quant Biol (1993) 1.34
Folate is associated with the natural history of high-risk human papillomaviruses. Cancer Res (2004) 1.18
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors. Epigenetics (2009) 1.17
Folic acid fortification and supplementation--good for some but not so good for others. Nutr Rev (2007) 1.15
Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression. Hum Pathol (2001) 1.05
Lower red blood cell folate enhances the HPV-16-associated risk of cervical intraepithelial neoplasia. Nutrition (2007) 1.00
Analysis of cytokine profiles in patients with human papillomavirus-associated neoplasms. J Natl Cancer Inst (1997) 0.99
Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification era. Cancer Prev Res (Phila) (2009) 0.99
Nutrition and immunological responsiveness. T-cell function in the offspring of lipotrope and protein-deficient rats. Immunology (1974) 0.96
Methylation status in healthy subjects with normal and high serum folate concentration. Nutrition (2008) 0.89
Dietary folate improves age-related decreases in lymphocyte function. J Nutr Biochem (2005) 0.79
β-Hydroxy-β-methylbutyrate modifies human peripheral blood mononuclear cell proliferation and cytokine production in vitro. Nutrition (2010) 0.79
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat Med (2003) 7.35
Essential role for Nix in autophagic maturation of erythroid cells. Nature (2008) 6.49
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. Cell (2012) 4.37
Fertility treatments and multiple births in the United States. N Engl J Med (2013) 3.45
Circulating complement activation in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis. Kidney Int (2012) 3.34
Multi-parametric neuroimaging reproducibility: a 3-T resource study. Neuroimage (2010) 3.32
A novel cyclosporine a drug-delivery system for prevention of human corneal rejection after high-risk keratoplasty: a clinical study. Ophthalmology (2012) 3.24
mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways. Cancer Res (2011) 3.12
Calcium flickers steer cell migration. Nature (2008) 3.01
American Cancer Society Guideline for human papillomavirus (HPV) vaccine use to prevent cervical cancer and its precursors. CA Cancer J Clin (2007) 2.81
Mobility support for health monitoring at home using wearable sensors. IEEE Trans Inf Technol Biomed (2011) 2.71
Cervical cancer prevention: new tools and old barriers. Cancer (2010) 2.68
Biomarker validation of reports of recent sexual activity: results of a randomized controlled study in Zimbabwe. Am J Epidemiol (2009) 2.57
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus. Nat Genet (2011) 2.54
Minireview: GNAS: normal and abnormal functions. Endocrinology (2004) 2.50
Condom effectiveness for reducing transmission of gonorrhea and chlamydia: the importance of assessing partner infection status. Am J Epidemiol (2004) 2.49
Nonsteroidal anti-inflammatory drugs for prevention of post-ERCP pancreatitis: a meta-analysis. Gastrointest Endosc (2012) 2.37
Perinatal outcome among singleton infants conceived through assisted reproductive technology in the United States. Obstet Gynecol (2004) 2.34
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res (2006) 2.32
Gamma-secretase gene mutations in familial acne inversa. Science (2010) 2.30
Genetic background (C57BL/6J versus FVB/N) strongly influences the severity of diabetes and insulin resistance in ob/ob mice. Endocrinology (2004) 2.22
Male circumcision and risk of HIV infection among heterosexual African American men attending Baltimore sexually transmitted disease clinics. J Infect Dis (2009) 2.22
Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. Arthritis Rheum (2013) 2.17
Condom use and risk of gonorrhea and Chlamydia: a systematic review of design and measurement factors assessed in epidemiologic studies. Sex Transm Dis (2006) 2.17
Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proc Natl Acad Sci U S A (2008) 2.15
IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1. J Clin Invest (2008) 2.15
Dumbbell-like bifunctional Au-Fe3O4 nanoparticles. Nano Lett (2005) 2.09
Stem cell pathways contribute to clinical chemoresistance in ovarian cancer. Clin Cancer Res (2011) 2.03
Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study. Blood (2014) 2.01
The utility of platelet, mean platelet volume, and red cell distribution width in the diagnosis of active Crohn's disease and intestinal tuberculosis. Saudi Med J (2013) 2.01
Partner characteristics, intensity of the intercourse, and semen exposure during use of the female condom. Am J Epidemiol (2003) 1.92
Phase 1 study of pomalidomide MTD, safety, and efficacy in patients with refractory multiple myeloma who have received lenalidomide and bortezomib. Blood (2012) 1.91
The acceptability of the female and male condom: a randomized crossover trial. Perspect Sex Reprod Health (2004) 1.90
Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents. Clin Cancer Res (2002) 1.89
Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells. Oncogene (2005) 1.89
Focal atrial tachycardia originating from the non-coronary aortic sinus: electrophysiological characteristics and catheter ablation. J Am Coll Cardiol (2006) 1.88
Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells. Am J Physiol Renal Physiol (2006) 1.86
Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood (2012) 1.83
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice. Proc Natl Acad Sci U S A (2011) 1.82
Re-evaluation of the histopathologic classification of ANCA-associated glomerulonephritis: a study of 121 patients in a single center. Nephrol Dial Transplant (2011) 1.82
Conservative management of stage I endometrial carcinoma after surgical staging. Gynecol Oncol (2002) 1.74
Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells. Clin Cancer Res (2002) 1.74
The Deep South Network for cancer control. Building a community infrastructure to reduce cancer health disparities. Cancer (2006) 1.71
Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression. Brain Behav Immun (2008) 1.71
A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling. Arthritis Rheum (2003) 1.71
Assisted reproductive technology surveillance--United States, 2006. MMWR Surveill Summ (2009) 1.70
Expression of sperm protein 17 (Sp17) in ovarian cancer. Int J Cancer (2004) 1.70
Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina. Proc Natl Acad Sci U S A (2008) 1.70
Trends in multiple births conceived using assisted reproductive technology, United States, 1997-2000. Pediatrics (2003) 1.69
Cardioprotective effects of electroacupuncture pretreatment on patients undergoing heart valve replacement surgery: a randomized controlled trial. Ann Thorac Surg (2010) 1.69
Detection of two biological markers of intercourse: prostate-specific antigen and Y-chromosomal DNA. Contraception (2013) 1.68
A semiparametric approach to estimate rapid lung function decline in cystic fibrosis. Ann Epidemiol (2013) 1.68
Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification. Nat Med (2013) 1.66
Disease-related expression of the IL6/STAT3/SOCS3 signalling pathway in ulcerative colitis and ulcerative colitis-related carcinogenesis. Gut (2009) 1.65
Role of activating FcγR gene polymorphisms in Kawasaki disease susceptibility and intravenous immunoglobulin response. Circ Cardiovasc Genet (2012) 1.65
Molecular momentum transport at fluid-solid interfaces in MEMS/NEMS: a review. Int J Mol Sci (2009) 1.65
Wnt/β-catenin signaling is differentially regulated by Gα proteins and contributes to fibrous dysplasia. Proc Natl Acad Sci U S A (2011) 1.62
End-stage renal disease in African Americans with lupus nephritis is associated with APOL1. Arthritis Rheumatol (2014) 1.62
IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis. Proc Natl Acad Sci U S A (2011) 1.61
In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus. J Natl Cancer Inst (2002) 1.61
Planning and implementation of a participatory evaluation strategy: a viable approach in the evaluation of community-based participatory programs addressing cancer disparities. Eval Program Plann (2009) 1.61
An examination of acceptability of HPV vaccination among African American women and Latina immigrants. J Womens Health (Larchmt) (2007) 1.60
The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept. Arthritis Rheum (2004) 1.55
Topiramate-associated secondary angle-closure glaucoma: a case series. Arch Ophthalmol (2002) 1.55
The renal histopathological spectrum of patients with nephrotic syndrome: an analysis of 1523 patients in a single Chinese centre. Nephrol Dial Transplant (2011) 1.54
Lynch syndrome in women less than 50 years of age with endometrial cancer. Obstet Gynecol (2008) 1.54
The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p. J Biol Chem (2003) 1.52
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet (2013) 1.52
The multiple roles for Sox2 in stem cell maintenance and tumorigenesis. Cell Signal (2013) 1.52
Assisted reproductive technology surveillance--United States, 2005. MMWR Surveill Summ (2008) 1.51
Butein induces apoptosis in human uveal melanoma cells through mitochondrial apoptosis pathway. Curr Eye Res (2012) 1.51
A network coding based routing protocol for underwater sensor networks. Sensors (Basel) (2012) 1.51
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. PLoS Genet (2011) 1.49
Comparing statistical methods for constructing large scale gene networks. PLoS One (2012) 1.49
Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting: a multicenter randomized trial. JAMA Surg (2013) 1.49
Expression of multiple human endogenous retrovirus surface envelope proteins in ovarian cancer. Int J Cancer (2007) 1.48
Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J Immunol (2007) 1.47
Experimental verification of reversed Cherenkov radiation in left-handed metamaterial. Phys Rev Lett (2009) 1.47
Detection of somatic TP53 mutations in tampons of patients with high-grade serous ovarian cancer. Obstet Gynecol (2014) 1.46
Safe conception for HIV-discordant couples: insemination with processed semen from the HIV-infected partner. Am J Obstet Gynecol (2013) 1.45
Evidence based acupuncture practice recommendations for peripheral facial paralysis. Am J Chin Med (2009) 1.45
A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity. Clin Cancer Res (2004) 1.44
Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit. Proc Natl Acad Sci U S A (2005) 1.43
Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus. Mol Ther (2003) 1.43
Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum (2009) 1.43
Assisted reproductive technology surveillance - United States, 2004. MMWR Surveill Summ (2007) 1.43
Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study. Am J Hum Genet (2010) 1.43
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis. J Clin Immunol (2008) 1.42
FAS mRNA editing in Human Systemic Lupus Erythematosus. Hum Mutat (2011) 1.42
Infertility services reported by men in the United States: national survey data. Fertil Steril (2008) 1.42
Disseminated penicilliosis, recurrent bacteremic nontyphoidal salmonellosis, and burkholderiosis associated with acquired immunodeficiency due to autoantibody against gamma interferon. Clin Vaccine Immunol (2010) 1.41
The use of adjuvant radiation therapy in patients with intermediate-risk Stages IC and II uterine corpus cancer: a patient care evaluation study from the American College of Surgeons National Cancer Data Base. Gynecol Oncol (2005) 1.41
Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients. Cancer Res (2008) 1.41
Quantitation of HERV-K env gene expression and splicing in human breast cancer. Oncogene (2003) 1.41