Published in Cell Stress Chaperones on May 08, 2017
Adapting proteostasis for disease intervention. Science (2008) 13.22
A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy. Nat Genet (1998) 4.75
Crystal structure and assembly of a eukaryotic small heat shock protein. Nat Struct Biol (2001) 3.69
Heat shock response modulators as therapeutic tools for diseases of protein conformation. J Biol Chem (2005) 2.95
Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27. Mol Cell Biol (1995) 2.70
Electropathological substrate of longstanding persistent atrial fibrillation in patients with structural heart disease: epicardial breakthrough. Circulation (2010) 2.56
Structural changes of atrial myocardium due to sustained atrial fibrillation in the goat. Circulation (1997) 2.52
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The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network. J Biol Chem (1998) 2.23
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Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin. J Cell Sci (1999) 1.87
L-type Ca2+ current downregulation in chronic human atrial fibrillation is associated with increased activity of protein phosphatases. Circulation (2004) 1.85
Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations. Ann Neurol (2003) 1.77
Alpha B-crystallin in cardiac tissue. Association with actin and desmin filaments. Circ Res (1992) 1.71
Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy. Circ Res (2006) 1.66
Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury. Circulation (2005) 1.60
Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation. J Biol Chem (2000) 1.50
Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27. Biochem Cell Biol (1996) 1.46
The N-terminal arm of small heat shock proteins is important for both chaperone activity and substrate specificity. J Biol Chem (2006) 1.43
Novel molecular targets for atrial fibrillation therapy. Nat Rev Drug Discov (2012) 1.42
Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease. Proc Natl Acad Sci U S A (2005) 1.42
Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation. J Biol Chem (2003) 1.42
Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1. Circ Res (2006) 1.35
HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. Autophagy (2007) 1.33
Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation. J Mol Cell Cardiol (2006) 1.31
Association of the chaperone alphaB-crystallin with titin in heart muscle. J Biol Chem (2003) 1.31
Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current. Circ Res (2008) 1.27
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Identification and characterization of cvHsp. A novel human small stress protein selectively expressed in cardiovascular and insulin-sensitive tissues. J Biol Chem (1999) 1.26
Comparison of the small heat shock proteins alphaB-crystallin, MKBP, HSP25, HSP20, and cvHSP in heart and skeletal muscle. Histochem Cell Biol (2004) 1.26
Evolution of the atrial fibrillation substrate in experimental congestive heart failure: angiotensin-dependent and -independent pathways. Cardiovasc Res (2003) 1.25
Single oral dose of geranylgeranylacetone induces heat-shock protein 72 and renders protection against ischemia/reperfusion injury in rat heart. Circulation (2001) 1.23
Induction of heat shock response protects the heart against atrial fibrillation. Circ Res (2006) 1.20
H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart. Circ Res (2005) 1.19
HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones. Hum Mol Genet (2010) 1.18
Subcellular movement and expression of HSP27, alphaB-crystallin, and HSP70 after two bouts of eccentric exercise in humans. J Appl Physiol (1985) (2009) 1.14
Over-expression of heat shock protein 27 attenuates doxorubicin-induced cardiac dysfunction in mice. Eur J Heart Fail (2007) 1.12
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H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res (2002) 1.09
Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity. Biochem J (2004) 1.09
Ischemia-induced phosphorylation and translocation of stress protein alpha B-crystallin to Z lines of myocardium. Am J Physiol (1998) 1.09
H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload. Circulation (2011) 1.09
MKBP, a novel member of the small heat shock protein family, binds and activates the myotonic dystrophy protein kinase. J Cell Biol (1998) 1.09
Small heat shock protein 20 (HspB6) in cardiac hypertrophy and failure. J Mol Cell Cardiol (2010) 1.08
Small heat shock proteins: Role in cellular functions and pathology. Biochim Biophys Acta (2014) 1.07
Exercise training restores cardiac protein quality control in heart failure. PLoS One (2012) 1.06
Activation of proteolysis by calpains and structural changes in human paroxysmal and persistent atrial fibrillation. Cardiovasc Res (2002) 1.05
Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death. Circ Res (2009) 1.05
Interruption of CryAB-amyloid oligomer formation by HSP22. J Biol Chem (2006) 1.03
Changes in the rat heart proteome induced by exercise training: Increased abundance of heat shock protein hsp20. Proteomics (2006) 1.02
Association of HSPB2, a member of the small heat shock protein family, with mitochondria. Exp Cell Res (2001) 1.00
Binding of the stress protein alpha B-crystallin to cardiac myofibrils correlates with the degree of myocardial damage during ischemia/reperfusion in vivo. J Mol Cell Cardiol (1999) 1.00
Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T. Cardiovasc Res (2008) 1.00
Increased expression of HSP27 protects canine myocytes from simulated ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol (2002) 1.00
HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes. PLoS One (2011) 1.00
Ischemia-induced increase of stiffness of alphaB-crystallin/HSPB2-deficient myocardium. Pflugers Arch (2005) 1.00
Localization, macromolecular associations, and function of the small heat shock-related protein HSP20 in rat heart. Circulation (2003) 0.99
Aging skeletal muscle shows a drastic increase in the small heat shock proteins alphaB-crystallin/HspB5 and cvHsp/HspB7. Eur J Cell Biol (2007) 0.99
Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling. Circ Res (2011) 0.98
Association of high intracellular, but not serum, heat shock protein 70 with postoperative atrial fibrillation. Ann Thorac Surg (2005) 0.98
Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression. J Biol Chem (2007) 0.98
Effects of a heat shock protein inducer on the atrial fibrillation substrate caused by acute atrial ischaemia. Cardiovasc Res (2008) 0.98
Suppression of NF-kappaB activation by Entamoeba histolytica in intestinal epithelial cells is mediated by heat shock protein 27. J Biol Chem (2006) 0.98
Low preoperative HSP70 atrial myocardial levels correlate significantly with high incidence of postoperative atrial fibrillation after cardiac surgery. Cardiovasc Surg (2002) 0.97
Abundance and location of the small heat shock proteins HSP25 and alphaB-crystallin in rat and human heart. Circulation (1997) 0.96
Repetitive 4-week periods of atrial electrical remodeling promote stability of atrial fibrillation: time course of a second factor involved in the self-perpetuation of atrial fibrillation. Circulation (2004) 0.96
Proteasome activation during cardiac hypertrophy by the chaperone H11 Kinase/Hsp22. Cardiovasc Res (2007) 0.96
CRYAB and HSPB2 deficiency increases myocyte mitochondrial permeability transition and mitochondrial calcium uptake. J Mol Cell Cardiol (2006) 0.96
Adaptation of the rat cardiac proteome in response to intensity-controlled endurance exercise. Proteomics (2009) 0.96
HSPB7 is a SC35 speckle resident small heat shock protein. Biochim Biophys Acta (2009) 0.95
alpha B-crystallin and hsp25 in neonatal cardiac cells--differences in cellular localization under stress conditions. Eur J Cell Biol (1998) 0.95
Expression of small heat shock proteins HspB2, HspB8, Hsp20 and cvHsp in different tissues of the perinatal developing pig. Eur J Cell Biol (2003) 0.95
Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects. J Biol Chem (2008) 0.94
Electrophysiological correlation and prognostic impact of heat shock protein 27 in atrial fibrillation. Circ Arrhythm Electrophysiol (2012) 0.90
Calpain mediates cardiac troponin degradation and contractile dysfunction in atrial fibrillation. J Mol Cell Cardiol (2008) 0.90
Exercise training affects age-induced changes in SOD and heat shock protein expression in rat heart. Exp Gerontol (2006) 0.89
Importance of small heat shock protein 20 (hsp20) C-terminal extension in cardioprotection. J Mol Cell Cardiol (2007) 0.89
Translocation of HSP27 and MKBP in ischemic heart. Cell Struct Funct (1999) 0.89
Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation. J Mol Cell Cardiol (2011) 0.89
Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation. Circulation (2013) 0.88
Interactive domains in the molecular chaperone human alphaB crystallin modulate microtubule assembly and disassembly. PLoS One (2007) 0.87
Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins. J Cell Biol (2014) 0.86
Small heat shock proteins, protein degradation and protein aggregation diseases. Autophagy (2011) 0.86
Heat shock protein-inducing compounds as therapeutics to restore proteostasis in atrial fibrillation. Trends Cardiovasc Med (2012) 0.84
Preemptive conditioning of the swine heart by H11 kinase/Hsp22 provides cardiac protection through inducible nitric oxide synthase. Am J Physiol Heart Circ Physiol (2011) 0.84
Expression of mortalin in patients with chronic atrial fibrillation. Basic Res Cardiol (2004) 0.83
HSPB2 is dispensable for the cardiac hypertrophic response but reduces mitochondrial energetics following pressure overload in mice. PLoS One (2012) 0.82
The molecular chaperone hsp70 interacts with the cytosolic II-III loop of the Cav2.3 E-type voltage-gated Ca2+ channel. Cell Physiol Biochem (2006) 0.81
Overexpression of heat shock protein 60/10 in myocardium of patients with chronic atrial fibrillation. Ann Thorac Surg (2002) 0.81
Fractionation of electrograms is caused by colocalized conduction block and connexin disorganization in the absence of fibrosis as AF becomes persistent in the goat model. Heart Rhythm (2014) 0.80
Heat shock proteins as potential targets for protective strategies in neurodegeneration. Lancet Neurol (2016) 0.79
HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles. J Cell Sci (2016) 0.79
HSP25 can modulate myofibrillar desmin cytoskeleton following the phosphorylation at Ser15 in rat soleus muscle. J Appl Physiol (1985) (2011) 0.78
Targeting the molecular mechanisms of ischemic damage: Protective effects of alpha-crystallin-B. Int J Cardiol (2016) 0.76
Impact of leucine supplementation on exercise training induced anti-cardiac remodeling effect in heart failure mice. Nutrients (2015) 0.76
Heat shock protein modulation of KATP and KCa channel cerebrovasodilation after brain injury. Am J Physiol Heart Circ Physiol (2005) 0.76