Published in Alcohol Clin Exp Res on October 01, 1978
Involvement of a single thiol group in the conversion of the NAD+-dependent activity of rat liver xanthine oxidoreductase to the O2-dependent activity. Biochem J (1982) 0.78
Disulfiram metabolite S-methyl-N,N-diethylthiocarbamate quantitation in human plasma with reverse phase ultra performance liquid chromatography and mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.77
Biological effects of short-term, high-concentration exposure to methyl isocyanate. I. Study objectives and inhalation exposure design. Environ Health Perspect (1987) 1.16
Acute inhalation studies with methyl isocyanate vapor. II. Respiratory tract changes in guinea pigs, rats, and mice. Fundam Appl Toxicol (1986) 1.13
Biological effects of short-term, high-concentration exposure to methyl isocyanate. II. Blood chemistry and hematologic evaluations. Environ Health Perspect (1987) 1.11
Elimination kinetics of disulfiram in alcoholics after single and repeated doses. Clin Pharmacol Ther (1984) 1.11
Biological effects of short-term, high-concentration exposure to methyl isocyanate. III. Influence on gas exchange in the guinea pig lung. Environ Health Perspect (1987) 1.09
Biological effects of short-term, high-concentration exposure to methyl isocyanate. V. Morphologic evaluation of rat and guinea pig lungs. Environ Health Perspect (1987) 1.08
Ethylene glycol monobutyl ether: acute, 9-day, and 90-day vapor inhalation studies in Fischer 344 rats. Toxicol Appl Pharmacol (1983) 1.06
Respiratory tract changes in guinea pigs, rats, and mice following a single six-hour exposure to methyl isocyanate vapor. Environ Health Perspect (1987) 1.06
Acute inhalation studies with methyl isocyanate vapor. I. Methodology and LC50 determinations in guinea pigs, rats, and mice. Fundam Appl Toxicol (1986) 1.03
Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram. Drug Metab Dispos (1995) 1.03
Methyl isocyanate subchronic vapor inhalation studies with Fischer 344 rats. Fundam Appl Toxicol (1986) 1.02
Carbamoylation of brain glutamate receptors by a disulfiram metabolite. J Biol Chem (1997) 0.99
In vitro and in vivo inhibition of rat liver aldehyde dehydrogenase by S-methyl N,N-diethylthiolcarbamate sulfoxide, a new metabolite of disulfiram. Biochem Pharmacol (1992) 0.98
Role of taurine in regulation of intracellular calcium level and neuroprotective function in cultured neurons. J Neurosci Res (2001) 0.97
Methyl isocyanate eight-day vapor inhalation study with Fischer 344 rats. Environ Health Perspect (1987) 0.95
Biological effects of short-term, high-concentration exposure to methyl isocyanate. VI. In vitro and in vivo complement activation studies. Environ Health Perspect (1987) 0.95
Eighty-five day postexposure follow-up study in Fischer 344 rats after repeated exposures to methyl isocyanate vapor. Environ Health Perspect (1987) 0.91
The acute toxicity and primary irritancy of N-benzyl-N,N-dimethylamine. Drug Chem Toxicol (1985) 0.91
Comparative aspects of disulfiram and its metabolites in the disulfiram-ethanol reaction in the rat. Biochem Pharmacol (1989) 0.90
Distribution of S35 disulfiram and metabolites in mice, and metabolism of S35 disulfiram in the dog. Res Commun Chem Pathol Pharmacol (1978) 0.89
Developmental stages of the bob-white quail embryo (Colinus virginianus). Biol Bull (1965) 0.88
Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate. Biochem Pharmacol (1993) 0.87
Disulfiram metabolism as a requirement for the inhibition of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol (1991) 0.87
A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate. Toxicol Sci (2000) 0.86
In vivo pharmacodynamic studies of the disulfiram metabolite S-methyl N,N-diethylthiolcarbamate sulfoxide: inhibition of liver aldehyde dehydrogenase. Alcohol Clin Exp Res (1994) 0.85
Disulfiram distribution and elimination in the rat after oral and intraperitoneal administration. Alcohol Clin Exp Res (1980) 0.84
S-methyl-N,N-diethylthiolcarbamate: a disulfiram metabolite and potent rat liver mitochondrial low Km aldehyde dehydrogenase inhibitor. Alcohol (1990) 0.83
Dimethylethanolamine: acute, 2-week, and 13-week inhalation toxicity studies in rats. Fundam Appl Toxicol (1987) 0.83
Bioactivation of S-methyl N,N-diethylthiolcarbamate to S-methyl N,N-diethylthiolcarbamate sulfoxide. Implications for the role of cytochrome P450. Biochem Pharmacol (1993) 0.83
A rapid and simple radioactive method for the determination of disulfiram and its metabolites from a single sample of biological fluid or tissue. Res Commun Chem Pathol Pharmacol (1977) 0.82
Characterization of diethyldithiocarbamate methyl ester sulfine as an intermediate in the bioactivation of disulfiram. J Pharmacol Exp Ther (1995) 0.81
Evaluation of exposure to water aerosol or air by nose-only or whole-body inhalation procedures for CD-1 mice in developmental toxicity studies. Fundam Appl Toxicol (1994) 0.81
Diethyldithiocarbamic acid-methyl ester: a metabolite of disulfiram and its alcohol sensitizing properties in the disulfiram-ethanol reaction. Alcohol (1988) 0.81
Pulmonary fibrosis produced in F-344 rats by subchronic inhalation of aerosols of a 4000 molecular weight ethylene oxide/propylene oxide polymer. Fundam Appl Toxicol (1988) 0.81
S-methyl N,N-diethylthiolcarbamate sulfone, an in vitro and in vivo inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase. Biochem Pharmacol (1994) 0.81
Protein phosphorylation and taurine biosynthesis in vivo and in vitro. J Neurosci (1997) 0.81
S-methyl-N,N-diethylthiocarbamate sulfoxide elicits neuroprotective effect against N-methyl-D-aspartate receptor-mediated neurotoxicity. J Biomed Sci (2001) 0.80
Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation. Alcohol Clin Exp Res (1998) 0.80
Protection with disulfiram from central and pulmonary oxygen toxicity. Biochem Pharmacol (1971) 0.80
Subchronic toxicity study of dicyclopentadiene vapor in rats. Toxicol Ind Health (1995) 0.80
Acute and 2-week inhalation toxicity studies on aerosols of selected ethylene oxide/propylene oxide polymers in rats. Fundam Appl Toxicol (1987) 0.80
Enzymic cyclization of trans,trans,trans-18,19-dihydrosqualene 2,3-oxide. J Am Chem Soc (1967) 0.80
Evaluation of 13-week inhalation toxicity study on methyl t-butyl ether (MTBE) in Fischer 344 rats. J Appl Toxicol (1997) 0.80
Inhibition of rat liver low Km aldehyde dehydrogenase by thiocarbamate herbicides. Occupational implications. Biochem Pharmacol (1995) 0.80
Effect of disulfiram on oxygen toxicity in beagle dogs. Aerosp Med (1974) 0.79
Free radical formation and lipid peroxidation in rat and mouse cerebral cortex slices exposed to high oxygen pressure. Brain Res (1982) 0.79
Isolated perfused lung histamine release, lipid peroxidation, and tissue superoxide dismutase from rats exposed to normobaric hyperoxia. Toxicology (1986) 0.79
Determination of disulfiram and metabolites from biological fluids by high-performance liquid chromatography. J Chromatogr (1980) 0.79
Regulation of taurine biosynthesis and its physiological significance in the brain. Adv Exp Med Biol (1998) 0.79
Mode of action of taurine and regulation dynamics of its synthesis in the CNS. Adv Exp Med Biol (2000) 0.78
A 14-week vapor inhalation toxicity study of methyl isobutyl ketone. Fundam Appl Toxicol (1987) 0.78
Brain energetics in oxygen-induced convulsions. J Neurochem (1974) 0.77
Diethyldithiocarbamic acid-methyl ester distribution, elimination, and LD50 in the rat after intraperitoneal administration. Alcohol Clin Exp Res (1983) 0.77
Two-generation reproductive toxicity study of inhaled toluene diisocyanate vapor in CD rats. Toxicol Sci (1999) 0.77
Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. Drug Chem Toxicol (1989) 0.77
Diethyldithiocarbamate methyl ester sulfoxide, an inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase and putative metabolite of disulfiram. Alcohol Clin Exp Res (1994) 0.77
Ammonia production in inhalation chambers and its relevance to chlorine inhalation studies. Toxicol Appl Pharmacol (1979) 0.77
NADPH-dependent, regioselective S-oxidation of a thionosulfur- and thioether-containing xenobiotic, diethyldithiocarbamate methyl ester by rat liver microsomes. Drug Metab Dispos (1994) 0.76
Developmental toxicity evaluation of inhaled toluene diisocyanate vapor in CD rats. Toxicol Sci (1999) 0.76
Brain gamma-aminobutyric acid, glutamic acid decarboxylase, glutamate, and ammonia in mice during hyperbaric oxygenation. J Neurochem (1977) 0.76
Glutathione- and glutathione-S-transferase-dependent oxidative desulfuration of the thione xenobiotic diethyldithiocarbamate methyl ester. Mol Pharmacol (1994) 0.76
Cerebral oxidized and reduced nicotinamide-adenine dinucleotide phosphate and glucose 6-phosphate dehydrogenase in mice during exposure to high oxygen pressure. Biochem J (1978) 0.76
Neurotoxic effect of acamprosate, n-acetyl-homotaurine, in cultured neurons. J Biomed Sci (2001) 0.75
Teratologic evaluation of ethylene glycol monobutyl ether in Fischer 344 rats and New Zealand white rabbits following inhalation exposure. Environ Health Perspect (1984) 0.75
Segregation kinetics of particulate solids systems. IV. Effect of particle shape on energy requirements. J Pharm Sci (1967) 0.75
Elimination characteristics of disulfiram over time in five alcoholic volunteers: a preliminary study. Am J Psychiatry (1982) 0.75
Acute, 9-day, and 13-week vapor inhalation studies on ethylene glycol monohexyl ether. Fundam Appl Toxicol (1987) 0.75
Evaluation of the developmental toxicity of ethylene glycol aerosol in CD-1 mice by nose-only exposure. Fundam Appl Toxicol (1995) 0.75
Hyperbaric oxygenation and brain norepinephrine and 5-hydroxytryptamine: oxygen-pressure interactions. Life Sci (1969) 0.75
Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation. Fundam Appl Toxicol (1987) 0.75
The role of lipid, free radical initiator, and oxygen on the kinetics of lipid peroxidation. Toxicol Appl Pharmacol (1982) 0.75
Segregation kinetics of particulate solids systems. 3. Dependence on agitation intensity. J Pharm Sci (1965) 0.75
The effect of in vivo hyperoxic exposure on the release of endogenous histamine from the rat isolated perfused lung. Toxicol Appl Pharmacol (1984) 0.75
Glutathione carbamoylation with S-methyl N,N-diethylthiolcarbamate sulfoxide and sulfone. Mitochondrial low Km aldehyde dehydrogenase inhibition and implications for its alcohol-deterrent action. Biochem Pharmacol (1998) 0.75
2,4-Pentanedione: 9-day and 14-week vapor inhalation studies in Fischer-344 rats. Fundam Appl Toxicol (1986) 0.75
Short-term and subchronic repeated exposure studies with 5-ethylidene-2-norbornene vapor in the rat. J Appl Toxicol (1997) 0.75
Toxicology of methyl isocyanate. Rev Environ Contam Toxicol (1988) 0.75
Cerebral and blood glucose in central oxygen poisoning. Undersea Biomed Res (1978) 0.75
The acute toxicity of tris(dimethylamino)silane. Toxicol Ind Health (1989) 0.75
Plasma measurements of disulfiram and its metabolites in a case of severe disulfiram-ethanol reaction. Psychiatr J Univ Ott (1986) 0.75
Pulmonary oxygen toxicity in the rat and the role of histamine. Biochem Pharmacol (1986) 0.75
Evaluation of the developmental toxicity of ethylene glycol aerosol in the CD rat and CD-1 mouse by whole-body exposure. Fundam Appl Toxicol (1995) 0.75
Case report of acute disulfiram overdose. Am J Psychiatry (1983) 0.75
Development toxicity evaluation of inhaled nitrobenzene in CD rats. Fundam Appl Toxicol (1987) 0.75
Hepatotoxicity in guinea pigs following acute inhalation exposure to 1,1-dichloro-2,2,2-trifluoroethane. Toxicol Pathol (1995) 0.75
Air Force approach to risk assessment for halon replacements. Toxicol Lett (1993) 0.75
The acute toxicity and primary irritancy of 2,4-pentanedione. Drug Chem Toxicol (1986) 0.75
Central neurotoxicity induced by subchronic exposure to 2,4-pentanedione vapour. Hum Exp Toxicol (1995) 0.75
Brain norepinephrine and serotonin in central oxygen toxicity. Life Sci I (1971) 0.75
Dominant lethal assay of 2,4-pentanedione vapor in Fischer 344 rats. Toxicol Ind Health (1989) 0.75
Post-mortem degradation kinetics of brain norepinephrine. Biochem Pharmacol (1973) 0.75
Glutathione and non-protein sulfhydryl in cerebral cortex and lung in mice exposed to high oxygen pressure. Toxicology (1982) 0.75
NAD+ and NADH in brain cortex from mice exposed to high oxygen pressure. Toxicology (1982) 0.75
Acute vapour inhalation toxicity of acrolein and its influence as a trace contaminant in 2-methoxy-3,4-dihydro-2H-pyran. Hum Toxicol (1989) 0.75
Effect of high oxygen pressure on brain norepinephrine and serotonin turnover. Eur J Pharmacol (1973) 0.75