Published in PLoS Genet on April 07, 2011
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Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biol Psychiatry (2011) 2.45
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An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
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Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents. Hepatology (2011) 1.79
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A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology (2010) 1.71
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The impacts of errors in individual genotyping and DNA pooling on association studies. Genet Epidemiol (2004) 1.52
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Genomic evidence for COP1 as a repressor of light-regulated gene expression and development in Arabidopsis. Plant Cell (2002) 1.52
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Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology (2011) 1.50
Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest (2009) 1.49
FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs. BMC Med Genet (2008) 1.48
Protein-DNA interaction mapping using genomic tiling path microarrays in Drosophila. Proc Natl Acad Sci U S A (2003) 1.46
Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease. Hum Mol Genet (2002) 1.44
A comparison of several methods for haplotype frequency estimation and haplotype reconstruction for tightly linked markers from general pedigrees. Genet Epidemiol (2006) 1.43
Molecular architecture of the chick vestibular hair bundle. Nat Neurosci (2013) 1.43
Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito. Evolution (2013) 1.42
Finding genetic contributions to sporadic disease: a recessive locus at 12q24 commonly contributes to patent ductus arteriosus. Proc Natl Acad Sci U S A (2002) 1.42
Analysis of far-red light-regulated genome expression profiles of phytochrome A pathway mutants in Arabidopsis. Plant J (2002) 1.40
VitaPad: visualization tools for the analysis of pathway data. Bioinformatics (2004) 1.39
Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative gene. Mamm Genome (2004) 1.39
Analytical and clinical validity of whole-genome oligonucleotide array comparative genomic hybridization for pediatric patients with mental retardation and developmental delay. Am J Med Genet A (2008) 1.39
Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis (2011) 1.38
Detection of DNA copy number alterations using penalized least squares regression. Bioinformatics (2005) 1.38
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Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum (2006) 1.35
Pumilio 1 suppresses multiple activators of p53 to safeguard spermatogenesis. Curr Biol (2012) 1.34
Inferring protein-protein interactions through high-throughput interaction data from diverse organisms. Bioinformatics (2005) 1.33
On the use of DNA pooling to estimate haplotype frequencies. Genet Epidemiol (2003) 1.33
A genome-wide association study on obesity and obesity-related traits. PLoS One (2011) 1.33
Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry (2013) 1.32
PSMIX: an R package for population structure inference via maximum likelihood method. BMC Bioinformatics (2006) 1.32
Study of Arabidopsis thaliana resistome in response to cucumber mosaic virus infection using whole genome microarray. Plant Mol Biol (2004) 1.32
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COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method. Bioinformatics (2011) 1.29
Haplotype block structures show significant variation among populations. Genet Epidemiol (2004) 1.28
Improved risk prediction for Crohn's disease with a multi-locus approach. Hum Mol Genet (2011) 1.28
A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development. Plant Physiol (2003) 1.27
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Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J (2013) 1.22
Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. Alcohol Clin Exp Res (2008) 1.22
Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity. Am J Hum Genet (2002) 1.21
Comparison of single-nucleotide polymorphisms and microsatellites in inference of population structure. BMC Genet (2005) 1.20
Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes. Mol Med (2007) 1.19
Handling multiple testing while interpreting microarrays with the Gene Ontology Database. BMC Bioinformatics (2004) 1.19
A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. PLoS One (2011) 1.19
Quantitative trait loci in Anopheles gambiae controlling the encapsulation response against Plasmodium cynomolgi Ceylon. BMC Genet (2003) 1.19
A tiling microarray expression analysis of rice chromosome 4 suggests a chromosome-level regulation of transcription. Plant Cell (2005) 1.18
Dual macrolactonization/pyran-hemiketal formation via acylketenes: applications to the synthesis of (-)-callipeltoside A and a lyngbyaloside B model system. Angew Chem Int Ed Engl (2008) 1.17
Integrating domain knowledge with statistical and data mining methods for high-density genomic SNP disease association analysis. J Biomed Inform (2007) 1.16
Evidence for association between multiple complement pathway genes and AMD. Genet Epidemiol (2007) 1.15
Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment. BMC Genet (2005) 1.15
A comparison of methods for clustering 16S rRNA sequences into OTUs. PLoS One (2013) 1.15
Statistical methods to infer cooperative binding among transcription factors in Saccharomyces cerevisiae. Bioinformatics (2007) 1.15
A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol (2006) 1.14