Published in JAMA on October 06, 2004
Antihypertensive Drug/Gene Interactions and CV Events | NCT00005332
Mutations, Hormone Therapy (HRT) and Venous Thromboembolism | NCT00005515
Hormone Replacement Therapy and Prothrombotic Variants | NCT00049933
Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet (2013) 7.13
The epidemiology of venous thromboembolism in the community. Arterioscler Thromb Vasc Biol (2008) 3.50
Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society. Menopause (2008) 1.74
Diabetes mellitus, glycemic control, and risk of atrial fibrillation. J Gen Intern Med (2010) 1.50
Age at menopause, reproductive history, and venous thromboembolism risk among postmenopausal women: the Women's Health Initiative Hormone Therapy clinical trials. Menopause (2014) 1.46
Breast cancer recurrence risk in relation to antidepressant use after diagnosis. Breast Cancer Res Treat (2007) 1.31
Antihypertensive treatment with ACE inhibitors or beta-blockers and risk of incident atrial fibrillation in a general hypertensive population. Am J Hypertens (2009) 1.27
ABO genotype and risk of thrombotic events and hemorrhagic stroke. J Thromb Haemost (2008) 1.18
Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis. Blood (2010) 1.17
Epidemiology of venous thromboembolism. Nat Rev Cardiol (2015) 1.07
The Risk of Venous Thromboembolism with Different Generation of Oral Contraceptives; a Systematic Review and Meta-Analysis. Emerg (Tehran) (2014) 1.04
The epidemiology of venous thromboembolism. J Thromb Thrombolysis (2016) 1.00
Is progestin an independent risk factor for incident venous thromboembolism? A population-based case-control study. Thromb Res (2010) 0.96
The association of smoking with venous thrombosis in women. A population-based, case-control study. Thromb Haemost (2013) 0.91
Estrogen, vascular estrogen receptor and hormone therapy in postmenopausal vascular disease. Biochem Pharmacol (2013) 0.90
Lower risk of cardiovascular events in postmenopausal women taking oral estradiol compared with oral conjugated equine estrogens. JAMA Intern Med (2014) 0.89
Vascular effects of estrogenic menopausal hormone therapy. Rev Recent Clin Trials (2012) 0.85
Changes in remnant and high-density lipoproteins associated with hormone therapy and progression of coronary artery disease in postmenopausal women. Atherosclerosis (2008) 0.80
Breast cancer recurrence in relation to antidepressant use. Cancer Causes Control (2015) 0.77
Smoking, postmenopausal hormone therapy and the risk of venous thrombosis: a population-based, case-control study. Br J Haematol (2013) 0.77
Prevention and treatment of venous thromboembolism during HRT: current perspectives. Int J Gen Med (2014) 0.76
Clinical opinion: the biologic and pharmacologic principles for age-adjusted long-term estrogen therapy. MedGenMed (2006) 0.76
Formulations of hormone therapy and risk of Parkinson's disease. Mov Disord (2014) 0.76
Cross-sectional association of endogenous steroid hormone, sex hormone-binding globulin, and precursor steroid levels with hemostatic factor levels in postmenopausal women. J Thromb Haemost (2016) 0.75
The association of F11 genetic variants with the risk of incident venous thrombosis among women, by statin use. Thromb Haemost (2015) 0.75
Prior hysterectomy and oophorectomy and incident venous thrombosis risk among postmenopausal women: a population-based, case-control study. Menopause (2016) 0.75
Lack of strong effect modification by NFE2L2/CYP3A5/ABO of the risk of venous thrombosis associated with oral hormone therapy. J Thromb Haemost (2013) 0.75
Menopausal hormone therapy and venous thromboembolism. Prz Menopauzalny (2014) 0.75
Hormone replacement treatment choices in complete androgen insensitivity syndrome: an audit of an adult clinic. Endocr Connect (2017) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Opioid prescriptions for chronic pain and overdose: a cohort study. Ann Intern Med (2010) 11.99
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med (2003) 10.06
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies. BMC Med Genomics (2011) 9.20
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol (2003) 8.64
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis. JAMA (2003) 7.42
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Calcium/vitamin D supplementation and cardiovascular events. Circulation (2007) 6.63
The Group Health medical home at year two: cost savings, higher patient satisfaction, and less burnout for providers. Health Aff (Millwood) (2010) 6.60
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA (2005) 6.16
Effectiveness of home blood pressure monitoring, Web communication, and pharmacist care on hypertension control: a randomized controlled trial. JAMA (2008) 6.04
Dementia and Alzheimer disease incidence: a prospective cohort study. Arch Neurol (2002) 5.69
Patient-centered medical home demonstration: a prospective, quasi-experimental, before and after evaluation. Am J Manag Care (2009) 5.65
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am J Epidemiol (2006) 5.28
Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet (2009) 5.20
Glucose levels and risk of dementia. N Engl J Med (2013) 4.95
Inflammation as a risk factor for atrial fibrillation. Circulation (2003) 4.95
Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nat Biotechnol (2013) 4.85
Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol (2010) 4.83
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis. JAMA (2004) 4.71
Temporal trends in the prevalence of diabetic kidney disease in the United States. JAMA (2011) 4.70
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Cystatin C concentration as a risk factor for heart failure in older adults. Ann Intern Med (2005) 4.57
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
Exercise plus behavioral management in patients with Alzheimer disease: a randomized controlled trial. JAMA (2003) 4.54
Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol (2007) 4.47
Impact of endoscopic surveillance on mortality from Barrett's esophagus-associated esophageal adenocarcinomas. Gastroenterology (2013) 4.43
Case-crossover analyses of air pollution exposure data: referent selection strategies and their implications for bias. Epidemiology (2005) 4.42
Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology. Am J Med (2004) 4.38
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genet Med (2013) 4.37
Association between acute care and critical illness hospitalization and cognitive function in older adults. JAMA (2010) 4.36
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Antibiotic use in relation to the risk of breast cancer. JAMA (2004) 4.28
Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet (2011) 4.27
A randomized trial of genotype-guided dosing of acenocoumarol and phenprocoumon. N Engl J Med (2013) 4.27
Assessment. Application of Bloom's taxonomy debunks the "MCAT myth". Science (2008) 4.09
Rising use of diagnostic medical imaging in a large integrated health system. Health Aff (Millwood) (2008) 4.05
Evidence of bias in estimates of influenza vaccine effectiveness in seniors. Int J Epidemiol (2005) 4.04
Personalized medicine in the era of genomics. JAMA (2007) 4.02
Trends in the prevalence and mortality of cognitive impairment in the United States: is there evidence of a compression of cognitive morbidity? Alzheimers Dement (2008) 4.00
Outcomes of planned home births in Washington State: 1989-1996. Obstet Gynecol (2002) 3.99
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93
Lipid-related markers and cardiovascular disease prediction. JAMA (2012) 3.91
Conjugated equine estrogens and coronary heart disease: the Women's Health Initiative. Arch Intern Med (2006) 3.91
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. Am J Hum Genet (2011) 3.85
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency. Circulation (2003) 3.76
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Association of the built environment with physical activity and obesity in older persons. Am J Public Health (2007) 3.60
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative. Am J Epidemiol (2004) 3.53
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation (2009) 3.50
Association of genetic variations with nonfatal venous thrombosis in postmenopausal women. JAMA (2007) 3.50
Estrogen plus progestin and risk of venous thrombosis. JAMA (2004) 3.46