Published in J Mol Biol on April 06, 2011
The physical state of lipid substrates provides transacylation specificity for tafazzin. Nat Chem Biol (2012) 1.15
Fatty acid remodeling in cellular glycerophospholipids following the activation of human T cells. J Lipid Res (2013) 0.85
Substrate specificity of diacylglycerol kinase-epsilon and the phosphatidylinositol cycle. FEBS Lett (2011) 0.83
Phosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activator. J Biol Chem (2012) 0.83
Distinct properties of the two isoforms of CDP-diacylglycerol synthase. Biochemistry (2014) 0.80
Diacylglycerol Kinase-ε: Properties and Biological Roles. Front Cell Dev Biol (2016) 0.76
Arachidonoyl-Specific Diacylglycerol Kinase ε and the Endoplasmic Reticulum. Front Cell Dev Biol (2016) 0.75
Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia. Sci Rep (2017) 0.75
Prostaglandins and leukotrienes: advances in eicosanoid biology. Science (2001) 11.23
Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol (2002) 2.93
Molecular cloning and functional characterization of murine sphingosine kinase. J Biol Chem (1998) 2.92
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nat Chem Biol (2009) 2.72
Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology. J Lipid Res (2009) 2.71
Diacylglycerol kinases: at the hub of cell signalling. Biochem J (2008) 2.60
Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern. Endocrinology (1998) 2.54
Location, location, location: membrane targeting directed by PX domains. Science (2001) 2.09
Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis. Curr Biol (2005) 2.00
Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization. J Biol Chem (2002) 1.73
Cholesterol and the interaction of proteins with membrane domains. Prog Lipid Res (2006) 1.64
Diacylglycerol kinase epsilon regulates seizure susceptibility and long-term potentiation through arachidonoyl- inositol lipid signaling. Proc Natl Acad Sci U S A (2001) 1.51
Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates. J Biol Chem (1996) 1.39
Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages. J Biol Chem (1996) 1.35
Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism. J Cell Biol (2001) 1.28
Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part I: Impact of alternative halogenated privileged structures for PLD1 specificity. Bioorg Med Chem Lett (2009) 1.28
Diacylglycerol kinases. Cell Signal (2004) 1.25
The 1.85 A structure of an 8R-lipoxygenase suggests a general model for lipoxygenase product specificity. Biochemistry (2009) 1.25
Design and synthesis of isoform-selective phospholipase D (PLD) inhibitors. Part II. Identification of the 1,3,8-triazaspiro[4,5]decan-4-one privileged structure that engenders PLD2 selectivity. Bioorg Med Chem Lett (2009) 1.19
Control of free arachidonic acid levels by phospholipases A2 and lysophospholipid acyltransferases. Biochim Biophys Acta (2009) 1.18
Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction. J Neurosci (2009) 1.12
Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterol. J Biol Chem (2009) 1.10
Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol. J Biol Chem (2009) 1.10
Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase. Biochemistry (2008) 1.08
Propranolol, a phosphatidate phosphohydrolase inhibitor, also inhibits protein kinase C. J Biol Chem (1992) 1.08
Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors. Biochem Biophys Res Commun (2010) 1.04
Arachidonoyl-diacylglycerol kinase from bovine testis. Purification and properties. J Biol Chem (1994) 1.04
5-Lipoxygenase: mechanisms of regulation. J Lipid Res (2008) 1.03
Propranolol-induced inhibition of rat brain cytoplasmic phosphatidate phosphohydrolase. Neurochem Res (1983) 1.01
Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain. J Biol Chem (2010) 1.01
Leukotriene signaling in atherosclerosis and ischemia. Cardiovasc Drugs Ther (2008) 1.00
Phosphatidic acid regulates the affinity of the murine phosphatidylinositol 4-phosphate 5-kinase-Ibeta for phosphatidylinositol-4-phosphate. J Cell Biochem (2007) 0.99
Leukotriene A4 hydrolase as a target for cancer prevention and therapy. Curr Cancer Drug Targets (2004) 0.97
Polyunsaturated fatty acids, neuroinflammation and well being. Prostaglandins Leukot Essent Fatty Acids (2010) 0.96
Cholesterol-binding viral proteins in virus entry and morphogenesis. Subcell Biochem (2010) 0.96
Role of the hydrophobic segment of diacylglycerol kinase epsilon. Biochemistry (2007) 0.95
Physiological implications of the contrasting modulation of the activities of the epsilon- and zeta-isoforms of diacylglycerol kinase. Biochemistry (2001) 0.87
Interaction of mammalian seminal plasma protein PDC-109 with cholesterol: implications for a putative CRAC domain. Biochemistry (2010) 0.86
Specific primary sequence requirements for Aurora B kinase-mediated phosphorylation and subcellular localization of TMAP during mitosis. Cell Cycle (2010) 0.84
The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol. Biochemistry (2004) 0.81
Detection of phosphatidylinositol-4-phosphate 5-kinase activity using thin-layer chromatography. Methods Mol Biol (1998) 0.81
Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity. Hum Mol Genet (2007) 2.51
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. Nat Immunol (2006) 2.43
Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science (2007) 2.25
Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis. J Biol Chem (2003) 2.12
Mimicry of antimicrobial host-defense peptides by random copolymers. J Am Chem Soc (2007) 2.12
Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell (2008) 1.97
DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN. J Am Soc Nephrol (2012) 1.93
Membrane fusion. Chem Rev (2003) 1.69
Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion. Retrovirology (2011) 1.49
Regulation and functions of diacylglycerol kinases. Chem Rev (2011) 1.48
Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins). Biochim Biophys Acta (2007) 1.47
The apoptotic protein tBid promotes leakage by altering membrane curvature. J Biol Chem (2002) 1.40
Dual mechanism of bacterial lethality for a cationic sequence-random copolymer that mimics host-defense antimicrobial peptides. J Mol Biol (2008) 1.37
Tocopherols and tocotrienols in membranes: a critical review. Free Radic Biol Med (2007) 1.37
Juxtamembrane protein segments that contribute to recruitment of cholesterol into domains. Biochemistry (2006) 1.36
Correlated fluorescence-atomic force microscopy of membrane domains: structure of fluorescence probes determines lipid localization. Biophys J (2005) 1.33
Differential trafficking of the vesicular monoamine transporter-2 by methamphetamine and cocaine. Eur J Pharmacol (2002) 1.30
Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI. Mol Biol Cell (2009) 1.28
Towards a structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides. Biochem Cell Biol (2002) 1.28
Tryptophan-rich antimicrobial peptides: comparative properties and membrane interactions. Biochem Cell Biol (2002) 1.26
Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses. Proc Natl Acad Sci U S A (2010) 1.25
Diacylglycerol kinases. Cell Signal (2004) 1.25
Lipid segregation explains selective toxicity of a series of fragments derived from the human cathelicidin LL-37. Antimicrob Agents Chemother (2009) 1.24
Probing the "charge cluster mechanism" in amphipathic helical cationic antimicrobial peptides. Biochemistry (2010) 1.24
Position-dependent hydrophobicity of the antimicrobial magainin peptide affects the mode of peptide-lipid interactions and selective toxicity. Biochemistry (2002) 1.23
Role of membrane lipids in the mechanism of bacterial species selective toxicity by two alpha/beta-antimicrobial peptides. Biochim Biophys Acta (2006) 1.23
Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling. Proc Natl Acad Sci U S A (2005) 1.21
Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling. Proc Natl Acad Sci U S A (2006) 1.20
Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta. J Biol Chem (2002) 1.20
Direct evidence for membrane pore formation by the apoptotic protein Bax. Biochem Biophys Res Commun (2002) 1.20
Soluble respiratory syncytial virus fusion protein in the fully cleaved, pretriggered state is triggered by exposure to low-molarity buffer. J Virol (2011) 1.19
Mammalian diacylglycerol kinases: molecular interactions and biological functions of selected isoforms. Biochim Biophys Acta (2009) 1.17
ApoA-I mimetic peptides with differing ability to inhibit atherosclerosis also exhibit differences in their interactions with membrane bilayers. J Biol Chem (2006) 1.16
Depolarization, bacterial membrane composition, and the antimicrobial action of ceragenins. Antimicrob Agents Chemother (2010) 1.16
Aromatic residue position on the nonpolar face of class a amphipathic helical peptides determines biological activity. J Biol Chem (2004) 1.15
The physical state of lipid substrates provides transacylation specificity for tafazzin. Nat Chem Biol (2012) 1.15
Decoding the functional roles of cationic side chains of the major antimicrobial region of human cathelicidin LL-37. Antimicrob Agents Chemother (2011) 1.14
Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes. Biochem J (2004) 1.13
Ceragenins: cholic acid-based mimics of antimicrobial peptides. Acc Chem Res (2008) 1.13
Association of diacylglycerol kinase zeta with protein kinase C alpha: spatial regulation of diacylglycerol signaling. J Cell Biol (2003) 1.11
Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol. J Biol Chem (2009) 1.10
Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein. J Biol Chem (2008) 1.08
Dramatic differences in the roles in lipid metabolism of two isoforms of diacylglycerol kinase. Biochemistry (2008) 1.08
Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity. Transl Oncol (2010) 1.08
The tryptophan-rich region of HIV gp41 and the promotion of cholesterol-rich domains. Biochemistry (2005) 1.03
Myristoylation, a protruding loop, and structural plasticity are essential features of a nonenveloped virus fusion peptide motif. J Biol Chem (2004) 1.00
Structural and functional properties of an unusual internal fusion peptide in a nonenveloped virus membrane fusion protein. J Virol (2004) 1.00
Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism. Cell Signal (2004) 1.00
Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta. J Biol Chem (2003) 1.00
Antimicrobial 14-helical beta-peptides: potent bilayer disrupting agents. Biochemistry (2004) 1.00
Novel lipid transfer property of two mitochondrial proteins that bridge the inner and outer membranes. Biophys J (2006) 0.99
Comparative analysis of membrane-associated fusion peptide secondary structure and lipid mixing function of HIV gp41 constructs that model the early pre-hairpin intermediate and final hairpin conformations. J Mol Biol (2010) 0.99
Lipopolysaccharide, a key molecule involved in the synergism between temporins in inhibiting bacterial growth and in endotoxin neutralization. J Biol Chem (2008) 0.99
Diacylglycerol kinases as sources of phosphatidic acid. Biochim Biophys Acta (2009) 0.99
Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J (2009) 0.98
Cationic peptide-induced remodelling of model membranes: direct visualization by in situ atomic force microscopy. J Struct Biol (2007) 0.98
Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch. J Biol Chem (2012) 0.98
Diacylglycerol kinase-zeta localization in skeletal muscle is regulated by phosphorylation and interaction with syntrophins. Mol Biol Cell (2003) 0.98
Phosphorylation of mitochondrial phospholipid scramblase 3 by protein kinase C-delta induces its activation and facilitates mitochondrial targeting of tBid. J Cell Biochem (2007) 0.97
Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression. Cancer Lett (2008) 0.97
Amphipathic helical cationic antimicrobial peptides promote rapid formation of crystalline states in the presence of phosphatidylglycerol: lipid clustering in anionic membranes. Biophys J (2010) 0.96
Mitochondrial kinases and their molecular interaction with cardiolipin. Biochim Biophys Acta (2009) 0.96
Role of phospholipid scramblase 3 in the regulation of tumor necrosis factor-alpha-induced apoptosis. Biochemistry (2008) 0.96
On the interaction between gp41 and membranes: the immunodominant loop stabilizes gp41 helical hairpin conformation. J Mol Biol (2003) 0.96
Cardiolipin clusters and membrane domain formation induced by mitochondrial proteins. J Mol Biol (2006) 0.95
Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR. J Biol Chem (2007) 0.95
Regulation of neurite outgrowth in N1E-115 cells through PDZ-mediated recruitment of diacylglycerol kinase zeta. Mol Cell Biol (2005) 0.95
Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins. Eur J Biochem (2003) 0.95
Role of the hydrophobic segment of diacylglycerol kinase epsilon. Biochemistry (2007) 0.95
DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J (2010) 0.94
Transbilayer lipid diffusion promoted by Bax: implications for apoptosis. Biochemistry (2003) 0.94
High cationic charge and bilayer interface-binding helices in a regulatory lipid glycosyltransferase. Biochemistry (2007) 0.94
Determination of the topology of the hydrophobic segment of mammalian diacylglycerol kinase epsilon in a cell membrane and its relationship to predictions from modeling. J Mol Biol (2008) 0.94
Hydrophobic substitutions in the first residue of the CRAC segment of the gp41 protein of HIV. Biochemistry (2007) 0.93
Trichogin: a paradigm for lipopeptaibols. J Pept Sci (2003) 0.93
The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta. J Biol Chem (2005) 0.91
The role of proline in the membrane re-entrant helix of caveolin-1. J Biol Chem (2010) 0.91
Cyclooxygenase-2 transactivates the epidermal growth factor receptor through specific E-prostanoid receptors and tumor necrosis factor-alpha converting enzyme. Cell Signal (2007) 0.91
The final conformation of the complete ectodomain of the HA2 subunit of influenza hemagglutinin can by itself drive low pH-dependent fusion. J Biol Chem (2011) 0.91
Phosphatidylethanolamines modified by γ-ketoaldehyde (γKA) induce endoplasmic reticulum stress and endothelial activation. J Biol Chem (2011) 0.91
Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry (2007) 0.91
Peptide-induced domain formation in supported lipid bilayers: direct evidence by combined atomic force and polarized total internal reflection fluorescence microscopy. Biophys J (2010) 0.91
Conformational stability and membrane interaction of the full-length ectodomain of HIV-1 gp41: implication for mode of action. Biochemistry (2009) 0.91
Binding of NAP-22, a calmodulin-binding neuronal protein, to raft-like domains in model membranes. Biochemistry (2003) 0.91
Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice. J Lipid Res (2010) 0.90
CRAC motif peptide of the HIV-1 gp41 protein thins SOPC membranes and interacts with cholesterol. Biochim Biophys Acta (2008) 0.90
Cell-wall interactions and the selective bacteriostatic activity of a miniature oligo-acyl-lysyl. Biophys J (2009) 0.89
Interaction of NDPK-D with cardiolipin-containing membranes: Structural basis and implications for mitochondrial physiology. Biochimie (2009) 0.89
Direct comparison of membrane interactions of model peptides composed of only Leu and Lys residues. Biopolymers (2003) 0.88
Bacterial species selective toxicity of two isomeric alpha/beta-peptides: role of membrane lipids. Mol Membr Biol (2005) 0.87
Membrane fusion activity of vesicular stomatitis virus glycoprotein G is induced by low pH but not by heat or denaturant. Virology (2003) 0.87
Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8. J Biol Chem (2010) 0.87
High temperature stabilization of DNA in complexes with cationic lipids. Biophys J (2002) 0.86
Tracking peptide-membrane interactions: insights from in situ coupled confocal-atomic force microscopy imaging of NAP-22 peptide insertion and assembly. J Struct Biol (2006) 0.86