Bim protein degradation contributes to cisplatin resistance.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 3121386)

Published in J Biol Chem on May 11, 2011

Authors

Juan Wang1, Jun-Ying Zhou, Gen Sheng Wu

Author Affiliations

1: Program in Molecular Biology and Genetics, Karmanos Cancer Institute, Departments of Oncology and Pathology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

Articles citing this

Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates. Sci Transl Med (2014) 1.09

Role of autophagy in cisplatin resistance in ovarian cancer cells. J Biol Chem (2014) 1.09

Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin. J Biol Chem (2012) 0.90

Improving but inferior survival in patients with chronic lymphocytic leukemia in taiwan: a population-based study, 1990-2004. PLoS One (2013) 0.84

The role of DAPK-BimEL pathway in neuronal death induced by oxygen-glucose deprivation. Neuroscience (2013) 0.82

Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability. Oncogene (2015) 0.81

Eribulin mesylate targets human telomerase reverse transcriptase in ovarian cancer cells. PLoS One (2014) 0.81

Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a. Int J Mol Med (2015) 0.80

Downregulation of miR-17~92 Expression Increase Paclitaxel Sensitivity in Human Ovarian Carcinoma SKOV3-TR30 Cells via BIM Instead of PTEN. Int J Mol Sci (2013) 0.79

High Prevalence of the BIM Deletion Polymorphism in Young Female Breast Cancer in an East Asian Country. PLoS One (2015) 0.77

Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells. Oncotarget (2016) 0.76

Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors. Sci Rep (2017) 0.75

ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer. Neoplasia (2017) 0.75

Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway. Cell Death Dis (2016) 0.75

Caspase 8 expression may determine the survival of women with ovarian cancer. Cell Death Dis (2016) 0.75

API5 induces cisplatin resistance through FGFR signaling in human cancer cells. Exp Mol Med (2017) 0.75

Impact of the Bim Deletion Polymorphism on Survival Among Patients With Completely Resected Non-Small-Cell Lung Carcinoma. J Glob Oncol (2015) 0.75

Articles cited by this

Mammalian MAP kinase signalling cascades. Nature (2001) 18.89

The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer (2002) 14.94

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science (2002) 14.50

The resurgence of platinum-based cancer chemotherapy. Nat Rev Cancer (2007) 12.38

Cellular processing of platinum anticancer drugs. Nat Rev Drug Discov (2005) 9.47

Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J (1998) 7.17

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A (2003) 5.01

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem (2003) 4.55

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet (1997) 4.46

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function. Oncogene (2003) 3.96

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. Cancer Cell (2005) 3.19

Regulatory phosphorylation of Bim: sorting out the ERK from the JNK. Cell Death Differ (2005) 3.00

AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth. Oncogene (2004) 2.67

Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover. J Biol Chem (2003) 2.31

Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J Biol Chem (2005) 2.27

Messenger RNA levels of XPAC and ERCC1 in ovarian cancer tissue correlate with response to platinum-based chemotherapy. J Clin Invest (1994) 1.97

The roles of copper transporters in cisplatin resistance. Cancer Metastasis Rev (2007) 1.96

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL. EMBO J (2007) 1.90

Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res (1996) 1.85

Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells. Cell Cycle (2009) 1.80

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways. Oncogene (2003) 1.76

p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65. J Biol Chem (2006) 1.64

ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res (2007) 1.52

BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members. Mol Endocrinol (1998) 1.38

Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells. Biochem Biophys Res Commun (2010) 1.37

Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res (2006) 1.35

Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer. Cancer Metastasis Rev (2007) 1.29

The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death. Cancer Res (2006) 1.23

Glutathione S-transferase pi amplification is associated with cisplatin resistance in head and neck squamous cell carcinoma cell lines and primary tumors. Cancer Res (2003) 1.18

BCL-2 family protein expression and platinum drug resistance in ovarian carcinoma. Br J Cancer (2000) 1.15

MEK1/2 inhibitors potentiate UCN-01 lethality in human multiple myeloma cells through a Bim-dependent mechanism. Blood (2007) 1.10

Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Res (2007) 1.06

Cross-resistance, cisplatin accumulation, and platinum-DNA adduct formation and removal in cisplatin-sensitive and -resistant human hepatoma cell lines. Exp Cell Res (1996) 0.98

The role of neoadjuvant chemotherapy in treating advanced epithelial ovarian cancer. J Surg Oncol (2010) 0.96

Nitric oxide and cisplatin resistance: NO easy answers. Proc Natl Acad Sci U S A (2006) 0.91

Articles by these authors

Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects. Sci Transl Med (2013) 2.06

Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells. Cell Cycle (2009) 1.80

DR5 knockout mice are compromised in radiation-induced apoptosis. Mol Cell Biol (2005) 1.55

ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res (2007) 1.52

Stochastic cancer progression driven by non-clonal chromosome aberrations. J Cell Physiol (2006) 1.37

Role of the Akt/mTOR survival pathway in cisplatin resistance in ovarian cancer cells. Biochem Biophys Res Commun (2010) 1.37

Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res (2006) 1.35

TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death. Cancer Biol Ther (2008) 1.34

The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death. Cancer Res (2006) 1.23

The phosphatase MKP1 is a transcriptional target of p53 involved in cell cycle regulation. J Biol Chem (2003) 1.20

Cisplatin resistance associated with PARP hyperactivation. Cancer Res (2013) 1.11

The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment. Cancer Metastasis Rev (2010) 1.09

Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death. Cancer Biol Ther (2008) 1.08

Activation of the Akt survival pathway contributes to TRAIL resistance in cancer cells. PLoS One (2010) 1.08

Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin. Cancer Res (2007) 1.06

Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells. Mol Cancer Ther (2002) 1.04

Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study. Cancer Res (2008) 0.98

Sp1-mediated TRAIL induction in chemosensitization. Cancer Res (2008) 0.94

Mitogen activated protein kinase phosphatases and cancer. Cancer Biol Ther (2010) 0.93

Induction of apoptosis by the new anticancer drug XK469 in human ovarian cancer cell lines. Oncogene (2002) 0.92

Post-translational regulation of mitogen-activated protein kinase phosphatase-2 (MKP-2) by ERK. Cell Cycle (2010) 0.92

Mitotic cell death by chromosome fragmentation. Cancer Res (2007) 0.91

Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy. Cancer Res (2006) 0.86

Improved efficacy by individualized combination therapy with Peg IFN-a 2a and ADV in HBeAg positive chronic hepatitis B patients. Hepatogastroenterology (2012) 0.84

Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J Biol Chem (2013) 0.83

p53 Transactivates the phosphatase MKP1 through both intronic and exonic p53 responsive elements. Cancer Biol Ther (2004) 0.83

[Relationship between excessive daytime sleepiness and oxygen saturation in obstructive sleep apnea-hypopnea syndrome]. Zhonghua Yi Xue Za Zhi (2011) 0.82

Cullin-3 protein expression levels correlate with breast cancer progression. Cancer Biol Ther (2012) 0.81

Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity. Oncotarget (2014) 0.80

The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling. Cell Cycle (2014) 0.79

High level of mitogen-activated protein kinase phosphatase-1 expression is associated with cisplatin resistance in osteosarcoma. Pediatr Blood Cancer (2008) 0.79

[Molecular mechanism of ciglitazone inhibiting the expression of extracellular matrix in human hepatic stellate cells]. Zhonghua Gan Zang Bing Za Zhi (2007) 0.78

Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer: A systematic review and meta-analysis. Medicine (Baltimore) (2016) 0.78

Induction of proapoptotic antibodies to triple-negative breast cancer by vaccination with TRAIL death receptor DR5 DNA. Int J Cancer (2012) 0.75

[Effect of microbial pharmaceutics on the function of NKT cells in rats with non-alcoholic steatohepatitis]. Zhonghua Gan Zang Bing Za Zhi (2011) 0.75

[Severe intrahepatic cholestasis and hemochromatosis secondary to hereditary spherocytosis]. Zhonghua Gan Zang Bing Za Zhi (2010) 0.75