Published in Circ Res on April 14, 2011
Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ Res (2012) 2.06
Posttranslational modification and quality control. Circ Res (2013) 1.06
The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16). Biochem J (2012) 1.01
Small heat shock proteins in redox metabolism: implications for cardiovascular diseases. Int J Biochem Cell Biol (2012) 0.99
ERK/PP1a/PLB/SERCA2a and JNK pathways are involved in luteolin-mediated protection of rat hearts and cardiomyocytes following ischemia/reperfusion. PLoS One (2013) 0.92
Phospholamban interactome in cardiac contractility and survival: A new vision of an old friend. J Mol Cell Cardiol (2014) 0.87
Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice. Diabetes (2016) 0.84
Loss of proteostatic control as a substrate for atrial fibrillation: a novel target for upstream therapy by heat shock proteins. Front Physiol (2012) 0.83
HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin. Mol Cell Biol (2015) 0.80
Targeted disruption of the heat shock protein 20-phosphodiesterase 4D (PDE4D) interaction protects against pathological cardiac remodelling in a mouse model of hypertrophy. FEBS Open Bio (2014) 0.79
Small heat shock proteins in cellular adhesion and migration: evidence from Plasmodium genetics. Cell Adh Migr (2012) 0.77
Identification of a protein phosphatase-1/phospholamban complex that is regulated by cAMP-dependent phosphorylation. PLoS One (2013) 0.77
Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. J Mol Cell Cardiol (2015) 0.76
Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy. Proc Natl Acad Sci U S A (2015) 0.76
The protective role of small heat shock proteins in cardiac diseases: key role in atrial fibrillation. Cell Stress Chaperones (2017) 0.75
In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome. PLoS One (2016) 0.75
PM2.5 exposure in utero contributes to neonatal cardiac dysfunction in mice. Environ Pollut (2017) 0.75
Cardiac excitation-contraction coupling. Nature (2002) 18.48
Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol (2003) 5.05
PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med (2004) 4.50
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res (2005) 2.52
Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins. Chem Biol (2006) 2.08
Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20. Circ Res (2003) 1.98
Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol (2002) 1.97
Effects of serine/threonine protein phosphatases on ion channels in excitable membranes. Physiol Rev (2000) 1.62
Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury. Circulation (2005) 1.60
Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban. Eur J Biochem (1991) 1.56
What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis? J Mol Cell Cardiol (2008) 1.55
Small heat-shock protein Hsp20 phosphorylation inhibits beta-agonist-induced cardiac apoptosis. Circ Res (2004) 1.54
Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circ Res (2009) 1.52
Serine/threonine protein phosphatases in the control of cell function. Adv Enzyme Regul (1994) 1.44
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol (2009) 1.42
Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity. Circ Res (2008) 1.40
Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts. Cardiovasc Res (2004) 1.38
Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1. Circ Res (2006) 1.35
Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts. Am J Physiol Heart Circ Physiol (2003) 1.32
Constitutively active phosphatase inhibitor-1 improves cardiac contractility in young mice but is deleterious after catecholaminergic stress and with aging. J Clin Invest (2010) 1.29
Serine/threonine protein phosphatases PP1 and PP2A are key players in apoptosis. Biochimie (2003) 1.26
Hsp20 and its cardioprotection. Trends Cardiovasc Med (2005) 1.21
Overexpression of Hsp20 prevents endotoxin-induced myocardial dysfunction and apoptosis via inhibition of NF-kappaB activation. J Mol Cell Cardiol (2009) 1.14
Proteomic analysis reveals significant alternations of cardiac small heat shock protein expression in congestive heart failure. J Card Fail (2006) 1.10
Anti-apoptotic protein Bcl-2 interacts with and destabilizes the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA). Biochem J (2004) 1.10
Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport. Circ Res (2003) 1.07
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death. Circ Res (2009) 1.05
Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy. Circulation (2006) 1.04
Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2. Cardiovasc Res (2005) 1.03
Changes in the rat heart proteome induced by exercise training: Increased abundance of heat shock protein hsp20. Proteomics (2006) 1.02
Altered phosphatase activity in heart failure, influence on Ca2+ movement. Basic Res Cardiol (2002) 1.02
Inhibition of protein phosphatase 1 by inhibitor-2 exacerbates progression of cardiac failure in a model with pressure overload. Cardiovasc Res (2008) 1.01
Localization, macromolecular associations, and function of the small heat shock-related protein HSP20 in rat heart. Circulation (2003) 0.99
The small heat shock protein, HSPB6, in muscle function and disease. Cell Stress Chaperones (2009) 0.96
Importance of small heat shock protein 20 (hsp20) C-terminal extension in cardioprotection. J Mol Cell Cardiol (2007) 0.89
Biophysical interaction between phospholamban and protein phosphatase 1 regulatory subunit GM. FEBS Lett (1998) 0.87
Targeting sarcoplasmic reticulum Ca2+ uptake to improve heart failure: hit or miss. Circ Res (2010) 0.85
Purification and characterization of phospholamban phosphatase from cardiac muscle. J Biol Chem (1988) 0.79
Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol (2003) 5.05
PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med (2004) 4.50
Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science (2003) 3.71
The BRI1-associated kinase 1, BAK1, has a brassinolide-independent role in plant cell-death control. Curr Biol (2007) 3.16
Interferon-alpha/beta-mediated innate immune mechanisms in dermatomyositis. Ann Neurol (2005) 3.07
Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium. Cardiovasc Res (2007) 2.98
Gene expression comparison of biopsies from Duchenne muscular dystrophy (DMD) and normal skeletal muscle. Proc Natl Acad Sci U S A (2002) 2.60
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. J Clin Invest (2003) 2.56
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res (2005) 2.52
Expression profiling and identification of novel genes involved in myogenic differentiation. FASEB J (2003) 2.30
Reproducibility of gene expression across generations of Affymetrix microarrays. BMC Bioinformatics (2003) 2.20
Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circ Res (2009) 2.12
Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice. Circ Res (2007) 2.07
Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res (2002) 2.06
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy. Proc Natl Acad Sci U S A (2006) 2.05
MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injury. Circulation (2010) 2.03
Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20. Circ Res (2003) 1.98
Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol (2002) 1.97
Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium. J Mol Cell Cardiol (2007) 1.94
Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling. Circulation (2009) 1.86
Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A. Endocrinology (2005) 1.84
T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase. Proc Natl Acad Sci U S A (2009) 1.83
In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function. J Mol Cell Cardiol (2006) 1.81
Reduced collagen deposition in infarcted myocardium facilitates induced pluripotent stem cell engraftment and angiomyogenesis for improvement of left ventricular function. J Am Coll Cardiol (2011) 1.74
Polycyclic aromatic hydrocarbons (PAHs) in urban surface dust of Guangzhou, China: Status, sources and human health risk assessment. Sci Total Environ (2011) 1.69
Maternal Trypanosoma cruzi infection, pregnancy outcome, morbidity, and mortality of congenitally infected and non-infected newborns in Bolivia. Am J Trop Med Hyg (2004) 1.69
HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia. J Mol Cell Cardiol (2007) 1.68
Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart. J Mol Cell Cardiol (2003) 1.68
Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death. J Mol Cell Cardiol (2010) 1.66
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death. J Clin Invest (2008) 1.65
CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. Cardiovasc Res (2006) 1.64
Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle. Circ Res (2004) 1.63
Hsp20-engineered mesenchymal stem cells are resistant to oxidative stress via enhanced activation of Akt and increased secretion of growth factors. Stem Cells (2009) 1.60
Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury. Circulation (2005) 1.60
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model. Cardiovasc Res (2004) 1.59
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circ Res (2009) 1.58
First 3D Pr(III)-Ni(II)-Na(I) polymer and a 3D Pr(III) open network based on pyridine-2,4,6-tricarboxylic acid. Inorg Chem (2006) 1.58
Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice. Circ Res (2002) 1.56
Small heat-shock protein Hsp20 phosphorylation inhibits beta-agonist-induced cardiac apoptosis. Circ Res (2004) 1.54
Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circ Res (2009) 1.52
Overexpression of histidine-rich Ca-binding protein protects against ischemia/reperfusion-induced cardiac injury. Cardiovasc Res (2007) 1.51
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity. Circulation (2007) 1.51
Dickkopf-3 attenuates pressure overload-induced cardiac remodelling. Cardiovasc Res (2014) 1.49
Role of microRNAs in the reperfused myocardium towards post-infarct remodelling. Cardiovasc Res (2011) 1.47
Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia. Stem Cells (2006) 1.46
Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am J Cardiovasc Dis (2011) 1.43
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol (2009) 1.42
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. J Clin Invest (2011) 1.42
Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity. Circ Res (2008) 1.40
Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. Circulation (2004) 1.36
Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1. Circ Res (2006) 1.35
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. J Clin Invest (2003) 1.33
Epithelial-mesenchymal transition (EMT) induced by TNF-α requires AKT/GSK-3β-mediated stabilization of snail in colorectal cancer. PLoS One (2013) 1.31
The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury. J Mol Cell Cardiol (2010) 1.31
Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase. Am J Physiol Heart Circ Physiol (2007) 1.29
Evidence by molecular profiling for a placental origin of infantile hemangioma. Proc Natl Acad Sci U S A (2005) 1.28
Congenital transmission of Trypanosoma cruzi is associated with maternal enhanced parasitemia and decreased production of interferon- gamma in response to parasite antigens. J Infect Dis (2004) 1.27
Bisphenol A and 17β-estradiol promote arrhythmia in the female heart via alteration of calcium handling. PLoS One (2011) 1.26
Role of the transient outward current (Ito) in shaping canine ventricular action potential--a dynamic clamp study. J Physiol (2005) 1.26
Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function. J Mol Cell Cardiol (2006) 1.26
Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation. Proc Natl Acad Sci U S A (2006) 1.24
Paracrine factors released by GATA-4 overexpressed mesenchymal stem cells increase angiogenesis and cell survival. Am J Physiol Heart Circ Physiol (2010) 1.23
Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure. Cardiovasc Res (2002) 1.21
Hsp20 and its cardioprotection. Trends Cardiovasc Med (2005) 1.21
The intracellular renin-angiotensin system: a new paradigm. Trends Endocrinol Metab (2007) 1.19
Human fetuses are able to mount an adultlike CD8 T-cell response. Blood (2002) 1.18
Regulation of myocardial function by histidine-rich, calcium-binding protein. Am J Physiol Heart Circ Physiol (2004) 1.18
SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells. Mol Ther (2010) 1.18
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle. Neurogenetics (2003) 1.18
The intracellular renin-angiotensin system: implications in cardiovascular remodeling. Curr Opin Nephrol Hypertens (2008) 1.17
The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. Eur Heart J (2008) 1.17
The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival. Mol Biol Cell (2008) 1.17
Fabrication of chitosan/silk fibroin composite nanofibers for wound-dressing applications. Int J Mol Sci (2010) 1.16
Ca2+ cycling and new therapeutic approaches for heart failure. Circulation (2010) 1.16
Stem cell homing and angiomyogenesis in transplanted hearts are enhanced by combined intramyocardial SDF-1alpha delivery and endogenous cytokine signaling. Am J Physiol Heart Circ Physiol (2009) 1.16