Published in Mol Cell Proteomics on May 23, 2011
Age-related changes in the plasticity and toughness of human cortical bone at multiple length scales. Proc Natl Acad Sci U S A (2011) 1.49
Effects of bone matrix proteins on fracture and fragility in osteoporosis. Curr Osteoporos Rep (2012) 1.08
Heterogeneous glycation of cancellous bone and its association with bone quality and fragility. PLoS One (2012) 1.01
Solid state NMR investigation of intact human bone quality: balancing issues and insight into the structure at the organic-mineral interface. J Phys Chem C Nanomater Interfaces (2012) 0.93
Bone microdamage, remodeling and bone fragility: how much damage is too much damage? Bonekey Rep (2015) 0.89
A therapeutic potential for marine skeletal proteins in bone regeneration. Mar Drugs (2013) 0.88
Bone composition: relationship to bone fragility and antiosteoporotic drug effects. Bonekey Rep (2013) 0.88
Biologically and diagenetically derived peptide modifications in moa collagens. Proc Biol Sci (2015) 0.86
Peptide sequences from the first Castoroides ohioensis skull and the utility of old museum collections for palaeoproteomics. Proc Biol Sci (2016) 0.81
Insulin-like growth factor 1, glycation and bone fragility: implications for fracture resistance of bone. PLoS One (2015) 0.80
Bone protein extraction without demineralization using principles from hydroxyapatite chromatography. Anal Biochem (2014) 0.80
Influence of carboxylation on osteocalcin detection by mass spectrometry. Rapid Commun Mass Spectrom (2016) 0.75
Glycation of human cortical and cancellous bone captures differences in the formation of Maillard reaction products between glucose and ribose. PLoS One (2015) 0.75
Laser capture microdissection. Science (1996) 12.21
Therapeutic approaches to bone diseases. Science (2000) 5.60
Increased bone formation in osteocalcin-deficient mice. Nature (1996) 4.91
Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone. Physiol Rev (1989) 3.87
Laser-capture microdissection. Nat Protoc (2006) 3.80
Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: a method for the removal of silver ions to enhance sensitivity. Electrophoresis (1999) 3.71
Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study. J Bone Miner Res (2007) 3.31
Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci U S A (1976) 3.15
Anabolism. Low mechanical signals strengthen long bones. Nature (2001) 2.79
Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus. Osteoporos Int (2010) 2.69
Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res (1998) 2.49
Influence of nonenzymatic glycation on biomechanical properties of cortical bone. Bone (2001) 2.40
Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone. J Biol Chem (1987) 2.40
Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone. Calcif Tissue Int (2002) 1.91
Control of osteopontin signaling and function by post-translational phosphorylation and protein folding. J Cell Biochem (2007) 1.90
Effects of non-enzymatic glycation on cancellous bone fragility. Bone (2006) 1.87
TGF-beta regulates the mechanical properties and composition of bone matrix. Proc Natl Acad Sci U S A (2005) 1.83
Normal and pathological remodeling of human trabecular bone: three dimensional reconstruction of the remodeling sequence in normals and in metabolic bone disease. Endocr Rev (1986) 1.78
Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin. Bone (1998) 1.76
Rising crack-growth-resistance behavior in cortical bone: implications for toughness measurements. J Biomech (2004) 1.62
Tissue engineering of complex tooth structures on biodegradable polymer scaffolds. J Dent Res (2002) 1.61
Age-related change in the damage morphology of human cortical bone and its role in bone fragility. Bone (2005) 1.55
Trabecular microfracture and the influence of pyridinium and non-enzymatic glycation-mediated collagen cross-links. Bone (2005) 1.53
Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra. Osteoporos Int (2007) 1.47
Advanced glycation end products and bone loss during aging. Ann N Y Acad Sci (2005) 1.45
Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation. J Biol Chem (2006) 1.36
Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen. Anal Biochem (1997) 1.36
The role of the collagen matrix in skeletal fragility. Curr Osteoporos Rep (2007) 1.32
Bone matrix proteins: their function, regulation, and relationship to osteoporosis. Osteoporos Int (2003) 1.23
Reductions in degree of mineralization and enzymatic collagen cross-links and increases in glycation-induced pentosidine in the femoral neck cortex in cases of femoral neck fracture. Osteoporos Int (2006) 1.23
Osteopontin posttranslational modifications, possibly phosphorylation, are required for in vitro bone resorption but not osteoclast adhesion. Bone (2002) 1.21
Nanoscale ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy. Nano Lett (2007) 1.18
Reconstruction of the formative site in iliac trabecular bone in 20 normal individuals employing a kinetic model for matrix and mineral apposition. Metab Bone Dis Relat Res (1984) 1.14
Morphology, localization and accumulation of in vivo microdamage in human cortical bone. Bone (2006) 1.11
Osteocalcin protein sequences of Neanderthals and modern primates. Proc Natl Acad Sci U S A (2005) 1.07
Osteopontin: an interfacial extracellular matrix protein in mineralized tissues. Connect Tissue Res (1996) 1.07
Bone protects proteins over thousands of years: extraction, analysis, and interpretation of extracellular matrix proteins in archeological skeletal remains. Am J Phys Anthropol (2004) 1.05
The chemistry of the collagen cross-links. The absence of reduction of dehydrolysinonorleucine and dehydrohydroxylysinonorleucine in vivo. Biochem J (1971) 1.03
Postnatal growth, differentiation, and aging of the mouse intervertebral disc. Spine (Phila Pa 1976) (2009) 1.03
UPLC methodology for identification and quantitation of naturally fluorescent crosslinks in proteins: a study of bone collagen. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.99
Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue. Bone (2006) 0.98
Molecular and cellular characterization of SEL-OB/SVEP1 in osteogenic cells in vivo and in vitro. J Cell Physiol (2006) 0.95
Kinetics of osteoclasts and their nuclei in evolving secondary Haversian systems. J Anat (1981) 0.93
Concentration of insulin-like growth factor (IGF)-I and -II in iliac crest bone matrix from pre- and postmenopausal women: relationship to age, menopause, bone turnover, bone volume, and circulating IGFs. J Clin Endocrinol Metab (1998) 0.92
In vivo expression of RANKL in the rat dental follicle as determined by laser capture microdissection. Arch Oral Biol (2004) 0.92
Age- and gender-related changes in the distribution of osteocalcin in the extracellular matrix of normal male and female bone. Possible involvement of osteocalcin in bone remodeling. J Clin Invest (1994) 0.91
Association of specific proteolytic processing of bone sialoprotein and bone acidic glycoprotein-75 with mineralization within biomineralization foci. J Biol Chem (2007) 0.91
"Glycated" osteocalcin in human and bovine bone. The effect of age. J Biol Chem (1986) 0.89
Collagen glycation and its role in fracture properties of bone. J Musculoskelet Neuronal Interact (2005) 0.88
Variations in extractable collagen of bone and skin with age and growth. J Gerontol (1966) 0.87
Matrix concentration of insulin-like growth factor I (IGF-I) is negatively associated with biomechanical properties of human tibial cancellous bone within individual subjects. Calcif Tissue Int (2005) 0.86
Affected skeletal growth but normal bone mineralization in rat offspring after prenatal dexamethasone exposure. J Endocrinol (2002) 0.81
Gene expression in a pure population of odontoblasts isolated by laser-capture microdissection. J Dent Res (2001) 0.81
Soluble collagen in bone. Nature (1961) 0.81
Normal mineralization and nanostructure of sclerotic bone in mice overexpressing Fra-1. Bone (2004) 0.81
A SYNCHRONOUS GROUP OF MAMMALLIAN CELLS WHOSE IN VIVO BEHAVIOR CAN BE STUDIED. Henry Ford Hosp Med Bull (1965) 0.76
Structural basis of protein kinetic stability: resistance to sodium dodecyl sulfate suggests a central role for rigidity and a bias toward beta-sheet structure. Biochemistry (2004) 1.73
Age-related change in the damage morphology of human cortical bone and its role in bone fragility. Bone (2005) 1.55
Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity. Bone (2009) 1.47
Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE. Proc Natl Acad Sci U S A (2007) 1.47
Dilatational band formation in bone. Proc Natl Acad Sci U S A (2012) 1.32
Morphology, localization and accumulation of in vivo microdamage in human cortical bone. Bone (2006) 1.11
Effects of bone matrix proteins on fracture and fragility in osteoporosis. Curr Osteoporos Rep (2012) 1.08
Microarchitecture influences microdamage accumulation in human vertebral trabecular bone. J Bone Miner Res (2008) 1.06
Decreased stability and increased formation of soluble aggregates by immature superoxide dismutase do not account for disease severity in ALS. Proc Natl Acad Sci U S A (2011) 1.06
Trabecular shear stresses predict in vivo linear microcrack density but not diffuse damage in human vertebral cancellous bone. Ann Biomed Eng (2003) 1.05
Kinetic stability of Cu/Zn superoxide dismutase is dependent on its metal ligands: implications for ALS. Biochemistry (2004) 1.04
Heterogeneous glycation of cancellous bone and its association with bone quality and fragility. PLoS One (2012) 1.01
Interactions between microstructural and geometrical adaptation in human cortical bone. J Orthop Res (2006) 1.01
Cohesive finite element modeling of age-related toughness loss in human cortical bone. J Biomech (2005) 0.99
UPLC methodology for identification and quantitation of naturally fluorescent crosslinks in proteins: a study of bone collagen. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.99
Modification of cysteine 111 in Cu/Zn superoxide dismutase results in altered spectroscopic and biophysical properties. Protein Sci (2004) 0.95
Role of trabecular microarchitecture in the formation, accumulation, and morphology of microdamage in human cancellous bone. J Orthop Res (2011) 0.94
NMR investigation of the role of osteocalcin and osteopontin at the organic-inorganic interface in bone. Langmuir (2013) 0.93
Solid state NMR investigation of intact human bone quality: balancing issues and insight into the structure at the organic-mineral interface. J Phys Chem C Nanomater Interfaces (2012) 0.93
Equilibrium denaturation studies of the Escherichia coli factor for inversion stimulation: implications for in vivo function. Protein Sci (2002) 0.93
Cu/Zn superoxide dismutase can form pore-like structures. Biochem Biophys Res Commun (2003) 0.93
Cytochrome C on silica nanoparticles: influence of nanoparticle size on protein structure, stability, and activity. Small (2009) 0.93
Adolescent girls with anorexia nervosa have impaired cortical and trabecular microarchitecture and lower estimated bone strength at the distal radius. J Clin Endocrinol Metab (2013) 0.93
Characterization of interactions between heparin/glycosaminoglycan and adeno-associated virus. Biochemistry (2013) 0.93
Effects of intracortical porosity on fracture toughness in aging human bone: a microCT-based cohesive finite element study. J Biomech Eng (2007) 0.93
A review of rodent models of type 2 diabetic skeletal fragility. J Bone Miner Res (2014) 0.92
From hexamer to amyloid: marginal stability of apolipoprotein SAA2.2 leads to in vitro fibril formation at physiological temperature. Amyloid (2005) 0.90
Common and variable contributions of Fis residues to high-affinity binding at different DNA sequences. J Bacteriol (2006) 0.90
Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2. J Biol Chem (2012) 0.89
From two-state to three-state: the effect of the P61A mutation on the dynamics and stability of the factor for inversion stimulation results in an altered equilibrium denaturation mechanism. Biochemistry (2002) 0.87
Effect of zinc, copper, and calcium on the structure and stability of serum amyloid A. Biochemistry (2007) 0.85
The interaction between apolipoprotein serum amyloid A and high-density lipoprotein. Biochem Biophys Res Commun (2004) 0.84
Serum amyloid A 2.2 refolds into a octameric oligomer that slowly converts to a more stable hexamer. Biochem Biophys Res Commun (2011) 0.84
Characterization of the oligomerization and aggregation of human Serum Amyloid A. PLoS One (2013) 0.84
Anisotropy of age-related toughness loss in human cortical bone: a finite element study. J Biomech (2006) 0.84
Quantifying the kinetic stability of hyperstable proteins via time-dependent SDS trapping. Biochemistry (2011) 0.83
Urea-induced denaturation of apolipoprotein serum amyloid A reveals marginal stability of hexamer. Protein Sci (2005) 0.83
Effects of collagen crosslinking on tissue fragility. Clin Biomech (Bristol, Avon) (2007) 0.82
The location of an engineered inter-subunit disulfide bond in factor for inversion stimulation (FIS) affects the denaturation pathway and cooperativity. Biochemistry (2006) 0.81
Small animal bone biomechanics. Bone (2008) 0.81
Geofold: topology-based protein unfolding pathways capture the effects of engineered disulfides on kinetic stability. Proteins (2011) 0.80
Dominant role of copper in the kinetic stability of Cu/Zn superoxide dismutase. Biochem Biophys Res Commun (2005) 0.80
Do prokaryotes have more kinetically stable proteins than eukaryotic organisms? Biochemistry (2010) 0.79
Variable contributions of tyrosine residues to the structural and spectroscopic properties of the factor for inversion stimulation. Biochemistry (2004) 0.79
The effect of strain rate on fracture toughness of human cortical bone: a finite element study. J Mech Behav Biomed Mater (2011) 0.79
Inflammation protein SAA2.2 spontaneously forms marginally stable amyloid fibrils at physiological temperature. Biochemistry (2011) 0.78
Green-lighting green fluorescent protein: faster and more efficient folding by eliminating a cis-trans peptide isomerization event. Protein Sci (2014) 0.78
Multiscale imaging of bone microdamage. Connect Tissue Res (2015) 0.77
Distinctive interactions in the holoenzyme formation for two isoforms of glutamate decarboxylase. Biochim Biophys Acta (2003) 0.77
P61A mutation in the factor for inversion stimulation results in a thermostable dimeric intermediate. Biochemistry (2005) 0.77
Identifying kinetically stable proteins with capillary electrophoresis. Protein Sci (2010) 0.76
Influence of the carboxy terminus of serum amyloid A on protein oligomerization, misfolding, and fibril formation. Biochemistry (2012) 0.76
The role of the local environment of engineered Tyr to Trp substitutions for probing the denaturation mechanism of FIS. Protein Sci (2011) 0.75
Correction: Advanced Glycation Endproducts and Bone Material Properties in Type 1 Diabetic Mice. PLoS One (2016) 0.75
Evaluation of the influence of strain rate on Colles' fracture load. J Biomech (2012) 0.75
Do Non-collagenous Proteins Affect Skeletal Mechanical Properties? Calcif Tissue Int (2015) 0.75
A truncated peptide model of the mutant P61A FIS forms a stable dimer. Biochim Biophys Acta (2006) 0.75
A tribute to Robert L. Spilker. Biomech Model Mechanobiol (2013) 0.75