Published in J Nutr on January 01, 2006
Folic acid and risk of prostate cancer: results from a randomized clinical trial. J Natl Cancer Inst (2009) 2.64
Folic acid supplements in pregnancy and early childhood respiratory health. Arch Dis Child (2008) 2.06
Metabolic evidence of vitamin B-12 deficiency, including high homocysteine and methylmalonic acid and low holotranscobalamin, is more pronounced in older adults with elevated plasma folate. Am J Clin Nutr (2009) 1.76
In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations. Proc Natl Acad Sci U S A (2007) 1.72
Unmetabolized folic acid is detected in nearly all serum samples from US children, adolescents, and adults. J Nutr (2014) 1.50
Folate intake and risk of colorectal cancer and adenoma: modification by time. Am J Clin Nutr (2011) 1.45
Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification. Pediatrics (2009) 1.44
The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake. Proc Natl Acad Sci U S A (2009) 1.42
Circulating folic acid in plasma: relation to folic acid fortification. Am J Clin Nutr (2008) 1.35
Folate: a magic bullet or a double edged sword for colorectal cancer prevention? Gut (2006) 1.34
Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged > or =60 y in the United States. Am J Clin Nutr (2010) 1.32
Folate and one-carbon metabolism nutrients from supplements and diet in relation to breast cancer risk. Am J Clin Nutr (2008) 1.26
The homocysteine controversy. J Inherit Metab Dis (2010) 1.23
A 19-base pair deletion polymorphism in dihydrofolate reductase is associated with increased unmetabolized folic acid in plasma and decreased red blood cell folate. J Nutr (2008) 1.22
Folate, cancer risk, and the Greek god, Proteus: a tale of two chameleons. Nutr Rev (2009) 1.21
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest (2010) 1.14
Folic acid fortification and public health: report on threshold doses above which unmetabolised folic acid appear in serum. BMC Public Health (2007) 1.13
Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev (2009) 1.11
Folic acid and prevention of colorectal adenomas: a combined analysis of randomized clinical trials. Int J Cancer (2011) 1.09
Contemporary issues surrounding folic Acid fortification initiatives. Prev Nutr Food Sci (2014) 1.05
A pivotal role of vitamin B9 in the maintenance of regulatory T cells in vitro and in vivo. PLoS One (2012) 1.02
Too much folate: a risk factor for cancer and cardiovascular disease? Curr Opin Clin Nutr Metab Care (2009) 1.02
Pre- and postfortification intake of folate and risk of colorectal cancer in a large prospective cohort study in the United States. Am J Clin Nutr (2011) 1.01
Prevention and schizophrenia--the role of dietary factors. Schizophr Bull (2010) 1.01
A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 0.99
Biomarkers of Nutrition for Development-Folate Review. J Nutr (2015) 0.98
Is it time for vitamin B-12 fortification? What are the questions? Am J Clin Nutr (2009) 0.95
Colorectal adenomas in a randomized folate trial: the role of baseline dietary and circulating folate levels. Cancer Epidemiol Biomarkers Prev (2008) 0.94
The effect of high doses of folic acid and iron supplementation in early-to-mid pregnancy on prematurity and fetal growth retardation: the mother-child cohort study in Crete, Greece (Rhea study). Eur J Nutr (2012) 0.93
Plasma folate, methylenetetrahydrofolate reductase (MTHFR), and colorectal cancer risk in three large nested case-control studies. Cancer Causes Control (2012) 0.92
Folate bioavailability: implications for establishing dietary recommendations and optimizing status. Am J Clin Nutr (2010) 0.92
Prospective study of genomic hypomethylation of leukocyte DNA and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev (2012) 0.91
Molecular mechanisms underlying the potentially adverse effects of folate. Clin Chem Lab Med (2013) 0.89
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. Am J Clin Nutr (2015) 0.89
Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake. Cancer (2012) 0.88
Determination of unmetabolized folic acid in human plasma using affinity HPLC. Am J Clin Nutr (2011) 0.86
Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort. Epigenetics (2013) 0.86
The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model. Mol Nutr Food Res (2012) 0.85
Transcobalamin 776C→G polymorphism is associated with peripheral neuropathy in elderly individuals with high folate intake. Am J Clin Nutr (2016) 0.84
[6S]-5-methyltetrahydrofolate increases plasma folate more effectively than folic acid in women with the homozygous or wild-type 677C-->T polymorphism of methylenetetrahydrofolate reductase. Br J Pharmacol (2009) 0.82
High plasma folate is negatively associated with leukocyte telomere length in Framingham Offspring cohort. Eur J Nutr (2014) 0.81
Food-Based Interventions to Modify Diet Quality and Diversity to Address Multiple Micronutrient Deficiency. Front Public Health (2016) 0.81
Natural food folate and late-life depression. J Nutr Elder (2009) 0.80
Folate intake and bowel cancer risk. Genes Nutr (2009) 0.80
Vitamin B(12) and folic acid imbalance modifies NK cytotoxicity, lymphocytes B and lymphoprolipheration in aged rats. Nutrients (2013) 0.79
Unmetabolized Folic Acid in Prediagnostic Plasma and the Risk of Colorectal Cancer. J Natl Cancer Inst (2015) 0.79
The fetal origins of the metabolic syndrome: can we intervene? J Pregnancy (2012) 0.79
Methotrexate-induced decrease in embryonic 5-methyl-tetrahydrofolate is irreversible with leucovorin supplementation. Zebrafish (2013) 0.78
Confirmation of childhood acute lymphoblastic leukemia variants, ARID5B and IKZF1, and interaction with parental environmental exposures. PLoS One (2014) 0.78
Challenges and new opportunities for clinical nutrition interventions in the aged. J Nutr (2011) 0.77
Vitamin-mediated regulation of intestinal immunity. Front Immunol (2013) 0.77
Plasma folate concentrations after a single dose ingestion of whole and skimmed folic acid fortified milks in healthy subjects. Eur J Nutr (2010) 0.77
Epigenetic synergies between biotin and folate in the regulation of pro-inflammatory cytokines and repeats. Scand J Immunol (2013) 0.77
Red blood cell folate and plasma folate are not associated with risk of incident colorectal cancer in the Women's Health Initiative observational study. Int J Cancer (2015) 0.77
Intake and Biomarkers of Folate and Risk of Cancer Morbidity in Older Adults, NHANES 1999-2002 with Medicare Linkage. PLoS One (2016) 0.76
Dihydrofolate reductase 19-bp deletion polymorphism modifies the association of folate status with memory in a cross-sectional multi-ethnic study of adults. Am J Clin Nutr (2015) 0.76
Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats. Nutrients (2016) 0.76
High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection. PLoS One (2015) 0.75
Improvement of gamete quality by stimulating and feeding the endogenous antioxidant system: mechanisms, clinical results, insights on gene-environment interactions and the role of diet. J Assist Reprod Genet (2016) 0.75
The adverse effects of an excessive folic acid intake. Eur J Clin Nutr (2016) 0.75
Reduced expression of folate transporters in kidney of a rat model of folate oversupplementation. Genes Nutr (2013) 0.75
Current Concepts of Maternal Nutrition. Obstet Gynecol Surv (2016) 0.75
Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing. Nutrients (2016) 0.75
Folate intake and the risk of endometrial cancer: A meta-analysis. Oncotarget (2016) 0.75
Folic acid induces cell type-specific changes in the transcriptome of breast cancer cell lines: a proof-of-concept study. J Nutr Sci (2016) 0.75
Mandatory fortification with folic acid in the United States appears to have adverse effects on histone methylation in women with pre-cancer but not in women free of pre-cancer. Int J Womens Health (2010) 0.75
Plasma polychlorinated biphenyl concentrations and immune function in postmenopausal women. Environ Res (2014) 0.75
Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature. Genes Nutr (2017) 0.75
Unmetabolized Folic Acid, Tetrahydrofolate and Colorectal Adenoma Risk. Cancer Prev Res (Phila) (2017) 0.75
Multiple biomarkers for the prediction of first major cardiovascular events and death. N Engl J Med (2006) 15.60
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med (2002) 11.20
Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA (2003) 10.61
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature (2012) 9.89
Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol (2003) 8.64
Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med (2011) 8.19
Study design and cohort characteristics of the Childhood Cancer Survivor Study: a multi-institutional collaborative project. Med Pediatr Oncol (2002) 8.03
Serum protein fingerprinting coupled with a pattern-matching algorithm distinguishes prostate cancer from benign prostate hyperplasia and healthy men. Cancer Res (2002) 7.11
Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med (2011) 6.89
Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design. J Natl Cancer Inst (2008) 6.79
Genetic variation and cancer: improving the environment for publication of association studies. Cancer Epidemiol Biomarkers Prev (2004) 6.24
Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol Biomarkers Prev (2007) 6.00
The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research. J Clin Oncol (2009) 5.86
Pelvic organ prolapse in the Women's Health Initiative: gravity and gravidity. Am J Obstet Gynecol (2002) 5.73
Ethnicity and breast cancer: factors influencing differences in incidence and outcome. J Natl Cancer Inst (2005) 5.52
An official American Thoracic Society clinical practice guideline: the clinical utility of bronchoalveolar lavage cellular analysis in interstitial lung disease. Am J Respir Crit Care Med (2012) 5.37
Health status of adult long-term survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. JAMA (2003) 5.27
Cause-specific late mortality among 5-year survivors of childhood cancer: the Childhood Cancer Survivor Study. J Natl Cancer Inst (2008) 5.05
Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev (2002) 5.04
Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study. J Natl Cancer Inst (2006) 4.91
Effects of aerobic exercise on mild cognitive impairment: a controlled trial. Arch Neurol (2010) 4.78
American Cancer Society Guidelines on Nutrition and Physical Activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin (2006) 4.69
Weight loss in breast cancer patient management. J Clin Oncol (2002) 4.51
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr (2007) 4.37
Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med (2004) 4.34
Antibiotic use in relation to the risk of breast cancer. JAMA (2004) 4.28
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status. Proc Natl Acad Sci U S A (2002) 4.22
Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood (2003) 4.19
Is it time to abandon the food frequency questionnaire? Cancer Epidemiol Biomarkers Prev (2005) 4.11
VITamins And Lifestyle cohort study: study design and characteristics of supplement users. Am J Epidemiol (2004) 3.97
New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Natl Cancer Inst (2006) 3.90
Physical activity, biomarkers, and disease outcomes in cancer survivors: a systematic review. J Natl Cancer Inst (2012) 3.87
Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. Arthritis Rheum (2003) 3.73
Improving gene set analysis of microarray data by SAM-GS. BMC Bioinformatics (2007) 3.68
Nutrition and physical activity during and after cancer treatment: an American Cancer Society guide for informed choices. CA Cancer J Clin (2006) 3.67
Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial. J Clin Oncol (2007) 3.58
Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients. J Clin Oncol (2009) 3.58
Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative. Am J Epidemiol (2004) 3.53
Breast cancer after childhood cancer: a report from the Childhood Cancer Survivor Study. Ann Intern Med (2004) 3.52
Long-term outcomes among adult survivors of childhood central nervous system malignancies in the Childhood Cancer Survivor Study. J Natl Cancer Inst (2009) 3.52
Diabetes, metformin, and breast cancer in postmenopausal women. J Clin Oncol (2012) 3.47
The genomic landscape of hypodiploid acute lymphoblastic leukemia. Nat Genet (2013) 3.43
Pediatric cancer survivorship research: experience of the Childhood Cancer Survivor Study. J Clin Oncol (2009) 3.38
The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations. Gastroenterology (2008) 3.35
Late mortality among 5-year survivors of childhood cancer: a summary from the Childhood Cancer Survivor Study. J Clin Oncol (2009) 3.30
α-fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C. Hepatology (2013) 3.27
Obesity, body size, and risk of postmenopausal breast cancer: the Women's Health Initiative (United States). Cancer Causes Control (2002) 3.27
Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study. Cancer (2003) 3.25
Quantification of thyroglobulin, a low-abundance serum protein, by immunoaffinity peptide enrichment and tandem mass spectrometry. Clin Chem (2008) 3.23
Effect of exercise on total and intra-abdominal body fat in postmenopausal women: a randomized controlled trial. JAMA (2003) 3.22
Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics. Nat Rev Cancer (2006) 3.19
Oral bisphosphonate use and breast cancer incidence in postmenopausal women. J Clin Oncol (2010) 3.17
Autoantibodies to folate receptors in the cerebral folate deficiency syndrome. N Engl J Med (2005) 3.17
High risk of subsequent neoplasms continues with extended follow-up of childhood Hodgkin's disease: report from the Late Effects Study Group. J Clin Oncol (2003) 3.14
Boosted decision tree analysis of surface-enhanced laser desorption/ionization mass spectral serum profiles discriminates prostate cancer from noncancer patients. Clin Chem (2002) 3.05
Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study. Am J Epidemiol (2008) 3.05
Height as an explanatory factor for sex differences in human cancer. J Natl Cancer Inst (2013) 2.99
Second neoplasms in survivors of childhood cancer: findings from the Childhood Cancer Survivor Study cohort. J Clin Oncol (2009) 2.93
Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst (2003) 2.92
A temporal association between folic acid fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev (2007) 2.91
Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles. Arthritis Rheum (2005) 2.88
Physical activity levels among breast cancer survivors. Med Sci Sports Exerc (2004) 2.88
Influence of pre- and postdiagnosis physical activity on mortality in breast cancer survivors: the health, eating, activity, and lifestyle study. J Clin Oncol (2008) 2.85
Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancer. J Natl Cancer Inst (2011) 2.84
Estrogen plus progestin therapy and breast cancer in recently postmenopausal women. Am J Epidemiol (2008) 2.79
Identification of Lynch syndrome among patients with colorectal cancer. JAMA (2012) 2.77
Risk factors for exceeding the Milan criteria after successful radiofrequency ablation in patients with early-stage hepatocellular carcinoma. Liver Transpl (2014) 2.77
Stroke as a late treatment effect of Hodgkin's Disease: a report from the Childhood Cancer Survivor Study. J Clin Oncol (2005) 2.76
Health care of young adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Ann Fam Med (2004) 2.73
Physical activity and survival in postmenopausal women with breast cancer: results from the women's health initiative. Cancer Prev Res (Phila) (2011) 2.73
Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. JAMA (2008) 2.73
Pulmonary complications in survivors of childhood and adolescent cancer. A report from the Childhood Cancer Survivor Study. Cancer (2002) 2.70
A data-analytic strategy for protein biomarker discovery: profiling of high-dimensional proteomic data for cancer detection. Biostatistics (2003) 2.69
Obesity in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. J Clin Oncol (2003) 2.68
Adiposity and sex hormones in postmenopausal breast cancer survivors. J Clin Oncol (2003) 2.65
Randomized controlled trial of the effects of print materials and step pedometers on physical activity and quality of life in breast cancer survivors. J Clin Oncol (2007) 2.65
The collaboration readiness of transdisciplinary research teams and centers findings from the National Cancer Institute's TREC Year-One evaluation study. Am J Prev Med (2008) 2.64
Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Circulation (2011) 2.62
The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. Blood (2010) 2.59
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology (2012) 2.57
Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies. J Natl Cancer Inst (2004) 2.54
Moderate-intensity exercise reduces the incidence of colds among postmenopausal women. Am J Med (2006) 2.53
Long-term neurologic and neurosensory sequelae in adult survivors of a childhood brain tumor: childhood cancer survivor study. J Clin Oncol (2003) 2.50