Published in Curr Opin Chem Biol on April 12, 2011
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. Chem Soc Rev (2015) 1.74
Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine. PLoS Comput Biol (2011) 1.33
Protein design: toward functional metalloenzymes. Chem Rev (2014) 1.17
Computational design of membrane proteins. Structure (2012) 0.95
Effective inter-residue contact definitions for accurate protein fold recognition. BMC Bioinformatics (2012) 0.84
Optimizing scoring function of protein-nucleic acid interactions with both affinity and specificity. PLoS One (2013) 0.81
Computational design of a Diels-Alderase from a thermophilic esterase: the importance of dynamics. J Comput Aided Mol Des (2012) 0.80
Computational strategies for the design of new enzymatic functions. Arch Biochem Biophys (2015) 0.78
Computational approaches for rational design of proteins with novel functionalities. Comput Struct Biotechnol J (2012) 0.78
Computational Enzyme Design: Advances, hurdles and possible ways forward. Comput Struct Biotechnol J (2012) 0.76
Application of conventional molecular dynamics simulation in evaluating the stability of apomyoglobin in urea solution. Sci Rep (2017) 0.75
Biomolecular engineering for nanobio/bionanotechnology. Nano Converg (2017) 0.75
Kemp elimination catalysts by computational enzyme design. Nature (2008) 8.19
De novo computational design of retro-aldol enzymes. Science (2008) 7.62
Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction. Science (2010) 4.32
Design of protein-interaction specificity gives selective bZIP-binding peptides. Nature (2009) 2.88
Computational design of peptides that target transmembrane helices. Science (2007) 2.28
Computational design and characterization of a monomeric helical dinuclear metalloprotein. J Mol Biol (2003) 1.60
Alteration of enzyme specificity by computational loop remodeling and design. Proc Natl Acad Sci U S A (2009) 1.56
Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor. J Am Chem Soc (2005) 1.52
Programmable ligand detection system in plants through a synthetic signal transduction pathway. PLoS One (2011) 1.38
Computationally designed libraries of fluorescent proteins evaluated by preservation and diversity of function. Proc Natl Acad Sci U S A (2006) 1.38
Probing designability via a generalized model of helical bundle geometry. J Mol Biol (2010) 1.37
Structure-based prediction of the peptide sequence space recognized by natural and synthetic PDZ domains. J Mol Biol (2010) 1.32
A synthetic coiled-coil interactome provides heterospecific modules for molecular engineering. J Am Chem Soc (2010) 1.32
Computational design of water-soluble analogues of the potassium channel KcsA. Proc Natl Acad Sci U S A (2004) 1.31
De novo design of a single-chain diphenylporphyrin metalloprotein. J Am Chem Soc (2007) 1.28
Origins of catalysis by computationally designed retroaldolase enzymes. Proc Natl Acad Sci U S A (2010) 1.27
Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries. Proc Natl Acad Sci U S A (2010) 1.20
Artificial diiron proteins: from structure to function. Biopolymers (2005) 1.12
De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex. J Am Chem Soc (2010) 1.11
Computationally designed peptide inhibitors of protein-protein interactions in membranes. Biochemistry (2008) 1.05
Spectroscopic and computational studies of the de novo designed protein DF2t: correlation to the biferrous active site of ribonucleotide reductase and factors that affect O2 reactivity. J Am Chem Soc (2005) 1.03
Engineering a protein-protein interface using a computationally designed library. Proc Natl Acad Sci U S A (2010) 1.03
Solution NMR structure of a designed metalloprotein and complementary molecular dynamics refinement. Structure (2008) 1.03
Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arrays. J Am Chem Soc (2008) 1.02
NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA. Proc Natl Acad Sci U S A (2008) 1.00
Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophore. J Am Chem Soc (2010) 0.99
Experimental and computational evaluation of forces directing the association of transmembrane helices. J Am Chem Soc (2009) 0.96
Artificial di-iron proteins: solution characterization of four helix bundles containing two distinct types of inter-helical loops. J Biol Inorg Chem (2005) 0.92
Identification of interacting hot spots in the beta3 integrin stalk using comprehensive interface design. J Biol Chem (2010) 0.89
The structure of a designed diiron(III) protein: implications for cofactor stabilization and catalysis. Angew Chem Int Ed Engl (2006) 0.88
Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework. Biophys J (2008) 0.86
Metal-binding dependent disruption of membranes by designed helices. J Am Chem Soc (2009) 0.84
Three-dimensional structure and dynamics of a de novo designed, amphiphilic, metallo-porphyrin-binding protein maquette at soft interfaces by molecular dynamics simulations. J Phys Chem B (2007) 0.84
Structure and dynamics of an extended conjugated NLO chromophore within an amphiphilic 4-helix bundle peptide by molecular dynamics simulation. J Phys Chem B (2008) 0.83