Published in Nat Prod Commun on May 01, 2011
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Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet (2003) 8.30
Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study. Lancet (2005) 4.82
Regulatory T cells are expanded in blood and disease sites in patients with tuberculosis. Am J Respir Crit Care Med (2005) 4.72
Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis. Lancet Infect Dis (2011) 4.00
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Cellular immune correlates of protection against symptomatic pandemic influenza. Nat Med (2013) 3.03
Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food Chem Toxicol (2007) 2.99
Improved diagnostic evaluation of suspected tuberculosis. Ann Intern Med (2008) 2.85
Pharmacological and toxicological properties of Nigella sativa. Phytother Res (2003) 2.78
Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study. Thorax (2011) 2.60
Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load. J Immunol (2007) 2.40
Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count. AIDS (2005) 2.38
Incidence of multidrug-resistant tuberculosis in urban and rural India and implications for prevention. Clin Infect Dis (2003) 2.38
Prognostic value of a T-cell-based, interferon-gamma biomarker in children with tuberculosis contact. Ann Intern Med (2008) 2.36
A comparison between two strategies for monitoring hepatic function during antituberculous therapy. Am J Respir Crit Care Med (2011) 2.22
Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. PLoS Negl Trop Dis (2010) 2.08
Characterization of the CD4+ T cell response to Epstein-Barr virus during primary and persistent infection. J Exp Med (2003) 2.01
Increased risk of Mycobacterium tuberculosis infection in household child contacts exposed to passive tobacco smoke. Pediatr Infect Dis J (2014) 1.97
Ex vivo characterization of early secretory antigenic target 6-specific T cells at sites of active disease in pleural tuberculosis. Clin Infect Dis (2004) 1.88
Evaluation of immigrant tuberculosis screening in industrialized countries. Emerg Infect Dis (2012) 1.81
T cell-based tracking of multidrug resistant tuberculosis infection after brief exposure. Am J Respir Crit Care Med (2004) 1.70
Counting antigen-specific T cells: a new approach for monitoring response to tuberculosis treatment? Clin Infect Dis (2004) 1.68
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS Negl Trop Dis (2011) 1.66
Enzyme-linked immunospot and tuberculin skin testing to detect latent tuberculosis infection. Am J Respir Crit Care Med (2005) 1.58
Inhibitory activity of marine sponge-derived natural products against parasitic protozoa. Mar Drugs (2010) 1.52
Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: in vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. Antimicrob Agents Chemother (2006) 1.48
High incidence of the Beijing genotype among multidrug-resistant isolates of Mycobacterium tuberculosis in a tertiary care center in Mumbai, India. Clin Infect Dis (2005) 1.47
Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza. Planta Med (2011) 1.46
Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis. PLoS One (2010) 1.45
Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A (2011) 1.35
Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles. J Immunol (2004) 1.34
Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection. Infect Immun (2004) 1.30
The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine. Biochem Pharmacol (2003) 1.28
Phytochemical, pharmacological and toxicological aspects of Hibiscus sabdariffa L.: a review. Phytother Res (2005) 1.26
Antiparasitic agents: new drugs on the horizon. Curr Opin Pharmacol (2012) 1.25
Whole-blood flow-cytometric analysis of antigen-specific CD4 T-cell cytokine profiles distinguishes active tuberculosis from non-active states. PLoS One (2011) 1.24
Community-based evaluation of immigrant tuberculosis screening using interferon γ release assays and tuberculin skin testing: observational study and economic analysis. Thorax (2012) 1.21
Undetected multidrug-resistant tuberculosis amplified by first-line therapy in mixed infection. Emerg Infect Dis (2013) 1.20
T-cell immunophenotyping distinguishes active from latent tuberculosis. J Infect Dis (2013) 1.18
Ethnicity and mycobacterial lineage as determinants of tuberculosis disease phenotype. Thorax (2012) 1.14
Experimental gentamicin nephrotoxicity and agents that modify it: a mini-review of recent research. Basic Clin Pharmacol Toxicol (2011) 1.12
Tuberculin skin testing underestimates a high prevalence of latent tuberculosis infection in hemodialysis patients. Kidney Int (2004) 1.11
Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters. Phytother Res (2010) 1.08
Interferon gamma assays for tuberculosis. Lancet Infect Dis (2005) 1.08
DNA binding affinity of bisguanidine and bis(2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity. J Med Chem (2006) 1.08
Insulin use in elderly adults: risk of hypoglycemia and strategies for care. J Am Geriatr Soc (2012) 1.07
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis. Eur J Med Chem (2011) 1.07
A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection. J Clin Invest (2011) 1.07
Biological effects of gum arabic: a review of some recent research. Food Chem Toxicol (2008) 1.06
New bis(2-aminoimidazoline) and bisguanidine DNA minor groove binders with potent in vivo antitrypanosomal and antiplasmodial activity. J Med Chem (2008) 1.06
Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives. J Med Chem (2007) 1.05
Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis. Antimicrob Agents Chemother (2010) 1.04
Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol. PLoS Negl Trop Dis (2013) 1.04
The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. J Ethnopharmacol (2010) 1.04
Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis. Antimicrob Agents Chemother (2009) 1.03
Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice. PLoS Negl Trop Dis (2011) 1.03
Bromopyrrole alkaloids as lead compounds against protozoan parasites. Mar Drugs (2010) 1.03
Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from Microcystis aeruginosa PCC 7806 and their antiparasite evaluation. J Nat Prod (2008) 1.03
Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum. J Org Chem (2011) 1.03
Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign. PLoS Negl Trop Dis (2012) 1.02
IGRAs--the gateway to T cell based TB diagnosis. Methods (2013) 1.02
Impact of weight gain on outcomes in type 2 diabetes. Curr Med Res Opin (2011) 1.02
T-cell-based diagnosis of neonatal multidrug-resistant latent tuberculosis infection. Pediatrics (2007) 1.01
Dietary chalcones with chemopreventive and chemotherapeutic potential. Genes Nutr (2011) 1.00
BCG vaccination: 90 years on and still so much to learn ... Thorax (2010) 1.00
β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. Bioorg Med Chem (2011) 0.99
Quinuclidine derivatives as potential antiparasitics. Antimicrob Agents Chemother (2007) 0.99
Early diagnosis of subclinical multidrug-resistant tuberculosis. Ann Intern Med (2004) 0.99
Identifying recent Mycobacterium tuberculosis transmission in the setting of high HIV and TB burden. Thorax (2010) 0.98
Quantitative structure--antiprotozoal activity relationships of sesquiterpene lactones. Molecules (2009) 0.98
Microcionamides A and B, bioactive peptides from the philippine sponge Clathria (Thalysias) abietina. J Org Chem (2004) 0.98
Mycobacterium tuberculosis-specific cellular immune profiles suggest bacillary persistence decades after spontaneous cure in untreated tuberculosis. J Infect Dis (2010) 0.98
Analogues of thiolactomycin as potential antimalarial agents. J Med Chem (2005) 0.97
Antitrypanosomal sesquiterpene lactones from Saussurea costus. Fitoterapia (2011) 0.96
Novel M tuberculosis antigen-specific T-cells are early markers of infection and disease progression. PLoS One (2011) 0.96
Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives. J Med Chem (2010) 0.96
Cynaropicrin: the first plant natural product with in vivo activity against Trypanosoma brucei. Planta Med (2012) 0.95
Antiplasmodial and antitrypanosomal activity of new esters and ethers of 4-dialkylaminobicyclo[2.2.2]octan-2-ols. Eur J Pharm Sci (2006) 0.95
Discovery and structure-activity relationships of pyrrolone antimalarials. J Med Chem (2013) 0.95
Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. J Nat Prod (2011) 0.95
Use of T cell-based diagnosis of tuberculosis infection to optimize interpretation of tuberculin skin testing for child tuberculosis contacts. Clin Infect Dis (2009) 0.94
Predominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults. Eur J Immunol (2012) 0.94
Pentafluorosulfanyl as a novel building block for enzyme inhibitors: trypanothione reductase inhibition and antiprotozoal activities of diarylamines. Chembiochem (2009) 0.94
Manadoperoxides, a new class of potent antitrypanosomal agents of marine origin. Org Biomol Chem (2012) 0.94