Published in Blood on May 11, 2011
Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model. J Exp Med (2014) 1.59
Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency. Blood (2014) 1.45
Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation. J Immunol (2014) 1.24
Chronic inflammation and aging: DNA damage tips the balance. Curr Opin Immunol (2012) 1.13
Regulatory functions of innate-like B cells. Cell Mol Immunol (2013) 1.10
Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus. Proc Natl Acad Sci U S A (2013) 1.10
Identification of IFN-γ-producing innate B cells. Cell Res (2013) 1.10
A molecular mechanism for TNF-α-mediated downregulation of B cell responses. J Immunol (2011) 1.10
T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance. Proc Natl Acad Sci U S A (2013) 1.08
Anti-IFN-α/β receptor antibody treatment ameliorates disease in lupus-predisposed mice. J Immunol (2012) 1.03
Revisiting the B-cell compartment in mouse and humans: more than one B-cell subset exists in the marginal zone and beyond. BMC Immunol (2012) 1.01
In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors. Aging Cell (2013) 0.97
Role of nucleic acid-sensing TLRs in diverse autoantibody specificities and anti-nuclear antibody-producing B cells. J Immunol (2013) 0.95
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Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis. Aging Cell (2014) 0.92
TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice. Immunol Res (2013) 0.92
Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proc Natl Acad Sci U S A (2012) 0.91
A comparative review of aging and B cell function in mice and humans. Curr Opin Immunol (2013) 0.90
Sexual dimorphism in autoimmunity. J Clin Invest (2015) 0.87
CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs. J Immunol (2015) 0.87
Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice. Int Immunol (2014) 0.84
Aging impairs murine B cell differentiation and function in primary and secondary lymphoid tissues. Aging Dis (2011) 0.84
Hepatitis C viremia reversibly maintains subset of antigen-specific T-bet+ tissue-like memory B-cells. J Viral Hepat (2016) 0.84
Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. JCI Insight (2016) 0.84
Potential importance of B cells in aging and aging-associated neurodegenerative diseases. Semin Immunopathol (2017) 0.83
B cells expressing the transcription factor T-bet drive lupus-like autoimmunity. J Clin Invest (2017) 0.83
B cell infection and activation by rabies virus-based vaccines. J Virol (2013) 0.82
T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. JCI Insight (2017) 0.82
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Aging and neoteny in the B lineage. Blood (2012) 0.81
Aging and the immune response to organ transplantation. J Clin Invest (2017) 0.80
Accumulation of 4-1BBL+ B cells in the elderly induces the generation of granzyme-B+ CD8+ T cells with potential antitumor activity. Blood (2014) 0.80
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Pivotal Functions of Plasmacytoid Dendritic Cells in Systemic Autoimmune Pathogenesis. J Clin Cell Immunol (2014) 0.79
Impaired B lymphopoiesis in old age: a role for inflammatory B cells? Immunol Res (2013) 0.79
In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells. Aging Cell (2015) 0.78
Aged B cells alter immune regulation of allografts in mice. Eur J Immunol (2016) 0.76
B cells in the aging immune system: time to consider B-1 cells. Ann N Y Acad Sci (2015) 0.76
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Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation. J Immunol (2017) 0.76
Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol (2016) 0.76
Nodal marginal zone B cells in mice: a novel subset with dormant self-reactivity. Sci Rep (2016) 0.76
Immunosenescence in renal transplantation: a changing balance of innate and adaptive immunity. Curr Opin Organ Transplant (2015) 0.75
Uncoupling of natural IgE production and CD23 surface expression levels. PLoS One (2013) 0.75
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Plasmodium chabaudi infection induces AID expression in transitional and marginal zone B cells. Immun Inflamm Dis (2016) 0.75
CD21(-/low) B cells in human blood are memory cells. Clin Exp Immunol (2016) 0.75
Ageing adversely affects the migration and function of marginal zone B cells. Immunology (2017) 0.75
Obesity induces pro-inflammatory B cells and impairs B cell function in old mice. Mech Ageing Dev (2017) 0.75
Early derivation of IgM memory cells and bone marrow plasmablasts. PLoS One (2017) 0.75
Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses. Cell Death Dis (2017) 0.75
Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later. Periodontol 2000 (2017) 0.75
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature (2006) 20.00
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J Virol (2003) 11.48
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature (2002) 11.05
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol (2008) 10.26
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med (2008) 5.14
T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity (2009) 4.69
Identification of a B-1 B cell-specified progenitor. Nat Immunol (2006) 4.52
A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection. Immunity (2009) 3.66
Effector and regulatory B cells: modulators of CD4+ T cell immunity. Nat Rev Immunol (2010) 3.56
Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood (2010) 3.52
T-cell exhaustion: characteristics, causes and conversion. Immunology (2010) 2.24
Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses. J Exp Med (2004) 2.23
The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors. J Immunol (2003) 2.17
Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol (2002) 2.16
The immune system in extreme longevity. Exp Gerontol (2007) 2.15
B-cell diversity decreases in old age and is correlated with poor health status. Aging Cell (2008) 2.15
Immunosenescence and germinal center reaction. Immunol Rev (1997) 2.00
Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Annu Rev Immunol (2000) 1.95
CD4 T cell memory derived from young naive cells functions well into old age, but memory generated from aged naive cells functions poorly. Proc Natl Acad Sci U S A (2003) 1.89
BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. Proc Natl Acad Sci U S A (2008) 1.88
CD4+CD25+Foxp3+ T cells and CD4+CD25-Foxp3+ T cells in aged mice. J Immunol (2006) 1.83
Signals that influence T follicular helper cell differentiation and function. Semin Immunopathol (2010) 1.62
TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells. J Immunol (2007) 1.56
T-cell immunosenescence: lessons learned from mouse models of aging. Trends Immunol (2009) 1.55
Space, selection, and surveillance: setting boundaries with BLyS. J Immunol (2006) 1.55
Clonal expansions and loss of receptor diversity in the naive CD8 T cell repertoire of aged mice. J Immunol (2009) 1.53
Aging and developmental transitions in the B cell lineage. Int Immunol (2002) 1.40
B cells and aging: molecules and mechanisms. Trends Immunol (2009) 1.38
Censoring of autoreactive B cell development by the pre-B cell receptor. Science (2008) 1.35
Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice. J Exp Med (2004) 1.34
Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging. Proc Natl Acad Sci U S A (2008) 1.25
Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells. J Exp Med (2002) 1.24
Effects of aging on B cell function. Curr Opin Immunol (2009) 1.24
The BLyS family: toward a molecular understanding of B cell homeostasis. Cell Biochem Biophys (2008) 1.23
A double-negative (IgD-CD27-) B cell population is increased in the peripheral blood of elderly people. Mech Ageing Dev (2009) 1.21
Convergence of CpG DNA- and BCR-mediated signals at the c-Jun N-terminal kinase and NF-kappaB activation pathways: regulation by mitogen-activated protein kinases. Int Immunol (2003) 1.14
Transcription factor regulation of CD8+ T-cell memory and exhaustion. Immunol Rev (2010) 1.08
Cutting edge: Complement (C3d)-linked antigens break B cell anergy. J Immunol (2007) 1.05
Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age. Aging Cell (2010) 1.02
Immune receptor signaling, aging, and autoimmunity. Cell Immunol (2005) 1.01
B cells and immunosenescence: a focus on IgG+IgD-CD27- (DN) B cells in aged humans. Ageing Res Rev (2010) 0.98
B cell receptor cross-talk: exposure to lipopolysaccharide induces an alternate pathway for B cell receptor-induced ERK phosphorylation and NF-kappa B activation. J Immunol (2007) 0.96
Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice. Cell Immunol (2003) 0.96
Potentiation of Th17 cytokines in aging process contributes to the development of colitis. Cell Immunol (2010) 0.96
The Bw cells, a novel B cell population conserved in the whole genus Mus. J Immunol (2007) 0.93
A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1. Immunogenetics (2002) 0.92
Effect of age on the immunoglobulin class switch. Crit Rev Immunol (2004) 0.88
Differential B cell expression of mouse Fc receptor homologs. Int Immunol (2004) 0.87
The effect of age on B cell development and humoral immunity. Springer Semin Immunopathol (2002) 0.86
Increase of cross(auto)-reactive antibodies after immunization in aged mice: a cellular and molecular study. Int J Exp Pathol (1994) 0.83
Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling. Science (2003) 2.46
Dispensability of APRIL to the development of systemic lupus erythematosus in NZM 2328 mice. Arthritis Rheum (2012) 2.21
Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol (2002) 2.16
Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling. Nat Immunol (2008) 1.96
BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. Proc Natl Acad Sci U S A (2008) 1.88
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol (2011) 1.84
TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells. J Immunol (2007) 1.56
Space, selection, and surveillance: setting boundaries with BLyS. J Immunol (2006) 1.55
A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol (2010) 1.44
Cutting edge: B cell receptor signals regulate BLyS receptor levels in mature B cells and their immediate progenitors. J Immunol (2003) 1.42
B cells and aging: molecules and mechanisms. Trends Immunol (2009) 1.38
Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice. J Exp Med (2004) 1.34
B cell maintenance and function in aging. Semin Immunol (2012) 1.25
The BLyS family: toward a molecular understanding of B cell homeostasis. Cell Biochem Biophys (2008) 1.23
BAFF and the plasticity of peripheral B cell tolerance. Curr Opin Immunol (2008) 1.20
The role of BLyS/BLyS receptors in anti-chromatin B cell regulation. Int Immunol (2007) 1.18
In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice. J Immunol (2008) 1.14
Role of type I interferons in the activation of autoreactive B cells. Immunol Cell Biol (2012) 1.10
Asymmetric B cell division in the germinal center reaction. Science (2011) 1.10
Mutagenicity and potential carcinogenicity of thiopurine treatment in patients with inflammatory bowel disease. Cancer Res (2009) 1.09
Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. J Exp Med (2013) 1.06
BLyS receptor signatures resolve homeostatically independent compartments among naïve and antigen-experienced B cells. Semin Immunol (2006) 1.06
Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI. J Clin Invest (2011) 1.01
Targeting BLyS in rheumatic disease: the sometimes-bumpy road from bench to bedside. Curr Opin Rheumatol (2011) 0.99
Homeostatic niche specification among naïve and activated B cells: a growing role for the BLyS family of receptors and ligands. Semin Immunol (2005) 0.99
Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells. J Biol Chem (2009) 0.98
Travelling with the BAFF/BLyS family: are we there yet? Semin Immunol (2006) 0.97
Cutting edge: impaired transitional B cell production and selection in the nonobese diabetic mouse. J Immunol (2006) 0.97
Long-lived bone marrow plasma cells are induced early in response to T cell-independent or T cell-dependent antigens. J Immunol (2012) 0.97
Secondary cleft sign as a marker of injury in athletes with groin pain: MR image appearance and interpretation. Radiology (2005) 0.95
BLyS-mediated modulation of naive B cell subsets impacts HIV Env-induced antibody responses. J Immunol (2012) 0.93
FcgammaRIIB signals inhibit BLyS signaling and BCR-mediated BLyS receptor up-regulation. Blood (2008) 0.93
B cells and aging: balancing the homeostatic equation. Exp Gerontol (2007) 0.93
Homeostatic control of B lymphocyte subsets. Immunol Res (2008) 0.92
A comparative review of aging and B cell function in mice and humans. Curr Opin Immunol (2013) 0.90
Role of beta-catenin in B cell development and function. J Immunol (2008) 0.89
Development of systemic lupus erythematosus in NZM 2328 mice in the absence of any single BAFF receptor. Arthritis Rheum (2013) 0.87
Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustment. Immunol Lett (2012) 0.86
Murine islet allograft tolerance upon blockade of the B-lymphocyte stimulator, BLyS/BAFF. Transplantation (2012) 0.86
Relationships between self-assessment skills, test performance, and demographic variables in psychiatry residents. Adv Health Sci Educ Theory Pract (2006) 0.86
Chronic spinal cord injury impairs primary antibody responses but spares existing humoral immunity in mice. J Immunol (2012) 0.86
Screening of alternative models for transitional B cell maturation. Int Immunol (2004) 0.86
Distinct conformations of DNA-stabilized fluorescent silver nanoclusters revealed by electrophoretic mobility and diffusivity measurements. Langmuir (2011) 0.85
Repair of giant abdominal hernias: does the type of prosthesis matter? Am Surg (2004) 0.83
Acquisition of humoral transplantation tolerance upon de novo emergence of B lymphocytes. J Immunol (2010) 0.83
Decompressive craniectomy or medical management for refractory intracranial hypertension: an AAST-MIT propensity score analysis. J Trauma Acute Care Surg (2014) 0.82
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Global T cell dysregulation in non-autoimmune-prone mice promotes rapid development of BAFF-independent, systemic lupus erythematosus-like autoimmunity. J Immunol (2008) 0.79
Ethical decision-making and the Code of Ethics of the Canadian Psychological Association. Can Psychol (1996) 0.79
Exploring human/animal intersections: converging lines of evidence in comparative models of aging. Alzheimers Dement (2007) 0.79
B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation. Transplant Rev (Orlando) (2010) 0.79
Connecting the dots: revealing the interactions of lymphocyte development and homeostasis in the immunobiology of aging. Semin Immunol (2005) 0.78
Dwindling competition with constant demand: can homeostatic adjustments explain age-associated changes in peripheral B cell selection? Semin Immunol (2005) 0.78
Kinetic modeling reveals a common death niche for newly formed and mature B cells. PLoS One (2010) 0.78
Editorial: phagocytic B cells: déjà vu all over again? J Leukoc Biol (2012) 0.77
BLyS: the pivotal determinant of peripheral B cell selection and lifespan. Curr Pharm Des (2003) 0.77
Unraveling the warp and weft of B cell fate. Immunity (2006) 0.76
pERKing up the BLIMP in plasma cell differentiation. Sci Signal (2011) 0.76
Calcaneal reconstruction with free fibular osteocutaneous flap. J Reconstr Microsurg (2011) 0.76
Integrating B cell homeostasis and selection with BLyS. Arch Immunol Ther Exp (Warsz) (2003) 0.76
Beyond transitional selection: New roles for BLyS in peripheral tolerance. Drug Dev Res (2011) 0.76
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A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest (2017) 0.75
Strategies for B-lymphocyte repertoire remodeling in transplantation tolerance. Immunol Res (2011) 0.75
A systems approach to ethical problems. Ethics Behav (1991) 0.75
New wine in old bottles: expanding roles for B cells in transplantation tolerance. Semin Immunol (2012) 0.75
An increased frequency of autoantibody-inducing CD4+ T cells in pre-diseased lupus-prone mice. Int Immunol (2004) 0.75
What creates the dilemma in ethical dilemmas? Examples from psychological practice. Ethics Behav (1992) 0.75
Wave-number selection by target patterns and sidewalls in Rayleigh-Bénard convection. Phys Rev E Stat Nonlin Soft Matter Phys (2004) 0.75
Lateral canthopexy using the hollow needle technique. Plast Reconstr Surg (2006) 0.75