Published in Recent Pat CNS Drug Discov on May 01, 2011
Repetitive acute intermittent hypoxia increases expression of proteins associated with plasticity in the phrenic motor nucleus. Exp Neurol (2012) 1.01
Wnt activation of immortalized brain endothelial cells as a tool for generating a standardized model of the blood brain barrier in vitro. PLoS One (2013) 0.98
Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells. PLoS One (2012) 0.98
Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier. BMC Neurosci (2013) 0.94
A detailed method for preparation of a functional and flexible blood-brain barrier model using porcine brain endothelial cells. Brain Res (2013) 0.93
Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transport. J Vis Exp (2014) 0.85
Generation of an immortalized murine brain microvascular endothelial cell line as an in vitro blood brain barrier model. J Vis Exp (2012) 0.84
Optimization of endothelial cell growth in a murine in vitro blood-brain barrier model. Biotechnol J (2011) 0.81
A simple method for assessing free brain/free plasma ratios using an in vitro model of the blood brain barrier. PLoS One (2013) 0.80
Adapting coculture in vitro models of the blood-brain barrier for use in cancer research: maintaining an appropriate endothelial monolayer for the assessment of transendothelial migration. Lab Invest (2016) 0.80
In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells. Neural Regen Res (2015) 0.77
Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties. J Neurol Sci (2012) 0.77
Novel treatment strategies for brain tumors and metastases. Pharm Pat Anal (2014) 0.77
C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus. Immunology (2015) 0.76
Effects of Muscone on the Expression of P-gp, MMP-9 on Blood-Brain Barrier Model In Vitro. Cell Mol Neurobiol (2015) 0.75
Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters. Blood (2010) 3.15
Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology. Cell Mol Neurobiol (2005) 2.58
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes. Neurochem Int (2008) 2.06
Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production. Brain Res (2005) 1.76
Pericytes from brain microvessels strengthen the barrier integrity in primary cultures of rat brain endothelial cells. Cell Mol Neurobiol (2007) 1.68
A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor. J Immunol (2002) 1.59
HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells. J Neurosci Res (2003) 1.43
Signaling mechanisms of HIV-1 Tat-induced alterations of claudin-5 expression in brain endothelial cells. J Cereb Blood Flow Metab (2005) 1.33
14-3-3 protein, total tau and phosphorylated tau in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease and neurodegenerative disease in Japan. Cell Mol Neurobiol (2006) 1.23
Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice. Cell Mol Neurobiol (2008) 1.18
Schistosoma mansoni and alpha-galactosylceramide: prophylactic effect of Th1 Immune suppression in a mouse model of Graves' hyperthyroidism. J Immunol (2004) 1.11
The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells. J Cereb Blood Flow Metab (2007) 1.10
Effects of hypoxia on endothelial/pericytic co-culture model of the blood-brain barrier. Regul Pept (2004) 1.10
Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine. J Immunol (2003) 1.07
Pentosan polysulfate protects brain endothelial cells against bacterial lipopolysaccharide-induced damages. Neurochem Int (2006) 1.06
Endothelin-1 binding to endothelin receptors in the rat anterior pituitary gland: possible formation of an ETA-ETB receptor heterodimer. Cell Mol Neurobiol (2002) 1.01
Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine. Mol Pain (2010) 1.00
Intracellular transport of Toxoplasma gondii through the blood-brain barrier. J Neuroimmunol (2010) 0.98
Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells. PLoS One (2012) 0.98
Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models. Eur J Pharm Biopharm (2012) 0.95
Adrenomedullin improves the blood-brain barrier function through the expression of claudin-5. Cell Mol Neurobiol (2006) 0.93
A major role for non-major histocompatibility complex genes but not for microorganisms in a novel murine model of Graves' hyperthyroidism. Thyroid (2003) 0.93
Transient forebrain ischemia increases the blood-brain barrier permeability for albumin in stroke-prone spontaneously hypertensive rats. Cell Mol Neurobiol (2002) 0.92
Expression of MCP-1 in the hippocampus of SHRSP with ischemia-related delayed neuronal death. Cell Mol Neurobiol (2006) 0.92
DJ-1-binding compounds prevent oxidative stress-induced cell death and movement defect in Parkinson's disease model rats. J Neurochem (2008) 0.91
Uptake and efflux of quinacrine, a candidate for the treatment of prion diseases, at the blood-brain barrier. Cell Mol Neurobiol (2004) 0.91
Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier. Neurochem Int (2011) 0.90
A pitfall in diagnosis of human prion diseases using detection of protease-resistant prion protein in urine. Contamination with bacterial outer membrane proteins. J Biol Chem (2004) 0.89
Kinetic analysis of the toxicity of pharmaceutical excipients Cremophor EL and RH40 on endothelial and epithelial cells. J Pharm Sci (2013) 0.88
Applicability of sucrose laurate as surfactant in solid dispersions prepared by melt technology. Int J Pharm (2011) 0.87
Toxicity of quinacrine can be reduced by co-administration of P-glycoprotein inhibitor in sporadic Creutzfeldt-Jakob disease. Cell Mol Neurobiol (2004) 0.85
Neuroprotective effect of pentosan polysulphate on ischemia-related neuronal death of the hippocampus. Neurosci Lett (2006) 0.85
The effect of sucrose esters on a culture model of the nasal barrier. Toxicol In Vitro (2012) 0.84
Tissue plasminogen activator enhances the hypoxia/reoxygenation-induced impairment of the blood-brain barrier in a primary culture of rat brain endothelial cells. Cell Mol Neurobiol (2008) 0.84
Roles of tumor necrosis factor-related apoptosis-inducing ligand signaling pathway in granulosa cell apoptosis during atresia in pig ovaries. J Reprod Dev (2003) 0.83
Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity. J Alzheimers Dis (2010) 0.83
Effect of nicotine and polyaromtic hydrocarbons on cerebral endothelial cells. Cell Biol Int (2007) 0.83
Sodium hyaluronate as a mucoadhesive component in nasal formulation enhances delivery of molecules to brain tissue. Eur J Pharm Biopharm (2008) 0.83
Pentosan reduces osteonecrosis of femoral head in SHRSP. Clin Exp Hypertens (2010) 0.83
Persistent hypoglossal artery with hypoplasia of the vertebral and posterior communicating arteries. Anat Sci Int (2009) 0.83
Randomly methylated β-cyclodextrin derivatives enhance taxol permeability through human intestinal epithelial Caco-2 cell monolayer. J Pharm Sci (2011) 0.83
Docosahexaenoic acid reduces amyloid-β induced toxicity in cells of the neurovascular unit. J Alzheimers Dis (2013) 0.83
Adverse effect of cyclosporin A on barrier functions of cerebral microvascular endothelial cells after hypoxia-reoxygenation damage in vitro. Cell Mol Neurobiol (2007) 0.82
Inhibition of transforming growth factor-beta production in brain pericytes contributes to cyclosporin A-induced dysfunction of the blood-brain barrier. Cell Mol Neurobiol (2006) 0.82
Human immunodeficiency virus type 1 transport across the in vitro mouse brain endothelial cell monolayer. Exp Neurol (2005) 0.82
Activation of dorsolateral prefrontal cortex in a dual neuropsychological screening test: an fMRI approach. Behav Brain Funct (2012) 0.82
Adrenomedullin, an autocrine mediator of blood-brain barrier function. Hypertens Res (2003) 0.81
Effect of unpleasant loud noise on hippocampal activities during picture encoding: an fMRI study. Brain Cogn (2006) 0.81
Pitavastatin strengthens the barrier integrity in primary cultures of rat brain endothelial cells. Cell Mol Neurobiol (2010) 0.81
Initial contact of glioblastoma cells with existing normal brain endothelial cells strengthen the barrier function via fibroblast growth factor 2 secretion: a new in vitro blood-brain barrier model. Cell Mol Neurobiol (2013) 0.81
Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea. Anesth Analg (2004) 0.81
Human serum amyloid P component attenuates the bacterial lipopolysaccharide-induced increase in blood-brain barrier permeability in mice. Neurosci Lett (2003) 0.81
Osteonecrosis of femoral head in the stroke-prone spontaneously hypertensive rats, especially old rats. Clin Exp Hypertens (2008) 0.80
Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats. Acta Orthop (2012) 0.80
In vitro and in vivo characterization of meloxicam nanoparticles designed for nasal administration. Eur J Pharm Sci (2013) 0.79
Evaluation of cytotoxicity of surfactants used in self-micro emulsifying drug delivery systems and their effects on paracellular transport in Caco-2 cell monolayer. Eur J Pharm Sci (2012) 0.79
Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells. Brain Res (2006) 0.79
Cilostazol strengthens barrier integrity in brain endothelial cells. Cell Mol Neurobiol (2012) 0.79
Nitric oxide mediates cyclosporine-induced impairment of the blood-brain barrier in cocultures of mouse brain endothelial cells and rat astrocytes. Eur J Pharmacol (2004) 0.78
Sucrose esters increase drug penetration, but do not inhibit p-glycoprotein in caco-2 intestinal epithelial cells. J Pharm Sci (2014) 0.78
Possible protection of sinusoidal endothelial cells by endothelin B receptor during hepatic warm ischemia-reperfusion. Surg Today (2007) 0.77
Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats. Cell Mol Neurobiol (2010) 0.77
Retinoic acid and hydrocortisone strengthen the barrier function of human RPMI 2650 cells, a model for nasal epithelial permeability. Cytotechnology (2012) 0.77
Thyroid cancer immuno-therapy with retroviral and adenoviral vectors expressing granulocyte macrophage colony stimulating factor and interleukin-12 in a rat model. Clin Endocrinol (Oxf) (2003) 0.77
Intranasal delivery of human beta-amyloid peptide in rats: effective brain targeting. Cell Mol Neurobiol (2009) 0.77
Highly activated c-fos expression in specific brain regions (ependyma, circumventricular organs, choroid plexus) of histidine decarboxylase deficient mice in response to formalin-induced acute pain. Neuropharmacology (2007) 0.77
Preparation and investigation of mefenamic acid - polyethylene glycol - sucrose ester solid dispersions. Acta Pharm (2015) 0.76
Candesartan improves ischemia-induced impairment of the blood-brain barrier in vitro. Cell Mol Neurobiol (2014) 0.76
Efflux transport of serum amyloid P component at the blood-brain barrier. Eur J Microbiol Immunol (Bp) (2013) 0.76
Lercanidipine rescues hippocampus pyramidal neurons from mild ischemia-induced delayed neuronal death in SHRSP. Cell Mol Neurobiol (2011) 0.76