Published in Mol Cell on May 06, 2011
Replicative and chronological aging in Saccharomyces cerevisiae. Cell Metab (2012) 2.56
The retrograde response: when mitochondrial quality control is not enough. Biochim Biophys Acta (2012) 1.18
The yeast retrograde response as a model of intracellular signaling of mitochondrial dysfunction. Front Physiol (2012) 1.14
A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metab (2015) 1.05
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer. Genes Dev (2012) 1.04
Mitonuclear communication in homeostasis and stress. Nat Rev Mol Cell Biol (2016) 1.01
Loss of mitochondrial membrane potential triggers the retrograde response extending yeast replicative lifespan. Front Genet (2012) 1.00
The good and the bad of being connected: the integrons of aging. Curr Opin Cell Biol (2013) 0.94
Mitochondrial stress signaling in longevity: a new role for mitochondrial function in aging. Redox Biol (2014) 0.93
Diet-related telomere shortening and chromosome stability. Mutagenesis (2011) 0.92
Yeast sirtuins and the regulation of aging. FEMS Yeast Res (2013) 0.92
Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging. Genome Biol (2015) 0.89
The retrograde response: a conserved compensatory reaction to damage from within and from without. Prog Mol Biol Transl Sci (2014) 0.88
Mechanisms by which different functional states of mitochondria define yeast longevity. Int J Mol Sci (2015) 0.87
Adenine nucleotide translocase, mitochondrial stress, and degenerative cell death. Oxid Med Cell Longev (2013) 0.87
Quasi-programmed aging of budding yeast: a trade-off between programmed processes of cell proliferation, differentiation, stress response, survival and death defines yeast lifespan. Cell Cycle (2014) 0.83
Dietary restriction, mitochondrial function and aging: from yeast to humans. Biochim Biophys Acta (2015) 0.83
Mitochondrial translation initiation machinery: conservation and diversification. Biochimie (2013) 0.80
Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes. Oxid Med Cell Longev (2015) 0.79
The search for nonconventional mitochondrial determinants of aging. Mol Cell (2011) 0.76
Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science (2003) 4.71
ppGpp: a global regulator in Escherichia coli. Trends Microbiol (2005) 3.51
The polarisome is required for segregation and retrograde transport of protein aggregates. Cell (2010) 3.13
Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli. Mol Cell (2013) 2.65
The bacterial universal stress protein: function and regulation. Curr Opin Microbiol (2003) 2.54
Revealing the genetic structure of a trait by sequencing a population under selection. Genome Res (2011) 2.42
Regulation of sigma factor competition by the alarmone ppGpp. Genes Dev (2002) 2.36
Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p. Genes Dev (2007) 2.32
Differential roles of the universal stress proteins of Escherichia coli in oxidative stress resistance, adhesion, and motility. J Bacteriol (2005) 2.01
Identical, independent, and opposing roles of ppGpp and DksA in Escherichia coli. J Bacteriol (2007) 1.86
Genomic buffering mitigates the effects of deleterious mutations in bacteria. Nat Genet (2005) 1.79
Life span extension and H(2)O(2) resistance elicited by caloric restriction require the peroxiredoxin Tsa1 in Saccharomyces cerevisiae. Mol Cell (2011) 1.71
Biogenesis of Fe-S cluster by the bacterial Suf system: SufS and SufE form a new type of cysteine desulfurase. J Biol Chem (2003) 1.63
Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice. Proc Natl Acad Sci U S A (2010) 1.56
Differential oxidative damage and expression of stress defence regulons in culturable and non-culturable Escherichia coli cells. EMBO Rep (2003) 1.51
Inflammation and the etiology of type 2 diabetes. Diabetes Metab Res Rev (2005) 1.49
Endothelial inflammation in insulin resistance. Lancet (2005) 1.46
Progression and specificity of protein oxidation in the life cycle of Arabidopsis thaliana. J Biol Chem (2004) 1.46
Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2007) 1.43
Pronounced elevation of resistin correlates with severity of disease in severe sepsis and septic shock. Crit Care Med (2007) 1.39
Elimination of damaged proteins during differentiation of embryonic stem cells. Proc Natl Acad Sci U S A (2006) 1.36
Limiting factors in Escherichia coli fed-batch production of recombinant proteins. Biotechnol Bioeng (2003) 1.31
The oncogenic RAS2(val19) mutation locks respiration, independently of PKA, in a mode prone to generate ROS. EMBO J (2003) 1.28
The role of the alarmone (p)ppGpp in sigma N competition for core RNA polymerase. J Biol Chem (2002) 1.28
SufA from Erwinia chrysanthemi. Characterization of a scaffold protein required for iron-sulfur cluster assembly. J Biol Chem (2003) 1.24
Defense against protein carbonylation by DnaK/DnaJ and proteases of the heat shock regulon. J Bacteriol (2005) 1.15
The DPP-4 inhibitor linagliptin counteracts stroke in the normal and diabetic mouse brain: a comparison with glimepiride. Diabetes (2012) 1.13
Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. Genes Dev (2007) 1.11
Heat shock protein-mediated resistance to high hydrostatic pressure in Escherichia coli. Appl Environ Microbiol (2004) 1.10
Inactivation of the Pseudomonas putida cytochrome o ubiquinol oxidase leads to a significant change in the transcriptome and to increased expression of the CIO and cbb3-1 terminal oxidases. Environ Microbiol (2006) 1.06
Peroxiredoxins, gerontogenes linking aging to genome instability and cancer. Genes Dev (2012) 1.04
A microfluidic system in combination with optical tweezers for analyzing rapid and reversible cytological alterations in single cells upon environmental changes. Lab Chip (2006) 1.03
Increased RNA polymerase availability directs resources towards growth at the expense of maintenance. EMBO J (2009) 1.01
Chemogenetic fingerprinting by analysis of cellular growth dynamics. BMC Chem Biol (2008) 0.98
A simple intravenous glucose tolerance test for assessment of insulin sensitivity. Theor Biol Med Model (2011) 0.97
Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, p38 MAPK, and JNK pathways. J Mol Endocrinol (2013) 0.97
Induction of the heat shock regulon in response to increased mistranslation requires oxidative modification of the malformed proteins. Mol Microbiol (2006) 0.97
Insulin sensitivity and lipid profile in prolactinoma patients before and after normalization of prolactin by dopamine agonist therapy. Pituitary (2011) 0.97
Conditional and replicative senescence in Escherichia coli. Curr Opin Microbiol (2006) 0.96
Segregation of protein aggregates involves actin and the polarity machinery. Cell (2011) 0.96
Metabolic control of the Escherichia coli universal stress protein response through fructose-6-phosphate. Mol Microbiol (2007) 0.95
Elevated Ras/protein kinase A activity in Saccharomyces cerevisiae reduces proliferation rate and lifespan by two different reactive oxygen species-dependent routes. Aging Cell (2007) 0.94
Enhancing protein disaggregation restores proteasome activity in aged cells. Aging (Albany NY) (2013) 0.92
Mediator influences telomeric silencing and cellular life span. Mol Cell Biol (2011) 0.92
Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance. EMBO J (2014) 0.91
Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans. Am J Clin Nutr (2014) 0.91
Early signs of atherosclerosis are associated with insulin resistance in non-obese adolescent and young adults with type 1 diabetes. Cardiovasc Diabetol (2012) 0.91
Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster. Aging Cell (2012) 0.90
H2O2 activates the nuclear localization of Msn2 and Maf1 through thioredoxins in Saccharomyces cerevisiae. Eukaryot Cell (2009) 0.90
Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28. Sci Rep (2013) 0.89
Mediator promotes CENP-a incorporation at fission yeast centromeres. Mol Cell Biol (2012) 0.89
Effects of some anti-diabetic and cardioprotective agents on proliferation and apoptosis of human coronary artery endothelial cells. Cardiovasc Diabetol (2012) 0.89
Endothelial dysfunction induced by triglycerides is not restored by exenatide in rat conduit arteries ex vivo. Regul Pept (2009) 0.89
Sir2-dependent asymmetric segregation of damaged proteins in ubp10 null mutants is independent of genomic silencing. Biochim Biophys Acta (2010) 0.89
Cardiorespiratory fitness predicts insulin action and secretion in healthy individuals. Metabolism (2011) 0.87
Hypoglycemic pharmacological treatment of type 2 diabetes: targeting the endothelium. Mol Cell Endocrinol (2008) 0.87
The role of mitochondria in the aging processes of yeast. Subcell Biochem (2012) 0.86
Protein quality control in time and space - links to cellular aging. FEMS Yeast Res (2013) 0.84
A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DksA protein during the stringent response. J Biol Chem (2013) 0.84
LHON/MELAS overlap mutation in ND1 subunit of mitochondrial complex I affects ubiquinone binding as revealed by modeling in Escherichia coli NDH-1. Biochim Biophys Acta (2011) 0.83
Fed-batch production of recombinant beta-galactosidase using the universal stress promoters uspA and uspB in high cell density cultivations. Biotechnol Bioeng (2003) 0.83
Heterodimer formation within universal stress protein classes revealed by an in silico and experimental approach. J Mol Biol (2008) 0.82
Evaluation of inducible promoters on the secretion of a ZZ-proinsulin fusion protein in Escherichia coli. Biotechnol Appl Biochem (2003) 0.82
Plasma volume expansion resulting from intravenous glucose tolerance test. Comput Math Methods Med (2011) 0.81
Intravenous hydration with a 2.5% glucose solution in Type II diabetes. Clin Sci (Lond) (2006) 0.81
Analysis of molecular diffusion in ftsK cell-division mutants using laser surgery. EMBO Rep (2003) 0.81
Glucagon-Like Peptide-1 Receptor Activation Does not Affect Re-Endothelialization but Reduces Intimal Hyperplasia via Direct Effects on Smooth Muscle Cells in a Nondiabetic Model of Arterial Injury. J Vasc Res (2015) 0.81
Accuracy and precision of commonly used methods for quantifying surgery-induced insulin resistance: Prospective observational study. Eur J Anaesthesiol (2014) 0.80
The yeast transcription factor Crz1 is activated by light in a Ca2+/calcineurin-dependent and PKA-independent manner. PLoS One (2013) 0.80
Metagenomics reveals that detoxification systems are underrepresented in marine bacterial communities. BMC Genomics (2014) 0.79
[Chronic inflammation can cause type 2 diabetes]. Lakartidningen (2004) 0.78
Cloning of two cellobiohydrolase genes from Trichoderma viride and heterogeneous expression in yeast Saccharomyces cerevisiae. Mol Biol Rep (2009) 0.78
Function of a novel cadmium-induced yodA protein in Escherichia coli. Curr Microbiol (2007) 0.78
Plasma volume expansion from the intravenous glucose tolerance test before and after hip replacement surgery. Theor Biol Med Model (2013) 0.78
The potent vasodilator ethyl nitrite is formed upon reaction of nitrite and ethanol under gastric conditions. Free Radic Biol Med (2008) 0.77
The Escherichia coli ftsK1 mutation attenuates the induction of sigma(S)-dependent genes upon transition to stationary phase. FEMS Microbiol Lett (2002) 0.77
Perspectives on the mitochondrial etiology of replicative aging in yeast. Exp Gerontol (2010) 0.77
GLP-1R activation for the treatment of stroke: updating and future perspectives. Rev Endocr Metab Disord (2014) 0.77
Exendin-4 restores glucolipotoxicity-induced gene expression in human coronary artery endothelial cells. Biochem Biophys Res Commun (2012) 0.77
Evidence for paracrine/autocrine regulation of GLP-1-producing cells. Am J Physiol Cell Physiol (2013) 0.76
The dual role of a yeast metacaspase: What doesn't kill you makes you stronger. Bioessays (2015) 0.76
Suppressor of cytokine signaling 2 (SOCS2) deletion protects against multiple low dose streptozotocin-induced type 1 diabetes in adult male mice. Horm Mol Biol Clin Investig (2016) 0.75
Reply: Association of Glycemic Control in Type 1 Diabetes With Long-Term Risk After CABG. J Am Coll Cardiol (2015) 0.75
[Glycerol kinase deficiency with debut of symptoms in adult age. Unusual cause of coma, metabolic acidosis, hypoglycemia and hypothermia]. Lakartidningen (2010) 0.75
The impact of transcutaneous oxygen pressure measurement in patients with suspected critical lower limb ischemia. Int Angiol (2015) 0.75
Intensified insulin treatment is associated with improvement in skin microcirculation and ischaemic foot ulcer in patients with type 1 diabetes mellitus: a long-term follow-up study. Diabetologia (2014) 0.75
Acute regulation of pancreatic islet microcirculation and glycaemia by telmisartan and ramipril: discordant effects between normal and type 2 diabetic rats. Clin Sci (Lond) (2013) 0.75