Published in Environ Microbiol on April 14, 2011
High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity. Nat Rev Microbiol (2012) 3.94
Regional Isolation Drives Bacterial Diversification within Cystic Fibrosis Lungs. Cell Host Microbe (2015) 2.98
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective. Nat Rev Microbiol (2012) 2.50
Repeated, selection-driven genome reduction of accessory genes in experimental populations. PLoS Genet (2012) 1.46
Pseudomonas aeruginosa Genomic Structure and Diversity. Front Microbiol (2011) 1.43
Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection. Sci Rep (2015) 1.28
Tangled bank of experimentally evolved Burkholderia biofilms reflects selection during chronic infections. Proc Natl Acad Sci U S A (2012) 1.23
Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients. J Bacteriol (2012) 1.20
Within-host evolution of Pseudomonas aeruginosa reveals adaptation toward iron acquisition from hemoglobin. MBio (2014) 1.18
Pseudomonas aeruginosa exhibits frequent recombination, but only a limited association between genotype and ecological setting. PLoS One (2012) 1.17
Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa. MBio (2014) 1.16
Extensive diversification is a common feature of Pseudomonas aeruginosa populations during respiratory infections in cystic fibrosis. J Cyst Fibros (2013) 1.12
Coexistence and within-host evolution of diversified lineages of hypermutable Pseudomonas aeruginosa in long-term cystic fibrosis infections. PLoS Genet (2014) 1.12
The Pseudomonas aeruginosa reference strain PA14 displays increased virulence due to a mutation in ladS. PLoS One (2011) 1.09
Comparative genomics of isolates of a Pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients. PLoS One (2014) 1.09
Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs-A Review. Pathogens (2014) 1.05
Adaptation of iron homeostasis pathways by a Pseudomonas aeruginosa pyoverdine mutant in the cystic fibrosis lung. J Bacteriol (2014) 1.02
Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2013) 1.01
Pseudomonas aeruginosa Evolutionary Adaptation and Diversification in Cystic Fibrosis Chronic Lung Infections. Trends Microbiol (2016) 0.98
Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis. PLoS One (2012) 0.97
Selective Sweeps and Parallel Pathoadaptation Drive Pseudomonas aeruginosa Evolution in the Cystic Fibrosis Lung. MBio (2015) 0.96
Emergence of a mutL mutation causing multilocus sequence typing-pulsed-field gel electrophoresis discrepancy among Pseudomonas aeruginosa isolates from a cystic fibrosis patient. J Clin Microbiol (2012) 0.95
General and inducible hypermutation facilitate parallel adaptation in Pseudomonas aeruginosa despite divergent mutation spectra. Proc Natl Acad Sci U S A (2012) 0.91
Developing an international Pseudomonas aeruginosa reference panel. Microbiologyopen (2013) 0.91
Sub-inhibitory concentrations of some antibiotics can drive diversification of Pseudomonas aeruginosa populations in artificial sputum medium. BMC Microbiol (2013) 0.90
Lipopolysaccharide modification in Gram-negative bacteria during chronic infection. FEMS Microbiol Rev (2016) 0.88
Phenotypic diversity within a Pseudomonas aeruginosa population infecting an adult with cystic fibrosis. Sci Rep (2015) 0.86
Intraclonal genome diversity of Pseudomonas aeruginosa clones CHA and TB. BMC Genomics (2013) 0.86
Genome-wide patterns of recombination in the opportunistic human pathogen Pseudomonas aeruginosa. Genome Biol Evol (2014) 0.85
Variation of Burkholderia cenocepacia virulence potential during cystic fibrosis chronic lung infection. Virulence (2016) 0.85
Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum. Front Microbiol (2014) 0.84
Experimental evolution in biofilm populations. FEMS Microbiol Rev (2016) 0.84
In vitro and in vivo antibacterial activity of environmental bacteriophages against Pseudomonas aeruginosa strains from cystic fibrosis patients. Appl Microbiol Biotechnol (2015) 0.83
Whole-genome comparison of Aspergillus fumigatus strains serially isolated from patients with aspergillosis. J Clin Microbiol (2014) 0.83
The cystic fibrosis lower airways microbial metagenome. ERJ Open Res (2016) 0.82
A novel Pseudomonas aeruginosa bacteriophage, Ab31, a chimera formed from temperate phage PAJU2 and P. putida lytic phage AF: characteristics and mechanism of bacterial resistance. PLoS One (2014) 0.82
Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients. BMC Microbiol (2015) 0.80
A gacS deletion in Pseudomonas aeruginosa cystic fibrosis isolate CHA shapes its virulence. PLoS One (2014) 0.78
Pseudomonas aeruginosa Genome Evolution in Patients and under the Hospital Environment. Pathogens (2014) 0.78
Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14. Environ Microbiol Rep (2016) 0.76
Genome analysis of environmental and clinical P. aeruginosa isolates from sequence type-1146. PLoS One (2014) 0.76
Bacterial evolution in PCD and CF patients follows the same mutational steps. Sci Rep (2016) 0.75
Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering. Front Microbiol (2016) 0.75
Refined analyses suggest that recombination is a minor source of genomic diversity in Pseudomonas aeruginosa chronic cystic fibrosis infections. Microb Genom (2016) 0.75
Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection. BMC Genomics (2015) 0.75
Within-Host Evolution of the Dutch High-Prevalent Pseudomonas aeruginosa Clone ST406 during Chronic Colonization of a Patient with Cystic Fibrosis. PLoS One (2016) 0.75
The effect of loss of O-antigen ligase on phagocytic susceptibility of motile and non-motile Pseudomonas aeruginosa. Mol Immunol (2017) 0.75
Burkholderia cenocepacia virulence microevolution in the CF lung: Variations on a theme. Virulence (2016) 0.75
Recent advances in understanding Pseudomonas aeruginosa as a pathogen. F1000Res (2017) 0.75
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med (2008) 3.41
Population structure of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2007) 2.56
Activities of Pseudomonas aeruginosa effectors secreted by the Type III secretion system in vitro and during infection. Infect Immun (2005) 2.51
Highly adherent small-colony variants of Pseudomonas aeruginosa in cystic fibrosis lung infection. J Med Microbiol (2003) 2.17
Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone. J Bacteriol (2002) 2.14
Quorum sensing: the power of cooperation in the world of Pseudomonas. Environ Microbiol (2005) 2.12
Pseudomonas aeruginosa microevolution during cystic fibrosis lung infection establishes clones with adapted virulence. Am J Respir Crit Care Med (2009) 2.08
Sequence analysis of the mobile genome island pKLC102 of Pseudomonas aeruginosa C. J Bacteriol (2004) 2.04
The neglected intrinsic resistome of bacterial pathogens. PLoS One (2008) 1.82
A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. J Bacteriol (2005) 1.74
Genome diversity of Pseudomonas aeruginosa PAO1 laboratory strains. J Bacteriol (2009) 1.73
Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease. Hum Mutat (2009) 1.71
Intestinal current measurement for diagnostic classification of patients with questionable cystic fibrosis: validation and reference data. Thorax (2010) 1.61
Pseudomonas aeruginosa Genomic Structure and Diversity. Front Microbiol (2011) 1.43
Diversity of the abundant pKLC102/PAGI-2 family of genomic islands in Pseudomonas aeruginosa. J Bacteriol (2006) 1.43
Expression analysis of a highly adherent and cytotoxic small colony variant of Pseudomonas aeruginosa isolated from a lung of a patient with cystic fibrosis. J Bacteriol (2004) 1.43
The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases. Proc Natl Acad Sci U S A (2006) 1.39
Global features of the Pseudomonas putida KT2440 genome sequence. Environ Microbiol (2002) 1.39
Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage patterns. BMC Bioinformatics (2004) 1.34
Global regulation of quorum sensing and virulence by VqsR in Pseudomonas aeruginosa. Microbiology (2004) 1.32
Genes that determine immunology and inflammation modify the basic defect of impaired ion conductance in cystic fibrosis epithelia. J Med Genet (2010) 1.26
Structure of Pseudomonas aeruginosa populations analyzed by single nucleotide polymorphism and pulsed-field gel electrophoresis genotyping. J Bacteriol (2004) 1.24
Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Microbiology (2006) 1.20
Biological cost of hypermutation in Pseudomonas aeruginosa strains from patients with cystic fibrosis. Microbiology (2007) 1.20
Pseudomonas aeruginosa and Burkholderia cepacia in cystic fibrosis: genome evolution, interactions and adaptation. Int J Med Microbiol (2004) 1.18
Autophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiae. Genetics (2010) 1.17
Caenorhabditis elegans semi-automated liquid screen reveals a specialized role for the chemotaxis gene cheB2 in Pseudomonas aeruginosa virulence. PLoS Pathog (2009) 1.15
The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis. Hum Genet (2004) 1.14
The genome structure of Pseudomonas putida: high-resolution mapping and microarray analysis. Environ Microbiol (2002) 1.13
Think big--giant genes in bacteria. Environ Microbiol (2008) 1.13
Origins of cystic fibrosis lung disease. N Engl J Med (2015) 1.12
Genome-wide transcriptional profiling of the steady-state response of Pseudomonas aeruginosa to hydrogen peroxide. J Bacteriol (2005) 1.10
Functional genomics of stress response in Pseudomonas putida KT2440. J Bacteriol (2006) 1.09
Differentiation of regions with atypical oligonucleotide composition in bacterial genomes. BMC Bioinformatics (2005) 1.08
Inter- and intraclonal diversity of the Pseudomonas aeruginosa proteome manifests within the secretome. J Bacteriol (2003) 1.07
Characterization of poxB, a chromosomal-encoded Pseudomonas aeruginosa oxacillinase. Gene (2005) 1.06
Genes in the vicinity of CFTR modulate the cystic fibrosis phenotype in highly concordant or discordant F508del homozygous sib pairs. Hum Genet (2002) 1.05
Ex vivo CF diagnosis by intestinal current measurements (ICM) in small aperture, circulating Ussing chambers. J Cyst Fibros (2004) 1.05
The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis. Hum Genet (2006) 1.05
Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment. Environ Microbiol (2014) 1.04
Clonal epidemiology of Pseudomonas aeruginosa in cystic fibrosis. Int J Med Microbiol (2010) 1.04
Genometa--a fast and accurate classifier for short metagenomic shotgun reads. PLoS One (2012) 1.02
Basic protocol for transepithelial nasal potential difference measurements. J Cyst Fibros (2004) 1.01
Pseudomonas aeruginosa population biology in chronic obstructive pulmonary disease. J Infect Dis (2009) 1.01
Fitness of isogenic colony morphology variants of Pseudomonas aeruginosa in murine airway infection. PLoS One (2008) 0.99
Genome Sequence of Burkholderia cenocepacia H111, a Cystic Fibrosis Airway Isolate. Genome Announc (2014) 0.98
GeneChip expression analysis of the VqsR regulon of Pseudomonas aeruginosa TB. FEMS Microbiol Lett (2005) 0.98
Multiple roles of Pseudomonas aeruginosa TBCF10839 PilY1 in motility, transport and infection. Mol Microbiol (2008) 0.97
Molecular epidemiology of chronic Pseudomonas aeruginosa airway infections in cystic fibrosis. PLoS One (2012) 0.97
Intraclonal diversity of the Pseudomonas aeruginosa cystic fibrosis airway isolates TBCF10839 and TBCF121838: distinct signatures of transcriptome, proteome, metabolome, adherence and pathogenicity despite an almost identical genome sequence. Environ Microbiol (2012) 0.97
Antibiotic treatment of CF lung disease: from bench to bedside. J Cyst Fibros (2011) 0.96
Crystal structure of the electron transfer complex rubredoxin rubredoxin reductase of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2007) 0.95
Accumulation of ceramide in the trachea and intestine of cystic fibrosis mice causes inflammation and cell death. Biochem Biophys Res Commun (2010) 0.94
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes through oligonucleotide usage. BMC Bioinformatics (2008) 0.93
EuroCareCF quality assessment of diagnostic microbiology of cystic fibrosis isolates. J Clin Microbiol (2009) 0.93
Functional analysis of F508del CFTR in native human colon. Biochim Biophys Acta (2010) 0.92
A new role of the complement system: C3 provides protection in a mouse model of lung infection with intracellular Chlamydia psittaci. PLoS One (2012) 0.92
Developing an international Pseudomonas aeruginosa reference panel. Microbiologyopen (2013) 0.91
Complete Genome Sequence of Persistent Cystic Fibrosis Isolate Pseudomonas aeruginosa Strain RP73. Genome Announc (2013) 0.91
Murine pulmonary infection with Listeria monocytogenes: differential susceptibility of BALB/c, C57BL/6 and DBA/2 mice. Microbes Infect (2005) 0.91
In silico comparison of pKLC102-like genomic islands of Pseudomonas aeruginosa. FEMS Microbiol Lett (2007) 0.91
In-vivo expression profiling of Pseudomonas aeruginosa infections reveals niche-specific and strain-independent transcriptional programs. PLoS One (2011) 0.89
Pseudomonas putida KT2440 genome update by cDNA sequencing and microarray transcriptomics. Environ Microbiol (2011) 0.89
Spontaneous rescue from cystic fibrosis in a mouse model. BMC Genet (2006) 0.87
Intraclonal genome diversity of Pseudomonas aeruginosa clones CHA and TB. BMC Genomics (2013) 0.86
Functional genomics of Pseudomonas aeruginosa to identify habitat-specific determinants of pathogenicity. Int J Med Microbiol (2007) 0.86
Advances in computational analysis of metagenome sequences. Environ Microbiol (2012) 0.84
Comparative genomics of green sulfur bacteria. Photosynth Res (2010) 0.83
The extensive set of accessory Pseudomonas aeruginosa genomic components. FEMS Microbiol Lett (2014) 0.83
An association study on contrasting cystic fibrosis endophenotypes recognizes KRT8 but not KRT18 as a modifier of cystic fibrosis disease severity and CFTR mediated residual chloride secretion. BMC Med Genet (2011) 0.83
An intragenic deletion in pilQ leads to nonpiliation of a Pseudomonas aeruginosa strain isolated from cystic fibrosis lung. FEMS Microbiol Lett (2007) 0.83
Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6. Hum Genet (2010) 0.83
Lung function and inflammation during murine Pseudomonas aeruginosa airway infection. Immunobiology (2011) 0.83
Role of CD95 in pulmonary inflammation and infection in cystic fibrosis. J Mol Med (Berl) (2012) 0.82
Instability of the insertional mutation in CftrTgH(neoim)Hgu cystic fibrosis mouse model. BMC Genet (2004) 0.82
Acute intratracheal Pseudomonas aeruginosa infection in cystic fibrosis mice is age-independent. Respir Res (2011) 0.82
Beneficial effects of TLR-2/6 ligation in pulmonary bacterial infection and immunization with Pseudomonas aeruginosa. Inflammation (2010) 0.82
Visualization of Pseudomonas genomic structure by abundant 8-14mer oligonucleotides. Environ Microbiol (2009) 0.81
Feasibility and variability of measuring the Lung Clearance Index in a multi-center setting. Pediatr Pulmonol (2011) 0.81
Transmission ratio distortion and maternal effects confound the analysis of modulators of cystic fibrosis disease severity on 19q13. Eur J Hum Genet (2007) 0.81
Transcript profiling of the Pseudomonas aeruginosa genomic islands PAGI-2 and pKLC102. Microbiology (2008) 0.81
Global features of the Alcanivorax borkumensis SK2 genome. Environ Microbiol (2007) 0.81
Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation. Eur J Hum Genet (2011) 0.81
Proteome analysis of intraclonal diversity of two Pseudomonas aeruginosa TB clone isolates. Proteomics (2004) 0.80