Published in Bioorg Med Chem Lett on May 06, 2011
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Happy birthday cell penetrating peptides: already 20 years. Biochim Biophys Acta (2010) 0.95
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Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach. Proc Natl Acad Sci U S A (2009) 1.79
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Mitogen-activated protein kinase phosphatase-3 is a tumor promoter target in initiated cells that express oncogenic Ras. J Biol Chem (2004) 1.10
Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP). Biochemistry (2003) 1.09
Allosteric regulation of SERCA by phosphorylation-mediated conformational shift of phospholamban. Proc Natl Acad Sci U S A (2013) 1.08
A highly efficient catalyst for oxime ligation and hydrazone-oxime exchange suitable for bioconjugation. Bioconjug Chem (2013) 1.06
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Biochemical and structural studies with prenyl diphosphate analogues provide insights into isoprenoid recognition by protein farnesyl transferase. Biochemistry (2003) 1.03
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Use of synthetic isoprenoid analogues for understanding protein prenyltransferase mechanism and structure. Curr Top Med Chem (2003) 0.98
T3 increases Na-K-ATPase activity via a MAPK/ERK1/2-dependent pathway in rat adult alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol (2008) 0.98
A photoactive isoprenoid diphosphate analogue containing a stable phosphonate linkage: synthesis and biochemical studies with prenyltransferases. J Org Chem (2007) 0.97
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs. J Med Chem (2010) 0.96
A minimalist substrate for enzymatic peptide and protein conjugation. Chembiochem (2009) 0.94
Purification of prenylated proteins by affinity chromatography on cyclodextrin-modified agarose. Anal Biochem (2008) 0.93
Caged protein prenyltransferase substrates: tools for understanding protein prenylation. Chem Biol Drug Des (2008) 0.92
Synthesis and reactivity of 6,7-dihydrogeranylazides: reagents for primary azide incorporation into peptides and subsequent staudinger ligation. Chem Biol Drug Des (2006) 0.89
Enlarging the scope of cell-penetrating prenylated peptides to include farnesylated 'CAAX' box sequences and diverse cell types. Chem Biol Drug Des (2010) 0.89
Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers. Chembiochem (2010) 0.88
Selective labeling of polypeptides using protein farnesyltransferase via rapid oxime ligation. Chem Commun (Camb) (2010) 0.88
Reciprocal regulation of extracellular signal regulated kinase 1/2 and mitogen activated protein kinase phosphatase-3. Toxicol Appl Pharmacol (2008) 0.88
Synthesis of site-specific DNA-protein conjugates and their effects on DNA replication. ACS Chem Biol (2014) 0.87
A combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins. Mol Biosyst (2014) 0.87
Diazotrifluoropropionamido-containing prenylcysteines: syntheses and applications for studying isoprenoid-protein interactions. Org Lett (2003) 0.87
Bioanalysis of eukaryotic organelles. Chem Rev (2013) 0.86
Simultaneous dual protein labeling using a triorthogonal reagent. J Am Chem Soc (2013) 0.86
Transition state analysis of model and enzymatic prenylation reactions. J Am Chem Soc (2007) 0.86
Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. Chem Biol Drug Des (2010) 0.86
The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines. Chem Res Toxicol (2009) 0.85
Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology. Bioorg Med Chem (2010) 0.84
Mitogen activated protein kinases selectively regulate palytoxin-stimulated gene expression in mouse keratinocytes. Toxicol Appl Pharmacol (2003) 0.83
The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif. J Biol Chem (2014) 0.83
Solid-phase synthesis of C-terminal peptide libraries for studying the specificity of enzymatic protein prenylation. Chem Commun (Camb) (2012) 0.83
Investigation of the sequence and length dependence for cell-penetrating prenylated peptides. Bioorg Med Chem Lett (2009) 0.83
Photochemical modulation of Ras-mediated signal transduction using caged farnesyltransferase inhibitors: activation by one- and two-photon excitation. Chembiochem (2012) 0.83
Genotoxic methylating agents modulate extracellular signal regulated kinase activity through MEK-dependent, glutathione-, and DNA methylation-independent mechanisms in lung epithelial cells. Chem Res Toxicol (2003) 0.83
Photoactive analogs of farnesyl diphosphate and related isoprenoids: design and applications in studies of medicinally important isoprenoid-utilizing enzymes. Curr Med Chem (2013) 0.83
Photoaffinity labeling of Ras converting enzyme 1 (Rce1p) using a benzophenone-containing peptide substrate. Bioorg Med Chem (2010) 0.83
Inhibition of mitogen activated protein kinases increases the sensitivity of A549 lung cancer cells to the cytotoxicity induced by a kava chalcone analog. Biochem Biophys Res Commun (2012) 0.82
Chemoselective immobilization of proteins by microcontact printing and bio-orthogonal click reactions. Chembiochem (2013) 0.82
Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues. ACS Chem Biol (2014) 0.82
Photoaffinity labeling of Ras converting enzyme using peptide substrates that incorporate benzoylphenylalanine (Bpa) residues: improved labeling and structural implications. Bioorg Med Chem (2011) 0.82
An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. Anal Biochem (2011) 0.81
A versatile photoactivatable probe designed to label the diphosphate binding site of farnesyl diphosphate utilizing enzymes. Bioorg Med Chem (2009) 0.81
Extracellular signal-regulated kinase transmits palytoxin-stimulated signals leading to altered gene expression in mouse keratinocytes. Toxicol Appl Pharmacol (2002) 0.80
Synthesis of peptides containing C-terminal methyl esters using trityl side-chain anchoring: application to the synthesis of a-factor and a-factor analogs. Org Lett (2012) 0.80
Chemoenzymatic site-specific reversible immobilization and labeling of proteins from crude cellular extract without prior purification using oxime and hydrazine ligation. Curr Protoc Chem Biol (2013) 0.80
Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes. Biochem Biophys Res Commun (2012) 0.80
Preparation and application of G protein gamma subunit-derived peptides incorporating a photoactive isoprenoid. Methods Enzymol (2002) 0.79
Site-specific labeling of proteins and peptides with trans-cyclooctene containing handles capable of tetrazine ligation. Chem Biol Drug Des (2014) 0.79
Nuclear magnetic resonance-based quantification of organic diphosphates. Anal Biochem (2010) 0.79
On-resin conversion of Cys(Acm)-containing peptides to their corresponding Cys(Scm) congeners. J Pept Sci (2010) 0.78
Tumor promoter-induced MMP-13 gene expression in a model of initiated epidermis. Biochem Biophys Res Commun (2004) 0.78
Engineering protein farnesyltransferase for enzymatic protein labeling applications. Bioconjug Chem (2014) 0.78
Covalent protein-oligonucleotide conjugates by copper-free click reaction. Bioorg Med Chem (2012) 0.78
Extracellular signal regulated kinase 5 mediates signals triggered by the novel tumor promoter palytoxin. Toxicol Appl Pharmacol (2009) 0.78
Diazirine-containing photoactivatable isoprenoid: synthesis and application in studies with isoprenylcysteine carboxyl methyltransferase. J Org Chem (2014) 0.77
Exploring routes to stabilize a cationic pyridoxamine in an artificial transaminase: site-directed mutagenesis versus synthetic cofactors. Protein Eng (2002) 0.77
Role of aldehydes in the toxic and mutagenic effects of nitrosamines. Chem Res Toxicol (2013) 0.76
6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning. Org Biomol Chem (2016) 0.75
Synthesis of Peptides Containing C-Terminal Esters Using Trityl Side-Chain Anchoring: Applications to the Synthesis of C-Terminal Ester Analogs of the Saccharomyces cerevisiae Mating Pheromone a-Factor. J Org Chem (2015) 0.75
Application of meta- and para-Phenylenediamine as Enhanced Oxime Ligation Catalysts for Protein Labeling, PEGylation, Immobilization, and Release. Curr Protoc Protein Sci (2015) 0.75
Evaluation of prenylated peptides for use in cellular imaging and biochemical analysis. Methods Mol Biol (2014) 0.75
Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T-cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression. J Med Chem (2020) 0.75
a-Factor analogues containing alkyne- and azide functionalized isoprenoids are efficiently enzymatically processed and retain wild type bioactivity. Bioconjug Chem (2017) 0.75
Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species. Phytochemistry (2008) 0.75