Published in J Neurochem on June 01, 2008
The role of cysteine oxidation in DJ-1 function and dysfunction. Antioxid Redox Signal (2011) 1.53
Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biol (2013) 1.24
Neuroprotective function of DJ-1 in Parkinson's disease. Oxid Med Cell Longev (2013) 1.12
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1. J Biol Chem (2009) 1.02
Protection of pancreatic beta-cells from various stress conditions is mediated by DJ-1. J Biol Chem (2010) 0.97
Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains. Mol Neurodegener (2009) 0.88
Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1. Mol Cell Proteomics (2011) 0.85
Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats. Mol Neurodegener (2011) 0.81
The role of DJ-1 in the oxidative stress cell death cascade after stroke. Neural Regen Res (2014) 0.79
Transcriptional activation of the cholecystokinin gene by DJ-1 through interaction of DJ-1 with RREB1 and the effect of DJ-1 on the cholecystokinin level in mice. PLoS One (2013) 0.78
Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection. Pharmacol Ther (2015) 0.78
Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. Int J Mol Sci (2009) 0.77
DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep (2004) 3.84
Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology. Cell Mol Neurobiol (2005) 2.58
Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem Biophys Res Commun (2004) 2.31
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes. Neurochem Int (2008) 2.06
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem Biophys Res Commun (2003) 1.96
The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J Biol Chem (2001) 1.86
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease. J Biol Chem (2003) 1.78
Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production. Brain Res (2005) 1.76
Pericytes from brain microvessels strengthen the barrier integrity in primary cultures of rat brain endothelial cells. Cell Mol Neurobiol (2007) 1.68
A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor. J Immunol (2002) 1.59
DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. Mol Cancer Res (2003) 1.53
Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients. Biochem Biophys Res Commun (2004) 1.53
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol Dis (2006) 1.47
Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. FASEB J (2002) 1.47
Proteasome inhibitors protect against degeneration of nigral dopaminergic neurons in hemiparkinsonian rats. J Pharmacol Sci (2005) 1.45
Photoinitiators enhanced 1,2-dichloropropane-induced cytotoxicity in human normal embryonic lung fibroblasts cells in vitro. Environ Sci Pollut Res Int (2014) 1.39
DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3. Int J Oncol (2005) 1.39
Trypsinogen hL expressed in the human lung is a new member of the trypsinogen family. Biol Pharm Bull (2003) 1.37
Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. J Neurochem (2007) 1.34
Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation. J Neurosci (2010) 1.33
The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytes. Mol Cell Biol (2003) 1.32
A role for the cleaved cytoplasmic domain of E-cadherin in the nucleus. J Biol Chem (2008) 1.32
Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radic Res (2005) 1.27
Efficient targeted mutagenesis in medaka using custom-designed transcription activator-like effector nucleases. Genetics (2013) 1.26
Disease model: Parkinson's disease. Trends Mol Med (2003) 1.24
14-3-3 protein, total tau and phosphorylated tau in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease and neurodegenerative disease in Japan. Cell Mol Neurobiol (2006) 1.23
Reconstruction of dopaminergic neural network and locomotion function in planarian regenerates. Dev Neurobiol (2007) 1.22
Detachment of brain pericytes from the basal lamina is involved in disruption of the blood-brain barrier caused by lipopolysaccharide-induced sepsis in mice. Cell Mol Neurobiol (2008) 1.18
Secretion of DJ-1 into the serum of patients with Parkinson's disease. Neurosci Lett (2007) 1.15
PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor. Exp Cell Res (2004) 1.15
Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats. J Pharmacol Sci (2007) 1.14
Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism. Brain Res (2007) 1.14
Synthesis and evaluation of 2-substituted 8-hydroxyadenines as potent interferon inducers with improved oral bioavailabilities. Bioorg Med Chem (2004) 1.13
Neuroprotective function of DJ-1 in Parkinson's disease. Oxid Med Cell Longev (2013) 1.12
Schistosoma mansoni and alpha-galactosylceramide: prophylactic effect of Th1 Immune suppression in a mouse model of Graves' hyperthyroidism. J Immunol (2004) 1.11
Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1. Biochem Biophys Res Commun (2005) 1.10
DJ-1 binds to mitochondrial complex I and maintains its activity. Biochem Biophys Res Commun (2009) 1.10
Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. Int J Oncol (2009) 1.10
Effects of hypoxia on endothelial/pericytic co-culture model of the blood-brain barrier. Regul Pept (2004) 1.10
Modulation of collagen fibrillogenesis by tenascin-X and type VI collagen. Exp Cell Res (2004) 1.09
Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine. J Immunol (2003) 1.07
Microglial transplantation increases amyloid-beta clearance in Alzheimer model rats. FEBS Lett (2007) 1.07
Pentosan polysulfate protects brain endothelial cells against bacterial lipopolysaccharide-induced damages. Neurochem Int (2006) 1.06
Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models. J Neurosci Res (2009) 1.05
Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1. Toxicol Sci (2005) 1.05
DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats. J Cereb Blood Flow Metab (2007) 1.05
CHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation. J Biol Chem (2012) 1.04
Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors. J Biol Chem (2010) 1.04
Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions. J Biol Chem (2003) 1.04
Negative regulation of the Wnt signal by MM-1 through inhibiting expression of the wnt4 gene. Exp Cell Res (2008) 1.04
Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. Biochem Biophys Res Commun (2002) 1.03
DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice. Biol Pharm Bull (2002) 1.02
Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism. Acta Crystallogr D Biol Crystallogr (2003) 1.02
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1. J Biol Chem (2009) 1.02
Endothelin-1 binding to endothelin receptors in the rat anterior pituitary gland: possible formation of an ETA-ETB receptor heterodimer. Cell Mol Neurobiol (2002) 1.01
EWS/ETS fusions activate telomerase in Ewing's tumors. Cancer Res (2003) 1.01
Serum tenascin-X strongly binds to vascular endothelial growth factor. Biol Pharm Bull (2009) 1.00